Michael Gajhede

Michael Gajhede

Professor


  1. Published

    Increased amylosucrase activity and specificity, and identification of regions important for activity, specificity and stability through molecular evolution. / van der Veen, Bart A; Skov, Lars K; Potocki-Véronèse, Gabrielle; Gajhede, Michael; Monsan, Pierre; Remaud-Simeon, Magali.

    In: F E B S Journal, Vol. 273, No. 4, 2006, p. 673-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structure and binding properties of a cameloid nanobody raised against KDM5B. / Wiuf, Anders; Kristensen, Line Hyltoft; Kristensen, Ole; Dorosz, Jerzy; Jensen, Jonas; Gajhede, Michael.

    In: Acta crystallographica. Section F, Structural biology communications, Vol. 71, No. Pt 10, 23.09.2015, p. 1235-1241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus. / Wang, Xiaole; Hald, Helle; Ernst, Heidi Asschenfeldt; Egebjerg, Jan; Christensen, Kenneth V; Gajhede, Michael; Kastrup, Jette Sandholm; Mirza, Osman Asghar.

    In: Protein Expression and Purification, Vol. 71, No. 2, 2010, p. 179-183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A tetrazolyl-substituted subtype-selective AMPA receptor agonist. / Vogensen, Stine Byskov; Frydenvang, Karla Andrea; Greenwood, Jeremy R.; Postorino, Giovanna; Nielsen, Birgitte; Pickering, Darryl Scott; Ebert, Bjarke; Bølcho, Ulrik; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov; Clausen, Rasmus Prætorius; Krogsgaard-Larsen, Povl.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 10, 2007, p. 2408-2414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure. / Vestergaard, Bente; Sanyal, Suparna; Roessle, Manfred; Mora, Liliana; Buckingham, Richard; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Svergun, Dmitri I; Ehrenberg, Måns.

    In: Molecular Cell, Vol. 20, 2005, p. 929-938.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils. / Vestergaard, Bente; Jensen, Minna Grønning; Roessle, Manfred; Kastrup, Jette Sandholm Jensen; Van De Weert, Marco; Flink, James M.; Frøkjær, Sven; Gajhede, Michael; Svergun, Dmitri I.

    In: PLoS - Biology, Vol. 5, No. 5, 2007, p. 1089-1097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. / Venskutonyte, Raminta; Frydenvang, Karla; Gajhede, Michael; Bunch, Lennart; Pickering, Darryl S; Kastrup, Jette Sandholm.

    In: Journal of Structural Biology, Vol. 176, No. 3, 12.2011, p. 307-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Kainate induces various domain closures in AMPA and kainate receptors. / Venskutonyte, Raminta; Frydenvang, Karla; Hald, Helle; Rabassa, Anna Ceravalls de; Gajhede, Michael; Ahring, Philip K.; Kastrup, Jette Sandholm.

    In: Neurochemistry International, Vol. 61, No. 4, 09.2012, p. 536-545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain. / Venskutonyte, Raminta; Larsen, Anja Probst; Frydenvang, Karla Andrea; Gajhede, Michael; Gefflaut, Thierry; Pickering, Darryl S; Bunch, Lennart; Kastrup, Jette Sandholm Jensen.

    In: ChemMedChem, Vol. 9, No. 10, 2014, p. 2254-2259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Synthesis, pharmacology and biostructural characterization of novel a4ß2 nicotinic acetylcholine receptor agonists. / Ussing, Christine A.; Hansen, Camilla Petrycer; Petersen, Jette Gellert; Jensen, Anders A.; Rohde, Line A.H. ; Ahring, Philip K.; Nielsen, Elisabeth Ø. ; Kastrup, Jette Sandholm; Gajhede, Michael; Frølund, Bente; Balle, Thomas.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 3, 2013, p. 940-951.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region. / Tapken, Daniel; Steffensen, Thomas Bielefeldt; Leth, Rasmus; Kristensen, Lise Baadsgaard; Gerbola, Alexander; Gajhede, Michael; Jørgensen, Flemming Steen; Olsen, Lars; Kastrup, Jette Sandholm.

    In: Scientific Reports, Vol. 7, 46145, 07.04.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cyclic lipoundecapeptide amphisin from Pseudomonas sp. strain DSS73. / Sørensen, Dan; Nielsen, Tommy H.; Christophersen, Carsten; Sørensen, Jan; Gajhede, Michael.

    In: Acta Crystallographica Section C, No. Vol. C57, 2001, p. 1123-1124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis. / Sprogøe, Desiree; van den Broek, Lambertus A M; Mirza, Osman; Kastrup, Jette Sandholm Jensen; Voragen, Alphons G J; Gajhede, Michael; Skov, Lars.

    In: Biochemistry, Vol. 43, No. 5, 10.02.2004, p. 1156-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. / Spangfort, Michael D; Mirza, Osman; Ipsen, Henrik; Van Neerven, R J Joost; Gajhede, Michael; Larsen, Jørgen.

    In: Journal of Immunology, Vol. 171, No. 6, 2003, p. 3084-90.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment. / Spangfort, M D; Mirza, Osman Asghar; Gajhede, M.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 55, No. Pt 12, 12.1999, p. 2035-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose. / Skov, Lars K.; Mirza, Osman; Sprogøe, Desiree; van der Veen, Bart; Remaud-Simeon, Magali; Albenne, Cecile; Monsan, Pierre; Gajhede, Michael.

