Michael Gajhede

Michael Gajhede

Professor


  1. Published

    Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. / Kvist, Trine; Steffensen, Thomas Bielefeldt; Greenwood, Jeremy R; Mehrzad Tabrizi, Fatemeh; Hansen, Kasper Bø; Gajhede, Michael; Pickering, Darryl S; Traynelis, Stephen F; Kastrup, Jette Sandholm; Bräuner-Osborne, Hans.

    In: The Journal of Biological Chemistry, Vol. 288, 2013, p. 33124-35.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors. / Lohse, Brian; Nielsen, Anders L; Kristensen, Jan B L; Helgstrand, Charlotte; Cloos, Paul Andreas Compare; Olsen, Lars; Gajhede, Michael; Clausen, Rasmus Prætorius; Kristensen, Jesper Langgaard.

    In: Angewandte Chemie International Edition, Vol. 50, No. 39, 19.09.2011, p. 9100-9103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Inhibitors of histone demethylases. / Lohse, Brian; Kristensen, Jesper L; Kristensen, Line H; Agger, Karl; Helin, Kristian; Gajhede, Michael; Clausen, Rasmus P.

    In: Bioorganic & Medicinal Chemistry, Vol. 19, No. 12, 01.02.2011, p. 3625-3636.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1. / Meno, Kåre H; Kastrup, Jette S; Kuo, I-Chun; Chua, Kaw Yan; Gajhede, Michael.

    In: Allergy, Vol. 72, No. 4, 13111, 01.04.2017, p. 665-670.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Jagten på et signalstof til hjernens delta2-receptor. / Naur, Peter; Olsen, Lars; Gajhede, Michael; Kastrup, Jette Sandholm Jensen.

    In: Lægemiddelforskning, 2007, p. 32-33.

    Research output: Contribution to journalJournal articleCommunication

  6. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine. / Naur, Peter; Hansen, Kasper Bø; Kristensen, Anders Skov; Dravid, Shashank M.; Pickering, Darryl Scott; Olsen, Lars; Vestergaard, Bente; Egebjerg, Jan; Gajhede, Michael; Traynelis, Stephen F.; Kastrup, Jette Sandholm Jensen.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 104, No. 35, 2007, p. 14116-14121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Identification of catechols as histone-lysine demethylase inhibitors. / Nielsen, Anders L; Kristensen, Line H; Stephansen, Karen B; Kristensen, Jan B L; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Helin, Kristian; Gajhede, Michael; Olsen, Lars.

    In: F E B S Letters, Vol. 586, No. 8, 2012, p. 1190-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structural and functional studies of the modulator NS9283 reveal agonist-like mechanism of action at α4β2 nicotinic acetylcholine receptors. / Olsen, Jeppe A; Ahring, Philip K; Kastrup, Jette Sandholm Jensen; Gajhede, Michael; Balle, Thomas.

    In: The Journal of Biological Chemistry, Vol. 289, No. 36, 05.09.2014, p. 24911-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Two distinct allosteric binding sites at α4β2 nicotinic acetylcholine receptors revealed by NS206 and NS9283 give unique insights to binding activity-associated linkage at Cys-loop receptors. / Olsen, Jeppe A.; Kastrup, Jette Sandholm Jensen; Peters, Dan; Gajhede, Michael; Balle, Thomas; Ahring, Philip K.

    In: Journal of Biological Chemistry, Vol. 288, No. 50, 13.12.2013, p. 35997.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors. / Olsen, Jeppe A.; Balle, Thomas; Gajhede, Michael; Ahring, Philip K.; Kastrup, Jette Sandholm Jensen.

    In: PLOS ONE, Vol. 9, No. 3, 17.03.2014, p. e91232.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1304192