Majid Sheykhzade

Majid Sheykhzade

Associate Professor


  1. 2019
  2. E-pub ahead of print
  3. E-pub ahead of print

    Vascular pathology of large cerebral arteries in experimental subarachnoid hemorrhage : Vasoconstriction, functional CGRP depletion and maintained CGRP sensitivity. / Johansson, Sara Ellinor; Abdolalizadeh, Bahareh; Sheykhzade, Majid; Edvinsson, Lars; Sams, Anette.

    In: European Journal of Pharmacology, 14.01.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Submitted

    EFFECTS OF CALCITONIN GENE-RELATED PEPTIDE ON THE ARTERIAL VASODILATION IN THE EYE AND IMPLICATIONS FOR RETINAL FUNCTION. / Haanes, K. A.; Fedulov, V.; Blixt, F. W.; Sheykhzade, M.; Warfvinge, K.; Edvinsson, L.

    In: Cephalalgia, Vol. 38, 2019.

    Research output: Contribution to journalJournal articleResearch

  5. 2018
  6. Published

    POTASSIUM ACTIVATES THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AND DOES NOT IMPROVE ENDOTHELIAL FUNCTION IN HEALTHY NORMOTENSIVE MEN. / Dreier, Rasmus; Andersen, Ulrik; Egfjord, Martin; Sheykhzade, Majid; Jeppesen, Jorgen.

    In: Nephrology Dialysis Transplantation, Vol. 33, No. suppl_1, FO031, 18.05.2018, p. i31.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  7. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles. / Jensen, Ditte Marie; Christophersen, Daniel Vest; Sheykhzade, Majid; Skovsted, Gry Freja; Lykkesfeldt, Jens; Münter, Rasmus; Roursgaard, Martin; Loft, Steffen; Møller, Peter.

    In: Particle and Fibre Toxicology, Vol. 15, 12, 26.02.2018, p. 1-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Fmoc Solid-Phase Synthesis of Human a-Calcitonin Gene- Related Peptide and Two Carboxyfluorescein-labeled Analogs. / Ahmed, L. Sabbah; Abdolalizadeh, Bahareh; Sheykhzade, Majid; Hansen, Paul Robert.

    2018. Poster session presented at Gordon Conference on Peptides, Ventura, CA, USA February 11-16, 2018., .

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    CGRP and PACAP induced vasodilation in the porcine retinal vasculature. / Haanes, Kristian Agmund; Blixt, Frank W; Fedulov, Vadim; Sheykhzade, Majid; Sørensen, Karina D; Edvinsson, Lars.

    2018. 2643.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published

    Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion. / Kristiansen, Sarah Brøgger; Skovsted, Gry Freja; Berchtold, Lukas Adrian; Radziwon-Balicka, Aneta; Dreisig, Karin; Edvinsson, Lars; Sheykhzade, Majid; Haanes, Kristian Agmund.

    In: Scandinavian Cardiovascular Journal, Vol. 52, No. 6, 2018, p. 340-343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX. / Sheykhzade, Majid; Abdolalizadeh, Bahareh; Koole, Cassandra; Pickering, Darryl S; Dreisig, Karin; Johansson, Sara Ellinor; Abboud, Balsam Kadri; Dreier, Rasmus; Berg, Jais Oliver; Jeppesen, Jørgen Lykke; Sexton, Patrick; Edvinsson, Lars; Wootten, Denise; Sams, Anette.

    In: European Journal of Pharmacology, Vol. 829, 2018, p. 85-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide. / Jensen, Ditte Marie; Skovsted, Gry Freja; Lykkesfeldt, Jens; Dreier, Rasmus; Berg, Jais Oliver; Jeppesen, Jørgen Lykke; Sheykhzade, Majid; Loft, Steffen; Møller, Peter.

    In: Food and Chemical Toxicology, Vol. 120, 2018, p. 321-327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2017
  14. Published

    Differential inhibitory response to telcagepant on αCGRP induced vasorelaxation and intracellular Ca2+ levels in the perfused and non-perfused isolated rat middle cerebral artery. / Erdling, André; Sheykhzade, Majid; Edvinsson, Lars.

    In: Journal of Headache and Pain, Vol. 18, 61, 12.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Changes in vasodilation following myocardial ischemia/reperfusion in rats. / Kristiansen, Sarah Brøgger; Sheykhzade, Majid; Edvinsson, Lars; Haanes, Kristian Agmund.

    In: Nitric Oxide: Biology and Chemistry, Vol. 70, 11.2017, p. 68-75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Endothelin receptor mediated Ca(2+) signaling in coronary arteries after experimentally induced ischemia/reperfusion injury in rat. / Kristiansen, Sarah Brøgger; Haanes, Kristian A.; Sheykhzade, Majid; Edvinsson, Lars.