    In: Biocatalysis and Biotransformation, Vol. 24, No. 1-2, 01.01.2006, p. 99-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structure of recombinant Ves v 2 at 2.0 Angstrom resolution : structural analysis of an allergenic hyaluronidase from wasp venom. / Skov, Lars K; Seppälä, Ulla; Coen, Jeremy J F; Crickmore, Neil; King, Te P; Monsalve, Rafael; Kastrup, Jette S; Spangfort, Michael D; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 62, No. Pt 6, 2006, p. 595-604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology. / Skov, Lars K; Pizzut-Serin, Sandra; Remaud-Simeon, Magali; Ernst, Heidi A; Gajhede, Michael; Mirza, Osman Asghar.

    In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online, Vol. 69, No. Pt 9, 09.2013, p. 973-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity. / Skov, Lars K; Mirza, Osman Asghar; Sprogøe, Desiree; Dar, Imran; Remaud-Simeon, Magali; Albenne, Cecile; Monsan, Pierre; Gajhede, Michael.

    In: Journal of Biological Chemistry, Vol. 277, No. 49, 06.12.2002, p. 47741-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family. / Skov, L K; Mirza, Osman Asghar; Henriksen, A; De Montalk, G P; Remaud-Simeon, M; Sarçabal, P; Willemot, R M; Monsan, P; Gajhede, M.

    In: Journal of Biological Chemistry, Vol. 276, No. 27, 06.07.2001, p. 25273-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Crystallization and preliminary X-ray studies of recombinant amylosucrase from Neisseria polysaccharea. / Skov, L K; Mirza, Osman Asghar; Henriksen, A; Potocki de Montalk, G; Remaud-Simeon, M; Sarcabal, P; Willemot, R M; Monsan, P; Gajhede, M.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 56, No. Pt 2, 02.2000, p. 203-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Snegleprotein øger forståelsen af vigtige receptorer i hjernen. / Shahsavar, Azadeh; Nielsen, Elsebeth Ø.; Kristensen, Jesper Langgaard; Gajhede, Michael; Balle, Thomas; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, Vol. 2012, 2012, p. 48-50.

    Research output: Contribution to journalJournal articleCommunication

  23. Published

    Structural Studies of Nicotinic Acetylcholine Receptors : Using Acetylcholine Binding Protein as a Structural Surrogate. / Shahsavar, Azadeh; Gajhede, Michael; Kastrup, Jette S; Balle, Thomas.

    In: Basic & Clinical Pharmacology & Toxicology Online, Vol. 118, No. 6, 17.11.2015, p. 399–407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHßE Suggests a Unique Mode of Antagonism. / Shahsavar, Azadeh; Kastrup, Jette S; Nielsen, Elsebet Ø.; Kristensen, Jesper L; Gajhede, Michael; Balle, Thomas.

    In: P L o S One, Vol. 7, No. 8, 2012, p. e40757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Acetylcholine-Binding Protein Engineered to Mimic the α4-α4 Binding Pocket in α4β2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity. / Shahsavar, Azadeh; Ahring, Philip K; Olsen, Jeppe A; Krintel, Christian; Kastrup, Jette S; Balle, Thomas; Gajhede, Michael.

    In: Molecular Pharmacology, Vol. 88, No. 4, 10.2015, p. 697-707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype. / Røder, Gustav; Blicher, Thomas; Justesen, Sune; Johannesen, Birthe; Kristensen, Ole; Kastrup, Jette; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 62, No. Pt 11, 2006, p. 1300-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501. / Røder, Gustav; Kristensen, Ole; Kastrup, Jette S; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 64, No. Pt 6, 2008, p. 459-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    High resolution crystal structures of the p120 RasGAP SH3 domain. / Ross, Birthe; Kristensen, Ole; Favre, Dimitri; Walicki, Joël; Kastrup, Jette Sandholm Jensen; Widmann, Christian; Gajhede, Michael.

    In: Biochemical and Biophysical Research Communications, Vol. 353, No. 2, 2007, p. 463-468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Få kræftcellen til at begå selvmord : en strukturel vinkel på kræft. / Ross, Birthe; Borchorst, Morten; Gajhede, Michael; Kristensen, Ole.

    In: Lægemiddelforskning, 2007, p. 22-23.

    Research output: Contribution to journalJournal articleCommunication

  30. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors : Unique role of halogen bonding revealed. / Rohde, Line Aagot Hede; Ahring, Philip Kiær; Jensen, Marianne Lerbech; Nielsen, Elsebet Østergaard; Peters, Dan; Helgstrand, Charlotte; Krintel, Christian; Harpsøe, Kasper; Gajhede, Michael; Kastrup, Jette Sandholm; Balle, Thomas.

    In: The Journal of Biological Chemistry, Vol. 287, No. 6, 03.02.2012, p. 4248-4259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping. / Rasmussen, Kim Krighaar; Kulahin, Nikolaj; Kristensen, Ole; Poulsen, Jens-Christian N; Sigurskjold, Bent W; Kastrup, Jette S; Berezin, Vladimir; Bock, Elisabeth; Walmod, Peter S; Gajhede, Michael.

    In: Journal of Molecular Biology, Vol. 382, No. 5, 2008, p. 1113-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR. / Prabhala, Bala K; Aduri, Nanda G; Iqbal, Mazhar; Rahman, Moazur; Gajhede, Michael; Hansen, Paul R; Mirza, Osman.

    In: Research in Microbiology, Vol. 168, No. 5, 16.02.2017, p. 443-449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells. / Prabhala, Bala K; Aduri, Nanda G; Sharma, Neha; Shaheen, Aqsa; Sharma, Arpan; Iqbal, Mazhar; Hansen, Paul R; Brasen, Christoffer; Gajhede, Michael; Rahman, Moazur; Mirza, Osman.

    In: The Journal of Biological Chemistry, Vol. 293, 2018, p. 1007-1017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network. / Petersson, Britt; Nielsen, Bettina Bryde; Rasmussen, Hanne; Larsen, Ingrid Kjøller; Gajhede, Michael; Nielsen, Peter E; Kastrup, Jette Sandholm Jensen.

