Kristian Strømgaard
Kristian Strømgaard

Professor


  1. 2016
  2. Published

    Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands

    Andersen, J., Ladefoged, L. K., Kristensen, T. N. B., Munro, L., Grouleff, J., Stuhr-Hansen, N., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 19 Oct 2016, In : A C S Chemical Neuroscience. 7, 10, p. 1406-1417 12 p.

    Research output: Contribution to journalJournal article

  3. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

    Andreasen T., Jesper, Nasser, A., Caballero Puntiverio, Maitane, Sahlholt, M., Bach, Anders, Gynther, M., Strømgaard, Kristian & Pickering, Darryl S, 5 Jun 2016, In : European Journal of Pharmacology. 780, p. 166-73 8 p.

    Research output: Contribution to journalJournal article

  4. Published

    Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    Bach, Anders, Pedersen, T. B. & Strømgaard, Kristian, 2016, In : MedChemComm. 7, 3, p. 531-536 6 p.

    Research output: Contribution to journalJournal article

  5. Published

    Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

    Cheng, J., Sahani, S., Hausrat, T. J., Yang, J., Ji, H., Schmarowski, N., Endle, H., Liu, X., Li, Y., Böttche, R., Radyushkin, K., Maric, H. M., Hoerder-Suabedissen, A., Molnár, Z., Prouvot, P., Trimbuch, T., Ninnemann, O., Huai, J., Fan, W., Visentin, B., Sabbadini, R., Strømgaard, Kristian, Stroh, A., Luhmann, H. J., Kneussel, M., Nitsch, R. & Vogt, J., 5 Oct 2016, In : Neuron. 92, 1, p. 126-142 17 p.

    Research output: Contribution to journalJournal article

  6. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In : British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journalJournal article

  7. Published

    Importance of a Conserved Lys/Arg Residue for Ligand/PDZ Domain Interactions as Examined by Protein Semisynthesis

    Pedersen, S. W., Moran, G. E., Sereikaité, Vita, Kedström, L. M. H. & Strømgaard, Kristian, 17 Oct 2016, In : ChemBioChem. 17, 20, p. 1936-1944 9 p.

    Research output: Contribution to journalJournal article

  8. Published

    Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter

    Rannversson, H., Andersen, J., Hall, L. S., Bang-Andersen, B., Park, M., Huber, T., Sakmar, T. P. & Strømgaard, Kristian, 19 Apr 2016, In : Nature Communications. 7, p. 1-9 9 p., 11261.

    Research output: Contribution to journalJournal article

  9. Published

    Synthesis of symmetrical and non-symmetrical bivalent neurotransmitter ligands

    Stuhr-Hansen, N., Andersen, J., Thygesen, Mikkel Boas & Strømgaard, Kristian, 2016, In : ChemistrySelect. 1, 3, p. 407-413 7 p.

    Research output: Contribution to journalJournal article

  10. Published

    Ligand binding to the PDZ domains of postsynaptic density protein 95

    Toto, A., Pedersen, S. W., Karlsson, O. A., Moran, G. E., Andersson, E., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., May 2016, In : Protein Engineering Design and Selection (Print). 29, 5, p. 169-75 7 p.

    Research output: Contribution to journalJournal article

  11. Published

    Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors

    Xiong, X., Zhang, H., Underwood, C. R., Harpsøe, Kasper, Gardella, T. J., Wöldike, M. F., Mannstadt, M., Gloriam, David E., Bräuner-Osborne, Hans & Strømgaard, Kristian, 2016, In : Nature Chemistry. 8, 11, p. 1035-1041 7 p.

    Research output: Contribution to journalJournal article

  12. 2015
  13. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter

    Andersen, J., Ladefoged, L. K., Wang, Danyang, Kristensen, T. N. B., Bang-Andersen, B., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 18 Nov 2015, In : A C S Chemical Neuroscience. 6, 11, p. 1892-900 9 p.

    Research output: Contribution to journalJournal article

  14. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

    Andersen, J., Ringsted, K. B., Bang-Andersen, B., Strømgaard, Kristian & Kristensen, Anders Skov, 2015, In : Scientific Reports. 5, p. 1-12 12 p., 15650.

