Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor emeritus


  1. 2019
  2. Published

    Community pharmacies as platform for collection of real-world evidence of medicines usage explored through a pilot study: From standard T2D medication to treatment with the injectable combination product Xultophy. / Alkis, N; Nørgaard, Lotte Stig; Bjerrum, Ole Jannik.

    2019. Poster session presented at Årsmøde i Dansk Farmakologisk Selskab, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  3. Published

    Body of evidence and approaches applied in the clinical development program of fixed-dose combinations in the European Union from 2010-2016. / Nøhr-Nielsen, Asbjørn; De Bruin, Marie Louise; Thomsen, Mikael; Pipper, Christian Bressen; Lange, Theis; Bjerrum, Ole Jannik; Lund, Trine Meldgaard.

    In: British Journal of Clinical Pharmacology, Vol. 85, No. 8, 2019, p. 1829-1840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016. / Nøhr-Nielsen, Asbjørn; De Bruin, Marie Louise; Thomsen, Mikael; Pipper, Christian Bressen; Lange, Theis; Bjerrum, Ole Jannik; Lund, Trine Meldgaard.

    In: British Journal of Clinical Pharmacology, Vol. 85, No. 8, 2019, p. 1829-1840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs. / Thoefner, M. S.; Westrup, U.; Toft, N.; Bjerrum, O. J.; Berendt, M.

    In: Veterinary Journal, Vol. 246, 2019, p. 92-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2018
  7. Published

    The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain. / Kristensen, P J; Gegelashvili, G; Munro, G; Heegaard, A M; Bjerrum, O J.

    In: European Journal of Pain, Vol. 22, No. 2, 02.2018, p. 282-294.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity. / Nasser, Arafat; Møller, Anette Torvin; Hellmund, Vibe; Thorborg, Sidsel Salling; Jespersgaard, Cathrine; Bjerrum, Ole J.; Dupontd, Erik; Nachman, Gösta; Lykkesfeldt, Jens; Jensen, Troels Staehelin; Møller, Lisbeth Birk.

    In: Pain, Vol. 159, No. 6, 2018, p. 1012-1024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine. / Bjerrum, Ole Jannik; Androlyte, Monika.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 123 , No. 2, 2018, p. 155–160 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats : Does it matter? / Kristensen, P J; Heegaard, A M; Kristensen, Sara Hestehave; Jeggo, R D; Bjerrum, O J; Munro, G.

    In: European Journal of Pain, Vol. 21, No. 4, 04.2017, p. 692-704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    From Face-to-fase training to blended learning in the postgraduate program SafeSciMet - a case study. / Bjerrum, Ole Jannik; Vos, Chris; Dragovic, Sanja; Jochimsen, Marc; Dirac, Jørgen ; Foth, Heidi; Wiese, Jan.

    In: European Journal of Pharmaceutical Sciences, Vol. 96, 2017, p. III-VIII.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain : Molecular Mechanisms and Pharmacology. / Gegelashvili, Georgi; Bjerrum, Ole Jannik.

    Glial Amino Acid Transporters. Vol. 16 Springer, 2017. p. 225-253 (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  14. 2016
  15. Published

    A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science : Workshop Proceedings and Commentary. / Borup, Gitte; Bach, Karin Friis; Schmiegelow, Merete; Kildemoes, Helle Wallach; Bjerrum, Ole Jannik; Westergaard, Niels .

    In: Therapeutic Innovation & Regulatory Science, Vol. 50, No. 3, 05.2016, p. 304-311.

    Research output: Contribution to journalComment/debateResearchpeer-review

  16. 2015
  17. Published

    An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition. / Sawicki-Wrzask, Dominik; Thomsen, Mikael ; Bjerrum, Ole Jannik.

    In: Therapeutic Innovation & Regulatory Science, Vol. 49, No. 4, 2015, p. 553-559.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    High-affinity Glutamate Transporters in Pain: An Emerging and Therapeutic Target. / Gegelashvili, George; Bjerrum, Ole Jannik.

    In: Journal of Neurochemistry, Vol. 6, 2015, p. 712-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Intraplantar injection of tetrahydrobiopterin induces nociception in mice. / Nasser, Arafat; Ali, Sawsan ; Wilsbech, Signe; Bjerrum, Ole Jannik; Birk Møller, Lisbeth.

    In: Neuroscience Letters, Vol. 584, 2015, p. 247-252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The wider use of fixed-dose combinations emphasizes the need for a global approach to regulatory guideline development. / Gautam, Yvonne; Bjerrum, Ole Jannik; Schmiegelow, Merete.

    In: Therapeutic Innovation & Regulatory Science, Vol. 49, No. 1, 2015, p. 197-204.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2014
  22. Published

    Drug-drug combinations revisited. / Bjerrum, Ole Jannik; Gautam, Yvonne ; Honoré, Per Gustaf Hartvig; Vana, Vasiliki.