    In: Journal of the American Chemical Society, Vol. 127, No. 5, 09.02.2005, p. 1424-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit. / Paës, Gabriel; Skov, Lars K; O'Donohue, Michael J; Rémond, Caroline; Kastrup, Jette Sandholm; Gajhede, Michael; Mirza, Osman.

    In: Biochemistry, Vol. 47, No. 28, 2008, p. 7441-7451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor. / Owczarek, Sylwia; Kiryushko, Darya; Hald Larsen, Marianne; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Sandi, Carmen; Berezin, Vladimir; Bock, Elisabeth; Soroka, Vladislav.

    In: The FASEB Journal, Vol. 24, No. 4, 2010, p. 1139-1150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification. / Ostergaard, L; Teilum, K; Mirza, O; Mattsson, O; Petersen, M; Welinder, K G; Mundy, J; Gajhede, M; Henriksen, A.

    In: Plant Molecular Biology, Vol. 44, No. 2, 2000, p. 231-43.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Hvad har varme at gøre med lægemidler? / Olsen, Lars; Kasper, Christina; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Jørgensen, Flemming Steen.

    In: Lægemiddelforskning, 2006, p. 31-33.

    Research output: Contribution to journalJournal articleCommunication

  39. Published

    Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors. / Olsen, Jeppe A.; Kastrup, Jette Sandholm Jensen; Peters, Dan; Gajhede, Michael; Balle, Thomas; Ahring, Philip K.

    In: Journal of Biological Chemistry, Vol. 288, No. 50, 13.12.2013, p. 35997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors. / Olsen, Jeppe A.; Balle, Thomas; Gajhede, Michael; Ahring, Philip K.; Kastrup, Jette Sandholm Jensen.

    In: PLOS ONE, Vol. 9, No. 3, 17.03.2014, p. e91232.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors. / Olsen, Jeppe A; Ahring, Philip K; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Balle, Thomas.

    In: The Journal of Biological Chemistry, Vol. 289, No. 36, 05.09.2014, p. 24911-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Differential Activity and Structure of Highly Similar Peroxidases. Spectroscopic, Crystallographic, and Enzymatic Analyses of Lignifying Arabidopsis thaliana Peroxidase A2 and Horseradish Peroxidase A2. / Nielsen, Kåre Lehmann; Indiani, Chiara; Henriksen, Anette; Feis, Alessandro; Becucci, Maurizio; Gajhede, Michael; Smulevich, Giuliette; Welinder, Karen G.

    In: Biochemistry, No. 40, 2001, p. 11013-11021.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP. / Nielsen, Bettina B; Pickering, Darryl S; Greenwood, Jeremy R; Brehm, Lotte; Gajhede, Michael; Schousboe, Arne; Kastrup, Jette S.

    In: FEBS Journal, Vol. 272, No. 7, 2005, p. 1639-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Identification of catechols as histone-lysine demethylase inhibitors. / Nielsen, Anders L; Kristensen, Line H; Stephansen, Karen B; Kristensen, Jan B L; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Helin, Kristian; Gajhede, Michael; Olsen, Lars.

    In: F E B S Letters, Vol. 586, No. 8, 2012, p. 1190-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Jagten på et signalstof til hjernens delta2-receptor. / Naur, Peter; Olsen, Lars; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, 2007, p. 32-33.

    Research output: Contribution to journalJournal articleCommunication

  46. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine. / Naur, Peter; Hansen, Kasper Bø; Kristensen, Anders Skov; Dravid, Shashank M.; Pickering, Darryl Scott; Olsen, Lars; Vestergaard, Bente; Egebjerg, Jan; Gajhede, Michael; Traynelis, Stephen F.; Kastrup, Jette Sandholm Jensen.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 104, No. 35, 2007, p. 14116-14121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate. / Naur, Peter; Vestergaard, Bente; Skov, Lars; Egebjerg, Jan ; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: FEBS letters, Vol. 579, 2005, p. 1154-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Arabidopsis thaliana peroxidase N : structure of a novel neutral peroxidase. / Mirza, Osman Asghar; Henriksen, A; Ostergaard, L; Welinder, K G; Gajhede, M.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 56, No. Pt 3, 03.2000, p. 372-5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Dominant epitopes and allergic cross-reactivity : complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. / Mirza, Osman Asghar; Henriksen, A; Ipsen, H; Larsen, J N; Wissenbach, M; Spangfort, M D; Gajhede, M.

    In: Journal of Immunology, Vol. 165, No. 1, 01.07.2000, p. 331-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose. / Mirza, Osman Asghar; Skov, L K; Remaud-Simeon, M; Potocki de Montalk, G; Albenne, C; Monsan, Pierre; Gajhede, Michael.

    In: Biochemistry, Vol. 40, No. 30, 31.07.2001, p. 9032-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion. / Mirza, Osman; Henriksen, Lars Skov; Sprogøe, Desiree; van den Broek, Lambertus A M; Beldman, Gerrit; Kastrup, Jette S; Gajhede, Michael.

    In: Journal of Biological Chemistry, Vol. 281, No. 46, 2006, p. 35576-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Crystal Structures of Amylosucrase from Neisseria polysaccharea in Complex with D-Glucose and the Active Site Mutant Glu328Gln in Complex with the Natural Substrate Sucrose. / Mirza, Osman; Skov, Lars Kobberø; Remaud-Simeon, Magali; Potocki de Montalk, Gabrielle; Albenne, Cecile; Monsan, Pierre; Gajhede, Michael.

