Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2018
  2. Published

    Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations

    Sereikaité, Vita, Jensen, T. M. T., Bartling, Christian Reinhard Otto, Jemth, P., Pless, Stephan & Strømgaard, Kristian, 18 Oct 2018, In : ChemBioChem. 19, 20, p. 2136-2145

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Controlling Ca2+ Permeable alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Photochromic Ion Channel Blockers

    Norager, N. G., Poulsen, Mette Homann & Strømgaard, Kristian, 13 Sep 2018, In : Journal of Medicinal Chemistry. 61, 17, p. 8048-8053

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

    Zhang, H., Nielsen, Alexander Lund, Boesgaard, M. W., Harpsøe, Kasper, Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner-Osborne, Hans, Gloriam, David E. & Strømgaard, Kristian, 5 Aug 2018, In : European Journal of Medicinal Chemistry. 156, p. 847-860

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Peptide Modulation of Acid-Sensing Ion Channels

    Borg, Christian Bernsen, Haugaard-Kedstrom, L. M., Lynagh, T., Strømgaard, Kristian & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conferencePosterResearch

  6. Published

    Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease

    Jensen, T. M. T., Albertsen, L., Bartling, Christian Reinhard Otto, Haugaard-kedström, L. M. & Strømgaard, Kristian, 2018, In : ChemBioChem. 19, 11, p. 1119-1122 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms

    Bleem, A., Christiansen, G., Madsen, D. J., Maric, H., Strømgaard, Kristian, Bryers, J. D., Daggett, V., Meyer, R. L. & Otzen, D. E., 2018, In : Journal of Molecular Biology. 430, 20, p. 3751-3763 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    Mapping the Binding Site for Escitalopram and Paroxetine in the Human Serotonin Transporter Using Genetically Encoded Photo-Cross-Linkers

    Rannversson, H., Andersen, J., Bang-Andersen, B. & Strømgaard, Kristian, 20 Oct 2017, In : ACS chemical biology. 12, 10, p. 2558-2562 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  10. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, Oct 2017, In : Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Site-Specific Phosphorylation of PSD-95 PDZ Domains Reveals Fine-Tuned Regulation of Protein-Protein Interactions

    Pedersen, S. W., Albertsen, L., Moran, G. E., Levesque, B., Pedersen, S. B., Bartels, L., Wapenaar, H., Ye, F., Zhang, M., Bowen, M. E. & Strømgaard, Kristian, 15 Sep 2017, In : ACS chemical biology. 12, 9, p. 2313-2323 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein

    Zhang, H., Xiong, X., Boesgaard, M. W., Underwood, C. R., Bräuner-Osborne, Hans & Strømgaard, Kristian, 7 Jun 2017, In : ChemMedChem. 12, 11, p. 830-834 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors

    Roszko, K. L., Bi, R., Gorvin, C. M., Bräuner-Osborne, Hans, Xiong, X., Inoue, A., Thakker, R. V., Strømgaard, Kristian, Gardella, T. & Mannstadt, M., 9 Feb 2017, In : JCI insight. 2, 3, 15 p., e91079.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Stoichiometry of Toxin Binding to Acid-Sensing Ion Channels

    Borg, Christian Bernsen, Lynagh, T., Haugaard-Kedstrom, L. M., Strømgaard, Kristian & Pless, Stephan, 3 Feb 2017, In : Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 420A-420A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, 20 Jan 2017, In : European Journal of Neuroscience. 45, 2, p. 238-248 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Gynther, M., Bjerre, A., Gram, M. G., Marschner, L., Strømgaard, Kristian, Mogensen, Jesper & Pickering, Darryl S, 2017, In : Neurochemical Research. 42, 12, p. 3401-3413 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission

    Maric, H. M., Hausrat, T. J., Neubert, F., Dalby, N. O., Doose, S., Sauer, M., Kneussel, M. & Strømgaard, Kristian, 2017, In : Nature Chemical Biology. 13, p. 153-160 11 p., 2246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression

    Kucharz, Krzysztof, Søndergaard Rasmussen, I., Bach, Anders, Strømgaard, Kristian & Lauritzen, Martin, 2017, In : Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1820-1828

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Targeting PSD-95 as a Novel Approach in the Treatment of Stroke

    Haugaard-Kedstrom, L. M., Fernandes, E. F. A. & Strømgaard, Kristian, 2017, Neuroprotective Therapy for Stroke and Ischemic Disease . Springer, p. 157-184 28 p. (Springer Series in Translational Stroke Research).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. 2016
  21. Published

    Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands

    Andersen, J., Ladefoged, L. K., Kristensen, T. N. B., Munro, L., Grouleff, J., Stuhr-Hansen, N., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 19 Oct 2016, In : A C S Chemical Neuroscience. 7, 10, p. 1406-1417 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Importance of a Conserved Lys/Arg Residue for Ligand/PDZ Domain Interactions as Examined by Protein Semisynthesis

    Pedersen, S. W., Moran, G. E., Sereikaité, Vita, Kedström, L. M. H. & Strømgaard, Kristian, 17 Oct 2016, In : ChemBioChem. 17, 20, p. 1936-1944 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

    Cheng, J., Sahani, S., Hausrat, T. J., Yang, J., Ji, H., Schmarowski, N., Endle, H., Liu, X., Li, Y., Böttche, R., Radyushkin, K., Maric, H. M., Hoerder-Suabedissen, A., Molnár, Z., Prouvot, P., Trimbuch, T., Ninnemann, O., Huai, J., Fan, W., Visentin, B., Sabbadini, R., Strømgaard, Kristian, Stroh, A., Luhmann, H. J., Kneussel, M., Nitsch, R. & Vogt, J., 5 Oct 2016, In : Neuron. 92, 1, p. 126-142 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 in mouse models of pain, cognition and motor function

    Andreasen T., Jesper, Nasser, A., Caballero Puntiverio, Maitane, Sahlholt, M., Bach, Anders, Gynther, M., Strømgaard, Kristian & Pickering, Darryl S, 5 Jun 2016, In : European Journal of Pharmacology. 780, p. 166-73 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Ligand binding to the PDZ domains of postsynaptic density protein 95

    Toto, A., Pedersen, S. W., Karlsson, O. A., Moran, G. E., Andersson, E., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., May 2016, In : Protein Engineering Design and Selection (Print). 29, 5, p. 169-75 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter

    Rannversson, H., Andersen, J., Hall, L. S., Bang-Andersen, B., Park, M., Huber, T., Sakmar, T. P. & Strømgaard, Kristian, 19 Apr 2016, In : Nature Communications. 7, p. 1-9 9 p., 11261.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In : British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Design and synthesis of triazole-based peptidomimetics of a PSD-95 PDZ domain inhibitor

    Bach, Anders, Pedersen, T. B. & Strømgaard, Kristian, 2016, In : MedChemComm. 7, 3, p. 531-536 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Synthesis of symmetrical and non-symmetrical bivalent neurotransmitter ligands

    Stuhr-Hansen, N., Andersen, J., Thygesen, Mikkel Boas & Strømgaard, Kristian, 2016, In : ChemistrySelect. 1, 3, p. 407-413 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Total synthesis and structure–activity relationship studies of a series of selective G protein inhibitors

    Xiong, X., Zhang, H., Underwood, C. R., Harpsøe, Kasper, Gardella, T. J., Wöldike, M. F., Mannstadt, M., Gloriam, David E., Bräuner-Osborne, Hans & Strømgaard, Kristian, 2016, In : Nature Chemistry. 8, 11, p. 1035-1041 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2015
  32. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter

    Andersen, J., Ladefoged, L. K., Wang, Danyang, Kristensen, T. N. B., Bang-Andersen, B., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 18 Nov 2015, In : A C S Chemical Neuroscience. 6, 11, p. 1892-900 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation

    Rannversson, H., Wilson, P., Kristensen, K. B., Sinning, S., Kristensen, Anders Skov, Strømgaard, Kristian & Andersen, J., 5 Jun 2015, In : The Journal of Biological Chemistry. 290, 23, p. 14582-94 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95

    Strømgaard, Kristian, Bach, Anders & Nissen, K. B., 4 Jun 2015, IPC No. A61K38/17 , Patent No. WO2015/078477A1, Priority date 1 Dec 2013, Priority No. DK/2013/70735

    Research output: Patent

  35. Published

    Binding of ArgTX-636 in the NMDA receptor ion channel

    Poulsen, M. H., Andersen, J., Christensen, R., Hansen, K. B., Traynelis, S. F., Strømgaard, Kristian & Kristensen, Anders Skov, 16 Jan 2015, In : Journal of Molecular Biology. 427, 1, p. 176-89 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors

    Maric, H., Kasaragod, V. B., Kedström, L. M. H., Hausrat, T. J., Kneussel, M., Schindelin, H. & Strømgaard, Kristian, 7 Jan 2015, In : Angewandte Chemie (International ed. in English). 54, 2, p. 490-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1

    Wilbek, T. S., Skovgaard, T., Sorrell, F. J., Knapp, S., Berthelsen, J. & Strømgaard, Kristian, 2 Jan 2015, In : ChemBioChem. 16, 1, p. 59-63 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

