Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. / Barslund, Anne Fuglsang; Poulsen, Mette Homann; Bach, Tinna Brøbech; Lucas, Simon; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Journal of Natural Products, Vol. 74, No. 3, 2011, p. 483-486.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A sequential binding mechanism in a PDZ domain. / Chi, Celestine N; Bach, Anders; Engström, Åke; Wang, Huiqun; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemistry, Vol. 48, No. 30, 2009, p. 7089-7097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. / Chi, Celestine N; Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28252-28260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Ligand binding by PDZ domains. / Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: BioFactors, Vol. 38, No. 5, 2012, p. 338-348 (Review).

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. / Chi, Celestine Ngang; Bach, Anders; Engström, Åke; Strømgaard, Kristian; Lundström, Patrik; Ferguson, Neil; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 286, No. 5, 04.02.2011, p. 3597-3606.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations. / Eildal, Jonas N N; Hultqvist, Greta; Balle, Thomas; Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Gianni, Stefano; Strømgaard, Kristian; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 135, No. 35, 04.09.2013, p. 12998-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95. / Eildal, Jonas N N; Bach, Anders; Dogan, Jakob; Ye, Fei; Zhang, Mingjie; Jemth, Per; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 16, 2015, p. 64–69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. / Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian; Kastrup, Jette S; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 69, No. Pt 4, 04.2013, p. 587-94.

    Research output: Contribution to journalJournal articleResearch

  10. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes : Discovery of nanomolar, nonselective, and use-dependent antagonists. / Frølund, Sidsel; Bella, Angelo; Kristensen, Anders Skov; Ziegler, Hanne Lindvig; Witt, Matthias; Olsen, Christian Adam; Strømgaard, Kristian; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 20, 2010, p. 7441-7451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors. / Frølund, Sidsel Ullerup; Ziegler, Hanne Lindvig; Franzyk, Henrik; Strømgaard, Kristian; Kristensen, Anders Skov; Jaroszewski, Jerzy Witold.

    2008. Poster session presented at Fællesmøde for de danske farmakologiske selskaber 2008, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  12. Published

    Detecting protein-protein interactions in living cells : development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction. / Gottschalk, Marie; Bach, Anders; Hansen, Jakob Lerche; Krogsgaard-Larsen, Povl; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Neurochemical Research, Vol. 34, No. 10, 2009, p. 1729-1737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. / Haq, S Raza; Chi, Celestine N; Bach, Anders; Dogan, Jakob; Engström, Åke; Hultqvist, Greta; Karlsson, O. Andreas; Lundström, Patrik; Montemiglio, Linda Celeste; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 134, No. 1, 01.2012, p. 599-605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS. / Haugaard-Kedstrom, L. M.; Albertsen, L.; Gil, F. Abalde; Ivarsson, Y.; Stromgaard, K.; Kedström, Linda Maria Haugaard.

    In: Journal of Peptide Science, Vol. 20, No. Suppl. 1, YO11, 09.2014, p. s39.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Energetic pathway sampling in a protein interaction domain. / Hultqvist, Greta; Haq, S. Raza; Punekar, Avinash S.; Chi, Celestine N.; Engström, Ake; Bach, Anders; Strømgaard, Kristian; Selmer, Maria; Gianni, Stefano; Jemth, Per.

    In: Structure, Vol. 21, No. 7, 25.06.2013, p. 1193-1202.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    An expanded view of the protein folding landscape of PDZ domains. / Hultqvist, Greta; Pedersen, Søren W; Chi, Celestine N.; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemical and Biophysical Research Communications, Vol. 421, No. 3, 11.05.2012, p. 550-553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins. / Kachel, Hamid S.; Franzyk, Henrik; Stromgaard, Kristian; Tikhonov, Denis B.; Mellor, Ian R.

    In: Biophysical Society. Annual Meeting. Abstracts, Vol. 106, No. 2, 28.01.2014, p. 338A-338A.

    Research output: Contribution to journalJournal articleResearch

  18. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation. / Kristensen, Anders S; Andersen, Jacob; Jørgensen, Trine N; Sørensen, Lena; Eriksen, Jacob; Løland, Claus Juul; Strømgaard, Kristian; Gether, Ulrik.

    In: Pharmacological Reviews, Vol. 63, No. 3, 01.09.2011, p. 585-640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Textbook of drug design and discovery. / Krogsgaard-Larsen, Povl; Strømgaard, Kristian; Madsen, Ulf.

    4 ed. Boca Raton : CRC Press, 2010. 460 p.

    Research output: Book/ReportBookEducation

  20. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. / Lucas, Simon; Poulsen, Mette H; Nørager, Niels G; Barslund, Anne F; Bach, Tinna B; Kristensen, Anders S; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 22, 26.11.2012, p. 10297-10301.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin. / Maric, Hans-Michael; Kasaragod, Vikram Babu; Hausrat, Torben Johann; Kneussel, Matthias; Tretter, Verena; Strømgaard, Kristian; Schindelin, Hermann.

    In: Nature Communications, Vol. 5, 5767, 22.12.2014, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. / Maric, Hans-Michael; Kasaragod, Vikram Babu; Kedström, Linda Maria Haugaard; Hausrat, Torben Johann; Kneussel, Matthias; Schindelin, Hermann; Strømgaard, Kristian.

    In: Angewandte Chemie (International ed. in English), Vol. 54, No. 2, 07.01.2015, p. 490-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95 : quantitative characterization of interactions. / Møller, Thor C; Wirth, Volker F; Roberts, Nina Ingerslev; Bender, Julia; Bach, Anders; Jacky, Birgitte P S; Strømgaard, Kristian; Deussing, Jan M; Schwartz, Thue W; Martinez, Karen L.

    In: PLOS ONE, Vol. 8, No. 5, e63352, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Synthesis and biological activity of argiotoxin 636 and analogues : selective antagonists for ionotropic glutamate receptors. / Nelson, Jared Keith; Frølund, Sidsel Ullerup; Tikhonov, Dennis B; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 17, 2009, p. 3087-3091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family. / Nissen, Klaus B; Kedström, Linda Maria Haugaard; Wilbek, Theis S; Nielsen, Line S; Åberg, Emma; Kristensen, Anders S; Bach, Anders; Jemth, Per; Strømgaard, Kristian.

    In: PLOS ONE, Vol. 10, No. 2, e0117668, 2015, p. 1-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559