    In: European Journal of Hospital Pharmacy - Science and Practice, Vol. 21, No. 1, 15.01.2014, p. 8-12.

    Research output: Contribution to journalReviewResearchpeer-review

  23. 2013
  24. Published

    Measurement of sedation in rats. Comparison of the locomotor activity test, open field test and the rotarod test. / Bjerrum, Ole Jannik; Nasser, Arafat; Basnet, Anna; Merry, Ann; Kristensen, Pernille.

    2013. Poster session presented at 7th SHARE, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  25. Published

    Medicines combinations options and regulatory hurdles. / Bjerrum, Ole J; Gautam, Yvonne; Bjerrum, Esben J; Schmiegelow, Merete; Boonen, Harrie C.M.

    In: European Journal of Pharmaceutical Sciences, Vol. 49, No. 4, 16.07.2013, p. 659-63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain. / Nasser, A.; Bjerrum, Ole Jannik; Heegaard, A.-M.; Møller, Anette T.; Larsen, Majbritt; Dalbøge, Louise S.; Dupont, Erik; Jensen, Troels S.; Møller, Lisbeth B.

    In: Molecular Pain, Vol. 9, 19.02.2013, p. 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Donepezil anvendt ved neuropatisk smerte. / Bjerrum, Ole Jannik; Bjerrum, Hans J.

    In: Ugesskrift for læger, Vol. 175, No. 42, 2013, p. 2493-2494.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Donepezil as add-on to gabapentin for post-traumatic neuropathic pain : an exploratory study. / Basnet, Anna; Butler, Stephen ; Honoré, Per Gustaf Hartvig; Butler, Margareta; Gordh, Torsten E ; Kristensen, Kim K ; Bjerrum, Ole Jannik.

    In: Acta Anaesthesiologica Scandinavica, Vol. 58, No. 1, 2013, p. 61-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCi-operated rats. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Frederiksen, K.K.; Kristensen, P.; Abrahamsen, B.; Gegelashvili, G.

    2013. Poster session presented at Annual meeting of SASP and DSF, Århus, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  30. Published

    Dose-dependent effect of ceftriaxone (A beta-lactam) on mechanical pain hypersensitivity in the CCI nerve rat model. / Bjerrum, Ole Jannik; Frederiksen, K.K.; Kristensen, P. ; Abrahamsen, B.; Honoré, Per Gustaf Hartvig.

    2013. Poster session presented at Danish Society For Pharmacology , Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  31. Published

    Fixed Dose Combinations. The Physician attitude to the wider use. A pilot study. / Bjerrum, Ole Jannik; Vana, Vasiliki.

    2013. Poster session presented at 7 th SHARE, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  32. Published

    Fixed drug combinations: are current regulatory guidelines in the EU and US adequate for effectively guiding Development? / Bjerrum, Ole Jannik; Gautam, Y.; Schmiegelow, M.

    2013. Poster session presented at DIA EUROmeeting, Amsterdam, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  33. Published

    Orphan disease council - A new interdiciplinary private/public partnership promoting the Development of orphan medicinal products. / Bjerrum, Ole Jannik; Hove, H.B.; Dali, C.; Callesen, L.; Ludvig, G.; Thyregod, L.

    2013. Poster session presented at Fællesmøde for Dansk Selskab for Klinisk Farmakologi og Dansk Selskab for Farmakologi og Toksikologi, Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  34. Published

    Pain perception and Dopa Responsive Dystonia. / Bjerrum, Ole Jannik; Nasser, Arafat; Møller, A.T.; Møller, B.; Jensen, T.S.

    2013. Poster session presented at European Pain Meeting, Milano, Italy.

    Research output: Contribution to conferencePosterResearchpeer-review

  35. Published

    Promising effects of donepezil when added to patients treated with gabapentin for neuropathic pain. / Basnet, Anna; Butler, S. ; Honoré, Per Gustaf Hartvig; Butler, M.; Gordh, T.E.; Kristensen, K.; Bjerrum, Ole Jannik.

    2013. Poster session presented at Third SAPS meeting, Helsinki, Finland.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    Why medicines Combinations? Friend or Foe? / Bjerrum, Ole Jannik; Gautam, Y.; Boonen, Harrie C.M.; Schmiegelow, M.; Honoré, Per Gustaf Hartvig.

    2013. Poster session presented at Fællesmøde for Dansk Selskab for Klinisk Farmakologi og Dansk Selskab for Farmakologi og Toksikologi, Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  37. 2012
  38. Published

    Sortilins in neuropathic pain. / Richner, M; Bjerrum, O J; Koninck, Y De; Nykjaer, A; Vaegter, C B.

    In: Scandinavian Journal of Pain, Vol. 3, No. 3, 29.12.2012, p. 183-184.

