Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    A heteromeric snake toxin and the molecular details of pain perception. / Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Angewandte Chemie International Edition, Vol. 51, No. 17, 23.04.2012, p. 4009-4011.

    Research output: Contribution to journalJournal article

  2. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. / Bach, Anders*; Clausen, Bettina H; Møller, Magda; Vestergaard, Bente; Chi, Celestine N; Round, Adam; Sørensen, Pernille Louise; Nissen, Klaus Bertram; Kastrup, Jette Sandholm; Gajhede, Michael; Jemth, Per; Kristensen, Anders Skov; Lundström, Patrik; Lambertsen, Kate Lykke; Strømgaard, Kristian* (*Corresponding).

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 9, 28.02.2012, p. 3317-3322.

    Research output: Contribution to journalJournal article

  3. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY. / Albertsen, Louise; Østergaard, Søren; Paulsson, Johan F; Norrild, Jens Chr.; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 8, No. 9, 09.2013, p. 1505-13.

    Research output: Contribution to journalJournal article

  4. Published

    An expanded view of the protein folding landscape of PDZ domains. / Hultqvist, Greta; Pedersen, Søren W; Chi, Celestine N.; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemical and Biophysical Research Communications, Vol. 421, No. 3, 11.05.2012, p. 550-553.

    Research output: Contribution to journalJournal article

  5. Published

    Binding of ArgTX-636 in the NMDA receptor ion channel. / Poulsen, Mette H; Andersen, Jacob; Christensen, Rune; Hansen, Kasper Bø; Traynelis, Stephen F; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Molecular Biology, Vol. 427, No. 1, 16.01.2015, p. 176-89.

    Research output: Contribution to journalJournal article

  6. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter. / Andersen, Jacob; Ladefoged, Lucy Kate; Wang, Danyang; Kristensen, Trine N Bjerre; Bang-Andersen, Benny; Kristensen, Anders S; Schiøtt, Birgit; Strømgaard, Kristian.

    In: A C S Chemical Neuroscience, Vol. 6, No. 11, 18.11.2015, p. 1892-900.

    Research output: Contribution to journalJournal article

  7. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter. / Andersen, Jacob; Ringsted, Kristoffer B; Bang-Andersen, Benny; Strømgaard, Kristian; Kristensen, Anders S.

    In: Scientific Reports, Vol. 5, 15650, 2015, p. 1-12.

    Research output: Contribution to journalJournal article

  8. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites. / Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders S.

    In: ACS chemical biology, Vol. 9, No. 4, 18.04.2014, p. 935-44.

    Research output: Contribution to journalJournal article

  9. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. / Maric, Hans-Michael; Kasaragod, Vikram Babu; Kedström, Linda Maria Haugaard; Hausrat, Torben Johann; Kneussel, Matthias; Schindelin, Hermann; Strømgaard, Kristian.

    In: Angewandte Chemie (International ed. in English), Vol. 54, No. 2, 07.01.2015, p. 490-4.

    Research output: Contribution to journalJournal article

  10. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications. / Albertsen, Louise; Andersen, J.J.; Paulsson, J.F.; Thomsen, J.K.; Norrild, Jens Chr.; Strømgaard, K.

    In: A C S Medicinal Chemistry Letters, Vol. 4, No. 12, 12.12.2013, p. 1228-1232.

    Research output: Contribution to journalJournal article

  11. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor. / Nissen, Klaus B; Andersen, Julie J; Haugaard-Kedström, Linda Maria; Bach, Anders; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 58, 2015, p. 1575-1580.

    Research output: Contribution to journalJournal article

  12. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons. / Nørager, Niels Grøn; Jensen, Christel Barker; Rathje, Mette; Andersen, Jacob; Madsen, Kenneth Lindegaard; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: A C S Chemical Biology, Vol. 8, No. 9, 20.09.2013, p. 2033-2041.

    Research output: Contribution to journalJournal article

  13. Published

    Energetic pathway sampling in a protein interaction domain. / Hultqvist, Greta; Haq, S. Raza; Punekar, Avinash S.; Chi, Celestine N.; Engström, Ake; Bach, Anders; Strømgaard, Kristian; Selmer, Maria; Gianni, Stefano; Jemth, Per.

    In: Structure, Vol. 21, No. 7, 25.06.2013, p. 1193-1202.

    Research output: Contribution to journalJournal article

  14. Published

    Evaluation of PhTX-74 as Subtype-Selective Inhibitor of GluA2-Containing AMPA Receptors. / Poulsen, Mette Homann; Lucas, Simon; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Molecular Pharmacology, Vol. 85, No. 2, 02.2014, p. 261-268.

    Research output: Contribution to journalJournal article

  15. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids. / Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Strømgaard, Kristian.

    In: Tetrahedron Letters, Vol. 55, No. 30, 2014, p. 4149-4151.

    Research output: Contribution to journalJournal article

  16. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95. / Strømgaard, Kristian (Inventor); Bach, Anders (Inventor); Nissen, Klaus Bertram (Inventor).

    IPC No.: A61K38/17 . Patent No.: WO2015/078477A1.

    Research output: Patent

  17. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. / Lucas, Simon; Poulsen, Mette H; Nørager, Niels G; Barslund, Anne F; Bach, Tinna B; Kristensen, Anders S; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 22, 26.11.2012, p. 10297-10301.

    Research output: Contribution to journalJournal article

  18. Submitted
  19. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1. / Wilbek, Theis S; Skovgaard, Tine; Sorrell, Fiona J; Knapp, Stefan; Berthelsen, Jens; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 16, No. 1, 02.01.2015, p. 59-63.

    Research output: Contribution to journalJournal article

  20. Published

    Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation. / Rannversson, Hafsteinn; Wilson, Pamela; Kristensen, Kristina Birch; Sinning, Steffen; Kristensen, Anders Skov; Strømgaard, Kristian; Andersen, Jacob.

    In: The Journal of Biological Chemistry, Vol. 290, No. 23, 05.06.2015, p. 14582-94.

    Research output: Contribution to journalJournal article

  21. Published

    Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin. / Poulsen, Mette H; Lucas, Simon; Strømgaard, Kristian; Kristensen, Anders S.

    In: Neurochemical Research, Vol. 39, No. 10, 22.02.2014, p. 1906-1913.

    Research output: Contribution to journalJournal article

  22. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders S.

    In: The Journal of Biological Chemistry, Vol. 287, No. 52, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal article

  23. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 287, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal article

  24. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. / Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian; Kastrup, Jette S; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 69, No. Pt 4, 04.2013, p. 587-94.

    Research output: Contribution to journalJournal article

  25. Published

    Ligand binding by PDZ domains. / Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: BioFactors, Vol. 38, No. 5, 2012, p. 338-348 (Review).

    Research output: Contribution to journalJournal article

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