Patrick Ryan Gentry
Patrick Ryan Gentry

Postdoc


  1. Synthesis and structure-activity relationships of allosteric potentiators of the m(4) muscarinic acetylcholine receptor

    Kennedy, J. P., Bridges, T. M., Gentry, Patrick Ryan, Brogan, J. T., Kane, A. S., Jones, C. K., Brady, A. E., Shirey, J. K., Conn, P. J. & Lindsley, C. W., Oct 2009, In : ChemMedChem. 4, 10, p. 1600-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)

    Engers, D. W., Gentry, Patrick Ryan, Williams, R., Bolinger, J. D., Weaver, C. D., Menon, U. N., Conn, P. J., Lindsley, C. W., Niswender, C. M. & Hopkins, C. R., 1 Sep 2010, In : Bioorganic & Medicinal Chemistry Letters. 20, 17, p. 5175-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties

    Bridges, T. M., Brady, A. E., Kennedy, J. P., Daniels, R. N., Miller, N. R., Kim, K., Breininger, M. L., Gentry, Patrick Ryan, Brogan, J. T., Jones, C. K., Conn, P. J. & Lindsley, C. W., 15 Oct 2008, In : Bioorganic & Medicinal Chemistry Letters. 18, 20, p. 5439-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)

    Williams, R., Johnson, K. A., Gentry, Patrick Ryan, Niswender, C. M., Weaver, C. D., Conn, P. J., Lindsley, C. W. & Hopkins, C. R., 1 Sep 2009, In : Bioorganic & Medicinal Chemistry Letters. 19, 17, p. 4967-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: the continued optimization of an MLPCN probe molecule

    Poslusney, M. S., Melancon, B. J., Gentry, Patrick Ryan, Sheffler, D. J., Bridges, T. M., Utley, T. J., Daniels, J. S., Niswender, C. M., Conn, P. J., Lindsley, C. W. & Wood, M. R., 15 Mar 2013, In : Bioorganic & Medicinal Chemistry Letters. 23, 6, p. 1860-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Novel Allosteric Modulators of G Protein-coupled Receptors

    Gentry, Patrick Ryan, Sexton, P. M. & Christopoulos, A., 7 Aug 2015, In : The Journal of Biological Chemistry. 290, 32, p. 19478-88 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric Modulators

    Berizzi, A. E., Gentry, Patrick Ryan, Rueda, P., Den Hoedt, S., Sexton, P. M., Langmead, C. J. & Christopoulos, A., Oct 2016, In : Molecular Pharmacology. 90, 4, p. 427-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. MGluR4 allosteric potentiators and their preparation, compositions, and methods of treating neurological dysfunction

    Conn, P. J., Lindsley, C. W., Hopkins, C. R., Weaver, D., Niswender, C. M., Engers, D. W., Gentry, Patrick Ryan, Cheung, Y., Salovich, J. & Gogliotti, R. D., 27 Sep 2012, Patent No. US20120245153A1, 4 Sep 2010

    Research output: Patent

  9. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location

    Foster, D. J., Gentry, Patrick Ryan, Lizardi-Ortiz, J. E., Bridges, T. M., Wood, M. R., Niswender, C. M., Sulzer, D., Lindsley, C. W., Xiang, Z. & Conn, P. J., 26 Feb 2014, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 9, p. 3253-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Isatin replacements applied to the highly selective, muscarinic M1 PAM ML137: continued optimization of an MLPCN probe molecule

    Melancon, B. J., Poslusney, M. S., Gentry, Patrick Ryan, Tarr, J. C., Sheffler, D. J., Mattmann, M. E., Bridges, T. M., Utley, T. J., Daniels, J. S., Niswender, C. M., Conn, P. J., Lindsley, C. W. & Wood, M. R., 15 Jan 2013, In : Bioorganic & Medicinal Chemistry Letters. 23, 2, p. 412-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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