Michael Gajhede

Michael Gajhede

Professor


  1. 2008
  2. Published
    Crystal Structure of NCAM2 Ig1 (I4122 Cell Unit). Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Kastrup, Jette Sandholm Jensen (Other); Poulsen, Jens-Christian Navarro (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  3. Published
    Crystal Structure of NCAM2 Ig1-2. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  4. Published
    Crystal Structure of NCAM2 Ig2-3. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  5. Published
    Crystal Structure of NCAM2 Ig34. Kulahin, Nikolaj (Other); Rasmussen, Kim Krighaar (Other); Kristensen, Ole (Other); Berezin, Vladimir (Other); Bock, Elisabeth Marianne (Other); Walmod, Peter Schledermann (Other); Gajhede, Michael (Other). 2008.

    Research output: Non-textual formDatasetResearch

  6. Published

    Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping. / Rasmussen, Kim Krighaar; Kulahin, Nikolaj; Kristensen, Ole; Poulsen, Jens-Christian N; Sigurskjold, Bent W; Kastrup, Jette S; Berezin, Vladimir; Bock, Elisabeth; Walmod, Peter S; Gajhede, Michael.

    In: Journal of Molecular Biology, Vol. 382, No. 5, 2008, p. 1113-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dimerization effect of sucrose octasulfate on rat FGF1. / Kulahin, Nikolaj; Kiselyov, Vladislav; Kochoyan, Artur; Kristensen, Ole; Kastrup, Jette Sandholm Jensen; Berezin, Vladimir; Bock, Elisabeth Marianne; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 64, No. Pt6, 2008, p. 448-452.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 . / Kasper, Christina; Frydenvang, Karla Andrea; Naur, Peter; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: FEBS Letters, Vol. 582, No. 29, 2008, p. 4089-4094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution. / Jørgensen, Anders Dysted; Nøhr, Jane; Kastrup, Jette Sandholm; Gajhede, Michael; Sigurskjold, Bent Walther; Sauer, Jørgen; Svergun, Dmitri I.; Svensson, Birte; Vestergaard, Bente.

    In: Journal of Biological Chemistry, Vol. 283, No. 21, 2008, p. 14772-14780.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501. / Røder, Gustav; Kristensen, Ole; Kastrup, Jette S; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 64, No. Pt 6, 2008, p. 459-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp. / Kristensen, Ole; Ross, Birthe; Gajhede, Michael.

    In: Journal of Molecular Biology, Vol. 375, No. 5, 2008, p. 1469-1476.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. / Beich-Frandsen, Mads; Pickering, Darryl S; Mirza, Osman; Johansen, Tommy N; Greenwood, Jeremy; Vestergaard, Bente; Schousboe, Arne; Gajhede, Michael; Liljefors, Tommy; Kastrup, Jette S.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 5, 2008, p. 1459-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The structure of the complex between a branched pentasaccharide and Thermobacillus xylanilyticus GH-51 arabinofuranosidase reveals xylan-binding determinants and induced fit. / Paës, Gabriel; Skov, Lars K; O'Donohue, Michael J; Rémond, Caroline; Kastrup, Jette Sandholm; Gajhede, Michael; Mirza, Osman.

    In: Biochemistry, Vol. 47, No. 28, 2008, p. 7441-7451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2007
  15. Published

    A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils. / Vestergaard, Bente; Jensen, Minna Grønning; Roessle, Manfred; Kastrup, Jette Sandholm Jensen; Van De Weert, Marco; Flink, James M.; Frøkjær, Sven; Gajhede, Michael; Svergun, Dmitri I.

    In: PLoS - Biology, Vol. 5, No. 5, 2007, p. 1089-1097.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A tetrazolyl-substituted subtype-selective AMPA receptor agonist. / Vogensen, Stine Byskov; Frydenvang, Karla Andrea; Greenwood, Jeremy R.; Postorino, Giovanna; Nielsen, Birgitte; Pickering, Darryl Scott; Ebert, Bjarke; Bølcho, Ulrik; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm Jensen; Johansen, Tommy Nørskov; Clausen, Rasmus Prætorius; Krogsgaard-Larsen, Povl.

