Patrick Ryan Gentry
Patrick Ryan Gentry

Postdoc


  1. M5 receptor activation produces opposing physiological outcomes in dopamine neurons depending on the receptor's location

    Foster, D. J., Gentry, Patrick Ryan, Lizardi-Ortiz, J. E., Bridges, T. M., Wood, M. R., Niswender, C. M., Sulzer, D., Lindsley, C. W., Xiang, Z. & Conn, P. J., 26 Feb 2014, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 9, p. 3253-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380)

    Gentry, Patrick Ryan, Kokubo, M., Bridges, T. M., Noetzel, M. J., Cho, H. P., Lamsal, A., Smith, E., Chase, P., Hodder, P. S., Niswender, C. M., Daniels, J. S., Conn, P. J., Lindsley, C. W. & Wood, M. R., 25 Sep 2014, In : Journal of Medicinal Chemistry. 57, 18, p. 7804-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)-selective M5-orthosteric antagonist, VU0488130 (ML381): a novel molecular probe

    Gentry, Patrick Ryan, Kokubo, M., Bridges, T. M., Cho, H. P., Smith, E., Chase, P., Hodder, P. S., Utley, T. J., Rajapakse, A., Byers, F., Niswender, C. M., Morrison, R. D., Daniels, J. S., Wood, M. R., Conn, P. J. & Lindsley, C. W., Aug 2014, In : ChemMedChem. 9, 8, p. 1677-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM)

    Morris, L. C., Nance, K. D., Gentry, Patrick Ryan, Days, E. L., Weaver, C. D., Niswender, C. M., Thompson, A. D., Jones, C. K., Locuson, C. W., Morrison, R. D., Daniels, J. S., Niswender, K. D. & Lindsley, C. W., 11 Dec 2014, In : Journal of Medicinal Chemistry. 57, 23, p. 10192-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Drugs for allosteric sites on receptors

    Wenthur, C. J., Gentry, Patrick Ryan, Mathews, T. P. & Lindsley, C. W., 2014, In : Annual Review of Pharmacology and Toxicology. 54, p. 165-84 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 172786299