    In: Biochemistry, No. 40, 2001, p. 9032-9039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1. / Meno, Kåre H; Kastrup, Jette S; Kuo, I-Chun; Chua, Kaw Yan; Gajhede, Michael.

    In: Allergy, Vol. 72, No. 4, 13111, 01.04.2017, p. 665-670.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The metal binding site of the major house dust mite allergen Der p 1. / Meno, Kåre; Thorsted, Peter B; Ipsen, Henrik; Kristensen, Ole; Larsen, Jørgen; Spangfort, Michael D; Gajhede, Michael; Lund, Kaare.

    In: Journal of Allergy and Clinical Immunology, Vol. 118, No. 4, 2006, p. 971.

    Research output: Contribution to journalComment/debateResearchpeer-review

  55. Published

    The crystal structure of recombinant proDer p 1, a major house dust mite proteolytic allergen. / Meno, Kåre; Thorsted, Peter B; Ipsen, Henrik; Kristensen, Ole; Larsen, Jørgen; Spangfort, Michael D; Gajhede, Michael; Lund, Kaare.

    In: Journal of Immunology, Vol. 175, No. 6, 2005, p. 3835-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Inhibitors of histone demethylases. / Lohse, Brian; Kristensen, Jesper L; Kristensen, Line H; Agger, Karl; Helin, Kristian; Gajhede, Michael; Clausen, Rasmus P.

    In: Bioorganic & Medicinal Chemistry, Vol. 19, No. 12, 01.02.2011, p. 3625-3636.

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors. / Lohse, Brian; Nielsen, Anders L; Kristensen, Jan B L; Helgstrand, Charlotte; Cloos, Paul Andreas Compare; Olsen, Lars; Gajhede, Michael; Clausen, Rasmus Prætorius; Kristensen, Jesper Langgaard.

    In: Angewandte Chemie International Edition, Vol. 50, No. 39, 19.09.2011, p. 9100-9103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. / Kvist, Trine; Steffensen, Thomas Bielefeldt; Greenwood, Jeremy R; Mehrzad Tabrizi, Fatemeh; Hansen, Kasper Bø; Gajhede, Michael; Pickering, Darryl S; Traynelis, Stephen F; Kastrup, Jette Sandholm; Bräuner-Osborne, Hans.

    In: The Journal of Biological Chemistry, Vol. 288, 2013, p. 33124-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published
    Crystal structure of NCAM2 IgIV-Fn3I. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Kastrup, Jette Sandholm Jensen (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2009.

    Research output: Non-textual formDatasetResearch

  60. Published

    Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1. / Kulahin, Nikolaj; Kasper, Christina; Kristensen, Ole; Kastrup, Jette Sandholm; Berezin, Vladimir; Bock, Elisabeth; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 61, No. Pt 9, 2005, p. 858-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published
    Crystal Structure of NCAM2 Ig1-2. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  62. Published
    Crystal Structure of NCAM2 Ig1 (I4122 Cell Unit). Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Kastrup, Jette Sandholm Jensen (Other); Poulsen, Jens-Christian Navarro (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  63. Published
    Crystal structure of NCAM2 IgIV-Fn3II. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Kastrup, Jette Sandholm Jensen (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2009. 17. November.

    Research output: Non-textual formDatasetResearch

  64. Published

    Structure of rat acidic fibroblast growth factor at 1.4 A resolution. / Kulahin, Nikolaj; Kiselyov, Vladislav; Kochoyan, Artur; Kristensen, Ole; Kastrup, Jette Sandholm Jensen; Berezin, Vladimir; Bock, Elisabeth Marianne; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 63, No. Pt2, 2007, p. 65-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Dimerization effect of sucrose octasulfate on rat FGF1. / Kulahin, Nikolaj; Kiselyov, Vladislav; Kochoyan, Artur; Kristensen, Ole; Kastrup, Jette Sandholm Jensen; Berezin, Vladimir; Bock, Elisabeth Marianne; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 64, No. Pt6, 2008, p. 448-452.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1. / Kulahin, Nikolaj; Kasper, Christina; Gajhede, Michael; Berezin, Vladimir; Bock, Elisabeth; Kastrup, Jette Sandholm Jensen.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 60, No. Pt 3, 03.2004, p. 591-3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published
    Crystal Structure of NCAM2 Ig2-3. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  68. Published

    Structural model and trans-interaction of the entire ectodomain of the olfactory cell adhesion molecule. / Kulahin, Nikolaj; Kristensen, Ole; Rasmussen, Kim K; Olsen, Lars; Rydberg, Patrik; Vestergaard, Bente; Kastrup, Jette Sandholm; Berezin, Vladimir; Bock, Elisabeth; Walmod, Peter Schledermann; Gajhede, Michael.

    In: Structure, Vol. 19, No. 2, 09.02.2011, p. 203-211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published
    Crystal Structure of NCAM2 Ig34. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  70. Published

    Chaperone binding at the ribosomal exit tunnel. / Kristensen, Ole; Gajhede, Michael.

    In: Structure, Vol. 11, No. 12, 2003, p. 1547-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Crystallization of a stringent response factor from Aquifex aeolicus. / Kristensen, Ole; Laurberg, Martin; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 58, No. Pt 7, 2002, p. 1198-200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp. / Kristensen, Ole; Ross, Birthe; Gajhede, Michael.

    In: Journal of Molecular Biology, Vol. 375, No. 5, 2008, p. 1469-1476.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    A unique set of SH3-SH3 interactions controls IB1 homodimerization. / Kristensen, Ole; Guenat, Sylvie; Dar, Imran; Allaman-Pillet, Nathalie; Abderrahmani, Amar; Ferdaoussi, Mourad; Roduit, Raphaël; Maurer, Fabienne; Beckmann, Jacques S; Kastrup, Jette S; Gajhede, Michael; Bonny, Christophe.

