Miriam Kolko

Miriam Kolko

Professor with special responsibilities, Clinical Associate Professor


  1. 1996
  2. Published

    Synergy by secretory phospholipase A2 and glutamate on inducing cell death and sustained arachidonic acid metabolic changes in primary cortical neuronal cultures. / Kolko, M; DeCoster, M A; de Turco, E B; Bazan, N G; Kolko, Miriam.

    In: The Journal of Biological Chemistry, Vol. 271, No. 51, 20.12.1996, p. 32722-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1999
  4. Published

    Secretory phospholipase A2 potentiates glutamate-induced rat striatal neuronal cell death in vivo. / Kolko, M; Bruhn, T; Christensen, Thomas; Lazdunski, M; Lambeau, G; Bazan, N G; Diemer, Nils Henrik.

    In: Neuroscience Letters, Vol. 274, No. 3, 1999, p. 167-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2002
  6. Published

    Glutamate signalling and secretory phospholipase A2 modulate the release of arachidonic acid from neuronal membranes. / Rodriguez De Turco, Elena B; Jackson, Fannie R; DeCoster, Mark A; Kolko, Miriam; Bazan, Nicolas G; Kolko, Miriam.

    In: Journal of Neuroscience Research, Vol. 68, No. 5, 01.06.2002, p. 558-67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Secretory phospholipase A(2) induces delayed neuronal COX-2 expression compared with glutamate. / Kolko, Miriam; Nielsen, Marianne; Bazan, Nicolas G; Diemer, Nils H; Kolko, Miriam.

    In: Journal of Neuroscience Research, Vol. 69, No. 2, 15.07.2002, p. 169-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Secretory phospholipase A2-mediated neuronal cell death involves glutamate ionotropic receptors. / Kolko, Miriam; de Turco, Elena B; Diemer, Nils Henrik; Bazan, Nicolas G; Kolko, Miriam.

    In: NeuroReport, Vol. 13, No. 15, 28.10.2002, p. 1963-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2003
  10. Published

    Neuronal damage by secretory phospholipase A2 : modulation by cytosolic phospholipase A2, platelet-activating factor, and cyclooxygenase-2 in neuronal cells in culture. / Kolko, Miriam; Rodriguez de Turco, Elena B; Diemer, Nils H; Bazan, Nicolas G; Kolko, Miriam.

    In: Neuroscience Letters, Vol. 338, No. 2, 27.02.2003, p. 164-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2004
  12. Published

    Expression and location of mRNAs encoding multiple forms of secretory phospholipase A2 in the rat retina. / Kolko, Miriam; Christoffersen, Nanna R; Barreiro, Sebastian G; Bazan, Nicolas G; Kolko, Miriam.

    In: Journal of Neuroscience Research, Vol. 77, No. 4, 15.08.2004, p. 517-24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2005
  14. Published

    Expression and induction of secretory phospholipase A2 group IB in brain. / Kolko, Miriam; Christoffersen, Nanna R; Varoqui, Hélène; Bazan, Nicolas G.

    In: Cellular & Molecular Neurobiology, Vol. 25, No. 7, 11.2005, p. 1107-22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2006
  16. Characterization and location of secretory phospholipase A2 groups IIE, V, and X in the rat brain. / Kolko, Miriam; Christoffersen, Nanna Rønbjerg; Barreiro, S.G.; Miller, M.L.; Pizza, A.J.; Bazan, N.G.

    In: Journal of Neuroscience Research, Vol. 83, No. 5, 2006, p. 874-882.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2007
  18. Published

    Mulig terapeutisk intervention med haemmere og fremmere af fosfolipase A 2 -subtyper. / Kolko, Miriam; Zhan, Chen; Andreasen, Jens Rovelt; Prause, Jan Ulrik; Heegaard, Steffen; Kolko, Miriam.

    In: Ugeskrift for Laeger, Vol. 169, No. 2, 08.01.2007, p. 115-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Human secretory phospholipase A(2), group IB in normal eyes and in eye diseases. / Kolko, Miriam; Prause, Jan U; Bazan, Nicolas G; Heegaard, Steffen; Kolko, Miriam.