    In: Journal of Medicinal Chemistry, Vol. 50, No. 10, 2007, p. 2408-2414.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Få kræftcellen til at begå selvmord : en strukturel vinkel på kræft. / Ross, Birthe; Borchorst, Morten; Gajhede, Michael; Kristensen, Ole.

    In: Lægemiddelforskning, 2007, p. 22-23.

    Research output: Contribution to journalJournal articleCommunication

  18. Published

    Gennembrud i forståelsen af insulinfibrillering. / Jensen, Minna Grønning; Vestergaard, Bente; Frøkjær, Sven; Gajhede, Michael; Flink, James M.; Van De Weert, Marco; Kastrup, Jette Sandholm Jensen; Svergun, Dmitri I.

    In: Lægemiddelforskning, 2007, p. 10-11.

    Research output: Contribution to journalJournal articleCommunication

  19. Published

    High resolution crystal structures of the p120 RasGAP SH3 domain. / Ross, Birthe; Kristensen, Ole; Favre, Dimitri; Walicki, Joël; Kastrup, Jette Sandholm Jensen; Widmann, Christian; Gajhede, Michael.

    In: Biochemical and Biophysical Research Communications, Vol. 353, No. 2, 2007, p. 463-468.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine. / Naur, Peter; Hansen, Kasper Bø; Kristensen, Anders Skov; Dravid, Shashank M.; Pickering, Darryl Scott; Olsen, Lars; Vestergaard, Bente; Egebjerg, Jan; Gajhede, Michael; Traynelis, Stephen F.; Kastrup, Jette Sandholm Jensen.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 104, No. 35, 2007, p. 14116-14121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Jagten på et signalstof til hjernens delta2-receptor. / Naur, Peter; Olsen, Lars; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, 2007, p. 32-33.

    Research output: Contribution to journalJournal articleCommunication

  22. Published

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5 : Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. / Hald, Helle; Naur, Peter; Pickering, Darryl Scott; Sprogøe, Desiree; Madsen, Ulf; Timmermann, Daniel B.; Ahring, Philip K.; Liljefors, Tommy; Schousboe, Arne; Egebjerg, Jan; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Journal of Biological Chemistry, Vol. 282, No. 35, 2007, p. 25726-25736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites. / Kaae, Birgitte Høiriis; Harpsøe, Kasper; Kastrup, Jette Sandholm Jensen; Sanz, Alberto Contreras; Pickering, Darryl Scott; Metzler, Bjørn; Clausen, Rasmus Prætorius; Gajhede, Michael; Sauerberg, Per; Liljefors, Tommy; Madsen, Ulf.

    In: Chemistry & Biology, Vol. 14, No. 11, 2007, p. 1294-303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Structure of rat acidic fibroblast growth factor at 1.4 A resolution. / Kulahin, Nikolaj; Kiselyov, Vladislav; Kochoyan, Artur; Kristensen, Ole; Kastrup, Jette Sandholm Jensen; Berezin, Vladimir; Bock, Elisabeth Marianne; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 63, No. Pt2, 2007, p. 65-68.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Towards the molecular understanding of glycogen elongation by amylosucrase. / Albenne, Cécile; Skov, Lars K.; Tran, Vinh; Gajhede, Michael; Monsan, Pierre; Remaud-Siméon, Magali; André-Leroux, Gwénaëlle.

    In: Proteins - Structure Function and Bioinformatics, Vol. 66, No. 1, 2007, p. 118-126.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2006
  27. Published

    Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose. / Skov, Lars K.; Mirza, Osman; Sprogøe, Desiree; van der Veen, Bart; Remaud-Simeon, Magali; Albenne, Cecile; Monsan, Pierre; Gajhede, Michael.

    In: Biocatalysis and Biotransformation, Vol. 24, No. 1-2, 01.01.2006, p. 99-105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A unique set of SH3-SH3 interactions controls IB1 homodimerization. / Kristensen, Ole; Guenat, Sylvie; Dar, Imran; Allaman-Pillet, Nathalie; Abderrahmani, Amar; Ferdaoussi, Mourad; Roduit, Raphaël; Maurer, Fabienne; Beckmann, Jacques S; Kastrup, Jette S; Gajhede, Michael; Bonny, Christophe.

