An antagonist of lipid A action in mammals has complex effects on lipid A induction of defence responses in the model plant Arabidopsis thaliana
Research output: Contribution to journal › Journal article › Research › peer-review
Gitte Erbs, Tina Tandrup Jensen, Alba Silipo, William Grant, J. Maxwell Dow, Antonio Molinaro, Michelangelo Parrilli, Mari-Anne Newman
Lipopolysaccharides, the ubiquitous part of the outer membrane of Gram-negative bacteria, and their derivatives are recognised by plants to trigger or potentiate particular defence responses such as induction of genes encoding pathogenesis-related proteins. The molecular mechanisms of LPS perception that underpin these effects in plants are, however, unknown. Here, lipid A from Halomonas magadiensis, which is an antagonist of lipid A action in human cells, was used to investigate lipid A action in plants. Our findings offer an insight into the different structural requirements for direct induction and potentiation of plant defences by lipid A.
|Journal||Microbes and Infection|
|Number of pages||4|
|Publication status||Published - 2008|
- LIFE - PAMPs, Halomonas magadiensis, Lipid A, Antagonist, Arabidopsis thaliana