    In: Journal of Molecular and Cellular Cardiology, Vol. 111, 10.2017, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Calcium-handling of Endothelin A and B Receptors in Coronary Artery upon Post Ischemic Reperfusion Injury in Rats. / Kristiansen, Sarah Brøgger; Haanes, Kristian Agmund; Sheykhzade, Majid; Edvinsson, Lars.

    In: F A S E B Journal, Vol. 31, No. 1_supplement, lb505, 04.2017.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  18. Published

    Lipopolysaccharides, but not Angiotensin ll, lnduces Direct Pro‐lnflammatory Effects in Cultured Mouse Arteries and Human Endothelial and Vascular Smooth Muscle Cells. / Outzen, Emilie M; Zaki, Marina; Mehryar, Rahila; Abdolalizadeh, Bahareh; Sajid, Waseem; Boonen, Harrie C M; Sams, Anette; Sheykhzade, Majid.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 120, No. 4, 04.2017, p. 335-347.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Binding and functional pharmacological characteristics of gepant-type antagonists in rat brain and mesenteric arteries. / Sheykhzade, Majid; Amandi, Nilofar; Pla, Monica Vidal; Abdolalizadeh, Bahareh; Sams, Anette; Warfvinge, Karin; Edvinsson, Lars; Pickering, Darryl S.

    In: Vascular Pharmacology, Vol. 90, 10.02.2017, p. 36-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effect of PGD2 on middle meningeal artery and mRNA expression profile of L-PGD2 synthase and DP receptors in trigeminovascular system and other pain processing structures in rat brain. / Sekeroglu, Aysegül; Jacobsen, Julie Mie; Jansen-Olesen, Inger; Gupta, Saurabh; Sheykhzade, Majid; Olesen, Jes; Bhatt, Deepak K.

    In: Pharmacological Reports, Vol. 69, No. 1, 01.02.2017, p. 50-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Mechanical and vasomotor properties of piglet isolated middle cerebral artery. / Eriksen, Vibeke R.; Abdolalizadeh, Bahareh; Trautner, Simon; Greisen, Gorm; Sheykhzade, Majid.

    In: Pharmacology Research & Perspectives, Vol. 5, No. 1, e00279, 02.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2016
  23. Published

    Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation. / Kirchhoff, Jeppe Egedal; Diness, Jonas Goldin; Abildgaard, Lea; Sheykhzade, Majid; Grunnet, Morten; Jespersen, Thomas.

    In: Pfluegers Archiv, Vol. 468, No. 11, 08.10.2016, p. 1853–1863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inflammation and Vascular Effects after Repeated Intratracheal Instillations of Carbon Black and Lipopolysaccharide. / Christophersen, Daniel Vest; Jacobsen, Nicklas Raun; Jensen, Ditte Marie; Kermanizadeh, Ali; Sheykhzade, Majid; Loft, Steffen; Vogel, Ulla; Wallin, Håkan; Møller, Peter.

    In: P L o S One, Vol. 11, No. 8, e0160731, 29.08.2016, p. 1-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat. / Spray, Stine; Rasmussen, Marianne N P; Skovsted, Gry F; Warfvinge, Karin; Sheykhzade, Majid; Edvinsson, Lars.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 119, No. 1, 06.2016, p. 68-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Increased Contractile Response to Noradrenaline Induced By Factors Associated with the Metabolic Syndrome in Cultured Small Mesenteric Arteries. / Blædel, Martin; Sams, Anette; Boonen, Harrie C M; Sheykhzade, Majid.

    In: Pharmacology, Vol. 97, No. 1-2, 2016, p. 48-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2015
  28. Published

    Translational value of mechanical and vasomotor properties of mouse isolated mesenteric resistance-sized arteries. / Outzen, Emilie Middelbo; Zaki, Marina ; Abdolalizadeh, Bahareh; Nielsen, Anette Sams; Boonen, Harrie C.M.; Sheykhzade, Majid.

    In: Pharmacology Research & Perspectives, Vol. 3, No. 6, e00200, 22.12.2015, p. 1-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Altered stiffness in coronary arteries and effect of pirfenidone on endothelium-dependent vasodilatation in type 2 diabetic (db/db) mice. / Beck, Lilliana; Carlsson, Rune; Hernanz, Raquel; Sheykhzade, Majid; Simonsen, Ulf.

    In: Acta Physiologica (Print), Vol. 215, 09.2015, p. 48-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Calcium signaling in coronary artery after reperfusion damage in rat model of acute myocardial infarct. / Kristiansen, Sarah Brogger; Skovsted, Gry Freja; Sheykhzade, Majid; Edvinsson, Lars.