    Research output: Contribution to journalJournal article

  15. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    Eildal, J. N. N., Bach, Anders, Dogan, J., Ye, F., Zhang, M., Jemth, P. & Strømgaard, Kristian, 2015, In : ChemBioChem. 16, p. 64–69 6 p.

    Research output: Contribution to journalJournal article

  16. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors

    Maric, H., Kasaragod, V. B., Kedström, L. M. H., Hausrat, T. J., Kneussel, M., Schindelin, H. & Strømgaard, Kristian, 7 Jan 2015, In : Angewandte Chemie (International ed. in English). 54, 2, p. 490-4 5 p.

    Research output: Contribution to journalJournal article

  17. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor

    Nissen, K. B., Andersen, J. J., Haugaard-Kedström, L. M., Bach, Anders & Strømgaard, Kristian, 2015, In : Journal of Medicinal Chemistry. 58, p. 1575-1580 6 p.

    Research output: Contribution to journalJournal article

  18. Published

    Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family

    Nissen, K. B., Kedström, L. M. H., Wilbek, T. S., Nielsen, L. S., Åberg, E., Kristensen, Anders Skov, Bach, Anders, Jemth, P. & Strømgaard, Kristian, 2015, In : PLOS ONE. 10, 2, p. 1-17 17 p., e0117668.

    Research output: Contribution to journalJournal article

  19. Published

    Binding of ArgTX-636 in the NMDA receptor ion channel

    Poulsen, M. H., Andersen, J., Christensen, R., Hansen, K. B., Traynelis, S. F., Strømgaard, Kristian & Kristensen, Anders Skov, 16 Jan 2015, In : Journal of Molecular Biology. 427, 1, p. 176-89 14 p.

    Research output: Contribution to journalJournal article

  20. Published

    Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation

    Rannversson, H., Wilson, P., Kristensen, K. B., Sinning, S., Kristensen, Anders Skov, Strømgaard, Kristian & Andersen, J., 5 Jun 2015, In : The Journal of Biological Chemistry. 290, 23, p. 14582-94 13 p.

    Research output: Contribution to journalJournal article

  21. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95

    Strømgaard, Kristian, Bach, Anders & Nissen, K. B., 4 Jun 2015, IPC No. A61K38/17 , Patent No. WO2015/078477A1, Priority date 1 Dec 2013, Priority No. DK/2013/70735

    Research output: Patent

  22. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1

    Wilbek, T. S., Skovgaard, T., Sorrell, F. J., Knapp, S., Berthelsen, J. & Strømgaard, Kristian, 2 Jan 2015, In : ChemBioChem. 16, 1, p. 59-63 5 p.

    Research output: Contribution to journalJournal article

  23. Published

    Polyamine toxins from spiders and wasps: Polyamine toxins from spiders and wasps

    Xiong, X. & Strømgaard, Kristian, 2015, Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer, Japan, p. 201-214 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. 2014
  25. Published

    Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (prozac)

    Andersen, J., Stuhr-Hansen, N., Dorvil, Linda Grønborg, Koldsø, H., Schiøtt, B., Strømgaard, Kristian & Kristensen, Anders Skov, May 2014, In : Molecular Pharmacology. 85, 5, p. 703-14 12 p.

    Research output: Contribution to journalJournal article

  26. Published

    THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS

    Haugaard-Kedstrom, L. M., Albertsen, L., Gil, F. A., Ivarsson, Y., Strømgaard, Kristian & Kedström, L. M. H., Sep 2014, In : Journal of Peptide Science. 20, Suppl. 1, p. s39 1 p., YO11.

    Research output: Contribution to journalConference abstract in journal

  27. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

    Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In : Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

    Research output: Contribution to journalJournal article

  28. Published

    Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin

    Maric, H., Kasaragod, V. B., Hausrat, T. J., Kneussel, M., Tretter, V., Strømgaard, Kristian & Schindelin, H., 22 Dec 2014, In : Nature Communications. 5, p. 1-11 11 p., 5767.

    Research output: Contribution to journalJournal article

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