Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor emeritus


  1. Published

    A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science : Workshop Proceedings and Commentary. / Borup, Gitte; Bach, Karin Friis; Schmiegelow, Merete; Kildemoes, Helle Wallach; Bjerrum, Ole Jannik; Westergaard, Niels .

    In: Therapeutic Innovation & Regulatory Science, Vol. 50, No. 3, 05.2016, p. 304-311.

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. Published

    A novel inhibitor of advanced glycation end- product formation inhibits mesenteric vascular hypertrophy in experimental diabetes. / Bjerrum, Ole Jannik.

    In: Diabetologica, Vol. 42, 1999, p. 472-479.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A simple method for the preparation and purification of C1 complement cleaved beta 2-microglobulin from human serum. / Nissen, Mogens Holst; Johansen, B; Bjerrum, Ole Jannik.

    In: Journal of Immunological Methods, Vol. 205, No. 1, 1997, p. 29-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011. Poster session presented at Share Symposium 2010, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterCommunication

  5. Published

    An analysis of the fixed-dose combinations authorized by the European Union, 2009-14: A Focus on benefit-risk and clinial development condition. / Sawicki-Wrzask, Dominik; Thomsen, Mikael ; Bjerrum, Ole Jannik.

    In: Therapeutic Innovation & Regulatory Science, Vol. 49, No. 4, 2015, p. 553-559.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Beta-lactam antibiotic as dose dependent analgesic treatment of neuropathic pain. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  7. Published

    Bivirkningsmonitorering af lægemidler : en ny udfordring af apoteksfarmaceuter. / Christensen, Søren Troels; Bjerrum, Ole Jannik.

    In: Lægemiddelforskning, 2009, p. 49-51.

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    Blå medicin mod smerter. / Boulakou, Athanasia; Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    In: Lægemiddelforskning, Vol. 2012, 2012, p. 18-19.

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016. / Nøhr-Nielsen, Asbjørn; De Bruin, Marie Louise; Thomsen, Mikael; Pipper, Christian Bressen; Lange, Theis; Bjerrum, Ole Jannik; Lund, Trine Meldgaard.

    In: British Journal of Clinical Pharmacology, Vol. 85, No. 8, 2019, p. 1829-1840.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Ceftriaxone, an EAAT-2 transporter inducer, shows antinociceptive effects in acute and neuropathic pain models. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  11. Published

    Centrally mediated anti-noceptive action of GABAA receptor agonists in the spared nerve injury model of neuropathic pain. / Bjerrum, Ole Jannik.

    In: European Journal of Pharmaceutical Sciences, Vol. 516, 2005, p. 131-138.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Characterization of drug combination effects in a rat model of neuropathic pain ny population modelling and simulation of response-time profiles. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  13. Published

    Co-administered gabapentin and venlafaxine in nerve injured rats : effect on mechanical hypersensitivity, motor function and pharmacokinetics. / Folkesson, Anna Jessica Maria; Honoré, Per Gustaf Hartvig; Bjerrum, Ole Jannik.

    In: Scandinavian Journal of Pain, Vol. 1, No. 2, 2009, p. 91-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Combination therapy for neuropathic pain: Donepezil improves gabapentins antinoceptive effect in SNI rats. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  15. Published

    Community pharmacies as platform for collection of real-world evidence of medicines usage explored through a pilot study: From standard T2D medication to treatment with the injectable combination product Xultophy. / Alkis, N; Nørgaard, Lotte Stig; Bjerrum, Ole Jannik.

    2019. Poster session presented at Årsmøde i Dansk Farmakologisk Selskab, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  16. Published

    Community pharmacy driven pharmacovigilance. / Bjerrum, Ole Jannik; Christensen, Søren Troels.

    2010. Poster session presented at Danish Society for Pharmacology 2nd annual meeting, Odense, Denmark.

    Research output: Contribution to conferencePosterCommunication

  17. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers. / Lappin, Graham ; Shishikura, Yoko; Jochemsen, Roeline; Weaver, Richard John ; Gesson, Charlotte; Houston, J. Brian ; Oosterhuis, Berend; Bjerrum, Ole Jannik; Grynkiewicz, Grzegorz; Alder, Jane; Rowland, Malcolm; Garner, Colin.

    In: European Journal of Pharmaceutical Sciences, Vol. 43, No. 3, 20.04.2011, p. 141-150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Decrease in nocifensive behaviour in rats after treatment with the EAAT-2 transporter inducer cetriaxone. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Abrahamsen, Bjarke.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  19. Published

    Development of quantitative Pharmacology Pharmacometrics in Denmark. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig.

    2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  20. Published

    Development of quantitative pharmacology-pharmacometrics in Denmark. / Honoré, Per Gustaf Hartvig; Bjerrum, Ole Jannik; Lund, Trine Meldgaard; Angelo, Helle; Ingwersen, Steen H; Thygesen, Peter ; Kristensen, Kim; Larsen, Frank.

