Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2004
  2. Published

    Ginkgolides and glycine receptors : a structure-activity relationship study. / Jaracz, Stanislav; Nakanishi, Koji; Jensen, Anders A.; Strømgaard, Kristian.

    In: Chemistry: A European Journal, Vol. 10, No. 6, 2004, p. 1507-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Site-specific incorporation of unnatural amino acids into proteins. / Strømgaard, Anne; Jensen, Anders A.; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 5, No. 7, 2004, p. 909-16.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure. / Strømgaard, Kristian; Andersen, TF.

    In: Tetrahedron Letters, Vol. 45, 2004, p. 7929-7933.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba. / Strømgaard, Kristian; Nakanishi, Koji.

    In: Angewandte Chemie International Edition, Vol. 43, No. 13, 19.03.2004, p. 1640-1658.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    AMPA receptor ligands : synthetic and pharmacological studies of polyamines and polyamine toxins. / Strømgaard, Kristian; Mellor, Ian.

    In: Medicinal Research Reviews, Vol. 24, No. 5, 09.2004, p. 589-620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Preparation of a tritiated ginkgolide. / Strømgaard, Kristian; Suehiro, Makiko; Nakanishi, Koji.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 14, No. 22, 15.11.2004, p. 5673-5675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2005
  9. Published

    Natural products as tools for studies of ligand-gated ion channels. / Strømgaard, Kristian.

    In: Chemical Record, Vol. 5, No. 4, 2005, p. 229-239.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Polyamine toxins : development of selective ligands for ionotropic receptors. / Strømgaard, Kristian; Jensen, Lars S; Vogensen, Stine B.

    In: Toxicon, Vol. 45, No. 3, 01.03.2005, p. 249-254.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist. / Andersen, Trine F; Vogensen, Stine B; Jensen, Lars S; Knapp, Kolja M; Strømgaard, Kristian.

    In: Bioorganic & Medicinal Chemistry, Vol. 13, No. 17, 01.09.2005, p. 5104-5112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2006
  13. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy. / Strømgaard, Kristian; Piazzi, Lorna; Olsen, Christian A; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Magnetic Resonance in Chemistry, Vol. 44, No. 11, 2006, p. 1013-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Stoffer fra Tempeltæet (Ginkgo biloba) som redskaber for studier af hjernens funktion. / Jensen, Anders A.; Strømgaard, Kristian.

    In: Dansk Kemi 83, Vol. 87, No. 1, 2006, p. 16-18.

    Research output: Contribution to journalJournal articleCommunication

  15. Published

    Unaturlige aminosyrer skaber ny viden om proteiner. / Rannes, Julie; Andersen, Jacob; Jensen, Anders A.; Christensen, Leif; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2006, p. 28-29.

    Research output: Contribution to journalJournal articleCommunication

  16. Published

    Design, synthesis, and pharmacological characterization of polyamine toxin derivatives : potent ligands for the pore-forming region of AMPA receptors. / Jensen, Lars S; Bølcho, Ulrik; Egebjerg, Jan; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 1, No. 4, 04.2006, p. 419-428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Uncompetitive antagonism of AMPA receptors : Mechanistic insights from studies of polyamine toxin derivatives. / Andersen, Trine F; Tikhonov, Denis B; Bølcho, Ulrik; Bolshakov, Konstantin; Nelson, Jared K; Pluteanu, Florentina; Mellor, Ian R; Egebjerg, Jan; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 49, No. 18, 07.09.2006, p. 5414-5423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2007
  19. Published

    Expressed protein ligation of ionotropic glutamate receptors. / Jensen, Mette Stougård; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Biopolymers, Vol. 88, No. 4, 2007, p. 602.

    Research output: Contribution to journalConference abstract in journalResearch

  20. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists. / Jensen, Anders Asbjørn; Begum, Nasreen; Vogensen, Stine Byskov; Knapp, Kolja Michael; Gundertofte, Klaus; Dzyuba, Sergei V.; Ishii, Hideki; Nakanishi, Koji; Kristiansen, Uffe; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 7, 2007, p. 1610-1617.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2008
  22. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors. / Frølund, Sidsel Ullerup; Ziegler, Hanne Lindvig; Franzyk, Henrik; Strømgaard, Kristian; Kristensen, Anders Skov; Jaroszewski, Jerzy Witold.

