Kristian Strømgaard
Professor
Medicinal Chemistry Research
Jagtvej 162, 2100 København Ø, 30, Building: 240
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A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain. / Thorsen, Thor S; Madsen, Kenneth L; Dyhring, Tino; Bach, Anders; Peters, Dan; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.
In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 7, 01.08.2011, p. 590-600.Research output: Contribution to journal › Journal article › Research › peer-review
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A heteromeric snake toxin and the molecular details of pain perception. / Strømgaard, Kristian; Kristensen, Anders Skov.
In: Angewandte Chemie International Edition, Vol. 51, No. 17, 23.04.2012, p. 4009-4011.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. / Bach, Anders*; Clausen, Bettina H; Møller, Magda; Vestergaard, Bente; Chi, Celestine N; Round, Adam; Sørensen, Pernille Louise; Nissen, Klaus Bertram; Kastrup, Jette Sandholm; Gajhede, Michael; Jemth, Per; Kristensen, Anders Skov; Lundström, Patrik; Lambertsen, Kate Lykke; Strømgaard, Kristian* (*Corresponding).
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 9, 28.02.2012, p. 3317-3322.Research output: Contribution to journal › Journal article › Research › peer-review
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A sequential binding mechanism in a PDZ domain. / Chi, Celestine N; Bach, Anders; Engström, Åke; Wang, Huiqun; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.
In: Biochemistry, Vol. 48, No. 30, 2009, p. 7089-7097.Research output: Contribution to journal › Journal article › Research › peer-review
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AMPA receptor ligands : synthetic and pharmacological studies of polyamines and polyamine toxins. / Strømgaard, Kristian; Mellor, Ian.
In: Medicinal Research Reviews, Vol. 24, No. 5, 09.2004, p. 589-620.Research output: Contribution to journal › Journal article › Research › peer-review
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An expanded view of the protein folding landscape of PDZ domains. / Hultqvist, Greta; Pedersen, Søren W; Chi, Celestine N.; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.
In: Biochemical and Biophysical Research Communications, Vol. 421, No. 3, 11.05.2012, p. 550-553.Research output: Contribution to journal › Journal article › Research › peer-review
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Antidepressive lægemidler : nu i 3D. / Andersen, Jacob; Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders Skov.
In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 25-27.Research output: Contribution to journal › Journal article › Communication
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Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes : Discovery of nanomolar, nonselective, and use-dependent antagonists. / Frølund, Sidsel; Bella, Angelo; Kristensen, Anders Skov; Ziegler, Hanne Lindvig; Witt, Matthias; Olsen, Christian Adam; Strømgaard, Kristian; Franzyk, Henrik; Jaroszewski, Jerzy W.
In: Journal of Medicinal Chemistry, Vol. 53, No. 20, 2010, p. 7441-7451.Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. / Chi, Celestine Ngang; Bach, Anders; Engström, Åke; Strømgaard, Kristian; Lundström, Patrik; Ferguson, Neil; Jemth, Per.
In: Journal of Biological Chemistry, Vol. 286, No. 5, 04.02.2011, p. 3597-3606.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders*; Eildal, Jonas Nii Nortey*; Stuhr-Hansen, Nicolai; Deeskamp, Rasmus; Gottschalk, Marie; Pedersen, Søren Wittrup; Kristensen, Anders Skov; Strømgaard, Kristian (*Shared 1st authors).
In: Journal of Medicinal Chemistry, Vol. 54, No. 5, 10.03.2011, p. 1333-1346.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical biology. / Strømgaard, Kristian.
Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 59-74.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Chemistry and biology of terpene trilactones from Ginkgo biloba. / Strømgaard, Kristian; Nakanishi, Koji.
