Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    Uncompetitive antagonism of AMPA receptors : Mechanistic insights from studies of polyamine toxin derivatives. / Andersen, Trine F; Tikhonov, Denis B; Bølcho, Ulrik; Bolshakov, Konstantin; Nelson, Jared K; Pluteanu, Florentina; Mellor, Ian R; Egebjerg, Jan; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 49, No. 18, 07.09.2006, p. 5414-5423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Unaturlige aminosyrer skaber ny viden om proteiner. / Rannes, Julie; Andersen, Jacob; Jensen, Anders A.; Christensen, Leif; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2006, p. 28-29.

    Research output: Contribution to journalJournal articleCommunication

  3. Published
  4. Published

    Textbook of drug design and discovery. / Krogsgaard-Larsen, Povl; Strømgaard, Kristian; Madsen, Ulf.

    4 ed. Boca Raton : CRC Press, 2010. 460 p.

    Research output: Book/ReportBookEducation

  5. Published

    Synthetic and mechanistic insight into nosylation of glycine residues. / Stuhr-Hansen, Nicolai; Sølling, Theis Ivan; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 11, No. 14, 14.04.2013, p. 2288-2293.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure. / Strømgaard, Kristian; Andersen, TF.

    In: Tetrahedron Letters, Vol. 45, 2004, p. 7929-7933.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group. / Pedersen, Søren W; Armishaw, Christopher J; Strømgaard, Kristian.

    Peptide synthesis and applications. Vol. 1047 Humana Press, 2013. p. 65-80 (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  8. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    Peptides for youth: The proceedings of the 20th American peptide symposium. ed. / Susan Del Valle; Emanuel Escher; William D Lubell. Vol. 611 Springer, 2009. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  9. Published

    Synthesis and biological activity of argiotoxin 636 and analogues : selective antagonists for ionotropic glutamate receptors. / Nelson, Jared Keith; Frølund, Sidsel Ullerup; Tikhonov, Dennis B; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 17, 2009, p. 3087-3091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1. / Bach, Anders; Stuhr-Hansen, Nicolai; Thorsen, Thor S; Bork, Nicolai; Moreira, Irina S; Frydenvang, Karla; Padrah, Shahrokh; Christensen, S Brøgger; Madsen, Kenneth L; Weinstein, Harel; Gether, Ulrik; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 8, No. 19, 2010, p. 4281-4288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structure-activity relationship studies of argiotoxins : selective and potent inhibitors of ionotropic glutamate receptors. / Poulsen, Mette H; Lucas, Simon; Bach, Tinna B; Barslund, Anne F; Wenzler, Claudius; Jensen, Christel B; Kristensen, Anders S; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 14.02.2013, p. 1171-1181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy. / Andersen, Niels Højmark; Christensen, Niels Johan; Lassen, Peter Rygaard; Freedman, Teresa B.N.; Nafie, Laurence A.; Strømgaard, Kristian; Hemmingsen, Lars Bo Stegeager.

    In: Chirality, Vol. 22, No. 2, 2010, p. 217-223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Stoffer fra Tempeltæet (Ginkgo biloba) som redskaber for studier af hjernens funktion. / Jensen, Anders A.; Strømgaard, Kristian.

    In: Dansk Kemi 83, Vol. 87, No. 1, 2006, p. 16-18.

    Research output: Contribution to journalJournal articleCommunication

  14. Published

    Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. / Barslund, Anne Fuglsang; Poulsen, Mette Homann; Bach, Tinna Brøbech; Lucas, Simon; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Journal of Natural Products, Vol. 74, No. 3, 2011, p. 483-486.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Small molecules from spiders used as chemical probes. / Olsen, Christian Adam; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie International Edition, Vol. 50, No. 48, 25.11.2011, p. 11296-11311.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Skræddersyede proteiner : uden naturens begrænsninger. / Strømgaard, Kristian; Jensen, Mette Stougård; Kristensen, Anders Skov.

