Thor Seneca Thorsen

Thor Seneca Thorsen

Assistant professor


  1. 2019
  2. Published

    Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets. / Erlendsson, Simon; Thorsen, Thor Seneca; Vauquelin, Georges; Ammendrup-Johnsen, Ina; Wirth, Volker; Martinez, Karen L.; Teilum, Kaare; Gether, Ulrik; Madsen, Kenneth Lindegaard.

    In: eLife, Vol. 8, e39180, 2019, p. 1-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2018
  4. Published

    Small-angle neutron scattering studies on the AMPA receptor GluA2 in the resting, AMPA-bound and GYKI-53655-bound states. / Larsen, Andreas Haahr; Dorosz, Jerzy; Thorsen, Thor Seneca; Johansen, Nicolai Tidemand; Darwish, Tamim; Midtgaard, Soren Roi; Arleth, Lise; Kastrup, Jette Sandholm.

    In: IUCrJ, Vol. 5, 11.2018, p. 780-793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering. / Midtgaard, Søren Roi; Darwish, Tamim A; Pedersen, Martin Cramer; Huda, Pie; Larsen, Andreas Haahr; Jensen, Grethe Vestergaard; Kynde, Søren Andreas Røssell; Skar-Gislinge, Nicholas; Nielsen, Agnieszka Janina Zygadlo; Olesen, Claus; Blaise, Mickael; Dorosz, Jerzy Jòzef; Thorsen, Thor Seneca; Venskutonytė, Raminta; Krintel, Christian; Møller, Jesper V.; Frielinghaus, Henrich; Gilbert, Elliot Paul; Martel, Anne; Kastrup, Jette Sandholm Jensen; Jensen, Poul Erik; Nissen, Poul; Arleth, Lise.

    In: F E B S Journal, Vol. 285, No. 2, 2018, p. 357-371.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2017
  7. Published

    Structure and affinity of two bicyclic glutamate analogues at AMPA and kainate receptors. / Møllerud, Stine; Pinto, Andrea; Marconi, Laura; Frydenvang, Karla Andrea; Thorsen, Thor Seneca; Laulumaa, Saara Kaisa; Venskutonyte, Raminta; Winther, Nikolaj; Cunado Moral, Ana Maria; Tamborini, Lucia; Conti, Paola; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: A C S Chemical Neuroscience, Vol. 8, No. 9, 2017, p. 2056-2064.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2015
  9. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering. / Karlsen, Morten L.; Thorsen, Thor S.; Johner, Niklaus; Ammendrup-Johnsen, Ina; Erlendsson, Simon; Tian, Xinsheng; Simonsen, Jens B.; Hoiberg-Nielsen, Rasmus; Christensen, Nikolaj M.; Khelashvili, George; Streicher, Werner; Teilum, Kaare; Vestergaard, Bente; Weinstein, Harel; Gether, Ulrik; Arleth, Lise; Madsen, Kenneth L.

    In: Structure, Vol. 23, No. 7, 07.07.2015, p. 1258-1270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2012
  11. Published

    Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway. / Madsen, Kenneth Lindegaard; Thorsen, Thor Seneca; Rahbek-Clemmensen, Troels; Eriksen, Jacob Møller; Gether, Ulrik.

    In: The Journal of Biological Chemistry, Vol. 287, No. 15, 06.04.2012, p. 12293-308.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding. / Ammendrup-Johnsen, Ina; Thorsen, Thor Seneca; Gether, Ulrik; Madsen, Kenneth Lindegaard.

    In: Biochemistry, Vol. 51, No. 2, 17.01.2012, p. 586-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2011
  14. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain. / Thorsen, Thor S; Madsen, Kenneth L; Dyhring, Tino; Bach, Anders; Peters, Dan; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 7, 01.08.2011, p. 590-600.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2010
  16. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. / Thorsen, Thor S; Madsen, Kenneth L; Rebola, Nelson; Rathje, Mette; Anggono, Victor; Bach, Anders; Moreira, Irina S; Stuhr-Hansen, Nicolai; Dyhring, Tino; Peters, Dan; Beuming, Thijs; Huganir, Richard; Weinstein, Harel; Mulle, Christophe; Strømgaard, Kristian; Rønn, Lars Christian B; Gether, Ulrik.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 107, No. 1, 2010, p. 413-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1. / Bach, Anders; Stuhr-Hansen, Nicolai; Thorsen, Thor S; Bork, Nicolai; Moreira, Irina S; Frydenvang, Karla; Padrah, Shahrokh; Christensen, S Brøgger; Madsen, Kenneth L; Weinstein, Harel; Gether, Ulrik; Strømgaard, Kristian.

    In: Organic & Biomolecular Chemistry, Vol. 8, No. 19, 2010, p. 4281-4288.

    Research output: Contribution to journalJournal articleResearchpeer-review

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