    In: Acta Physiologica (Print), Vol. 215, No. Supplement, 7, 09.2015, p. 3-4.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Biophysical characterization of KV3.1 potassium channel activating compounds. / Taskin, Bahar; von Schoubye, Nadia Lybøl; Sheykhzade, Majid; Bastlund, Jesper Frank; Grunnet, Morten; Jespersen, Thomas.

    In: European Journal of Pharmacology, Vol. 758, 05.07.2015, p. 164-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart. / Diness, Jonas Goldin; Kirchhoff, Jeppe Egedal; Sheykhzade, Majid; Jespersen, Thomas; Grunnet, Morten.

    In: Journal of Cardiovascular Pharmacology, Vol. 66, No. 3, 08.05.2015, p. 294–299.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    mRNA expression profile of prostaglandin D2 receptors in rat trigeminovascular system, and effect of prostaglandins in rat migraine models. / Sekeroglu, A.; Jansen-Olesen, I.; Gupta, S.; Sheykhzade, M.; Bhatt, D.

    In: Cephalalgia, Vol. 35, No. suppl 6S, PO446, 05.2015, p. 232-233.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Hepatic oxidative stress, genotoxicity and vascular dysfunction in lean or obese zucker rats. / Løhr, Mille; Folkmann, Janne Kjærsgaard; Sheykhzade, Majid; Jensen, Lars Jørn; Kermanizadeh, Ali; Loft, Steffen; Møller, Peter.

    In: PLOS ONE, Vol. 10, No. 3, e0118773, 04.03.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Functional and Molecular Evidence for Kv7 Channel Subtypes in Human Detrusor from Patients with and without Bladder Outflow Obstruction. / Svalø, Julie; Sheykhzade, Majid; Nordling, Jørgen; Matras, Christina; Bouchelouche, Pierre.

    In: PLOS ONE, Vol. 10, No. 2, e0117350, 19.02.2015, p. 1-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation. / Kirchhoff, Jeppe Egedal; Goldin Diness, Jonas; Sheykhzade, Majid; Grunnet, Morten; Jespersen, Thomas.

    In: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 12, No. 2, 02.2015, p. 409-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Solid-Phase Peptide Synthesis of Human alfa-Calcitonin Gene-Related Peptide and Two Fluorescent Analogs. / Fuente-Moreno, Marina; Oddo, Alberto; Sheykhzade, Majid; Pickering, Darryl S; Hansen, Paul Robert.

    Proceedings of the 24th American Peptide Symposium . 2015.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  38. 2014
  39. Published

    Genetic fuzzy system predicting contractile reactivity patterns of small arteries. / Tang, J; Sheykhzade, Majid; Clausen, B F; Boonen, H C M.

    In: C P T: Pharmacometrics & Systems Pharmacology, Vol. 3, No. 4, 02.04.2014, p. 1-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries. / Edvinsson, L; Ahnstedt, H; Larsen, R; Sheykhzade, Majid.

    In: Acta Physiologica (Print), Vol. 210, No. 4, 04.2014, p. 811-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion. / Skovsted, Gry Freja; Kruse, L.S.; Larsen, R; Pedersen, A F; Trautner, S; Sheykhzade, Majid; Edvinsson, L.

    In: British Journal of Pharmacology, Vol. 171, No. 11, 28.01.2014, p. 2726-2738.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Potentiated adrenomedullin-induced vasorelaxation during hypoxia in organ cultured porcine coronary arteries. / Hasbak, Philip; Sheykhzade, Majid; Schifter, Søren; Edvinsson, Lars.

    In: Journal of Cardiovascular Pharmacology, Vol. 63, No. 1, 01.2014, p. 58-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Endothelin ETB receptor upregulation, intracellular Ca2+ handling and ERK1/2 activation after myocardial ischemia-reperfusion damage. / Kristiansen, Sarah Brøgger; Skovsted, Gry Freja; Edvinsson, Lars; Sheykhzade, Majid.

    In: Journal of Vascular Research, Vol. 51, No. suppl. 2, 2014, p. 111.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs. / Boonen, Harrie C.M.; Moesgaard, Sophia Gry; Birck, Malene Muusfeldt; Christoffersen, Berit Østergaard; Cirera Salicio, Susanna; Heegaard, Peter M. H.; Højbøge, Tina Rødgaard; Jensen, Lars Jørn; Mortensen, Alan; Olsen, Lisbeth Høier; Sheykhzade, Majid; Tang, Jiaowei; Lykkesfeldt, Jens.