    In: E M B O Journal, Vol. 25, No. 4, 2006, p. 785-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family. / Kristensen, Ole; Laurberg, Martin; Liljas, Anders; Kastrup, Jette Sandholm Jensen; Gajhede, Michael.

    In: Biochemistry, Vol. 43, No. 28, 2004, p. 8894-900.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. / Kristensen, Line Hyltoft; Nielsen, Anders Laerke; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Kastrup, Jette Sandholm; Helin, Kristian; Olsen, Lars; Gajhede, Michael.

    In: F E B S Journal, Vol. 279, No. 11, 06.2012, p. 1905-1914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A : Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases. / Kristensen, Jan B L; Nielsen, Anders L; Jørgensen, Lars; Kristensen, Line Hyltoft; Helgstrand, Charlotte; Juknaite, Lina; Kristensen, Jesper Langgaard; Kastrup, Jette Sandholm; Clausen, Rasmus Prætorius; Olsen, Lars; Gajhede, Michael.

    In: F E B S Letters, Vol. 585, No. 12, 23.06.2011, p. 1951-1956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors. / Kristensen, Anders S; Hansen, Kasper B; Naur, Peter; Olsen, Lars; Kurtkaya, Natalie L; Dravid, Shashank M; Kvist, Trine; Yi, Feng; Pøhlsgaard, Jacob; Clausen, Rasmus P; Gajhede, Michael; Kastrup, Jette S; Traynelis, Stephen F.

    In: Molecular Pharmacology, Vol. 89, No. 2, 02.2016, p. 253-262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain. / Krintel, Christian; Frydenvang, Karla; Ceravalls de Rabassa, Anna; Kaern, Anne Mette; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette S.

    In: F E B S Journal, 27.03.2014, p. 2422–2430.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain. / Krintel, Christian; Harpsøe, Kasper; Zachariassen, Linda G; Peters, Dan; Frydenvang, Karla; Pickering, Darryl S; Gajhede, Michael; Kastrup, Jette S.

    In: Acta crystallographica. Section D, Biological crystallography, Vol. 69, No. Pt 9, 09.2013, p. 1645-52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. / Krintel, Christian; Frydenvang, Karla; Olsen, Lars; Kristensen, Maria T; de Barrios, Oriol; Naur, Peter; Francotte, Pierre; Pirotte, Bernard; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 173-178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209. / Kasper, Christina; Pickering, Darryl S; Mirza, Osman; Olsen, Lars; Kristensen, Anders S; Greenwood, Jeremy R; Liljefors, Tommy; Schousboe, Arne; Wätjen, Frank; Gajhede, Michael; Sigurskjold, Bent W; Kastrup, Jette S.

    In: Journal of Molecular Biology, Vol. 357, No. 4, 2006, p. 1184-201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 . / Kasper, Christina; Frydenvang, Karla Andrea; Naur, Peter; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: FEBS Letters, Vol. 582, No. 29, 2008, p. 4089-4094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites. / Kaae, Birgitte Høiriis; Harpsøe, Kasper; Kastrup, Jette Sandholm Jensen; Sanz, Alberto Contreras; Pickering, Darryl Scott; Metzler, Bjørn; Clausen, Rasmus Prætorius; Gajhede, Michael; Sauerberg, Per; Liljefors, Tommy; Madsen, Ulf.

    In: Chemistry & Biology, Vol. 14, No. 11, 2007, p. 1294-303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Cyclic Acetals. Structural Analysis of 1,3‐Dioxepine and Related Compounds. / Jørgensen, Flemming S.; Gajhede, Michael; Frei, Bruno.

    In: Helvetica Chimica Acta, Vol. 68, No. 8, 01.01.1985, p. 2148-2157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Conformational stability of calreticulin. / Jørgensen, Charlotte S; Trandum, Christa; Larsen, Nanna Brink; Ryder, L Rebekka; Gajhede, Michael; Skov, Lars; Højrup, Peter; Barkholt, Vibeke; Houen, Gunnar.

    In: Protein and Peptide Letters, Vol. 12, No. 7, 2005, p. 687-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution. / Jørgensen, Anders Dysted; Nøhr, Jane; Kastrup, Jette Sandholm; Gajhede, Michael; Sigurskjold, Bent Walther; Sauer, Jørgen; Svergun, Dmitri I.; Svensson, Birte; Vestergaard, Bente.

    In: Journal of Biological Chemistry, Vol. 283, No. 21, 2008, p. 14772-14780.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors. / Juknaite, Lina; Venskutonyte, Raminta; Assaf, Zeinab; Faure, Sophie; Gefflaut, Thierry; Aitken, David J.; Nielsen, Birgitte; Gajhede, Michael; Kastrup, Jette Sandholm Jensen; Bunch, Lennart; Frydenvang, Karla; Pickering, Darryl S.

    In: Journal of Structural Biology, Vol. 180, No. 1, 2012, p. 39-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes. / Jones, Sarah E.; Olsen, Lars; Dorosz, Jerzy; Seger, Signe T.; Andersson, Jan L.; Kristensen, Line H.; Gajhede, Michael.

    In: ChemBioChem, Vol. 19, No. 17, 04.09.2018, p. 1817-1822.

    Research output: Contribution to journalLetterResearchpeer-review

  89. Published

    Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. / Jones, Sarah E; Olsen, Lars; Gajhede, Michael.

    In: Biochemistry, Vol. 57, No. 5, 2018, p. 585–592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Structure of the house dust mite allergen Der f 2 : implications for function and molecular basis of IgE cross-reactivity. / Johannessen, Birthe R; Skov, Lars; Kastrup, Jette S; Kristensen, Ole; Bolwig, Caroline; Larsen, Jørgen; Spangfort, Michael; Lund, Kaare; Gajhede, Michael.

