Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2015
  2. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. / Maric, Hans-Michael; Kasaragod, Vikram Babu; Kedström, Linda Maria Haugaard; Hausrat, Torben Johann; Kneussel, Matthias; Schindelin, Hermann; Strømgaard, Kristian.

    In: Angewandte Chemie (International ed. in English), Vol. 54, No. 2, 07.01.2015, p. 490-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1. / Wilbek, Theis S; Skovgaard, Tine; Sorrell, Fiona J; Knapp, Stefan; Berthelsen, Jens; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 16, No. 1, 02.01.2015, p. 59-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter. / Andersen, Jacob; Ringsted, Kristoffer B; Bang-Andersen, Benny; Strømgaard, Kristian; Kristensen, Anders S.

    In: Scientific Reports, Vol. 5, 15650, 2015, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor. / Nissen, Klaus B; Andersen, Julie J; Haugaard-Kedström, Linda Maria; Bach, Anders; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 58, 2015, p. 1575-1580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Polyamine toxins from spiders and wasps : Polyamine toxins from spiders and wasps. / Xiong, Xiaofeng; Strømgaard, Kristian.

    Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer, Japan, 2015. p. 201-214.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95. / Eildal, Jonas N N; Bach, Anders; Dogan, Jakob; Ye, Fei; Zhang, Mingjie; Jemth, Per; Strømgaard, Kristian.

    In: ChemBioChem, Vol. 16, 2015, p. 64–69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family. / Nissen, Klaus B; Kedström, Linda Maria Haugaard; Wilbek, Theis S; Nielsen, Line S; Åberg, Emma; Kristensen, Anders S; Bach, Anders; Jemth, Per; Strømgaard, Kristian.

    In: PLOS ONE, Vol. 10, No. 2, e0117668, 2015, p. 1-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2014
  10. Published

    Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin. / Maric, Hans-Michael; Kasaragod, Vikram Babu; Hausrat, Torben Johann; Kneussel, Matthias; Tretter, Verena; Strømgaard, Kristian; Schindelin, Hermann.

    In: Nature Communications, Vol. 5, 5767, 22.12.2014, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structure–Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors. / Xiong, Xiaofeng; Poulsen, Mette H; Hussein, Rama A; Nørager, Niels G; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 9, No. 12, 12.2014, p. 2661-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS. / Haugaard-Kedstrom, L. M.; Albertsen, L.; Gil, F. Abalde; Ivarsson, Y.; Stromgaard, K.; Kedström, Linda Maria Haugaard.

    In: Journal of Peptide Science, Vol. 20, No. Suppl. 1, YO11, 09.2014, p. s39.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines. / Stuhr-Hansen, Nicolai; Bork, Nicolai; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 12, No. 30, 14.08.2014, p. 5745-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors. / Nørager, Niels G; Poulsen, Mette H; Jensen, Anna G; Jeppesen, Nanna S; Kristensen, Anders S; Strømgaard, Kristian.

    In: Journal of Medicinal Chemistry, Vol. 57, No. 11, 12.06.2014, p. 4940-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (prozac). / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda Grønborg; Koldsø, Heidi; Schiøtt, Birgit; Strømgaard, Kristian; Kristensen, Anders S.

    In: Molecular Pharmacology, Vol. 85, No. 5, 05.2014, p. 703-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites. / Sørensen, Lena; Strømgaard, Kristian; Kristensen, Anders S.

    In: ACS chemical biology, Vol. 9, No. 4, 18.04.2014, p. 935-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin. / Poulsen, Mette H; Lucas, Simon; Strømgaard, Kristian; Kristensen, Anders S.

    In: Neurochemical Research, Vol. 39, No. 10, 22.02.2014, p. 1906-1913.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Evaluation of PhTX-74 as Subtype-Selective Inhibitor of GluA2-Containing AMPA Receptors. / Poulsen, Mette Homann; Lucas, Simon; Strømgaard, Kristian; Kristensen, Anders Skov.

    In: Molecular Pharmacology, Vol. 85, No. 2, 02.2014, p. 261-268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins. / Kachel, Hamid S.; Franzyk, Henrik; Stromgaard, Kristian; Tikhonov, Denis B.; Mellor, Ian R.

    In: Biophysical Society. Annual Meeting. Abstracts, Vol. 106, No. 2, 28.01.2014, p. 338A-338A.

    Research output: Contribution to journalJournal articleResearch

  20. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids. / Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Strømgaard, Kristian.

    In: Tetrahedron Letters, Vol. 55, No. 30, 2014, p. 4149-4151.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations. / Pedersen, Søren W; Pedersen, Stine B; Anker, Louise; Hultqvist, Greta; Kristensen, Anders S; Jemth, Per; Strømgaard, Kristian.

    In: Nature Communications, Vol. 5, 3215, 2014, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain. / Pedersen, Søren W; Hultqvist, Greta; Strømgaard, Kristian; Jemth, Per.

    In: PLOS ONE, Vol. 9, No. 4, e95619, 2014, p. 1-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2013
  24. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications. / Albertsen, Louise; Andersen, J.J.; Paulsson, J.F.; Thomsen, J.K.; Norrild, Jens Chr.; Strømgaard, K.

    In: A C S Medicinal Chemistry Letters, Vol. 4, No. 12, 12.12.2013, p. 1228-1232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Recombinant production of peptide C-terminal α-amides using an engineered intein. / Albertsen, Louise; Shaw, Allan C; Norrild, Jens Chr.; Strømgaard, Kristian.

    In: Bioconjugate Chemistry, Vol. 24, No. 11, 20.11.2013, p. 1883-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons. / Nørager, Niels Grøn; Jensen, Christel Barker; Rathje, Mette; Andersen, Jacob; Madsen, Kenneth Lindegaard; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: A C S Chemical Biology, Vol. 8, No. 9, 20.09.2013, p. 2033-2041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations. / Eildal, Jonas N N; Hultqvist, Greta; Balle, Thomas; Stuhr-Hansen, Nicolai; Padrah, Shahrokh; Gianni, Stefano; Strømgaard, Kristian; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 135, No. 35, 04.09.2013, p. 12998-3007.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY. / Albertsen, Louise; Østergaard, Søren; Paulsson, Johan F; Norrild, Jens Chr.; Strømgaard, Kristian.

    In: ChemMedChem, Vol. 8, No. 9, 09.2013, p. 1505-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559