    Andersen, J., Ringsted, K. B., Bang-Andersen, B., Strømgaard, Kristian & Kristensen, Anders Skov, 2015, In : Scientific Reports. 5, p. 1-12 12 p., 15650.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Design, Synthesis, and Characterization of Fatty Acid Derivatives of a Dimeric Peptide-Based Postsynaptic Density-95 (PSD-95) Inhibitor

    Nissen, K. B., Andersen, J. J., Haugaard-Kedström, L. M., Bach, Anders & Strømgaard, Kristian, 2015, In : Journal of Medicinal Chemistry. 58, p. 1575-1580 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Polyamine toxins from spiders and wasps: Polyamine toxins from spiders and wasps

    Xiong, X. & Strømgaard, Kristian, 2015, Polyamines: A Universal Molecular Nexus for Growth, Survival, and Specialized Metabolism. Springer, Japan, p. 201-214 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  41. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    Eildal, J. N. N., Bach, Anders, Dogan, J., Ye, F., Zhang, M., Jemth, P. & Strømgaard, Kristian, 2015, In : ChemBioChem. 16, p. 64–69 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family

    Nissen, K. B., Kedström, L. M. H., Wilbek, T. S., Nielsen, L. S., Åberg, E., Kristensen, Anders Skov, Bach, Anders, Jemth, P. & Strømgaard, Kristian, 2015, In : PLOS ONE. 10, 2, p. 1-17 17 p., e0117668.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2014
  44. Published

    Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin

    Maric, H., Kasaragod, V. B., Hausrat, T. J., Kneussel, M., Tretter, V., Strømgaard, Kristian & Schindelin, H., 22 Dec 2014, In : Nature Communications. 5, p. 1-11 11 p., 5767.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Structure–Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors

    Xiong, X., Poulsen, Mette Homann, Hussein, R. A., Nørager, N. G. & Strømgaard, Kristian, Dec 2014, In : ChemMedChem. 9, 12, p. 2661-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS

    Haugaard-Kedstrom, L. M., Albertsen, L., Gil, F. A., Ivarsson, Y., Strømgaard, Kristian & Kedström, L. M. H., Sep 2014, In : Journal of Peptide Science. 20, Suppl. 1, p. s39 1 p., YO11.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Mechanistic insight into benzenethiol catalyzed amide bond formations from thioesters and primary amines

    Stuhr-Hansen, N., Bork, N. & Strømgaard, Kristian, 14 Aug 2014, In : Organic & Biomolecular Chemistry. 12, 30, p. 5745-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors

    Nørager, N. G., Poulsen, Mette Homann, Jensen, A. G., Jeppesen, N. S., Kristensen, Anders Skov & Strømgaard, Kristian, 12 Jun 2014, In : Journal of Medicinal Chemistry. 57, 11, p. 4940-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (prozac)

    Andersen, J., Stuhr-Hansen, N., Dorvil, Linda Grønborg, Koldsø, H., Schiøtt, B., Strømgaard, Kristian & Kristensen, Anders Skov, May 2014, In : Molecular Pharmacology. 85, 5, p. 703-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites

    Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, 18 Apr 2014, In : ACS chemical biology. 9, 4, p. 935-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin

    Poulsen, Mette Homann, Lucas, S., Strømgaard, Kristian & Kristensen, Anders Skov, 22 Feb 2014, In : Neurochemical Research. 39, 10, p. 1906-1913 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Evaluation of PhTX-74 as Subtype-Selective Inhibitor of GluA2-Containing AMPA Receptors

    Poulsen, Mette Homann, Lucas, S., Strømgaard, Kristian & Kristensen, Anders Skov, Feb 2014, In : Molecular Pharmacology. 85, 2, p. 261-268 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins

    Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In : Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.

    Research output: Contribution to journalJournal articleResearch

  54. Published

    Facile synthesis of α-hydroxy carboxylic acids from the corresponding α-amino acids

    Stuhr-Hansen, N., Padrah, S. & Strømgaard, Kristian, 2014, In : Tetrahedron Letters. 55, 30, p. 4149-4151 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations

    Pedersen, S. W., Pedersen, S. B., Anker, L., Hultqvist, G., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2014, In : Nature Communications. 5, p. 1-11 11 p., 3215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    The role of backbone hydrogen bonds in the transition state for protein folding of a PDZ domain

    Pedersen, S. W., Hultqvist, G., Strømgaard, Kristian & Jemth, P., 2014, In : PLOS ONE. 9, 4, p. 1-7 7 p., e95619.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2013
  58. Published

    Design and synthesis of peptide YY analogues with c-terminal backbone amide-to-ester modifications