    In: F E B S Letters, Vol. 579, No. 5, 2005, p. 1208-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Gennembrud i forståelsen af insulinfibrillering. / Jensen, Minna Grønning; Vestergaard, Bente; Frøkjær, Sven; Gajhede, Michael; Flink, James M.; Van De Weert, Marco; Kastrup, Jette Sandholm Jensen; Svergun, Dmitri I.

    In: Lægemiddelforskning, 2007, p. 10-11.

    Research output: Contribution to journalJournal articleCommunication

  92. Published

    Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea. / Jensen, Malene H; Mirza, Osman Asghar; Albenne, Cecile; Remaud-Simeon, Magali; Monsan, Pierre; Gajhede, Michael; Skov, Lars.

    In: Biochemistry, Vol. 43, No. 11, 23.03.2004, p. 3104-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1. / Holm, Jens; Ferreras, Mercedes; Ipsen, Henrik; Würtzen, Peter A; Gajhede, Michael; Larsen, Jørgen N; Lund, Kaare; Spangfort, Michael D.

    In: Journal of Biological Chemistry, Vol. 286, No. 20, 20.05.2011, p. 17569-17578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Molecular basis of allergic cross-reactivity between group 1 major allergens from birch and apple. / Holm, J.; Bærentzen, G.; Gajhede, Michael; Ipsen, H.; Larsen, J. N.; Løwenstein, H.; Wissenbach, M.; Spangfort, M. D.

    In: Journal of Chromatography - B, Vol. 756, No. 1-2, 2001, p. 307-313.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase. / Henriksen, Annette; Aghajari, Nushin; Jensen, Kaj Frank; Gajhede, Michael.

    In: Biochemistry, Vol. 35, No. 12, 1996, p. 3803-3809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    The Structures of the Horseradish Peroxidase C-Ferulic Acid Complex and the Ternary Comples with Cyanide Suggest How Peroxidases Oxidize Small Phenolic Substrates. / Henriksen, Anette; Smith, Andrew T.; Gajhede, Michael.

    In: J. of Biol. Chem., No. 49, 1999, p. 35005-34011.

    Research output: Contribution to journalJournal articleResearch

  97. Published

    Cyclic lipoundecapeptide tensin from Pseudomonas fluorescens strain 96.578. / Henriksen, A. S.; Anthoni, Uffe; Nielsen, Tommy H.; Sørensen, Jan; Christophersen, Sven Carsten; Gajhede, Michael.

    In: Acta Crystallographica Section C, No. C56, 2000, p. 113-115.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Structural interactions between horseradish peroxidase C and the substrate benzhydroxamic acid determined by X-ray crystallography. / Henriksen, A.; Schuller, David J.; Meno, K.; Welinder, Karen G.; Smith, A.T.; Gajhede, Michael.

    In: Biochemistry, No. 37, 1998, p. 8054-8060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Structure of Barley Grain Peroxidase Refined at 1.9 A Resolution. A plant Peroxidase Reversibly Inactived at Neutral pH. / Henriksen, A.; Welinder, Karen G.; Gajhede, Michael.

    In: Journal of Biological Chemistry, No. 273, 1998, p. 2241-2248.

    Research output: Contribution to journalJournal articleResearch

  100. Published

    Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions. / Henriksen, A; Mirza, O; Indiani, C; Teilum, K; Smulevich, G; Welinder, K G; Gajhede, M.

    In: Protein Science, Vol. 10, No. 1, 2001, p. 108-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Major venom allergen of yellow jackets, Ves v 5 : structural characterization of a pathogenesis-related protein superfamily. / Henriksen, A; King, T P; Mirza, O; Monsalve, R I; Meno, K; Ipsen, H; Larsen, J N; Gajhede, Michael; Spangfort, M D.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 45, No. 4, 2001, p. 438-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Molecular determinants of subtype-selective efficacies of cytisine and the novel compound NS3861 at heteromeric nicotinic acetylcholine receptors. / Harpsøe, Kasper; Hald, Helle; Timmermann, Daniel B; Jensen, Marianne L; Dyhring, Tino; Nielsen, Elsebet Ø; Peters, Dan; Balle, Thomas; Gajhede, Michael; Kastrup, Jette Sandholm Jensen; Ahring, Philip K.

    In: Journal of Biological Chemistry, Vol. 288, No. 4, 25.01.2013, p. 2559-2570.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Modulation of the dimer interface at ionotropic glutamate-like receptor d2 by D-serine and extracellular calcium. / Hansen, Kasper Bø; Naur, Peter; Kurtkaya, Natalie L; Kristensen, Anders Skov; Gajhede, Michael; Kastrup, Jette Sandholm; Traynelis, Stephen F.

    In: Journal of Neuroscience, Vol. 29, No. 4, 2009, p. 907-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. / Hald, Helle; Ahring, Philip Kiær; Timmermann, Daniel Brunicardi; Liljefors, Tommy; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Journal of Molecular Biology, Vol. 391, No. 5, 2009, p. 906-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5 : Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. / Hald, Helle; Naur, Peter; Pickering, Darryl Scott; Sprogøe, Desiree; Madsen, Ulf; Timmermann, Daniel B.; Ahring, Philip K.; Liljefors, Tommy; Schousboe, Arne; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Journal of Biological Chemistry, Vol. 282, No. 35, 2007, p. 25726-25736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Structural mutations of C-domains in members of the Ig superfamily. Consequences for the interactions between the T cell antigen receptor and the zeta 2 homodimer. / Geisler, C; Rubin, B; Caspar-Bauguil, S; Champagne, E; Vangsted, A; Hou, X; Gajhede, M.

