Tommy Nørskov Johansen
Tommy Nørskov Johansen

Associate Professor / Head of Studies


  1. 1994
  2. Published

    Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands

    Johansen, Tommy Nørskov, Frydenvang, Karla Andrea, Ebert, B., Krogsgaard-Larsen, Povl & Madsen, Ulf, 1994, In : Journal of Medicinal Chemistry. 37, 20, p. 3252-62 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1996
  4. Published

    N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid

    Madsen, Ulf, Frydenvang, Karla Andrea, Ebert, B., Johansen, Tommy Nørskov, Brehm, L. & Krogsgaard-Larsen, Povl, 1996, In : Journal of Medicinal Chemistry. 39, 1, p. 183-90 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

    Krogsgaard-Larsen, Povl, Ebert, B., Lund, Trine Meldgaard, Bräuner-Osborne, Hans, Sloøk, F. A., Johansen, Tommy Nørskov, Brehm, L. & Madsen, Ulf, 10 Sep 1996, In : European Journal of Medicinal Chemistry. 31, 7-8, p. 515-537 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 1997
  7. Published
  8. Published

    Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors

    Bräuner-Osborne, Hans, Nielsen, Birgitte, Stensbøl, T. B., Johansen, Tommy Nørskov, Skjaerbaek, N. & Krogsgaard-Larsen, Povl, 24 Sep 1997, In : European Journal of Pharmacology. 335, 2-3, p. R1-3

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors

    Ahmadian, H., Nielsen, Birgitte, Bräuner-Osborne, Hans, Johansen, Tommy Nørskov, Stensbøl, T. B., Sløk, F. A., Sekiyama, N., Nakanishi, S., Krogsgaard-Larsen, Povl & Madsen, Ulf, 24 Oct 1997, In : Journal of Medicinal Chemistry. 40, 22, p. 3700-5

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 1998
  11. Published

    Aryl and cycloalkyl analogues of AMPA: synthetic, pharmacological and stereochemical aspects

    Skjærbæk, N., Brehm, L., Johansen, Tommy Nørskov, Hansen, L. M., Nielsen, Birgitte, Ebert, B., Søby, K., Stensbøl, T. B., Falch, E. & Krogsgaard-Larsen, Povl, 1998, In : Bioorganic & Medicinal Chemistry. 6, 1, p. 119-131 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Heteroaryl analogues of AMPA. 2. Synthesis, absolute stereochemistry, photochemistry, and structure-activity relationships

    Falch, E., Brehm, L., Mikkelsen, I., Johansen, Tommy Nørskov, Skjærbæk, N., Nielsen, Birgitte, Stensbøl, T. B., Ebert, B. & Krogsgaard-Larsen, Povl, 1998, In : Journal of Medicinal Chemistry. 41, p. 2513-2523 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid

    Johansen, Tommy Nørskov, Ebert, B., Bräuner-Osborne, Hans, Didriksen, M., Christensen, I. T., Søby, K. K., Madsen, Ulf, Krogsgaard-Larsen, Povl & Brehm, L., 12 Mar 1998, In : Journal of Medicinal Chemistry. 41, 6, p. 930-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 1999
  15. Published

    Synthesis and Pharmacology of the Baclofen Homologues. 5-Amino-4-(4-chlorophenyl)pentanoic Acid and the R- and S-Enantiomers of 5-Amino-3-(4-chlorophenyl)pentanoic Acid

    Karla, R., Ebert, B., Thorkildsen, C., Herdeis, C., Johansen, Tommy Nørskov, Nielsen, Birgitte & Krogsgaard-Larsen, Povl, 1999, In : Journal of Medicinal Chemistry. 42, p. 2053-2059 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    3-pyrazolone analogues of the 3-isoxazolol metabotropic excitatory amino acid receptor agonist homo-AMPA. Synthesis and pharmacological testing

    Zimmermann, D., Janin, Y. L., Brehm, L., Bräuner-Osborne, Hans, Ebert, B., Johansen, Tommy Nørskov, Madsen, Ulf & Krogsgaard-Larsen, Povl, 1 Nov 1999, In : European Journal of Medicinal Chemistry. 34, 11, p. 967-976

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2000
  18. Published

    Resolution, configurational assignment, and enantiopharmacology of 2-amino-3-[3-hydroxy-5-(2-methyl-2H- tetrazol-5-yl)isoxazol-4-yl]propionic acid, a potent GluR3- and GluR4-preferring AMPA receptor agonist

    Vogensen, S. B., Jensen, H. S., Stensbøl, T. B., Frydenvang, Karla Andrea, Bang-Andersen, B., Johansen, Tommy Nørskov, Egebjerg, J. & Krogsgaard-Larsen, Povl, 2000, In : Chirality. 12, 10, p. 705-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A new structural class of subtype-selective inhibitor of cloned excitatory amino acid transporter, EAAT2

