Kristian Strømgaard

Kristian Strømgaard

Professor


  1. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain. / Thorsen, Thor S; Madsen, Kenneth L; Dyhring, Tino; Bach, Anders; Peters, Dan; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 7, 01.08.2011, p. 590-600.

    Research output: Contribution to journalJournal article

  2. Published

    A heteromeric snake toxin and the molecular details of pain perception. / Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Angewandte Chemie International Edition, Vol. 51, No. 17, 23.04.2012, p. 4009-4011.

    Research output: Contribution to journalJournal article

  3. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. / Bach, Anders*; Clausen, Bettina H; Møller, Magda; Vestergaard, Bente; Chi, Celestine N; Round, Adam; Sørensen, Pernille Louise; Nissen, Klaus Bertram; Kastrup, Jette Sandholm; Gajhede, Michael; Jemth, Per; Kristensen, Anders Skov; Lundström, Patrik; Lambertsen, Kate Lykke; Strømgaard, Kristian* (*Corresponding).

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 9, 28.02.2012, p. 3317-3322.

    Research output: Contribution to journalJournal article

  4. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY. / Albertsen, Louise; Østergaard, Søren; Paulsson, Johan F; Norrild, Jens Chr.; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 8, No. 9, 09.2013, p. 1505-13.

    Research output: Contribution to journalJournal article

  5. Published

    A sequential binding mechanism in a PDZ domain. / Chi, Celestine N; Bach, Anders; Engström, Åke; Wang, Huiqun; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemistry, Vol. 48, No. 30, 2009, p. 7089-7097.

    Research output: Contribution to journalJournal article

  6. Published

    AMPA receptor ligands : synthetic and pharmacological studies of polyamines and polyamine toxins. / Strømgaard, Kristian; Mellor, Ian.

    In: Medicinal Research Reviews, Vol. 24, No. 5, 09.2004, p. 589-620.

    Research output: Contribution to journalJournal article

  7. Published

    An expanded view of the protein folding landscape of PDZ domains. / Hultqvist, Greta; Pedersen, Søren W; Chi, Celestine N.; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemical and Biophysical Research Communications, Vol. 421, No. 3, 11.05.2012, p. 550-553.

    Research output: Contribution to journalJournal article

  8. Published

    Antidepressive lægemidler : nu i 3D. / Andersen, Jacob; Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 25-27.

    Research output: Contribution to journalJournal article

  9. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes : Discovery of nanomolar, nonselective, and use-dependent antagonists. / Frølund, Sidsel; Bella, Angelo; Kristensen, Anders Skov; Ziegler, Hanne Lindvig; Witt, Matthias; Olsen, Christian Adam; Strømgaard, Kristian; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 20, 2010, p. 7441-7451.

    Research output: Contribution to journalJournal article

  10. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. / Chi, Celestine Ngang; Bach, Anders; Engström, Åke; Strømgaard, Kristian; Lundström, Patrik; Ferguson, Neil; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 286, No. 5, 04.02.2011, p. 3597-3606.

    Research output: Contribution to journalJournal article

  11. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders*; Eildal, Jonas Nii Nortey*; Stuhr-Hansen, Nicolai; Deeskamp, Rasmus; Gottschalk, Marie; Pedersen, Søren Wittrup; Kristensen, Anders Skov; Strømgaard, Kristian (*Shared 1st authors).

    In: Journal of Medicinal Chemistry, Vol. 54, No. 5, 10.03.2011, p. 1333-1346.

    Research output: Contribution to journalJournal article

  12. Published

    Chemical biology. / Strømgaard, Kristian.

    Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 59-74.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  13. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba. / Strømgaard, Kristian; Nakanishi, Koji.

    In: Angewandte Chemie International Edition, Vol. 43, No. 13, 19.03.2004, p. 1640-1658.

    Research output: Contribution to journalJournal article

  14. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. / Chi, Celestine N; Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28252-28260.

    Research output: Contribution to journalJournal article

  15. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. / Bach, Anders; Chi, Celestine N; Pang, Gar Fai; Olsen, Lars; Kristensen, Anders Skov; Jemth, Per; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 51, 2009, p. 9685-9689.

    Research output: Contribution to journalJournal article

  16. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist. / Andersen, Trine F; Vogensen, Stine B; Jensen, Lars S; Knapp, Kolja M; Strømgaard, Kristian.

    In: Bioorganic & Medicinal Chemistry, Vol. 13, No. 17, 01.09.2005, p. 5104-5112.

    Research output: Contribution to journalJournal article

  17. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications. / Albertsen, Louise; Andersen, J.J.; Paulsson, J.F.; Thomsen, J.K.; Norrild, Jens Chr.; Strømgaard, K.

    In: A C S Medicinal Chemistry Letters, Vol. 4, No. 12, 12.12.2013, p. 1228-1232.

    Research output: Contribution to journalJournal article

  18. Published

    Design, synthesis, and pharmacological characterization of polyamine toxin derivatives : potent ligands for the pore-forming region of AMPA receptors. / Jensen, Lars S; Bølcho, Ulrik; Egebjerg, Jan; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 1, No. 4, 04.2006, p. 419-428.

    Research output: Contribution to journalJournal article

  19. Published
  20. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons. / Nørager, Niels Grøn; Jensen, Christel Barker; Rathje, Mette; Andersen, Jacob; Madsen, Kenneth Lindegaard; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: A C S Chemical Biology, Vol. 8, No. 9, 20.09.2013, p. 2033-2041.

    Research output: Contribution to journalJournal article

  21. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors. / Frølund, Sidsel Ullerup; Ziegler, Hanne Lindvig; Franzyk, Henrik; Strømgaard, Kristian; Kristensen, Anders Skov; Jaroszewski, Jerzy Witold.

    2008. Poster session presented at Fællesmøde for de danske farmakologiske selskaber 2008, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Energetic pathway sampling in a protein interaction domain. / Hultqvist, Greta; Haq, S. Raza; Punekar, Avinash S.; Chi, Celestine N.; Engström, Ake; Bach, Anders; Strømgaard, Kristian; Selmer, Maria; Gianni, Stefano; Jemth, Per.

    In: Structure, Vol. 21, No. 7, 25.06.2013, p. 1193-1202.

    Research output: Contribution to journalJournal article

  23. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics. / Bach, Anders; Strømgaard, Kristian.

    In: Synthesis, Vol. 2011, No. 5, 08.02.2011, p. 807-815.

    Research output: Contribution to journalJournal article

  24. Published

    Expressed protein ligation of ionotropic glutamate receptors. / Jensen, Mette Stougård; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Biopolymers, Vol. 88, No. 4, 2007, p. 602.

    Research output: Contribution to journalConference abstract in journal

  25. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.

    Research output: Contribution to journalJournal article

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