    In: Acta Ophthalmologica, Vol. 85, No. 3, 05.2007, p. 317-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2008
  21. Published

    Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy. / Alyahya, Ghassan Ayish; Kolko, Miriam; Prause, Jan Ulrik; Nielsen, Boye Schnack; Wang, Jinmei; Heegaard, Steffen; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 49, No. 7, 07.2008, p. 2806-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2009
  23. Published

    Cyclooxygenase-2 immunoreactivity in collagenous colitis. / Wildt, Signe; Rumessen, Jüri J; Csillag, Claudio; Normark, Michel; Poulsen, Kristian Arild; Kolko, Miriam; Wildt, Signe; Rumessen, Jüri J; Csillag, Claudio; Normark, Michel; Poulsen, Kristian Arild; Kolko, Miriam.

    In: Acta Pathologica Microbiologica et Immunologica Scandinavica, Vol. 117, No. 7, 01.07.2009, p. 500-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Calcium-independent phospholipase A2 regulates retinal pigment epithelium proliferation and may be important in the pathogenesis of retinal diseases. / Kolko, M; Kiilgaard, J F; Wang, J; Poulsen, K A; Andreasen, J R; la Cour, M; Nissen, M H; Heegaard, S; Bazan, N G; Prause, J U; Kolko, M; Kiilgaard, J F; Wang, J; Poulsen, K A; Andreasen, J R; la Cour, M; Nissen, M H; Heegaard, S; Bazan, N G; Prause, J U.

    In: Experimental Eye Research, Vol. 89, No. 3, 01.09.2009, p. 383-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2010
  26. Published

    Phospholipases A2 in ocular homeostasis and diseases. / Wang, Jinmei; Kolko, Miriam; Kolko, Miriam.

    In: Biochimie, Vol. 92, No. 6, 06.2010, p. 611-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2011
  28. Published

    Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours. / Wang, Jinmei; Wu, Yazhen; Heegaard, Steffen; Kolko, Miriam.

    In: Acta Ophthamologica (Online), 11.2011, p. 681-685.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2012
  30. Published

    Interaction between VEGF and Calcium-Independent Phospholipase A(2) in Proliferation and Migration of Retinal Pigment Epithelium. / Toft-Kehler, Anne Katrine; Andersen, Emelie Cammilla; Andreasen, Jens Rovelt; Vohra, Rupali; Nielsen, Nanna Maria Junker; Poulsen, Kristian Arild; Kolko, Miriam; Toft-Kehler, Anne Katrine.

    In: Current Eye Research, Vol. 37, No. 6, 01.06.2012, p. 500-507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Diverse regulation of retinal pigment epithelium phagocytosis of photoreceptor outer segments by calcium-independent phospholipase A₂, group VIA and secretory phospholipase A₂, group IB. / Zhan, Chen; Wang, Jinmei; Kolko, Miriam.

    In: Current Eye Research, Vol. 37, No. 10, 10.2012, p. 930-940.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Grøn stær er andet end forhøjet tryk i øjet. / Kolko, Miriam; Skytt, Dorte M.

    In: Oftalmolog, 12.2012, p. 18-21.

    Research output: Contribution to journalJournal articleResearch

  33. 2013
  34. Published

    The role of inflammation in the pathogenesis of glaucoma. / Vohra, Rupali; Tsai, James C; Kolko, Miriam.

    In: Survey of Ophthalmology, Vol. 58, No. 4, 19.06.2013, p. 311-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2014
  36. Published

    MicroRNA expression analysis and Multiplex ligation-dependent probe amplification in metastatic and non-metastatic uveal melanoma. / Larsen, Ann-Cathrine; Holst, Line Marie; Kaczkowski, Bogumil; Andersen, Morten Tolstrup; Manfé, Valentina; Siersma, Volkert Dirk; Kolko, Miriam; Kiilgaard, Jens Folke; Winther, Ole; Prause, Jan Ulrik; Gniadecki, Robert; Heegaard, Steffen.