    In: Lægemiddelforskning, 2009, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  17. Published

    Site-specific incorporation of unnatural amino acids into proteins. / Strømgaard, Anne; Jensen, Anders A.; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 5, No. 7, 2004, p. 909-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. / Haq, S Raza; Chi, Celestine N; Bach, Anders; Dogan, Jakob; Engström, Åke; Hultqvist, Greta; Karlsson, O. Andreas; Lundström, Patrik; Montemiglio, Linda Celeste; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 134, No. 1, 01.2012, p. 599-605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation. / Kristensen, Anders S; Andersen, Jacob; Jørgensen, Trine N; Sørensen, Lena; Eriksen, Jacob; Løland, Claus Juul; Strømgaard, Kristian; Gether, Ulrik.

    In: Pharmacological Reviews, Vol. 63, No. 3, 01.09.2011, p. 585-640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Recombinant production of peptide C-terminal α-amides using an engineered intein. / Albertsen, Louise; Shaw, Allan C; Norrild, Jens Chr.; Strømgaard, Kristian.

    In: Bioconjugate Chemistry, Vol. 24, No. 11, 20.11.2013, p. 1883-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters. / Andersen, Jacob; Kristensen, Anders Skov; Bang-Andersen, Benny; Strømgaard, Kristian.

    In: Chemical Communications, No. 25, 2009, p. 3677-3692.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors : Improved antagonistic activity by incorporation of proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Balle, Thomas; Clark, Richard J; Harpsøe, Kasper; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 2009, p. 9498-9512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy. / Strømgaard, Kristian; Piazzi, Lorna; Olsen, Christian A; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Magnetic Resonance in Chemistry, Vol. 44, No. 11, 2006, p. 1013-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Protein-protein interaktion : et nyt mål for udvikling af lægemidler. / Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2008, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations. / Eildal, Jonas N N; Hultqvist, Greta; Balle, Thomas; Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Gianni, Stefano; Strømgaard, Kristian; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 135, No. 35, 04.09.2013, p. 12998-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists. / Jensen, Anders Asbjørn; Begum, Nasreen; Vogensen, Stine Byskov; Knapp, Kolja Michael; Gundertofte, Klaus; Dzyuba, Sergei V.; Ishii, Hideki; Nakanishi, Koji; Kristiansen, Uffe; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 7, 2007, p. 1610-1617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Preparation of peptide thioesters through fmoc-based solid-phase peptide synthesis by using amino thioesters. / Stuhr-Hansen, N.; Wilbek, T.S.; Strømgaard, K.

    In: European Journal of Organic Chemistry, Vol. 2013, No. 24, 01.08.2013, p. 5290-5294.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Preparation of a tritiated ginkgolide. / Strømgaard, Kristian; Suehiro, Makiko; Nakanishi, Koji.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 14, No. 22, 15.11.2004, p. 5673-5675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Polyamine toxins : development of selective ligands for ionotropic receptors. / Strømgaard, Kristian; Jensen, Lars S; Vogensen, Stine B.

    In: Toxicon, Vol. 45, No. 3, 01.03.2005, p. 249-254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95 : quantitative characterization of interactions. / Møller, Thor C; Wirth, Volker F; Roberts, Nina Ingerslev; Bender, Julia; Bach, Anders; Jacky, Birgitte P S; Strømgaard, Kristian; Deussing, Jan M; Schwartz, Thue W; Martinez, Karen L.

    In: PLOS ONE, Vol. 8, No. 5, e63352, 2013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Natural products as tools for studies of ligand-gated ion channels. / Strømgaard, Kristian.

