Kristian Strømgaard
Kristian Strømgaard

Professor


  1. Published

    Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein

    Zhang, H., Xiong, X., Boesgaard, Michael Worch, Underwood, C. R., Bräuner-Osborne, Hans & Strømgaard, Kristian, 7 Jun 2017, In : ChemMedChem. 12, 11, p. 830-834 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

    Zhang, H., Nielsen, Alexander Lund, Boesgaard, Michael Worch, Harpsøe, Kasper, Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner-Osborne, Hans, Gloriam, David E. & Strømgaard, Kristian, 5 Aug 2018, In : European Journal of Medicinal Chemistry. 156, p. 847-860

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors

    Xiong, X., Zhang, H., Underwood, C. R., Harpsøe, Kasper, Gardella, T. J., Wöldike, M. F., Mannstadt, M., Gloriam, David E., Bräuner-Osborne, Hans & Strømgaard, Kristian, 2016, In : Nature Chemistry. 8, 11, p. 1035-1041 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure–Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors

    Xiong, X., Poulsen, Mette Homann, Hussein, R. A., Nørager, N. G. & Strømgaard, Kristian, Dec 2014, In : ChemMedChem. 9, 12, p. 2661-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Polyamine toxins from spiders and wasps: Polyamine toxins from spiders and wasps

    Xiong, X. & Strømgaard, Kristian, 2015, Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer, Japan, p. 201-214 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  6. Published

    Structure–Activity Relationship Studies of the Natural Product G q/11 Protein Inhibitor YM-254890

    Xiong, X. F., Zhang, H., Boesgaard, Michael Worch, Underwood, C. R., Bräuner-Osborne, Hans & Strømgaard, Kristian, Apr 2019, In : ChemMedChem. 14, 8, p. 865-870

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1

    Wilbek, T. S., Skovgaard, T., Sorrell, F. J., Knapp, S., Berthelsen, J. & Strømgaard, Kristian, 2 Jan 2015, In : ChemBioChem. 16, 1, p. 59-63 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Ligand binding to the PDZ domains of postsynaptic density protein 95

    Toto, A., Pedersen, S. W., Karlsson, O. A., Moran, G. E., Andersson, E., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., May 2016, In : Protein Engineering Design and Selection (Print). 29, 5, p. 169-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Rebola, N., Rathje, Mette, Anggono, V., Bach, Anders, Moreira, I. S., Stuhr-Hansen, N., Dyhring, T., Peters, D., Beuming, T., Huganir, R., Weinstein, H., Mulle, C., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 2010, In : Proceedings of the National Academy of Science of the United States of America. 107, 1, p. 413-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Dyhring, T., Bach, Anders, Peters, D., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 1 Aug 2011, In : Combinatorial Chemistry & High Throughput Screening. 14, 7, p. 590-600 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In : The Journal of Biological Chemistry. 287, 52, p. 43694-43707 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites

    Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, 18 Apr 2014, In : ACS chemical biology. 9, 4, p. 935-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In : Journal of Biological Chemistry. 287, p. 43694-43707 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Synthetic and mechanistic insight into nosylation of glycine residues

    Stuhr-Hansen, N., Sølling, Theis Ivan & Strømgaard, Kristian, 14 Apr 2013, In : Organic & Biomolecular Chemistry. 11, 14, p. 2288-2293 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids

    Stuhr-Hansen, N., Padrah, S. & Strømgaard, Kristian, 2014, In : Tetrahedron Letters. 55, 30, p. 4149-4151 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines

    Stuhr-Hansen, N., Bork, N. & Strømgaard, Kristian, 14 Aug 2014, In : Organic & Biomolecular Chemistry. 12, 30, p. 5745-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Synthesis of symmetrical and non-symmetrical bivalent neurotransmitter ligands

    Stuhr-Hansen, N., Andersen, J., Thygesen, Mikkel Boas & Strømgaard, Kristian, 2016, In : ChemistrySelect. 1, 3, p. 407-413 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Preparation of peptide thioesters through fmoc-based solid-phase peptide synthesis by using amino thioesters

    Stuhr-Hansen, N., Wilbek, T. S. & Strømgaard, Kristian, 1 Aug 2013, In : European Journal of Organic Chemistry. 2013, 24, p. 5290-5294 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Skræddersyede proteiner: uden naturens begrænsninger

    Strømgaard, Kristian, Jensen, M. S. & Kristensen, Anders Skov, 2009, In : Lægemiddelforskning. p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    A heteromeric snake toxin and the molecular details of pain perception

    Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In : Angewandte Chemie International Edition. 51, 17, p. 4009-4011

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Chemical biology

    Strømgaard, Kristian, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 59-74

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  22. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95

    Strømgaard, Kristian, Bach, Anders & Nissen, K. B., 4 Jun 2015, IPC No. A61K38/17 , Patent No. WO2015/078477A1, Priority date 1 Dec 2013, Priority No. DK/2013/70735

    Research output: Patent

  23. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, Oct 2017, In : Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, 20 Jan 2017, In : European Journal of Neuroscience. 45, 2, p. 238-248 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Gynther, M., Bjerre, A., Gram, M. G., Marschner, L., Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, 2017, In : Neurochemical Research. 42, 12, p. 3401-3413 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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