Kristian Strømgaard
Kristian Strømgaard

Professor


  1. 2010
  2. Published

    Antidepressive lægemidler: nu i 3D

    Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In : Lægemiddelforskning. 2010, p. 25-27

    Research output: Contribution to journalJournal articleCommunication

  3. Published

    Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction

    Bach, Anders & Strømgaard, Kristian, 14 Jan 2010, Patent No. WO2010/004003 (Granted: EP2320927B1; US9241967B2)

    Research output: Patent

  4. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

    Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In : Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Chemical biology

    Strømgaard, Kristian, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 59-74

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  6. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In : Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Rebola, N., Rathje, Mette, Anggono, V., Bach, Anders, Moreira, I. S., Stuhr-Hansen, N., Dyhring, T., Peters, D., Beuming, T., Huganir, R., Weinstein, H., Mulle, C., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 2010, In : Proceedings of the National Academy of Science of the United States of America. 107, 1, p. 413-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter

    Andersen, J., Olsen, L., Hansen, K. B., Taboureau, O., Jørgensen, Flemming Steen, Jørgensen, A. M., Bang-Andersen, B., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2010, In : Journal of Biological Chemistry. 285, 3, p. 2051-2063

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy

    Andersen, N. H., Christensen, Niels Johan, Lassen, P. R., Freedman, T. B. N., Nafie, L. A., Strømgaard, Kristian & Hemmingsen, Lars Bo Stegeager, 2010, In : Chirality. 22, 2, p. 217-223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, Thor Seneca, Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In : Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Textbook of drug design and discovery

    Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.

    Research output: Book/ReportBookEducation

  12. 2009
  13. Published

    A sequential binding mechanism in a PDZ domain

    Chi, C. N., Bach, Anders, Engström, Å., Wang, H., Strømgaard, Kristian, Gianni, S. & Jemth, P., 2009, In : Biochemistry. 48, 30, p. 7089-7097

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In : Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

    Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In : Neurochemical Research. 34, 10, p. 1729-1737

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Location of the antidepressant binding site in the serotonin transporter: importance of SER-438 in recognition of citalopram and tricyclic antidepressants

    Andersen, J., Taboureau, O., Hansen, K. B., Olsen, L., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2009, In : Journal of Biological Chemistry. 284, 15, p. 10276-10284

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors: Improved antagonistic activity by incorporation of proline derivatives

    Armishaw, C., Jensen, Anders A., Balle, T., Clark, R. J., Harpsøe, Kasper, Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, In : Journal of Biological Chemistry. 284, 14, p. 9498-9512

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters

    Andersen, J., Kristensen, Anders Skov, Bang-Andersen, B. & Strømgaard, Kristian, 2009, In : Chemical Communications. 25, p. 3677-3692

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Skræddersyede proteiner: uden naturens begrænsninger

    Strømgaard, Kristian, Jensen, M. S. & Kristensen, Anders Skov, 2009, In : Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

    Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In : Angewandte Chemie - International Edition. 48, 17, p. 3087-3091

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives

    Armishaw, C., Jensen, Anders A., Skonberg, C., Liljefors, T. & Strømgaard, Kristian, 2009, Peptides for youth: The proceedings of the 20th American peptide symposium. Del Valle, S., Escher, E. & Lubell, W. D. (eds.). Springer, Vol. 611. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  22. 2008
  23. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

    Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

    Research output: Contribution to conferencePosterResearch

  24. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: Synthesis and structure-activity relationship studies

    Eildal, J. N. N., Andersen, J., Kristensen, Anders Skov, Jørgensen, A. M., Bang-Andersen, B., Jørgensen, M. & Strømgaard, Kristian, 2008, In : Journal of Medicinal Chemistry. 51, 10, p. 3045-3048

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling

    Strømgaard, Kristian, 2008, In : Carlsbergfondet. Aarsskrift. p. 42-47

    Research output: Contribution to journalJournal articleCommunication

  26. Published

    Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Chi, C. N., Olsen, T. B., Pedersen, S. W., Røder, M. U., Pang, G. F., Clausen, Rasmus Prætorius, Jemth, P. & Strømgaard, Kristian, 2008, In : Journal of Medicinal Chemistry. 51, 20, p. 6450-6459

