Michael Gajhede

Michael Gajhede

Professor


  1. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    At være eller ikke være en antagonist

    Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2009, In : Lægemiddelforskning. p. 43-45

    Research output: Contribution to journalJournal articleCommunication

  3. Published
  4. Published

    Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHßE Suggests a Unique Mode of Antagonism

    Shahsavar, A., Kastrup, Jette Sandholm Jensen, Nielsen, E. Ø., Kristensen, Jesper Langgaard, Gajhede, Michael & Balle, T., 2012, In : P L o S One. 7, 8, p. e40757

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Crystal Structure of NCAM2 Ig1 (I4122 Cell Unit)

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Poulsen, Jens-Christian Navarro, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008

    Research output: Non-textual formDatasetResearch

  6. Published

    Crystal Structure of NCAM2 Ig1-2

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008

    Research output: Non-textual formDatasetResearch

  7. Published

    Crystal Structure of NCAM2 Ig2-3

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008

    Research output: Non-textual formDatasetResearch

  8. Published

    Crystal Structure of NCAM2 Ig34

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2008

    Research output: Non-textual formDatasetResearch

  9. Published

    Crystal structure of NCAM2 IgIV-Fn3I

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2009

    Research output: Non-textual formDatasetResearch

  10. Published

    Crystal structure of NCAM2 IgIV-Fn3II

    Kulahin, N., Rasmussen, K. K., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M., Walmod, P. S. & Gajhede, Michael, 2009

    Research output: Non-textual formDatasetResearch

  11. Published

    Crystal structure of the Ig1 domain of the neural cell adhesion molecule NCAM2 displays domain swapping.

    Rasmussen, K. K., Kulahin, N., Kristensen, O., Poulsen, Jens-Christian Navarro, Sigurskjold, B. W., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E., Walmod, P. S. & Gajhede, Michael, 2008, In : Journal of Molecular Biology. 382, 5, p. 1113-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dimerization effect of sucrose octasulfate on rat FGF1.

    Kulahin, N., Kiselyov, V., Kochoyan, A., Kristensen, O., Kastrup, Jette Sandholm Jensen, Berezin, V., Bock, E. M. & Gajhede, Michael, 2008, In : Acta Crystallographica. Section F : Structural Biology and Crystallization Communications. 64, Pt6, p. 448-452 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2

    Hald, H., Ahring, P. K., Timmermann, D. B., Liljefors, T., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2009, In : Journal of Molecular Biology. 391, 5, p. 906-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1

    Holm, J., Ferreras, M., Ipsen, H., Würtzen, P. A., Gajhede, Michael, Larsen, J. N., Lund, K. & Spangfort, M. D., 20 May 2011, In : Journal of Biological Chemistry. 286, 20, p. 17569-17578

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine

    Frydenvang, Karla Andrea, Lash, L. L., Naur, P., Postila, P. A., Pickering, Darryl S, Smith, C. M., Gajhede, Michael, Sasaki, M., Sakai, R., Pentikäinen, O. T., Swanson, G. T. & Kastrup, Jette Sandholm Jensen, 2009, In : Journal of Biological Chemistry. 284, 21, p. 14219-14229

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification of catechols as histone-lysine demethylase inhibitors

    Nielsen, A. L., Kristensen, L. H., Stephansen, K. B., Kristensen, J. B. L., Helgstrand, C., Lees, M., Cloos, Paul, Helin, Kristian, Gajhede, Michael & Olsen, L., 2012, In : F E B S Letters. 586, 8, p. 1190-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Inhibitors of histone demethylases

    Lohse, Brian, Kristensen, Jesper Langgaard, Kristensen, L. H., Agger, Karl, Helin, Kristian, Gajhede, Michael & Clausen, Rasmus Prætorius, 1 Feb 2011, In : Bioorganic & Medicinal Chemistry. 19, 12, p. 3625-3636 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: Unique role of halogen bonding revealed

    Rohde, L. A. H., Ahring, P. K., Jensen, M. L., Nielsen, E. Ø., Peters, D., Helgstrand, C., Krintel, C., Harpsøe, Kasper, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Balle, T., 3 Feb 2012, In : The Journal of Biological Chemistry. 287, 6, p. 4248-4259

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Kainate induces various domain closures in AMPA and kainate receptors

    Venskutonyte, R., Frydenvang, Karla Andrea, Hald, H., Rabassa, A. C. D., Gajhede, Michael, Ahring, P. K. & Kastrup, Jette Sandholm Jensen, Sep 2012, In : Neurochemistry International. 61, 4, p. 536-545

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Modulation of the dimer interface at ionotropic glutamate-like receptor d2 by D-serine and extracellular calcium

    Hansen, K. B., Naur, P., Kurtkaya, N. L., Kristensen, Anders Skov, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., 2009, In : Journal of Neuroscience. 29, 4, p. 907-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

    Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In : FEBS Letters. 582, 29, p. 4089-4094

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor

    Owczarek, S., Kiryushko, D., Hald Larsen, M., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Sandi, C., Berezin, V., Bock, E. & Soroka, V., 2010, In : The FASEB Journal. 24, 4, p. 1139-1150 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus

    Wang, X., Hald, H., Ernst, H. A., Egebjerg, J., Christensen, K. V., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Mirza, Osman Asghar, 2010, In : Protein Expression and Purification. 71, 2, p. 179-183

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors

    Juknaite, L., Venskutonyte, R., Assaf, Z., Faure, S., Gefflaut, T., Aitken, D. J., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Bunch, Lennart, Frydenvang, Karla Andrea & Pickering, Darryl S, 2012, In : Journal of Structural Biology. 180, 1, p. 39-46

    Research output: Contribution to journalJournal articleResearchpeer-review

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