    In: Acta Ophthalmologica, Vol. 92, No. 6, 2014, p. 541-549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2015
  38. Published

    Lactate transport and receptor actions : Potential roles in inner retinal function and disease. / Vohra, R.; Vosborg, F.; Henriksen, U.; Gurubaran, I.S.; Hasan-Olive, M.; Holm, E.; Skytt, D.; Gjedde, A.; Storm-Mathisen, J.; Kolko, M.; Bergersen, L.H.

    In: Acta Ophthalmologica, Vol. 93, No. S255, ABS15‐0601, 2015.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    Present and New Treatment Strategies in the Management of Glaucoma. / Kolko, Miriam.

    In: The Open Ophthalmology Journal, Vol. 9, No. Suppl 1: M5, 2015, p. 89-100.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Evaluation of Damato Multifixation Campimetry Online, an online visual field test, in detection of glaucomatous defects. / Olsen, Ane Sophie; Alberti, Mark; Dornonville de la Cour, Morten; Serup, Lisbeth; Damato, Bertil E.; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 56, No. 7, 06.2015, p. 1050.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  41. Published

    Oxidative Stress in Retinal Muller Cells contributes to Dysfunction of Retinal Glutamate Uptake and Altered Protein Expression. / Toft-Kehler, Anne Katrine; Skytt, Dorte Marie; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 56, No. 7, 3672, 06.2015.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    The Prevalence and Incidence of Glaucoma in Denmark in a Fifteen Year Period : A Nationwide Study. / Kolko, Miriam; Horwitz, Anna; Thygesen, John; Jeppesen, Jorgen; Torp-Pedersen, Christian.

    In: P L o S One, Vol. 10, No. 7, e0132048, 16.07.2015, p. 1-11.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2016
  44. Published

    Danish Nationwide Data Reveal a Link between Diabetes Mellitus, Diabetic Retinopathy, and Glaucoma. / Horwitz, Anna; Petrovski, Beata Eva; Torp-Pedersen, Christian; Kolko, Miriam.

    In: Journal of Diabetes Research, Vol. 2016, 2684674, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells. / Skytt, D. M.; Toft-Kehler, A. K.; Braendstrup, C. T.; Cejvanovic, S; Gurubaran, I. S.; Bergersen, L. H.; Kolko, M.

    In: Journal of Biomedicine and Biotechnology, Vol. 2016, 1087647, 2016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Glaucoma detection with damato multifixation campimetry online. / Olsen, Ane Sophie; Alberti, M.; Serup, L.; Dornonville de la Cour, Morten; Damato, B.; Kolko, M.

    In: Eye, Vol. 30, No. 5, 05.2016, p. 731-739.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation. / Toft-Kehler, Anne Katrine; Gurubaran, Iswariyaraja Sridevi; Madsen, Claus Desler; Rasmussen, Lene J.; Skytt, Dorte Marie; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 6, 05.2016, p. 2721-2728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Lactate Transport and Receptor Actions in Retina : Potential Roles in Retinal Function and Disease. / Kolko, Miriam; Vosborg, Fia; Henriksen, Jens Ulrik Lütken; Hasan-Olive, Md Mahdi; Diget, Elisabeth Holm; Vohra, Rupali; Gurubaran, Iswariyaraja Sridevi; Gjedde, Albert; Mariga, Shelton Tendai; Skytt, Dorte M; Utheim, Tor Paaske; Storm-Mathisen, Jon; Bergersen, Linda H.

    In: Neurochemical Research, Vol. 41, No. 6, 01.06.2016, p. 1229-1236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2017
  50. Published

    Can DMCO Detect Visual Field Loss in Neurological Patients? A Secondary Validation Study. / Olsen, Ane Sophie; Steensberg, Alvilda Thougaard; la Cour, Morten; Kjaer, Troels Wesenberg; Damato, Bertil; Pinborg, Lars Hageman; Kolko, Miriam.