    In: Journal of Immunology, Vol. 148, No. 11, 1992, p. 3469-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Cobalt(III) Cage Complexes Linked to 4-Pyridyl: Models for Protein Modification. / Gajhede, Michael; Hammershøi, Anders; Skov, Lars Kobberøe.

    In: Dalton Transactions (Print Edition), Vol. 45, No. 5, 1991, p. 474-481.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Plant peroxidases: Substrate complexes with mechanistic implications. / Gajhede, Michael.

    In: Biochemical Society Transactions, No. 29, 2001, p. 91-99.

    Research output: Contribution to journalJournal articleResearch

  109. Published

    STRUCTURE OF 1-DIMETHYLAMINO-2,2,3,4,4-PENTAMETHYL-1-LAMBDA-5-PHOSPHETANE 1-SULFIDE, C10H22NPS, AT 105 K. / GAJHEDE, M; DAHL, O; Nielsen, John.

    In: Acta Crystallographica. Section C: Crystal Structure Communications, Vol. 41, No. JUN, 1985, p. 935-937.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine. / Frydenvang, Karla Andrea; Lash, L Leanne; Naur, Peter; Postila, Pekka A; Pickering, Darryl S; Smith, Caleb M; Gajhede, Michael; Sasaki, Makoto; Sakai, Ryuichi; Pentikäinen, Olli T; Swanson, Geoffrey T; Kastrup, Jette Sandholm.

    In: Journal of Biological Chemistry, Vol. 284, No. 21, 2009, p. 14219-14229.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    At være eller ikke være en antagonist. / Frydenvang, Karla Andrea; Naur, Peter; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, 2009, p. 43-45.

    Research output: Contribution to journalJournal articleCommunication

  112. Published

    Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2. / Frandsen, Anne; Pickering, Darryl S.; Vestergaard, Bente; Kasper, Christina; Nielsen, Bettina Bryde; Greenwood, Jeremy R; Campiani, Giuseppe; Fattorusso, Caterina; Gajhede, Michael; Schousboe, Arne; Kastrup, Jette Sandholm.

    In: Molecular Pharmacology, Vol. 67, No. 3, 2005, p. 703-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Structure of the first PDZ domain of human PSD-93. / Fiorentini, Monica; Nielsen, Ann Kallehauge; Kristensen, Ole; Kastrup, Jette Sandholm; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 65, No. 12, 2009, p. 1254-1257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy. / Fiorentini, Monica; Bach, Anders; Strømgaard, Kristian; Kastrup, Jette S; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 69, No. Pt 4, 04.2013, p. 587-94.

    Research output: Contribution to journalJournal articleResearch

  115. Published

    Chemical and thermal unfolding of calreticulin. / Duus, K.; Larsen, N.; Tran, T. A. T.; Güven, E.; Skov, L. K.; Jespersgaard, C; Gajhede, Michael; Houen, Gunnar.

    In: Protein and Peptide Letters, Vol. 20, 2013, p. 562-568.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B. / Dorosz, Jerzy; Kristensen, Line Hyltoft; Aduri, Nanda G; Mirza, Osman; Lousen, Rikke; Bucciarelli, Saskia; Mehta, Ved; Sellés-Baiget, Selene; Solbak, Sara Marie Øie; Bach, Anders; Mesa, Pablo; Hernandez, Pablo Alcon; Montoya, Guillermo; Nguyen, Tam T. T. N.; Rand, Kasper D.; Boesen, Thomas; Gajhede, Michael.

    In: Scientific Reports, Vol. 9, 4019, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Structure-Based Design of a New Scaffold for Cell-Penetrating Peptidic Inhibitors of the Histone Demethylase PHF8. / Dorosz, Jerzy; Olsen, Lars; Seger, Signe Teuber; Steinhauer, Cornelia; Bouras, Giorgos; Helgstrand, Charlotte; Wiuf, Anders; Gajhede, Michael.

    In: ChemBioChem, Vol. 18, No. 14, 18.07.2017, p. 1369-1375.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Role of CD3 gamma in T cell receptor assembly. / Dietrich, J; Neisig, A; Hou, X; Wegener, A M; Gajhede, M; Geisler, C.

    In: Journal of Cell Biology, Vol. 132, No. 3, 1996, p. 299-310.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Crystallization and preliminary crystallographic characterization of an SH3 domain from the IB1 scaffold protein. / Dar, Imran; Bonny, Christophe; Pedersen, Jan Torleif; Gajhede, Michael; Kristensen, Ole.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 59, No. Pt 12, 2003, p. 2300-2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue : synthesis, molecular pharmacology, and biostructural characterization. / Clausen, Rasmus Prætorius; Naur, Peter; Kristensen, Anders Skov; Greenwood, Jeremy R; Strange, Mette; Bräuner-Osborne, Hans; Jensen, Anders Asbjørn; Nielsen, Anne Sophie T; Geneser, Ulla; Ringgaard, Lone M; Nielsen, Birgitte; Pickering, Darryl S; Brehm, Lotte; Gajhede, Michael; Krogsgaard-Larsen, Povl; Kastrup, Jette Sandholm.

    In: Journal of Medicinal Chemistry, Vol. 52, No. 15, 2009, p. 4911-4922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    The apo structure of sucrose hydrolase from Xanthomonas campestris pv. campestris shows an open active-site groove. / Champion, Elise; Remaud-Simeon, Magali; Skov, Lars Kobberøe; Kastrup, Jette Sandholm; Gajhede, Michael; Mirza, Osman Asghar.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 65, No. 12, 2009, p. 1309-1314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Expression, purification and characterization of the human MTA2-RBBP7 complex. / Brasen, Christoffer; Dorosz, Jerzy; Wiuf, Anders; Boesen, Thomas; Mirza, Osman; Gajhede, Michael.