    2011. Poster session presented at Danish Society of Pharmacology meeting, Odense, Denmark.

    Research output: Contribution to conferencePosterResearch

  21. Published

    Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain. / Hald, Andreas; Ding, Ming; Egerod, Kristoffer Lihme; Hansen, Rikke Rie; Konradsen, Dorthe; Jørgensen, Stine G.; Atalay, Baris; Nasser, Arafat; Bjerrum, Ole Jannik; Heegaard, Anne-Marie.

    In: Pharmacology, Biochemistry and Behavior, Vol. 91, No. 1, 2008, p. 38-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Donepezil anvendt ved neuropatisk smerte. / Bjerrum, Ole Jannik; Bjerrum, Hans J.

    In: Ugesskrift for læger, Vol. 175, No. 42, 2013, p. 2493-2494.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Donepezil as add-on to gabapentin for post-traumatic neuropathic pain : an exploratory study. / Basnet, Anna; Butler, Stephen ; Honoré, Per Gustaf Hartvig; Butler, Margareta; Gordh, Torsten E ; Kristensen, Kim K ; Bjerrum, Ole Jannik.

    In: Acta Anaesthesiologica Scandinavica, Vol. 58, No. 1, 2013, p. 61-73.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCi-operated rats. / Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Frederiksen, K.K.; Kristensen, P.; Abrahamsen, B.; Gegelashvili, G.

    2013. Poster session presented at Annual meeting of SASP and DSF, Århus, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  25. Published

    Dose-dependent effect of ceftriaxone (A beta-lactam) on mechanical pain hypersensitivity in the CCI nerve rat model. / Bjerrum, Ole Jannik; Frederiksen, K.K.; Kristensen, P. ; Abrahamsen, B.; Honoré, Per Gustaf Hartvig.

    2013. Poster session presented at Danish Society For Pharmacology , Odense, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  26. Published

    Drug-drug combinations revisited. / Bjerrum, Ole Jannik; Gautam, Yvonne ; Honoré, Per Gustaf Hartvig; Vana, Vasiliki.

    In: European Journal of Hospital Pharmacy - Science and Practice, Vol. 21, No. 1, 15.01.2014, p. 8-12.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Effect of GTP-cyclohydrolase deficiency in the HPH-1mouse on acute and inflammatory pain. / Nasser, Arafat; Bjerrum, Ole Jannik; Heegaard, Anne-Marie.

    2010. Abstract from World Congress on Pain, Montreal, Canada.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  28. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development. / Krishna, Rajesh; Schaefer, Hans Guenter; Bjerrum, Ole Jannik.

    In: European Journal of Pharmaceutical Sciences, Vol. 31, No. 1, 2007, p. 62-67.

    Research output: Contribution to journalLetterResearch

  29. Published

    Effects of the excitatory amino acid transporter subtype 2(EAAT-2) inducer ceftriaxone on different pain modalities in rat. / Eljaja, Laila; Bjerrum, Ole Jannik; Honoré, Per Gustaf Hartvig; Abrahamsen, Bjarke.

    In: Scandinavian Journal of Pain, Vol. 2, No. 3, 2011, p. 132-136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Electrophoretic and chromatographic differentiation of two forms of albumin in equilibrium at neutral pH. New screening technique of ligand binding to albumin. / Bjerrum, Ole Jannik.

    In: Electrophoresis, Vol. 16, No. 8, 1995, p. 1401-1407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    European new safe and innovative medicines initiatives : history and progress (through December 2009). / Bjerrum, Ole Jannik; H. Linden, Hans.

    Translational medicine and drug discovery. Cambridge : Cambridge University Press, 2011. p. 265-288.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  32. Published

    Excellence in education and training advances competitiveness of the pharmaceutical industry in Europe. / Bjerrum, Ole Jannik.

    In: European Journal of Pharmaceutical Sciences, Vol. 44, No. 2, 2011, p. 174-175.

    Research output: Contribution to journalComment/debateResearch

  33. Published

    Fast detection of adverse drug reactions of new drugs by community pharmacists. / Christensen, Søren Troels; Bjerrum, Ole Jannik.

    In: Drug Safety, Vol. 33, No. 10, 2010, p. 928.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Fixed Dose Combinations. The Physician attitude to the wider use. A pilot study. / Bjerrum, Ole Jannik; Vana, Vasiliki.

    2013. Poster session presented at 7 th SHARE, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  35. Published

    Fixed drug combinations: are current regulatory guidelines in the EU and US adequate for effectively guiding Development? / Bjerrum, Ole Jannik; Gautam, Y.; Schmiegelow, M.