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Protein-protein interaktion: et nyt mål for udvikling af lægemidler

    Bach, Anders, Gottschalk, M., Kristensen, Anders Skov & Strømgaard, Kristian, 2008, In : Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  28. 2007
  29. Published

    Expressed protein ligation of ionotropic glutamate receptors

    Jensen, M. S., Kristensen, Anders Skov & Strømgaard, Kristian, 2007, In : Biopolymers. 88, 4, p. 602

    Research output: Contribution to journalConference abstract in journalResearch

  30. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists

    Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In : Journal of Medicinal Chemistry. 50, 7, p. 1610-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2006
  32. Published

    Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives

    Andersen, T. F., Tikhonov, D. B., Bølcho, U., Bolshakov, K., Nelson, J. K., Pluteanu, F., Mellor, I. R., Egebjerg, J. & Strømgaard, Kristian, 7 Sep 2006, In : Journal of Medicinal Chemistry. 49, 18, p. 5414-5423 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors

    Jensen, L. S., Bølcho, U., Egebjerg, J. & Strømgaard, Kristian, Apr 2006, In : ChemMedChem. 1, 4, p. 419-428 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy

    Strømgaard, Kristian, Piazzi, L., Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In : Magnetic Resonance in Chemistry. 44, 11, p. 1013-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Stoffer fra Tempeltæet (Ginkgo biloba) som redskaber for studier af hjernens funktion

    Jensen, Anders A. & Strømgaard, Kristian, 2006, In : Dansk Kemi 83. 87, 1, p. 16-18

    Research output: Contribution to journalJournal articleCommunication

  36. Published

    Unaturlige aminosyrer skaber ny viden om proteiner

    Rannes, J., Andersen, J., Jensen, Anders A., Christensen, L. & Strømgaard, Kristian, 2006, In : Lægemiddelforskning. p. 28-29

    Research output: Contribution to journalJournal articleCommunication

  37. 2005
  38. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist

    Andersen, T. F., Vogensen, S. B., Jensen, L. S., Knapp, K. M. & Strømgaard, Kristian, 1 Sep 2005, In : Bioorganic & Medicinal Chemistry. 13, 17, p. 5104-5112 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Polyamine toxins: development of selective ligands for ionotropic receptors

    Strømgaard, Kristian, Jensen, L. S. & Vogensen, S. B., 1 Mar 2005, In : Toxicon. 45, 3, p. 249-254 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Natural products as tools for studies of ligand-gated ion channels

    Strømgaard, Kristian, 2005, In : Chemical Record. 5, 4, p. 229-239 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2004
  42. Published

    Preparation of a tritiated ginkgolide

    Strømgaard, Kristian, Suehiro, M. & Nakanishi, K., 15 Nov 2004, In : Bioorganic & Medicinal Chemistry Letters. 14, 22, p. 5673-5675 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins

    Strømgaard, Kristian & Mellor, I., Sep 2004, In : Medicinal Research Reviews. 24, 5, p. 589-620 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba

    Strømgaard, Kristian & Nakanishi, K., 19 Mar 2004, In : Angewandte Chemie International Edition. 43, 13, p. 1640-1658 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Ginkgolides and glycine receptors: a structure-activity relationship study

    Jaracz, S., Nakanishi, K., Jensen, Anders A. & Strømgaard, Kristian, 2004, In : Chemistry: A European Journal. 10, 6, p. 1507-18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Site-specific incorporation of unnatural amino acids into proteins

    Strømgaard, A., Jensen, Anders A. & Strømgaard, Kristian, 2004, In : ChemBioChem. 5, 7, p. 909-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure

    Strømgaard, Kristian & Andersen, T., 2004, In : Tetrahedron Letters. 45, p. 7929-7933

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559