    In: Chemical Record, Vol. 5, No. 4, 2005, p. 229-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. / Andersen, Jacob; Olsen, Lars; Hansen, Kasper Bø; Taboureau, Olivier; Jørgensen, Flemming Steen; Jørgensen, Anne Marie; Bang-Andersen, Benny; Egebjerg, Jan; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 285, No. 3, 2010, p. 2051-2063.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew D; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 19.07.2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders; Chi, Celestine N.; Olsen, Thomas B.; Pedersen, Søren Wittrup; Røder, Martin U.; Pang, Gar Fai; Clausen, Rasmus Prætorius; Jemth, Per; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 20, 2008, p. 6450-6459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published
  36. Published

    Location of the antidepressant binding site in the serotonin transporter : importance of SER-438 in recognition of citalopram and tricyclic antidepressants. / Andersen, Jacob; Taboureau, Olivier; Hansen, Kasper Bø; Olsen, Lars; Egebjerg, Jan; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 284, No. 15, 2009, p. 10276-10284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Ligand binding by PDZ domains. / Chi, Celestine N.; Bach, Anders; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: BioFactors, Vol. 38, No. 5, 2012, p. 338-348 (Review).

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. / Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian; Kastrup, Jette S; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 69, No. Pt 4, 04.2013, p. 587-94.

    Research output: Contribution to journalJournal articleResearch

  39. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders S.

    In: The Journal of Biological Chemistry, Vol. 287, No. 52, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters : mutational studies of the S1 substrate binding pocket. / Sørensen, Lena; Andersen, Jacob; Thomsen, Mette; Hansen, Stinna M.R.; Zhao, Xiaobei; Sandelin, Albin Gustav; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 287, 2012, p. 43694-43707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Improving the stability of alpha-conotoxin AuIB through N-to-C cyclization : The effect of linker length on stability and activity at nicotinic acetylcholine receptors. / Armishaw, Christopher J; Jensen, Anders A; Balle, Lena D; Scott, Krystle C M; Sørensen, Lena; Strømgaard, Kristian.

    In: Antioxidants & Redox Signaling, Vol. 14, No. 1, 2011, p. 65-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. / Thorsen, Thor S; Madsen, Kenneth L; Rebola, Nelson; Rathje, Mette; Anggono, Victor; Bach, Anders; Moreira, Irina S; Stuhr-Hansen, Nicolai; Dyhring, Tino; Peters, Dan; Beuming, Thijs; Huganir, Richard; Weinstein, Harel; Mulle, Christophe; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 107, No. 1, 2010, p. 413-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Submitted
  44. Published

    Ginkgolides and glycine receptors : a structure-activity relationship study. / Jaracz, Stanislav; Nakanishi, Koji; Jensen, Anders A.; Strømgaard, Kristian.

    In: Chemistry: A European Journal, Vol. 10, No. 6, 2004, p. 1507-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling. / Strømgaard, Kristian.

    In: Carlsbergfondet. Aarsskrift, 2008, p. 42-47.

    Research output: Contribution to journalJournal articleCommunication

  46. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors. / Lucas, Simon; Poulsen, Mette H; Nørager, Niels G; Barslund, Anne F; Bach, Tinna B; Kristensen, Anders S; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 22, 26.11.2012, p. 10297-10301.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Expressed protein ligation of ionotropic glutamate receptors. / Jensen, Mette Stougård; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Biopolymers, Vol. 88, No. 4, 2007, p. 602.

    Research output: Contribution to journalConference abstract in journalResearch

  49. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics. / Bach, Anders; Strømgaard, Kristian.

    In: Synthesis, Vol. 2011, No. 5, 08.02.2011, p. 807-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Energetic pathway sampling in a protein interaction domain. / Hultqvist, Greta; Haq, S. Raza; Punekar, Avinash S.; Chi, Celestine N.; Engström, Ake; Bach, Anders; Strømgaard, Kristian; Selmer, Maria; Gianni, Stefano; Jemth, Per.

    In: Structure, Vol. 21, No. 7, 25.06.2013, p. 1193-1202.

    Research output: Contribution to journalJournal articleResearchpeer-review

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