Patrick Ryan Gentry

Patrick Ryan Gentry

Postdoc


  1. Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)-selective M5-orthosteric antagonist, VU0488130 (ML381) : a novel molecular probe. / Gentry, Patrick R; Kokubo, Masaya; Bridges, Thomas M; Cho, Hyekyung P; Smith, Emery; Chase, Peter; Hodder, Peter S; Utley, Thomas J; Rajapakse, Anuruddha; Byers, Frank; Niswender, Colleen M; Morrison, Ryan D; Daniels, J Scott; Wood, Michael R; Conn, P Jeffrey; Lindsley, Craig W.

    In: ChemMedChem, Vol. 9, No. 8, 08.2014, p. 1677-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Drugs for allosteric sites on receptors. / Wenthur, Cody J; Gentry, Patrick R; Mathews, Thomas P; Lindsley, Craig W.

    In: Annual Review of Pharmacology and Toxicology, Vol. 54, 2014, p. 165-84.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Further optimization of the M5 NAM MLPCN probe ML375 : tactics and challenges. / Kurata, Haruto; Gentry, Patrick R; Kokubo, Masaya; Cho, Hyekyung P; Bridges, Thomas M; Niswender, Colleen M; Byers, Frank W; Wood, Michael R; Daniels, J Scott; Conn, P Jeffrey; Lindsley, Craig W.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 25, No. 3, 01.02.2015, p. 690-4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification of a novel scaffold for a small molecule GPR139 receptor agonist. / Nøhr, Anne Cathrine; Shehata, Mohamed A; Palmer, Daniel; Pokhrel, Rina; Vallianou, Maria; Foster, Simon R; Gentry, Patrick R; Gloriam, David E; Bräuner-Osborne, Hans.

    In: Scientific Reports, Vol. 9, No. 1, 07.03.2019, p. 3802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors. / Hao, Jijun; Ho, Joshua N; Lewis, Jana A; Karim, Kaleh A; Daniels, R Nathan; Gentry, Patrick R; Hopkins, Corey R; Lindsley, Craig W; Hong, Charles C.

    In: ACS chemical biology, Vol. 5, No. 2, 19.02.2010, p. 245-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137 : continued optimization of an MLPCN probe molecule. / Melancon, Bruce J; Poslusney, Michael S; Gentry, Patrick R; Tarr, James C; Sheffler, Douglas J; Mattmann, Margrith E; Bridges, Thomas M; Utley, Thomas J; Daniels, J Scott; Niswender, Colleen M; Conn, P Jeffrey; Lindsley, Craig W; Wood, Michael R.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 23, No. 2, 15.01.2013, p. 412-6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. / Foster, Daniel J; Gentry, Patrick R; Lizardi-Ortiz, Jose E; Bridges, Thomas M; Wood, Michael R; Niswender, Colleen M; Sulzer, David; Lindsley, Craig W; Xiang, Zixiu; Conn, P Jeffrey.

    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, No. 9, 26.02.2014, p. 3253-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. MGluR4 allosteric potentiators and their preparation, compositions, and methods of treating neurological dysfunction. / Conn, P Jeffrey (Inventor); Lindsley, Craig W (Inventor); Hopkins, Corey R (Inventor); Weaver, David (Inventor); Niswender, Colleen M (Inventor); Engers, Darren W (Inventor); Gentry, Patrick Ryan (Inventor); Cheung, Yiu-Yin (Inventor); Salovich, James (Inventor); Gogliotti, Rocco D (Inventor).

    Patent No.: US20120245153A1. Sep 04, 2010.

    Research output: PatentResearch

  9. Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators. / Berizzi, Alice E; Gentry, Patrick R; Rueda, Patricia; Den Hoedt, Sandra; Sexton, Patrick M; Langmead, Christopher J; Christopoulos, Arthur.

    In: Molecular Pharmacology, Vol. 90, No. 4, 10.2016, p. 427-36.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 172786299