    In: Ophthalmic Research, Vol. 58, No. 2, 2017, p. 85-93.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1. / Vohra, Rupali; Gurubaran, Iswariyaraja Sridevi; Henriksen, Ulrik ; Bergersen, Linda Hildegaard; Rasmussen, Lene Juel; Desler, Claus; Skytt, Dorte Marie; Kolko, Miriam.

    In: Mitochondrion, Vol. 36, 2017, p. 52-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Mitochondrial dysfunction underlying outer retinal diseases. / Lefevere, Evy; Toft-Kehler, Anne Katrine; Vohra, Rupali; Kolko, Miriam; Moons, Lieve; Van Hove, Inge.

    In: Mitochondrion, Vol. 36, 2017, p. 66-76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Mitochondrial function in Müller cells - Does it matter? / Toft-Kehler, Anne Katrine; Skytt, Dorte Marie; Svare, Alicia; Lefevere, Evy; Van Hove, Inge; Moons, Lieve; Waagepetersen, Helle S.; Kolko, Miriam.

    In: Mitochondrion, Vol. 36, 2017, p. 43-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Detection and prevention of blindness in patients with glaucoma is a socio-economical challenge. / Kolko, Miriam.

    In: Ugeskrift for Laeger, Vol. 179, No. 5, 30.01.2017.

    Research output: Contribution to journalReviewResearchpeer-review

  55. Published

    Antihypertensive Medication Postpones the Onset of Glaucoma Evidence From a Nationwide Study. / Horwitz, Anna; Klemp, Marc; Jeppesen, Jorgen; Tsai, James C.; Torp-Pedersen, Christian; Kolko, Miriam.

    In: Hypertension, Vol. 69, No. 2, 02.2017, p. 202-210.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    The physical properties of generic latanoprost ophthalmic solutions are not identical. / Kolko, Miriam; Koch Jensen, Peter.

    In: Acta Ophthalmologica, Vol. 95, No. 4, 06.2017, p. 370-373.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Mitochondria and the eye diseases - Editorial. / Kolko, M.

    In: Mitochondrion, Vol. 36, 09.2017, p. 1-3.

    Research output: Contribution to journalEditorialResearchpeer-review

  58. 2018
  59. Published

    Essential Roles of Lactate in Müller Cell Survival and Function. / Vohra, Rupali; Aldana Garcia, Blanca Irene; Skytt, Dorte M; Freude, Kristine; Waagepetersen, Helle S.; Bergersen, Linda Hildegard; Kolko, Miriam.

    In: Molecular Neurobiology, Vol. 55, No. 12, 2018, p. 9108-9121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Generation of transgene-free porcine intermediate type induced pluripotent stem cells. / Li, Dong; Secher, Jan; Hyttel, Poul; Ivask, Marilin; Kolko, Miriam; Hall, Vanessa Jane; Freude, Kristine K.

    In: Cell Cycle, Vol. 17, No. 23, 2018, p. 2547-2563.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Potential link between sporadic cerebral amyloid angiopathy and vision loss : a case report. / Vohra, Rupali; Hjortshøj, Tina D.; Nordling, Mette M.; Sørensen, Torben L.; Jensen, Peter K.; Kolko, Miriam.

    In: Acta Ophthalmologica, Vol. 96, No. 6, 2018, p. e753-e755.

    Research output: Contribution to journalComment/debateResearch

  62. Published

    Potential metabolic markers in glaucoma and their regulation in response to hypoxia. / Tiedemann, D.; Vohra, R.; Dalgaard, L. Marie; Jensen, J. Viblk; Bergersen, L. Hildegaard; Olsen, N. Vidiendal; Hassel, B.; Chaudhry, F. Abbas; Kolko, M.

    In: Acta Ophthalmologica, Vol. 96, No. 261/S1, F012 , 2018, p. 125-126.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  63. Published

    Visual field defects after temporal lobe resection for epilepsy. / Steensberg, Alvilda T; Olsen, Ane Sophie; Litman, Minna; Jespersen, Bo; Kolko, Miriam; Pinborg, Lars H.