    In: E M B O Journal, Vol. 25, No. 4, 2006, p. 785-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype. / Røder, Gustav; Blicher, Thomas; Justesen, Sune; Johannesen, Birthe; Kristensen, Ole; Kastrup, Jette; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 62, No. Pt 11, 2006, p. 1300-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Hvad har varme at gøre med lægemidler? / Olsen, Lars; Kasper, Christina; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Jørgensen, Flemming Steen.

    In: Lægemiddelforskning, 2006, p. 31-33.

    Research output: Contribution to journalJournal articleCommunication

  31. Published

    Increased amylosucrase activity and specificity, and identification of regions important for activity, specificity and stability through molecular evolution. / van der Veen, Bart A; Skov, Lars K; Potocki-Véronèse, Gabrielle; Gajhede, Michael; Monsan, Pierre; Remaud-Simeon, Magali.

    In: F E B S Journal, Vol. 273, No. 4, 2006, p. 673-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion. / Mirza, Osman; Henriksen, Lars Skov; Sprogøe, Desiree; van den Broek, Lambertus A M; Beldman, Gerrit; Kastrup, Jette S; Gajhede, Michael.

    In: Journal of Biological Chemistry, Vol. 281, No. 46, 2006, p. 35576-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue. / Blicher, Thomas; Kastrup, Jette Sandholm; Pedersen, Lars Østergaard; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica Section F-Structural Biology and Crystallization Communications, Vol. 62, No. Pt 12, 2006, p. 1179-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Structure of recombinant Ves v 2 at 2.0 Angstrom resolution : structural analysis of an allergenic hyaluronidase from wasp venom. / Skov, Lars K; Seppälä, Ulla; Coen, Jeremy J F; Crickmore, Neil; King, Te P; Monsalve, Rafael; Kastrup, Jette S; Spangfort, Michael D; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 62, No. Pt 6, 2006, p. 595-604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The metal binding site of the major house dust mite allergen Der p 1. / Meno, Kåre; Thorsted, Peter B; Ipsen, Henrik; Kristensen, Ole; Larsen, Jørgen; Spangfort, Michael D; Gajhede, Michael; Lund, Kaare.

    In: Journal of Allergy and Clinical Immunology, Vol. 118, No. 4, 2006, p. 971.

    Research output: Contribution to journalComment/debateResearchpeer-review

  36. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209. / Kasper, Christina; Pickering, Darryl S; Mirza, Osman; Olsen, Lars; Kristensen, Anders S; Greenwood, Jeremy R; Liljefors, Tommy; Schousboe, Arne; Wätjen, Frank; Gajhede, Michael; Sigurskjold, Bent W; Kastrup, Jette S.

    In: Journal of Molecular Biology, Vol. 357, No. 4, 2006, p. 1184-201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2005
  38. Published

    Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network. / Petersson, Britt; Nielsen, Bettina Bryde; Rasmussen, Hanne; Larsen, Ingrid Kjøller; Gajhede, Michael; Nielsen, Peter E; Kastrup, Jette Sandholm Jensen.

    In: Journal of the American Chemical Society, Vol. 127, No. 5, 09.02.2005, p. 1424-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Conformational stability of calreticulin. / Jørgensen, Charlotte S; Trandum, Christa; Larsen, Nanna Brink; Ryder, L Rebekka; Gajhede, Michael; Skov, Lars; Højrup, Peter; Barkholt, Vibeke; Houen, Gunnar.

    In: Protein and Peptide Letters, Vol. 12, No. 7, 2005, p. 687-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate. / Naur, Peter; Vestergaard, Bente; Skov, Lars; Egebjerg, Jan ; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: FEBS letters, Vol. 579, 2005, p. 1154-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP. / Nielsen, Bettina B; Pickering, Darryl S; Greenwood, Jeremy R; Brehm, Lotte; Gajhede, Michael; Schousboe, Arne; Kastrup, Jette S.