    Albertsen, L., Andersen, J. J., Paulsson, J. F., Thomsen, J. K., Norrild, J. C. & Strømgaard, Kristian, 12 Dec 2013, In : A C S Medicinal Chemistry Letters. 4, 12, p. 1228-1232 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Recombinant production of peptide C-terminal α-amides using an engineered intein

    Albertsen, L., Shaw, A. C., Norrild, J. C. & Strømgaard, Kristian, 20 Nov 2013, In : Bioconjugate Chemistry. 24, 11, p. 1883-94 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons

    Nørager, N. G., Jensen, C. B., Rathje, Mette, Andersen, J., Madsen, Kenneth Lindegaard, Kristensen, Anders Skov & Strømgaard, Kristian, 20 Sep 2013, In : A C S Chemical Biology. 8, 9, p. 2033-2041 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations

    Eildal, J. N. N., Hultqvist, G., Balle, T., Stuhr-Hansen, N., Padrah, S., Gianni, S., Strømgaard, Kristian & Jemth, P., 4 Sep 2013, In : Journal of the American Chemical Society. 135, 35, p. 12998-3007 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    A parallel semisynthetic approach for structure-activity relationship studies of peptide YY

    Albertsen, L., Østergaard, S., Paulsson, J. F., Norrild, J. C. & Strømgaard, Kristian, Sep 2013, In : ChemMedChem. 8, 9, p. 1505-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Preparation of peptide thioesters through fmoc-based solid-phase peptide synthesis by using amino thioesters

    Stuhr-Hansen, N., Wilbek, T. S. & Strømgaard, Kristian, 1 Aug 2013, In : European Journal of Organic Chemistry. 2013, 24, p. 5290-5294 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Energetic pathway sampling in a protein interaction domain

    Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In : Structure. 21, 7, p. 1193-1202

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Synthetic and mechanistic insight into nosylation of glycine residues

    Stuhr-Hansen, N., Sølling, Theis Ivan & Strømgaard, Kristian, 14 Apr 2013, In : Organic & Biomolecular Chemistry. 11, 14, p. 2288-2293 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy

    Fiorentini, M., Bach, Anders, Strømgaard, Kristian, Kastrup, Jette Sandholm Jensen & Gajhede, Michael, Apr 2013, In : Acta Crystallographica. Section D: Biological Crystallography. 69, Pt 4, p. 587-94 8 p.

    Research output: Contribution to journalJournal articleResearch

  67. Published

    UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, Jesper, Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In : Neuropharmacology. 67, p. 193-200 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors

    Poulsen, Mette Homann, Lucas, S., Bach, T. B., Barslund, A. F., Wenzler, C., Jensen, C. B., Kristensen, Anders Skov & Strømgaard, Kristian, 14 Feb 2013, In : Journal of Medicinal Chemistry. 56, 3, p. 1171-1181 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions

    Møller, Thor C., Wirth, V. F., Roberts, N. I., Bender, J., Bach, Anders, Jacky, B. P. S., Strømgaard, Kristian, Deussing, J. M., Schwartz, Thue W. & Martinez, Karen Laurence, 2013, In : PLOS ONE. 8, 5, e63352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group

    Pedersen, S. W., Armishaw, C. J. & Strømgaard, Kristian, 2013, Peptide synthesis and applications. Humana Press, Vol. 1047. p. 65-80 16 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  71. 2012
  72. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors

    Lucas, S., Poulsen, Mette Homann, Nørager, N. G., Barslund, A. F., Bach, T. B., Kristensen, Anders Skov & Strømgaard, Kristian, 26 Nov 2012, In : Journal of Medicinal Chemistry. 55, 22, p. 10297-10301 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    An expanded view of the protein folding landscape of PDZ domains

    Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In : Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    A heteromeric snake toxin and the molecular details of pain perception

    Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In : Angewandte Chemie International Edition. 51, 17, p. 4009-4011

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains

    Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In : Journal of the American Chemical Society. 134, 1, p. 599-605

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Submitted
  78. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In : The Journal of Biological Chemistry. 287, 52, p. 43694-43707 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

    Sørensen, L., Andersen, J., Thomsen, M., Hansen, S. M. R., Zhao, X., Sandelin, Albin Gustav, Strømgaard, Kristian & Kristensen, Anders Skov, 2012, In : Journal of Biological Chemistry. 287, p. 43694-43707 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Ligand binding by PDZ domains

    Chi, C. N., Bach, Anders, Strømgaard, Kristian, Gianni, S. & Jemth, P., 2012, In : BioFactors. 38, 5, p. 338-348 (Review) 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1302559