    2013. Poster session presented at DIA EUROmeeting, Amsterdam, Netherlands.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    From Face-to-fase training to blended learning in the postgraduate program SafeSciMet - a case study. / Bjerrum, Ole Jannik; Vos, Chris; Dragovic, Sanja; Jochimsen, Marc; Dirac, Jørgen ; Foth, Heidi; Wiese, Jan.

    In: European Journal of Pharmaceutical Sciences, Vol. 96, 2017, p. III-VIII.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Genetik kan forudsige følsomhed for smerte. / Nasser, Arafat; Bjerrum, Ole Jannik; Heegaard, Anne-Marie; Møller, Lisbeth Birk.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 34-36.

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Glutamate Transport System as a Novel Therapeutic Target in Chronic Pain : Molecular Mechanisms and Pharmacology. / Gegelashvili, Georgi; Bjerrum, Ole Jannik.

    Glial Amino Acid Transporters. Vol. 16 Springer, 2017. p. 225-253 (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  39. Published

    Growth hormone releasing hexapeptide (GHRP-6)-activates the inositol (1,4,5)-Triphosphate/diacylglycerol pathway. / Bjerrum, Ole Jannik.

    In: Journal of Receptors and Signal Transduction, Vol. 15, No. 1-4, 1995, p. 311-323.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity. / Nasser, Arafat; Møller, Anette Torvin; Hellmund, Vibe; Thorborg, Sidsel Salling; Jespersgaard, Cathrine; Bjerrum, Ole J.; Dupontd, Erik; Nachman, Gösta; Lykkesfeldt, Jens; Jensen, Troels Staehelin; Møller, Lisbeth Birk.

    In: Pain, Vol. 159, No. 6, 2018, p. 1012-1024.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    High-affinity Glutamate Transporters in Pain: An Emerging and Therapeutic Target. / Gegelashvili, George; Bjerrum, Ole Jannik.

    In: Journal of Neurochemistry, Vol. 6, 2015, p. 712-30.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    How first time-in human studies are being performed; A survey of phase 1 dose escalation trials in healthy volunteers published between 1995-2004. / Bjerrum, Ole Jannik.

    In: Journal of Clinical Pharmacology, Vol. 45, 2005, p. 1123-1136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Identifying Off-label Prescriptions trough Data Mining in Danish Community Pharmacy Servers: An exploratory Study on Desmopressin, Diclofenac, Fucidin, Mirtazapine and Quetiapine. / Bjerrum, Ole Jannik; Androlyte, Monika.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 123 , No. 2, 2018, p. 155–160 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Immunochemically identical hydrophilic and amphiphilic forms of the bovine adrenomedullary dopamine beta-hydroxylase. / Bjerrum, Ole Jannik; Helle, K B; Bock, Elisabeth Marianne.

    In: Biochemical Journal, Vol. 181, No. 1, 1979, p. 231-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain. / Nasser, A.; Bjerrum, Ole Jannik; Heegaard, A.-M.; Møller, Anette T.; Larsen, Majbritt; Dalbøge, Louise S.; Dupont, Erik; Jensen, Troels S.; Møller, Lisbeth B.

    In: Molecular Pain, Vol. 9, 19.02.2013, p. 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Intraplantar injection of tetrahydrobiopterin induces nociception in mice. / Nasser, Arafat; Ali, Sawsan ; Wilsbech, Signe; Bjerrum, Ole Jannik; Birk Møller, Lisbeth.

    In: Neuroscience Letters, Vol. 584, 2015, p. 247-252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Kombinationslægemiddel reducerer bivirkningerne ved smertebehandling. / Bjerrum, Ole Jannik; Basnet, Anna; Honoré, Per Gustaf Hartvig; Gautam, Yvonne .

    In: Lægemiddelforskning, No. 1, 2012, p. 15-17.

    Research output: Contribution to journalJournal articleCommunication

  48. Published

    Low dose of donepezil improves gabapentin analgesia in the rat spared nerve injury model of neuropathic pain : single and multiple dosing studies. / Folkesson, Anna; Honoré, Per Hartvig; Andersen, Lene Munkholm; Kristensen, Pernille Juul; Bjerrum, Ole Jannik.

    In: Journal of Neural Transmission, Vol. 117, 2010, p. 1377-1385.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Measurement of sedation in rats. Comparison of the locomotor activity test, open field test and the rotarod test. / Bjerrum, Ole Jannik; Nasser, Arafat; Basnet, Anna; Merry, Ann; Kristensen, Pernille.

    2013. Poster session presented at 7th SHARE, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  50. Published

    Mechanical sensory threshold in Cavalier King Charles spaniels with syringomyelia-associated scratching and control dogs. / Thoefner, M. S.; Westrup, U.; Toft, N.; Bjerrum, O. J.; Berendt, M.

    In: Veterinary Journal, Vol. 246, 2019, p. 92-97.

    Research output: Contribution to journalJournal articleResearchpeer-review

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