    In: Seizure, Vol. 54, 01.2018, p. 1-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    A Perspective on the Müller Cell-Neuron Metabolic Partnership in the Inner Retina. / Toft-Kehler, A K; Skytt, D M; Kolko, Miriam.

    In: Molecular Neurobiology, Vol. 55, No. 6, 06.2018, p. 5353–5361.

    Research output: Contribution to journalReviewResearchpeer-review

  65. Published

    Muller cell survival and function is maintained by the presence of lactate. / Vohra, Rupali; Skytt, Dorte Marie; Aldana, Blanca I.; Freude, Kristine; Waagepetersen, Helle; Bergersen, Linda Hildegaard; Kolko, Miriam.

    2018. 1480 Abstract from Arvo 2018 , Honolulu, Hawaii, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  66. Published

    Oxidative stress and mitochondrial function in Muller cells. / Kolko, Miriam.

    2018. 5998 Abstract from Arvo 2018 , Honolulu, Hawaii, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  67. Published

    Cannabis og glaukom. / Mouhammad, Zaynab Ahmad; Kolko, Miriam.

    In: Ugeskrift for Laeger, Vol. 180, V11170861, 16.07.2018, p. 2-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Neuroprotection of the inner retina: Muller cells and lactate. / Vohra, Rupali; Kolko, Miriam.

    In: Neural Regeneration Research, Vol. 13, No. 10, 10.2018, p. 1741-1742.

    Research output: Contribution to journalEditorialResearchpeer-review

  69. Published

    Incidence and prevalence of glaucoma in native and immigrant groups living in Denmark. / Horwitz, Anna; Klemp, Marc Patrick Brag; Torp-Pedersen, C; Kolko, Miriam.

    In: Acta Ophthalmologica, Vol. 96, No. S261, 01.12.2018, p. 53.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  70. 2019
  71. E-pub ahead of print

    Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment. / Tiedemann, Daniel; Mouhammad, Zaynab A; Utheim, Tor P; Dartt, Darlene A; Heegaard, Steffen; Petrovski, Goran; Kolko, Miriam.

    In: Journal of Glaucoma, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. E-pub ahead of print

    Detection of visual field defects by opticians - with Damato Multifixation Campimetry Online. / Olsen, Ane Sophie; la Cour, Morten; Damato, Bertil; Kolko, Miriam.

    In: Acta Ophthalmologica, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. E-pub ahead of print

    Potential metabolic markers in glaucoma and their regulation in response to hypoxia. / Vohra, Rupali; Dalgaard, Line Marie; Vibaek, Jeppe; Langbøl, Mia Aggergaard; Bergersen, Linda Hildegaard; Olsen, Niels Vidiendal; Hassel, Bjørnar; Chaudhry, Farrukh Abbas; Kolko, Miriam.

    In: Acta Ophthalmologica, 28.01.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Dual Properties of Lactate in Müller Cells : The Effect of GPR81 Activation. / Vohra, Rupali; Aldana, Blanca I.; Waagepetersen, Helle; Bergersen, Linda H.; Kolko, Miriam.

    In: Investigative Ophthalmology & Visual Science, Vol. 60, No. 4, 01.03.2019, p. 999-1008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment. / Tiedemann, Daniel; Mouhammad, Zaynab A.; Utheim, Tor P.; Dartt, Darlene A.; Heegaard, Steffen; Petrovski, Goran; Kolko, Miriam.

    In: Journal of Glaucoma, Vol. 28, No. 4, 01.04.2019, p. 325-333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Lactate-Mediated Protection of Retinal Ganglion Cells. / Vohra, Rupali; Aldana, Blanca I.; Bulli, Giorgia; Skytt, Dorte M.; Waagepetersen, Helle; Bergersen, Linda H.; Kolko, Miriam.

    In: Journal of Molecular Biology, Vol. 431, No. 9, 19.04.2019, p. 1878-1888.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 14599192