    In: Pflügers ARchiv (European Journal of Physiology), Vol. 466, No. 12, 2014, p. 2167-2176.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2013
  46. Published

    Permanent Distal Occlusion of Middle Cerebral Artery in Rat Causes Local Increased ETB, 5-HT1B and AT1 Receptor-Mediated Contractility Downstream of Occlusion. / Rasmussen, Marianne N P; Hornbak, Malene; Larsen, Stine S; Sheykhzade, Majid; Edvinsson, Lars.

    In: Journal of Vascular Research, Vol. 50, No. 5, 29.08.2013, p. 396-409.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation. / Outzen, Emilie Middelbo; Mehryar, Rahila; Boonen, Harrie C.M.; Nielsen, Anette Sams; Sheykhzade, Majid.

    2013. Poster session presented at DRA Summer School 2013, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  48. Published

    Bladder contractility is modulated by Kv7 channels in pig detrusor. / Svalø, Julie; Bille, Michala; Parameswaran Theepakaran, Neeraja; Sheykhzade, Majid; Nordling, Jørgen; Bouchelouche, Pierre.

    In: European Journal of Pharmacology, Vol. 715, No. 1-3, 21.05.2013, p. 312-320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    VIP/PACAP receptors in cerebral arteries of rat : characterization, localization and relation to intracellular calcium. / Erdling, André; Sheykhzade, Majid; Maddahi, Aida; Bari, Ferenc; Edvinsson, Lars.

    In: Neuropeptides, Vol. 47, No. 2, 01.02.2013, p. 85-92.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Calcium activity of upper thoracic dorsal root ganglion neurons in zucker diabetic Fatty rats. / Ghorbani, Marie Louise; Nyborg, Niels C B; Fjalland, Bjarne; Sheykhzade, Majid.

    In: International Journal of Endocrinology, Vol. 2013, 2013, p. Article ID 532850.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2012
  52. Published

    Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in apoE(-/-)mice. / Vesterdal, Lise K; Jantzen, Kim; Sheykhzade, Majid; Roursgaard, Martin; Folkmann, Janne K; Loft, Steffen; Møller, Peter.

    In: Nanotoxicology, Vol. 8, No. 1, 14.11.2012, p. 61-71.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Pharmacokinetics of pioglitazone, a thiazolidinedione derivative, in male Naeini (Iranian fat-tailed) sheep. / Ghoreishi, Sayed Mehdi; Rajaian, H.; Sheykhzade, Majid; Alikhani, M.; Rahmani, H. R. ; Hajipour , A. R.; Khorvash, M. ; Khodaei, H.R. .

    In: Journal of Applied Animal Research, Vol. 40, No. 3, 09.2012, p. 208-214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Effect of Ageing on the Passive and Active Tension and Pharmacodynamic Characteristics of Rat Coronary Arteries : Age-Dependent Increase in Sensitivity to 5-HT and K+. / Sheykhzade, Majid; Simonsen, Anja Hviid ; Boonen, Harrie C.M.; Outzen, Emilie Middelbo; Nyborg, Niels Chresten Berg.

    In: Pharmacology, Vol. 90, No. 3-4, 22.08.2012, p. 160-168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Inflammation as accelerator of type 2 diabetes and cardiovascular disease progression : the role of innate immunity (LPS) in vascular and pancreatic islet dysfunction. / Outzen, Emilie Middelbo; Sheykhzade, Majid; Nielsen, Anette Sams; Boonen, Harrie C.M.

    2012. Poster session presented at Danish Cardiovascular Research Academy 2012 summer meeting at the Sandbjerg Estate , Sønderborg, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  56. Published

    Kv 7 Positive Modulators Reduce Detrusor Overactivity and Increase Bladder Capacity in Rats. / Svalø, Julie; Hansen, Henrik H; Rønn, Lars Christian B; Sheykhzade, Majid; Munro, Gordon; Rode, Frederik; Jakobsen, Julie Svalø.

    In: Basic & Clinical Pharmacology & Toxicology Online, Vol. 110, No. 2, 02.2012, p. 145-153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Carbon black nanoparticles and vascular dysfunction in cultured endothelial cells and artery segments. / Vesterdal, Lise K; Mikkelsen, Lone; Folkmann, Janne K; Sheykhzade, Majid; Cao, Yi; Roursgaard, Martin; Loft, Steffen; Møller, Peter.

    In: Toxicology Letters, Vol. 214, No. 1, 2012, p. 19-26.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Early Onset Inflammation in Pre-Insulin-Resistant Diet-Induced Obese Rats Does Not Affect the Vasoreactivity of Isolated Small Mesenteric Arteries. / Blædel, Martin; Raun, Kirsten; Boonen, Harrie C M; Sheykhzade, Majid; Sams, Anette.

    In: Pharmacology, Vol. 90, No. 3-4, 2012, p. 125-132.

    Research output: Contribution to journalJournal articleResearchpeer-review

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