    Research output: Contribution to journalConference abstract in journalResearch

  39. Published

    Blå medicin mod smerter. / Boulakou, Athanasia; Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    In: Lægemiddelforskning, Vol. 2012, 2012, p. 18-19.

    Research output: Contribution to journalJournal articleCommunication

  40. Published

    Kombinationslægemiddel reducerer bivirkningerne ved smertebehandling. / Bjerrum, Ole Jannik; Basnet, Anna; Honoré, Per Gustaf Hartvig; Gautam, Yvonne .

    In: Lægemiddelforskning, No. 1, 2012, p. 15-17.

    Research output: Contribution to journalJournal articleCommunication

  41. 2011
  42. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011. Poster session presented at Share Symposium 2010, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterCommunication

  43. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice. / Richner, Mette; Bjerrum, Ole Jannik; Nykjær, Anders; Vaegter, Christian B.

    In: Journal of Visualized Experiments, No. 54, 18.08.2011, p. e3092.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers. / Lappin, Graham ; Shishikura, Yoko; Jochemsen, Roeline; Weaver, Richard John ; Gesson, Charlotte; Houston, J. Brian ; Oosterhuis, Berend; Bjerrum, Ole Jannik; Grynkiewicz, Grzegorz; Alder, Jane; Rowland, Malcolm; Garner, Colin.

    In: European Journal of Pharmaceutical Sciences, Vol. 43, No. 3, 20.04.2011, p. 141-150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    European new safe and innovative medicines initiatives : history and progress (through December 2009). / Bjerrum, Ole Jannik; H. Linden, Hans.

    Translational medicine and drug discovery. Cambridge : Cambridge University Press, 2011. p. 265-288.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  46. Published

    Beta-lactam antibiotic as dose dependent analgesic treatment of neuropathic pain. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  47. Published

    Ceftriaxone, an EAAT-2 transporter inducer, shows antinociceptive effects in acute and neuropathic pain models. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  48. Published

    Characterization of drug combination effects in a rat model of neuropathic pain ny population modelling and simulation of response-time profiles. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  49. Published

    Combination therapy for neuropathic pain: Donepezil improves gabapentins antinoceptive effect in SNI rats. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  50. Published

    Decrease in nocifensive behaviour in rats after treatment with the EAAT-2 transporter inducer cetriaxone. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Abrahamsen, Bjarke.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  51. Published

    Development of quantitative Pharmacology Pharmacometrics in Denmark. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  52. Published

    Development of quantitative pharmacology-pharmacometrics in Denmark. / Honoré, Per Gustaf Hartvig; Bjerrum, Ole Jannik; Lund, Trine Meldgaard; Angelo, Helle; Ingwersen, Steen H; Thygesen, Peter ; Kristensen, Kim; Larsen, Frank.

    2011. Poster session presented at Danish Society of Pharmacology meeting, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  53. Published

    Effects of the excitatory amino acid transporter subtype 2(EAAT-2) inducer ceftriaxone on different pain modalities in rat. / Eljaja, Laila; Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Abrahamsen, Bjarke.

    In: Scandinavian Journal of Pain, Vol. 2, No. 3, 2011, p. 132-136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Excellence in education and training advances competitiveness of the pharmaceutical industry in Europe. / Bjerrum, Ole Jannik.

    In: European Journal of Pharmaceutical Sciences, Vol. 44, No. 2, 2011, p. 174-175.

    Research output: Contribution to journalComment/debateResearch

  55. Published

    Neuropathic pain models in the development of analgesic drugs. / Honoré, Per Gustaf Hartvig; Basnet, Anna; Eljaja, Laila; Kristensen, Pernille ; Neustrup, Lene Munkholm; Møllgaard, Pia; Bjerrum, Ole Jannik.

    In: Scandinavian Journal of Pain, Vol. 2, No. 4, 2011, p. 172-177.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Pharmacy student driven detection of adverse drug reactions in the community pharmacy setting. / Christensen, Søren Troels; Søndergaard, Birthe; Honoré, Per Hartvig; Bjerrum, Ole Jannik.

    In: Pharmacoepidemiology and Drug Safety, Vol. 20, 2011, p. 399-404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Population modelling and simulation of response - time profiles for charaterization of drug combination effect in a rat model of neuropathic pain. / Bjerrum, Ole Jannik; Basnet, Anna; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  58. Published

    Population pharmacodynamic modeling and simulation as a method to characterize drug combination effects i a rat model of neuropathic pain. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  59. Published

    Predictive validity of pharmacologic interventions in animal models of neuropathic pain. / Honoré, Per Gustaf Hartvig; Basnet, Anna; Kristensen, Pernille; Andersen, Lene Munkholm; Neustrup, Signe; Møllgaard, Pia; Eljaja, Laila; Bjerrum, Ole Jannik.

    In: Scandinavian Journal of Pain, Vol. 2, No. 4, 2011, p. 178-184.

    Research output: Contribution to journalJournal articleResearchpeer-review

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