An antagonist of lipid A action in mammals has complex effects on lipid A induction of defence responses in the model plant Arabidopsis thaliana

Research output: Contribution to journalJournal articleResearchpeer-review

Gitte Erbs, Tina Tandrup Jensen, Alba Silipo, William Grant, J. Maxwell Dow, Antonio Molinaro, Michelangelo Parrilli, Mari-Anne Newman

Lipopolysaccharides, the ubiquitous part of the outer membrane of Gram-negative bacteria, and their derivatives are recognised by plants to trigger or potentiate particular defence responses such as induction of genes encoding pathogenesis-related proteins. The molecular mechanisms of LPS perception that underpin these effects in plants are, however, unknown. Here, lipid A from Halomonas magadiensis, which is an antagonist of lipid A action in human cells, was used to investigate lipid A action in plants. Our findings offer an insight into the different structural requirements for direct induction and potentiation of plant defences by lipid A.
Original languageEnglish
JournalMicrobes and Infection
Volume10
Issue number5
Pages (from-to)571-574
Number of pages4
ISSN1286-4579
DOIs
Publication statusPublished - 2008

    Research areas

  • LIFE - PAMPs, Halomonas magadiensis, Lipid A, Antagonist, Arabidopsis thaliana

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