In: Angewandte Chemie International Edition, Vol. 43, No. 13, 19.03.2004, p. 1640-1658.Research output: Contribution to journal › Journal article › Research › peer-review
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Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors. / Brier, Tim J; Mellor, Ian R; Tikhonov, Denis B; Neagoe, Ioana; Shao, Zuoyi; Brierley, Matt J; Strømgaard, Kristian; Jaroszewski, Jerzy W; Krogsgaard-Larsen, Povl; Usherwood, Peter N R.
In: Molecular Pharmacology, Vol. 64, No. 4, 10.2003, p. 954-964.Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. / Chi, Celestine N; Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian; Jemth, Per.
In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28252-28260.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. / Bach, Anders; Chi, Celestine N; Pang, Gar Fai; Olsen, Lars; Kristensen, Anders Skov; Jemth, Per; Strømgaard, Kristian.
In: Angewandte Chemie - International Edition, Vol. 48, No. 51, 2009, p. 9685-9689.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist. / Andersen, Trine F; Vogensen, Stine B; Jensen, Lars S; Knapp, Kolja M; Strømgaard, Kristian.
In: Bioorganic & Medicinal Chemistry, Vol. 13, No. 17, 01.09.2005, p. 5104-5112.Research output: Contribution to journal › Journal article › Research › peer-review
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Design, synthesis, and pharmacological characterization of polyamine toxin derivatives : potent ligands for the pore-forming region of AMPA receptors. / Jensen, Lars S; Bølcho, Ulrik; Egebjerg, Jan; Strømgaard, Kristian.
In: ChemMedChem, Vol. 1, No. 4, 04.2006, p. 419-428.Research output: Contribution to journal › Journal article › Research › peer-review
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Detecting protein-protein interactions in living cells : development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction. / Gottschalk, Marie; Bach, Anders; Hansen, Jakob Lerche; Krogsgaard-Larsen, Povl; Kristensen, Anders Skov; Strømgaard, Kristian.
In: Neurochemical Research, Vol. 34, No. 10, 2009, p. 1729-1737.Research output: Contribution to journal › Journal article › Research › peer-review
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Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors. / Frølund, Sidsel Ullerup; Ziegler, Hanne Lindvig; Franzyk, Henrik; Strømgaard, Kristian; Kristensen, Anders Skov; Jaroszewski, Jerzy Witold.
2008. Poster session presented at Fællesmøde for de danske farmakologiske selskaber 2008, Odense, Denmark.Research output: Contribution to conference › Poster › Research
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Expedient synthesis of 1,3-substituted benzene peptidomimetics. / Bach, Anders; Strømgaard, Kristian.
In: Synthesis, Vol. 2011, No. 5, 08.02.2011, p. 807-815.Research output: Contribution to journal › Journal article › Research › peer-review
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Expressed protein ligation of ionotropic glutamate receptors. / Jensen, Mette Stougård; Kristensen, Anders Skov; Strømgaard, Kristian.
In: Biopolymers, Vol. 88, No. 4, 2007, p. 602.Research output: Contribution to journal › Conference abstract in journal › Research
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From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.
In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.Research output: Contribution to journal › Journal article › Research › peer-review
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General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. / Lucas, Simon; Poulsen, Mette H; Nørager, Niels G; Barslund, Anne F; Bach, Tinna B; Kristensen, Anders S; Strømgaard, Kristian.
In: Journal of Medicinal Chemistry, Vol. 55, No. 22, 26.11.2012, p. 10297-10301.Research output: Contribution to journal › Journal article › Research › peer-review
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Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling. / Strømgaard, Kristian.
In: Carlsbergfondet. Aarsskrift, 2008, p. 42-47.Research output: Contribution to journal › Journal article › Communication
Ginkgolide derivatives for photolabeling studies : preparation and pharmacological evaluation. / Strømgaard, Kristian; Saito, D Roland; Shindou, Hideo; Ishii, Satoshi; Shimizu, Takao; Nakanishi, Koji.
In: Journal of Medicinal Chemistry, Vol. 45, No. 18, 29.08.2002, p. 4038-4046.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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