Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2002
  2. Ginkgolides : selective acetylations, translactonization, and biological evaluation. / Jaracz, Stanislav; Strømgaard, Kristian; Nakanishi, Koji.

    In: Journal of Organic Chemistry, Vol. 67, No. 13, 28.06.2002, p. 4623-4626.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Solid-phase synthesis of polyamine toxin analogues : potent and selective antagonists of Ca2+-permeable AMPA receptors. / Kromann, Hasse; Krikstolaityte, Sonata; Andersen, Anne J; Andersen, Kim; Krogsgaard-Larsen, Povl; Jaroszewski, Jerzy W; Egebjerg, Jan; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 45, No. 26, 19.12.2002, p. 5745-5754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Ginkgolide derivatives for photolabeling studies : preparation and pharmacological evaluation. / Strømgaard, Kristian; Saito, D Roland; Shindou, Hideo; Ishii, Satoshi; Shimizu, Takao; Nakanishi, Koji.

    In: Journal of Medicinal Chemistry, Vol. 45, No. 18, 29.08.2002, p. 4038-4046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Solid-phase synthesis and pharmacological evaluation of analogues of PhTX-12-A potent and selective nicotinic acetylcholine receptor antagonist. / Strømgaard, Kristian; Mellor, Ian R; Andersen, Kim; Neagoe, Ioana; Pluteanu, Florentina; Usherwood, Peter N R; Krogsgaard-Larsen, Povl; Jaroszewski, Jerzy W.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 12, No. 8, 22.04.2002, p. 1159-1162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2003
  7. Published

    Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors. / Brier, Tim J; Mellor, Ian R; Tikhonov, Denis B; Neagoe, Ioana; Shao, Zuoyi; Brierley, Matt J; Strømgaard, Kristian; Jaroszewski, Jerzy W; Krogsgaard-Larsen, Povl; Usherwood, Peter N R.

    In: Molecular Pharmacology, Vol. 64, No. 4, 10.2003, p. 954-964.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors. / Ivic, Lidija; Sands, Tristan T J; Fishkin, Nathan; Nakanishi, Koji; Kriegstein, Arnold R; Strømgaard, Kristian.

    In: Journal of Biological Chemistry, Vol. 278, No. 49, 05.12.2003, p. 49279-49285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors. / Mellor, I R; Brier, T J; Pluteanu, F; Strømgaard, K; Saghyan, A; Eldursi, N; Brierley, M J; Andersen, K; Jaroszewski, J W; Krogsgaard-Larsen, P; Usherwood, P N R.

    In: Neuropharmacology, Vol. 44, No. 1, 01.2003, p. 70-80.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Preparation of 7-substituted ginkgolide derivatives : potent platelet activating factor (PAF) receptor antagonists. / Vogensen, Stine Byskov; Strømgaard, Kristian; Shindou, Hideo; Jaracz, Stanislav; Suehiro, Makiko; Ishii, Satoshi; Shimizu, Takao; Nakanishi, Koji.

    In: Journal of Medicinal Chemistry, Vol. 46, No. 4, 13.02.2003, p. 601-608.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2004
  12. Published

    Ginkgolides and glycine receptors : a structure-activity relationship study. / Jaracz, Stanislav; Nakanishi, Koji; Jensen, Anders A.; Strømgaard, Kristian.

    In: Chemistry: A European Journal, Vol. 10, No. 6, 2004, p. 1507-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Site-specific incorporation of unnatural amino acids into proteins. / Strømgaard, Anne; Jensen, Anders A.; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 5, No. 7, 2004, p. 909-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    AMPA receptor ligands : synthetic and pharmacological studies of polyamines and polyamine toxins. / Strømgaard, Kristian; Mellor, Ian.

    In: Medicinal Research Reviews, Vol. 24, No. 5, 09.2004, p. 589-620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba. / Strømgaard, Kristian; Nakanishi, Koji.

    In: Angewandte Chemie International Edition, Vol. 43, No. 13, 19.03.2004, p. 1640-1658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Preparation of a tritiated ginkgolide. / Strømgaard, Kristian; Suehiro, Makiko; Nakanishi, Koji.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 14, No. 22, 15.11.2004, p. 5673-5675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure. / Strømgaard, Kristian; Andersen, TF.

    In: Tetrahedron Letters, Vol. 45, 2004, p. 7929-7933.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2005
  19. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist. / Andersen, Trine F; Vogensen, Stine B; Jensen, Lars S; Knapp, Kolja M; Strømgaard, Kristian.

    In: Bioorganic & Medicinal Chemistry, Vol. 13, No. 17, 01.09.2005, p. 5104-5112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Natural products as tools for studies of ligand-gated ion channels. / Strømgaard, Kristian.

    In: Chemical Record, Vol. 5, No. 4, 2005, p. 229-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Polyamine toxins : development of selective ligands for ionotropic receptors. / Strømgaard, Kristian; Jensen, Lars S; Vogensen, Stine B.

