Employees – University of Copenhagen

Petrine Wellendorph

Petrine Wellendorph

Associate Professor


  1. 2019
  2. Published

    Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites. / Krall, Jacob; Bavo, Francesco; Falk-Petersen, Christina B; Jensen, Claus Hatt; Nielsen, Julie Olsson; Tian, Yongsong; Anglani, Valeria; Kongstad, Kenneth Thermann; Piilgaard, Louise; Nielsen, Birgitte; Gloriam, David E; Kehler, Jan; Jensen, Anders; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 62, No. 5, 14.03.2019, p. 2798-2813.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets. / Griem-Krey, Nane; Klein, Anders Bue; Herth, Matthias; Wellendorph, Petrine.

    In: Journal of visualized experiments : JoVE, No. 145, 12.03.2019.

    Research output: Contribution to journalJournal articleCommunication

  4. 2018
  5. Published

    Synthesis, pharmacological activity and molecular modeling studies of a series of 2-amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid analogues as betaine/GABA transporter 1 (BGT1) substrate-inhibitors. / Kickinger, Stefanie; Al-Khawaja, Anas; Haugaard, Anne Staehr; Loeffler, Rebekka; Damgaard, Maria; Eckert, Gerhard; Frolund, Bente; Wellendorph, Petrine.

    2018. Abstract from 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  6. Published

    Inhibition of GABA transporters fails to afford significant protection following focal cerebral ischemia. / Lie, Maria Ek; Gowing, Emma K; Clausen, Rasmus P; Wellendorph, Petrine; Clarkson, Andrew N.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 38, No. 1, 2018, p. 166-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pharmacological Characterization of [3H]ATPCA as a Substrate for Studying the Functional Role of the Betaine/GABA Transporter 1 and the Creatine Transporter. / Al-Khawaja, Anas; Haugaard, Anne S; Marek, Ales; Löffler, Rebekka; Thiesen, Louise; Santiveri, Monica; Damgaard, Maria; Bundgaard, Christoffer; Frølund, Bente; Wellendorph, Petrine.

    In: A C S Chemical Neuroscience, Vol. 9, No. 3, 2018, p. 545–554.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    GAT3 selective substrate l-isoserine upregulates GAT3 expression and increases functional recovery after a focal ischemic stroke in mice. / Lie, Maria Ek; Gowing, Emma K; Johansen, Nina B; Dalby, Nils Ole; Thiesen, Louise; Wellendorph, Petrine; Clarkson, Andrew N.

    In: Journal of Cerebral Blood Flow and Metabolism, 21.11.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1). / Jørgensen, Lars; Al-Khawaja, Anas; Kickinger, Stefanie; Vogensen, Stine B; Skovgaard-Petersen, Jonas; Rosenthal, Emil; Borkar, Nrupa; Löffler, Rebekka; Madsen, Karsten K; Bräuner-Osborne, Hans; Schousboe, Arne; Ecker, Gerhard F; Wellendorph, Petrine; Clausen, Rasmus P.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 21, 09.10.2017, p. 8834-8846.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Development of a Robust Mammalian Cell-based Assay for Studying Recombinant α4 β1/3 δ GABAA Receptor Subtypes. / Falk-Petersen, Christina B; Søgaard, Rikke; Madsen, Kenneth L; Klein, Anders B; Frølund, Bente; Wellendorph, Petrine.

    In: Basic & Clinical Pharmacology & Toxicology, Vol. 121, No. 2, 08.2017, p. 119-129.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method. / Frandsen, Ida Osborn; Boesgaard, Michael W; Fidom, Kimberley; Hauser, Alexander S; Isberg, Vignir; Bräuner-Osborne, Hans; Wellendorph, Petrine; Gloriam, David E.

    In: Scientific Reports, Vol. 7, No. 1, 4829, 06.07.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Monastrol, a 3,4-dihydropyrimidin-2(1H)-thione, as structural scaffold for the development of modulators for GHB high-affinity binding sites and α1β2δ GABAA receptors. / Damgaard, Maria; Al-Khawaja, Anas; Nittegaard-Nielsen, Mia; Petersen, Rebekka F; Wellendorph, Petrine; Frølund, Bente.

    In: European Journal of Medicinal Chemistry, Vol. 138, 15.06.2017, p. 300-312.

    Research output: Contribution to journalJournal articleResearchpeer-review

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