Patrick Ryan Gentry

Patrick Ryan Gentry

Postdoc


  1. Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure : 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380). / Gentry, Patrick R; Kokubo, Masaya; Bridges, Thomas M; Noetzel, Meredith J; Cho, Hyekyung P; Lamsal, Atin; Smith, Emery; Chase, Peter; Hodder, Peter S; Niswender, Colleen M; Daniels, J Scott; Conn, P Jeffrey; Lindsley, Craig W; Wood, Michael R.

    In: Journal of Medicinal Chemistry, Vol. 57, No. 18, 25.09.2014, p. 7804-10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379) : a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM). / Morris, Lindsey C; Nance, Kellie D; Gentry, Patrick R; Days, Emily L; Weaver, C David; Niswender, Colleen M; Thompson, Analisa D; Jones, Carrie K; Locuson, Chuck W; Morrison, Ryan D; Daniels, J Scott; Niswender, Kevin D; Lindsley, Craig W.

    In: Journal of Medicinal Chemistry, Vol. 57, No. 23, 11.12.2014, p. 10192-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)-selective M5-orthosteric antagonist, VU0488130 (ML381) : a novel molecular probe. / Gentry, Patrick R; Kokubo, Masaya; Bridges, Thomas M; Cho, Hyekyung P; Smith, Emery; Chase, Peter; Hodder, Peter S; Utley, Thomas J; Rajapakse, Anuruddha; Byers, Frank; Niswender, Colleen M; Morrison, Ryan D; Daniels, J Scott; Wood, Michael R; Conn, P Jeffrey; Lindsley, Craig W.

    In: ChemMedChem, Vol. 9, No. 8, 08.2014, p. 1677-82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Drugs for allosteric sites on receptors. / Wenthur, Cody J; Gentry, Patrick R; Mathews, Thomas P; Lindsley, Craig W.

    In: Annual Review of Pharmacology and Toxicology, Vol. 54, 2014, p. 165-84.

    Research output: Contribution to journalReviewResearchpeer-review

  5. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location. / Foster, Daniel J; Gentry, Patrick R; Lizardi-Ortiz, Jose E; Bridges, Thomas M; Wood, Michael R; Niswender, Colleen M; Sulzer, David; Lindsley, Craig W; Xiang, Zixiu; Conn, P Jeffrey.

    In: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, No. 9, 26.02.2014, p. 3253-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 172786299