    Bräuner-Osborne, Hans, Hermit, M. B., Nielsen, Birgitte, Krogsgaard-Larsen, Povl & Johansen, Tommy Nørskov, 6 Oct 2000, In : European Journal of Pharmacology. 406, 1, p. 41-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2001
  21. Published
  22. Published

    Stereochemistry and molecular pharmacology of (S)-thio-ATPA, a new potent and selective GluR5 agonist

    Stensbøl, T. B., Jensen, H. S., Nielsen, Birgitte, Johansen, Tommy Nørskov, Egebjerg, J., Frydenvang, Karla Andrea & Krogsgaard-Larsen, Povl, 2001, In : European Journal of Pharmacology. 411, 3, p. 245-53 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Structural and stereochemical requirements for activation and blocade of excitatory amino acid receptors

    Sløk, F. A., Bräuner-Osborne, Hans, Stensbøl, T. B., Johansen, Tommy Nørskov, Ebert, B., Mortensen, M., Nielsen, Birgitte, Madsen, Ulf, Brehm, L., Falch, E. & Krogsgaard-Larsen, Povl, 2001, Medicinal Chemistry into the Millenium. Campbell, M. M. & Blagbrough, I. S. (eds.). UK: Royal Society of Chemistry, p. 52-64 13 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  24. Published

    Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors

    Madsen, Ulf, Bräuner-Osborne, Hans, Frydenvang, Karla Andrea, Hvene, L., Johansen, Tommy Nørskov, Nielsen, Birgitte, Sánchez, C., Stensbøl, T. B., Bischoff, F. & Krogsgaard-Larsen, Povl, 2001, In : Journal of Medicinal Chemistry. 44, 7, p. 1051-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Synthesis and receptor binding affinity of new selective GluR5 ligands

    Bunch, Lennart, Johansen, T. H., Bräuner-Osborne, Hans, Stensbøl, T. B., Johansen, Tommy Nørskov, Krogsgaard-Larsen, Povl & Madsen, Ulf, Apr 2001, In : Bioorganic & Medicinal Chemistry. 9, 4, p. 875-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2002
  27. Published

    2-Amino-3-(3-hydroxy-1,2,5-thiadiazol-4-yl)propionic acid: resolution, absolute stereochemistry and enantiopharmacology at glutamate receptors

    Johansen, Tommy Nørskov, Janin, Y. L., Nielsen, Birgitte, Frydenvang, Karla Andrea, Bräuner-Osborne, Hans, Stensbøl, T. B., Vogensen, S. B., Madsen, Ulf & Krogsgaard-Larsen, Povl, 2002, In : Bioorganic & Medicinal Chemistry. 10, 7, p. 2259-66 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glutamate receptor ligands: synthesis, stereochemistry, and enantiopharmacology of methylated 2-aminoadipic acid analogs

    Guldbrandt, M., Johansen, Tommy Nørskov, Frydenvang, Karla Andrea, Bräuner-Osborne, Hans, Stensbøl, T. B., Nielsen, Birgitte, Karla, R., Santi, F., Krogsgaard-Larsen, Povl & Madsen, Ulf, 2002, In : Chirality. 14, 4, p. 351-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors

    Jensen, Anders A., Mosbacher, J., Elg, S., Lingenhoehl, K., Lohmann, T., Johansen, Tommy Nørskov, Abrahamsen, B., Mattsson, J., Lehmann, A., Bettler, B. & Bräuner-Osborne, Hans, 2002, In : Molecular Pharmacology. 61, 6, p. 1377-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2003
  31. Published

    Stereostructure-activity studies on agonists at the AMPA and kainate subtypes of ionotropic glutamate receptors

    Johansen, Tommy Nørskov, Greenwood, J. R., Frydenvang, Karla Andrea, Madsen, Ulf & Krogsgaard-Larsen, Povl, 2003, In : Chirality. 15, 2, p. 167-79 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2004
  33. Published

    A stereochemical anomaly: the cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors

    Vogensen, S., Greenwood, J., Varming, A. R., Brehm, L., Pickering, Darryl S, Nielsen, Birgitte, Liljefors, T., Clausen, Rasmus Prætorius, Johansen, Tommy Nørskov & Krogsgaard-Larsen, Povl, 2004, In : Organic & Biomolecular Chemistry. 2, 2, p. 206-213

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2005
  35. Published

    GABA and Glutamate Receptor Ligands and Therapeutic Potential in CNS Disorders

    Madsen, Ulf, Greenwood, J., Johansen, Tommy Nørskov, Krogsgaard-Larsen, Povl, Liljefors, T., Nielsen, M. & Frølund, Bente, 2005, Drug Discovery Handbook. Wiley, p. 797–907

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  36. Published

    Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues

    Vogensen, S., Clausen, Rasmus Prætorius, Greenwood, J., Johansen, Tommy Nørskov, Pickering, Darryl S, Nielsen, Birgitte, Ebert, B. & Krogsgaard-Larsen, Povl, 5 May 2005, In : Journal of Medicinal Chemistry. 48, 9, p. 3438-3442

    Research output: Contribution to journalJournal articleResearchpeer-review

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