    2008. Poster session presented at Fællesmøde for de danske farmakologiske selskaber 2008, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  23. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram : Synthesis and structure-activity relationship studies. / Eildal, Jonas Nii Nortey; Andersen, Jacob; Kristensen, Anders Skov; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 10, 2008, p. 3045-3048.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling. / Strømgaard, Kristian.

    In: Carlsbergfondet. Aarsskrift, 2008, p. 42-47.

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    Modified peptides as potent inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders; Chi, Celestine N.; Olsen, Thomas B.; Pedersen, Søren Wittrup; Røder, Martin U.; Pang, Gar Fai; Clausen, Rasmus Prætorius; Jemth, Per; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 20, 2008, p. 6450-6459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Protein-protein interaktion : et nyt mål for udvikling af lægemidler. / Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Lægemiddelforskning, 2008, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  27. 2009
  28. Published

    A sequential binding mechanism in a PDZ domain. / Chi, Celestine N; Bach, Anders; Engström, Åke; Wang, Huiqun; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Biochemistry, Vol. 48, No. 30, 2009, p. 7089-7097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. / Bach, Anders; Chi, Celestine N; Pang, Gar Fai; Olsen, Lars; Kristensen, Anders Skov; Jemth, Per; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 51, 2009, p. 9685-9689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Detecting protein-protein interactions in living cells : development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction. / Gottschalk, Marie; Bach, Anders; Hansen, Jakob Lerche; Krogsgaard-Larsen, Povl; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Neurochemical Research, Vol. 34, No. 10, 2009, p. 1729-1737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Location of the antidepressant binding site in the serotonin transporter : importance of SER-438 in recognition of citalopram and tricyclic antidepressants. / Andersen, Jacob; Taboureau, Olivier; Hansen, Kasper Bø; Olsen, Lars; Egebjerg, Jan; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 284, No. 15, 2009, p. 10276-10284.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Rational design of a-conotoxin analogues targeting a7 nicotinic acetylcholine receptors : Improved antagonistic activity by incorporation of proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Balle, Thomas; Clark, Richard J; Harpsøe, Kasper; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    In: Journal of Biological Chemistry, Vol. 284, No. 14, 2009, p. 9498-9512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters. / Andersen, Jacob; Kristensen, Anders Skov; Bang-Andersen, Benny; Strømgaard, Kristian.

    In: Chemical Communications, No. 25, 2009, p. 3677-3692.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Skræddersyede proteiner : uden naturens begrænsninger. / Strømgaard, Kristian; Jensen, Mette Stougård; Kristensen, Anders Skov.

    In: Lægemiddelforskning, 2009, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  35. Published

    Synthesis and biological activity of argiotoxin 636 and analogues : selective antagonists for ionotropic glutamate receptors. / Nelson, Jared Keith; Frølund, Sidsel Ullerup; Tikhonov, Dennis B; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 17, 2009, p. 3087-3091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Synthesis and biological activity of novel a-conotoxin analogues incorporating substituted proline derivatives. / Armishaw, Christopher; Jensen, Anders Asbjørn; Skonberg, Christian; Liljefors, Tommy; Strømgaard, Kristian.

    Peptides for youth: The proceedings of the 20th American peptide symposium. ed. / Susan Del Valle; Emanuel Escher; William D Lubell. Vol. 611 Springer, 2009. p. 179-180 (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  37. 2010
  38. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes : Discovery of nanomolar, nonselective, and use-dependent antagonists. / Frølund, Sidsel; Bella, Angelo; Kristensen, Anders Skov; Ziegler, Hanne Lindvig; Witt, Matthias; Olsen, Christian Adam; Strømgaard, Kristian; Franzyk, Henrik; Jaroszewski, Jerzy W.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 20, 2010, p. 7441-7451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Chemical biology. / Strømgaard, Kristian.

    Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 59-74.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  40. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. / Chi, Celestine N; Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28252-28260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. / Thorsen, Thor S; Madsen, Kenneth L; Rebola, Nelson; Rathje, Mette; Anggono, Victor; Bach, Anders; Moreira, Irina S; Stuhr-Hansen, Nicolai; Dyhring, Tino; Peters, Dan; Beuming, Thijs; Huganir, Richard; Weinstein, Harel; Mulle, Christophe; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 107, No. 1, 2010, p. 413-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. / Andersen, Jacob; Olsen, Lars; Hansen, Kasper Bø; Taboureau, Olivier; Jørgensen, Flemming Steen; Jørgensen, Anne Marie; Bang-Andersen, Benny; Egebjerg, Jan; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Journal of Biological Chemistry, Vol. 285, No. 3, 2010, p. 2051-2063.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy. / Andersen, Niels Højmark; Christensen, Niels Johan; Lassen, Peter Rygaard; Freedman, Teresa B.N.; Nafie, Laurence A.; Strømgaard, Kristian; Hemmingsen, Lars Bo Stegeager.

    In: Chirality, Vol. 22, No. 2, 2010, p. 217-223.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1. / Bach, Anders; Stuhr-Hansen, Nicolai; Thorsen, Thor S; Bork, Nicolai; Moreira, Irina S; Frydenvang, Karla; Padrah, Shahrokh; Christensen, S Brøgger; Madsen, Kenneth L; Weinstein, Harel; Gether, Ulrik; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 8, No. 19, 2010, p. 4281-4288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Textbook of drug design and discovery. / Krogsgaard-Larsen, Povl; Strømgaard, Kristian; Madsen, Ulf.

    4 ed. Boca Raton : CRC Press, 2010. 460 p.

    Research output: Book/ReportBookEducation

  46. Published

    Modified peptides as potent inhibitors of the PSD-95/NMDA receptor interaction. / Bach, Anders (Inventor); Strømgaard, Kristian (Inventor).

    Patent No.: WO2010/004003 (Granted: EP2320927B1; US9241967B2).

    Research output: PatentResearch

  47. Published

    Antidepressive lægemidler : nu i 3D. / Andersen, Jacob; Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 25-27.

    Research output: Contribution to journalJournal articleCommunication

  48. 2011
  49. Published

    Improving the stability of alpha-conotoxin AuIB through N-to-C cyclization : The effect of linker length on stability and activity at nicotinic acetylcholine receptors. / Armishaw, Christopher J; Jensen, Anders A; Balle, Lena D; Scott, Krystle C M; Sørensen, Lena; Strømgaard, Kristian.

    In: Antioxidants & Redox Signaling, Vol. 14, No. 1, 2011, p. 65-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata. / Barslund, Anne Fuglsang; Poulsen, Mette Homann; Bach, Tinna Brøbech; Lucas, Simon; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Journal of Natural Products, Vol. 74, No. 3, 2011, p. 483-486.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. / Chi, Celestine Ngang; Bach, Anders; Engström, Åke; Strømgaard, Kristian; Lundström, Patrik; Ferguson, Neil; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 286, No. 5, 04.02.2011, p. 3597-3606.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Expedient synthesis of 1,3-substituted benzene peptidomimetics. / Bach, Anders; Strømgaard, Kristian.

    In: Synthesis, Vol. 2011, No. 5, 08.02.2011, p. 807-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders*; Eildal, Jonas Nii Nortey*; Stuhr-Hansen, Nicolai; Deeskamp, Rasmus; Gottschalk, Marie; Pedersen, Søren Wittrup; Kristensen, Anders Skov; Strømgaard, Kristian (*Shared 1st authors).

    In: Journal of Medicinal Chemistry, Vol. 54, No. 5, 10.03.2011, p. 1333-1346.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew D; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 19.07.2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain. / Thorsen, Thor S; Madsen, Kenneth L; Dyhring, Tino; Bach, Anders; Peters, Dan; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 7, 01.08.2011, p. 590-600.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation. / Kristensen, Anders S; Andersen, Jacob; Jørgensen, Trine N; Sørensen, Lena; Eriksen, Jacob; Løland, Claus Juul; Strømgaard, Kristian; Gether, Ulrik.

    In: Pharmacological Reviews, Vol. 63, No. 3, 01.09.2011, p. 585-640.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Small molecules from spiders used as chemical probes. / Olsen, Christian Adam; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie International Edition, Vol. 50, No. 48, 25.11.2011, p. 11296-11311.

    Research output: Contribution to journalReviewResearchpeer-review

  58. 2012
  59. Submitted
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ID: 1302559