Signe Lykke Nielsen
Signe Lykke Nielsen

bioanalyst

  • Molecular and Cellular Pharmacology

    Jagtvej 160, 2100 København Ø

    Phone: +45 35 33 10 37Mobile: +45 23 26 76 63

Publication year:
  1. 2016
  2. Published

    Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines

    Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, Julie Boertmann, Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, Signe Lykke, Stougaard, M., Knudsen, B. R., Moreira, José, Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, Nils, Rasmussen, A. S. & Stenvang, Jan, 22 Jan 2016, In : B M C Cancer. 16, 13 p., 34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification

    Tarpgaard, L. S., Qvortrup, C., Nygård, S. B., Nielsen, Signe Lykke, Andersen, D. R., Jensen, N. F., Stenvang, Jan, Detlefsen, S., Brünner, Nils & Pfeiffer, P., 2016, In : B M C Cancer. 16, 5 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer

    Nygård, S. B., Vainer, B., Nielsen, Signe Lykke, Bosman, F. T., Tejpar, S., Roth, A., Delorenzi, M., Brünner, Nils & Budinska, E., 2016, In : Clinical Cancer Research. 22, 7, p. 1621-1631

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2015
  6. Published

    Topoisomerase-1 gene copy aberrations are frequent in patients with breast cancer

    Kümler, I., Balslev, E., Poulsen, T. S., Nielsen, Signe Lykke, Nygård, S. B., Rømer, M. U., Christensen, I. J., Høgdall, E., Moreira, José, Nielsen, Dorte Lisbet, Brünner, Nils & Stenvang, Jan, 8 Apr 2015, In : International Journal of Cancer. 137, 8, p. 2000-2006 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2014
  8. Published

    MYC translocation partner gene determines survival of patients with large B-cell lymphoma with MYC- or double-hit MYC/BCL2 translocations

    Pedersen, M. Ø., Gang, A. O., Poulsen, T. S., Knudsen, H., Lauritzen, A. F., Nielsen, Signe Lykke, Klausen, T. W. & Nørgaard, P., Jan 2014, In : European Journal of Haematology. 92, 1, p. 42-48 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Assessment of the topoisomerase I gene copy number as a predictive biomarker of objective response to irinotecan in metastatic colorectal cancer

    Nygård, S. B., Christensen, I. J., Nielsen, Signe Lykke, phw435, phw435, Brünner, Nils & Spindler, K. G., 2014, In : Scandinavian Journal of Gastroenterology. 49, 1, p. 84-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2013
  11. Published

    Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

    Rømer, M. U. K., Nygård, S. B., Christensen, I. J., Nielsen, Signe Lykke, Nielsen, K. V., Müller, S., Smith, D. H., Vainer, B., phw435, phw435 & Brünner, Nils, 2013, In : Molecular Oncology. 7, 1, p. 101-111 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer

    Nygård, S. B., Christensen, I. J., Smith, D. H., Nielsen, Signe Lykke, Jensen, N. F., Nielsen, H. J., Vainer, B. & Brünner, Nils, 2013, In : Scandinavian Journal of Gastroenterology. 48, 12, p. 1436-1443 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2012
  14. Published

    TOP1 gene copy number and TOP1/CEN-20 ratio in stage III colorectal cancer samples

    Rømer, M. U. K., Nygård, S. B., Christensen, I. J., Hersi Smith, D., Vang Nielsen, K., Müller, S., Vainer, B., phw435, phw435, Nielsen, Signe Lykke & Brünner, Nils, 27 Apr 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  15. Published

    TOP1 gene copy numbers in colorectal cancer samples and cell lines and their association to in vitro drug sensitivity

    Rømer, M. U., Jensen, N. F., Nielsen, Signe Lykke, Müller, S., Nielsen, K. V., phw435, phw435 & Brünner, Nils, 2012, In : Scandinavian Journal of Gastroenterology. 47, 1, p. 68-79 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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