    In: Biochimica et biophysica acta, Vol. 1865, No. 5, 04.02.2017, p. 531-538.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. Published

    Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue. / Blicher, Thomas; Kastrup, Jette Sandholm; Pedersen, Lars Østergaard; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica Section F-Structural Biology and Crystallization Communications, Vol. 62, No. Pt 12, 2006, p. 1179-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide. / Blicher, Thomas; Kastrup, Jette Sandholm; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 61, No. Pt 8, 2005, p. 1031-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. / Beich-Frandsen, Mads; Pickering, Darryl S; Mirza, Osman; Johansen, Tommy N; Greenwood, Jeremy; Vestergaard, Bente; Schousboe, Arne; Gajhede, Michael; Liljefors, Tommy; Kastrup, Jette S.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 5, 2008, p. 1459-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function. / Backe, Marie Balslev; Andersson, Jan Legaard; Bacos, Karl; Christensen, Dan Ploug; Hansen, Jakob Bondo; Dorosz, Jerzy Jòzef; Gajhede, Michael; Dahlby, Tina; Bysani, Madhusudhan; Kristensen, Line Hyltoft; Ling, Charlotte; Olsen, Lars; Mandrup-Poulsen, Thomas.

    In: Molecular and Cellular Endocrinology, Vol. 460, 15.01.2018, p. 47-56.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage. / Bach, Anders*; Clausen, Bettina H; Møller, Magda; Vestergaard, Bente; Chi, Celestine N; Round, Adam; Sørensen, Pernille Louise; Nissen, Klaus Bertram; Kastrup, Jette Sandholm; Gajhede, Michael; Jemth, Per; Kristensen, Anders Skov; Lundström, Patrik; Lambertsen, Kate Lykke; Strømgaard, Kristian* (*Corresponding).

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, No. 9, 28.02.2012, p. 3317-3322.

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. / Assaf, Z.; Larsen, Anja Probst; Venskutonyte, Raminta; Han, Liwei; Abrahamsen, Bjarke; Nielsen, Birgitte; Gajhede, Michael; Kastrup, Jette Sandholm; Jensen, Anders A.; Pickering, Darryl S; Frydenvang, Karla ; Gefflaut, T; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 56, No. 4, 2013, p. 1614-1628.

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. Published

    Maltooligosaccharide disproportionation reaction : an intrinsic property of amylosucrase from Neisseria polysaccharea. / Albenne, Cécile; Skov, Lars K; Mirza, Osman Asghar; Gajhede, Michael; Potocki-Véronèse, Gabrielle; Monsan, Pierre; Remaud-Simeon, Magali.

    In: F E B S Letters, Vol. 527, No. 1-3, 11.09.2002, p. 67-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. Published

    Towards the molecular understanding of glycogen elongation by amylosucrase. / Albenne, Cécile; Skov, Lars K.; Tran, Vinh; Gajhede, Michael; Monsan, Pierre; Remaud-Siméon, Magali; André-Leroux, Gwénaëlle.

    In: Proteins - Structure Function and Bioinformatics, Vol. 66, No. 1, 2007, p. 118-126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Site-directed mutagenesis of key amino acids in the active site of amylosucrase from Neisseria polysaccharea. / Albenne, Cécile; Potocki De Montalk, Gabrielle; Monsan, Pierre; Skov, Lars; Mirza, Osman; Gajhede, Michael; Remaud-Simeon, Magali.

    In: Biologia - Section Cellular and Molecular Biology, Vol. 57, No. SUPPL. 11, 01.12.2002, p. 119-128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase. / Albenne, Cécile; Skov, Lars; Mirza, Osman Asghar; Gajhede, Michael; Feller, Georges; D'Amico, Salvino; André, Gwénaëlle; Potocki-Véronèse, Gabrielle; van der Veen, Bart A; Monsan, Pierre; Remaud-Simeon, Magali.

    In: Journal of Biological Chemistry, Vol. 279, No. 1, 02.01.2004, p. 726-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Rational and combinatorial engineering of the glucan synthesizing enzyme amylosucrase. / Albenne, C.; Van Der Veen, B.A.; Potocki-Véronèse, G.; Joucla, G.; Skov, L.; Mirza, Osman Asghar; Gajhede, M.; Monsan, P.; Remaud-Simeon, M.

    In: Biocatalysis and Biotransformation, Vol. 21, No. 4-5, 01.08.2003, p. 271-277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  134. Published

    Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4-α4 interface. / Ahring, Philip K; Olsen, Jeppe A; Nielsen, Elsebet Ø; Peters, Dan; Pedersen, Martin H F; Rohde, Line A; Kastrup, Jette Sandholm Jensen; Shahsavar, Azadeh; Indurthi, Dinesh C; Chebib, Mary; Gajhede, Michael; Balle, Thomas.

    In: Neuropharmacology, Vol. 92, 2015, p. 135-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. Published

    Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH. / Aduri, Nanda G.; Montefiori, Marco; Khalil, Ruqaiya; Gajhede, Michael; Jørgensen, Flemming Steen; Mirza, Osman.

    In: ACS Omega, Vol. 4, No. 1, 31.01.2019, p. 2040-2046.

    Research output: Contribution to journalJournal articleResearchpeer-review

  136. Published

    Human proton coupled folic acid transporter is a monodisperse oligomer in the lauryl maltose neopentyl glycol solubilized state. / Aduri, Nanda G; Ernst, Heidi A.; Prabhala, Bala K.; Bhatt, Shweta; Boesen, Thomas; Gajhede, Michael; Mirza, Osman.

    In: Biochemical and Biophysical Research Communications, Vol. 495, No. 2, 2018, p. 1738-1743.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1304192