    In: Toxicon, Vol. 45, No. 3, 01.03.2005, p. 249-254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2006
  23. Published

    Uncompetitive antagonism of AMPA receptors : Mechanistic insights from studies of polyamine toxin derivatives. / Andersen, Trine F; Tikhonov, Denis B; Bølcho, Ulrik; Bolshakov, Konstantin; Nelson, Jared K; Pluteanu, Florentina; Mellor, Ian R; Egebjerg, Jan; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 49, No. 18, 07.09.2006, p. 5414-5423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Stoffer fra Tempeltæet (Ginkgo biloba) som redskaber for studier af hjernens funktion. / Jensen, Anders A.; Strømgaard, Kristian.

    In: Dansk Kemi 83, Vol. 87, No. 1, 2006, p. 16-18.

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    Design, synthesis, and pharmacological characterization of polyamine toxin derivatives : potent ligands for the pore-forming region of AMPA receptors. / Jensen, Lars S; Bølcho, Ulrik; Egebjerg, Jan; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 1, No. 4, 04.2006, p. 419-428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Unaturlige aminosyrer skaber ny viden om proteiner. / Rannes, Julie; Andersen, Jacob; Jensen, Anders A.; Christensen, Leif; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2006, p. 28-29.

    Research output: Contribution to journalJournal articleCommunication

  27. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy. / Strømgaard, Kristian; Piazzi, Lorna; Olsen, Christian A; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Magnetic Resonance in Chemistry, Vol. 44, No. 11, 2006, p. 1013-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2007
  29. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists. / Jensen, Anders Asbjørn; Begum, Nasreen; Vogensen, Stine Byskov; Knapp, Kolja Michael; Gundertofte, Klaus; Dzyuba, Sergei V.; Ishii, Hideki; Nakanishi, Koji; Kristiansen, Uffe; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 7, 2007, p. 1610-1617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Expressed protein ligation of ionotropic glutamate receptors. / Jensen, Mette Stougård; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Biopolymers, Vol. 88, No. 4, 2007, p. 602.

    Research output: Contribution to journalConference abstract in journalResearch

  31. 2008
  32. Published

    Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders; Chi, Celestine N.; Olsen, Thomas B.; Pedersen, Søren Wittrup; Røder, Martin U.; Pang, Gar Fai; Clausen, Rasmus Prætorius; Jemth, Per; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 20, 2008, p. 6450-6459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Protein-protein interaktion : et nyt mål for udvikling af lægemidler. / Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2008, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  34. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors. / Frølund, Sidsel Ullerup; Ziegler, Hanne Lindvig; Franzyk, Henrik; Strømgaard, Kristian; Kristensen, Anders Skov; Jaroszewski, Jerzy Witold.

    2008. Poster session presented at Fællesmøde for de danske farmakologiske selskaber 2008, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  36. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling. / Strømgaard, Kristian.

    In: Carlsbergfondet. Aarsskrift, 2008, p. 42-47.

    Research output: Contribution to journalJournal articleCommunication

  37. 2009
  38. Published

    Location of the antidepressant binding site in the serotonin transporter : importance of SER-438 in recognition of citalopram and tricyclic antidepressants. / Andersen, Jacob; Taboureau, Olivier; Hansen, Kasper Bø; Olsen, Lars; Egebjerg, Jan; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 284, No. 15, 2009, p. 10276-10284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters. / Andersen, Jacob; Kristensen, Anders Skov; Bang-Andersen, Benny; Strømgaard, Kristian.

    In: Chemical Communications, No. 25, 2009, p. 3677-3692.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors : Improved antagonistic activity by incorporation of proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Balle, Thomas; Clark, Richard J; Harpsøe, Kasper; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 2009, p. 9498-9512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    Peptides for youth: The proceedings of the 20th American peptide symposium. ed. / Susan Del Valle; Emanuel Escher; William D Lubell. Vol. 611 Springer, 2009. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  42. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. / Bach, Anders; Chi, Celestine N; Pang, Gar Fai; Olsen, Lars; Kristensen, Anders Skov; Jemth, Per; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 51, 2009, p. 9685-9689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    A sequential binding mechanism in a PDZ domain. / Chi, Celestine N; Bach, Anders; Engström, Åke; Wang, Huiqun; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemistry, Vol. 48, No. 30, 2009, p. 7089-7097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Detecting protein-protein interactions in living cells : development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction. / Gottschalk, Marie; Bach, Anders; Hansen, Jakob Lerche; Krogsgaard-Larsen, Povl; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Neurochemical Research, Vol. 34, No. 10, 2009, p. 1729-1737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Synthesis and biological activity of argiotoxin 636 and analogues : selective antagonists for ionotropic glutamate receptors. / Nelson, Jared Keith; Frølund, Sidsel Ullerup; Tikhonov, Dennis B; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 17, 2009, p. 3087-3091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Skræddersyede proteiner : uden naturens begrænsninger. / Strømgaard, Kristian; Jensen, Mette Stougård; Kristensen, Anders Skov.

    In: Lægemiddelforskning, 2009, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

ID: 1302559