Patrick Ryan Gentry

Patrick Ryan Gentry

Postdoc


  1. 2010
  2. Chemical lead optimization of a pan G(q) mAChR M(1), M(3), M(5) positive allosteric modulator (PAM) lead. Part I : Development of the first highly selective M(5) PAM. / Bridges, Thomas M; Kennedy, J Phillip; Cho, Hyekyung P; Breininger, Micah L; Gentry, Patrick R; Hopkins, Corey R; Conn, P Jeffrey; Lindsley, Craig W.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 20, No. 2, 15.01.2010, p. 558-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2009
  4. Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor. / Kennedy, J Phillip; Bridges, Thomas M; Gentry, Patrick R; Brogan, John T; Kane, Alexander S; Jones, Carrie K; Brady, Ashley E; Shirey, Jana K; Conn, P Jeffrey; Lindsley, Craig W.

    In: ChemMedChem, Vol. 4, No. 10, 10.2009, p. 1600-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4). / Williams, Richard; Johnson, Kari A; Gentry, Patrick R; Niswender, Colleen M; Weaver, Charles D; Conn, P Jeffrey; Lindsley, Craig W; Hopkins, Corey R.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 19, No. 17, 01.09.2009, p. 4967-70.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins. / Bridges, Thomas M; Marlo, Joy E; Niswender, Colleen M; Jones, Carrie K; Jadhav, Satyawan B; Gentry, Patrick R; Plumley, Hyekyung C; Weaver, C David; Conn, P Jeffrey; Lindsley, Craig W.

    In: Journal of Medicinal Chemistry, Vol. 52, No. 11, 11.06.2009, p. 3445-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2008
  8. Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in rats. / Brady, Ashley E; Jones, Carrie K; Bridges, Thomas M; Kennedy, J Phillip; Thompson, Analisa D; Heiman, Justin U; Breininger, Micah L; Gentry, Patrick R; Yin, Huiyong; Jadhav, Satyawan B; Shirey, Jana K; Conn, P Jeffrey; Lindsley, Craig W.

    In: The Journal of Pharmacology and Experimental Therapeutics, Vol. 327, No. 3, 12.2008, p. 941-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I : Exploration of alternative benzyl and privileged structure moieties. / Bridges, Thomas M; Brady, Ashley E; Kennedy, J Phillip; Daniels, R Nathan; Miller, Nicole R; Kim, Kwango; Breininger, Micah L; Gentry, Patrick R; Brogan, John T; Jones, Carrie K; Conn, P Jeffrey; Lindsley, Craig W.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 18, No. 20, 15.10.2008, p. 5439-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

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