    In: FEBS Journal, Vol. 272, No. 7, 2005, p. 1639-48.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Expression, crystallization and preliminary X-ray analysis of the extracellular Ig modules I-IV and F3 modules I-III of the neural cell-adhesion molecule L1. / Kulahin, Nikolaj; Kasper, Christina; Kristensen, Ole; Kastrup, Jette Sandholm; Berezin, Vladimir; Bock, Elisabeth; Gajhede, Michael.

    In: Acta Crystallographica. Section F : Structural Biology and Crystallization Communications, Vol. 61, No. Pt 9, 2005, p. 858-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide. / Blicher, Thomas; Kastrup, Jette Sandholm; Buus, Søren; Gajhede, Michael.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 61, No. Pt 8, 2005, p. 1031-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Structure of the house dust mite allergen Der f 2 : implications for function and molecular basis of IgE cross-reactivity. / Johannessen, Birthe R; Skov, Lars; Kastrup, Jette S; Kristensen, Ole; Bolwig, Caroline; Larsen, Jørgen; Spangfort, Michael; Lund, Kaare; Gajhede, Michael.

    In: F E B S Letters, Vol. 579, No. 5, 2005, p. 1208-12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure. / Vestergaard, Bente; Sanyal, Suparna; Roessle, Manfred; Mora, Liliana; Buckingham, Richard; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Svergun, Dmitri I; Ehrenberg, Måns.

    In: Molecular Cell, Vol. 20, 2005, p. 929-938.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The crystal structure of recombinant proDer p 1, a major house dust mite proteolytic allergen. / Meno, Kåre; Thorsted, Peter B; Ipsen, Henrik; Kristensen, Ole; Larsen, Jørgen; Spangfort, Michael D; Gajhede, Michael; Lund, Kaare.

    In: Journal of Immunology, Vol. 175, No. 6, 2005, p. 3835-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2. / Frandsen, Anne; Pickering, Darryl S.; Vestergaard, Bente; Kasper, Christina; Nielsen, Bettina Bryde; Greenwood, Jeremy R; Campiani, Giuseppe; Fattorusso, Caterina; Gajhede, Michael; Schousboe, Arne; Kastrup, Jette Sandholm.

    In: Molecular Pharmacology, Vol. 67, No. 3, 2005, p. 703-13.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2004
  49. Published

    Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea. / Jensen, Malene H; Mirza, Osman Asghar; Albenne, Cecile; Remaud-Simeon, Magali; Monsan, Pierre; Gajhede, Michael; Skov, Lars.

    In: Biochemistry, Vol. 43, No. 11, 23.03.2004, p. 3104-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Expression, crystallization and preliminary X-ray analysis of extracellular modules of the neural cell-adhesion molecules NCAM and L1. / Kulahin, Nikolaj; Kasper, Christina; Gajhede, Michael; Berezin, Vladimir; Bock, Elisabeth; Kastrup, Jette Sandholm Jensen.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 60, No. Pt 3, 03.2004, p. 591-3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis. / Sprogøe, Desiree; van den Broek, Lambertus A M; Mirza, Osman; Kastrup, Jette Sandholm Jensen; Voragen, Alphons G J; Gajhede, Michael; Skov, Lars.

    In: Biochemistry, Vol. 43, No. 5, 10.02.2004, p. 1156-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase. / Albenne, Cécile; Skov, Lars; Mirza, Osman Asghar; Gajhede, Michael; Feller, Georges; D'Amico, Salvino; André, Gwénaëlle; Potocki-Véronèse, Gabrielle; van der Veen, Bart A; Monsan, Pierre; Remaud-Simeon, Magali.

    In: Journal of Biological Chemistry, Vol. 279, No. 1, 02.01.2004, p. 726-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family. / Kristensen, Ole; Laurberg, Martin; Liljas, Anders; Kastrup, Jette Sandholm Jensen; Gajhede, Michael.

    In: Biochemistry, Vol. 43, No. 28, 2004, p. 8894-900.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1304192