Research areas

  1. Published

    Phorbol Rearrangements. / Zimmermann, Tomas; Franzyk, Henrik; Christensen, Søren Brøgger.

    In: Journal of Natural Products, Vol. 81, No. 9, 15.09.2018, p. 2134-2137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Preparation of Enzyme-Activated Thapsigargin Prodrugs by Solid-Phase Synthesis. / Zimmermann, Tomas; Christensen, Søren Brøgger; Franzyk, Henrik.

    In: Molecules, Vol. 23, No. 6, 1463, 15.06.2018.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Urban Displacement and Resettlement in Zimbabwe: The Paradoxes of Propertied Citizenship. / Hammar, Amanda.

    In: African Studies Review, 12.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure/activity Relationship of Thapsigargin Inhibition on the Purified Golgi/secretory Pathway Ca2+/Mn2+-Transport ATPase (SPCA1a). / Jialin, Chen; de Raeymaecker, Joren ; Hovgaard, Jannik Brøndsted; Smaardijk, Susanne; Vandecaetsbeek, Ilse; Wuytack, Frank; Møller, Jesper Vuust; Eggermont, Jan; de Meyer, Marc; Christensen, Søren Brøgger; Vangheluwe, Peter.

    In: Journal of Biological Chemistry, Vol. 292, No. 17, 2017, p. 6938-6951.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. / Krall, Jacob; Jensen, Claus Hatt; Bavo, Francesco; Falk-Petersen, Christina Birkedahl; Haugaard, Anne Stæhr; Vogensen, Stine Byskov; Tian, Yongsong; Nittegaard-Nielsen, Mia; Sigurdardóttir, Sara Björk; Kehler, Jan; Kongstad, Kenneth Thermann; Gloriam, David E.; Clausen, Rasmus Prætorius; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 21, 2017, p. 9022-9039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Lithostratigraphy, geology and geochemisttry of the volcanic rocks of the Vaigat Formation on Disko and Nuussuaq, Paleocene of West Greenland. / Pedersen, Asger Ken; Larsen, Lotte Melchior; Pedersen, Gunver Krarup .

    Copenhagen : The Geological Survey of Denmark and Greenland, 2017. 244 p.

    Research output: Book/ReportBookResearchpeer-review

  7. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation. / Jensen, Christina Mernøe; Chow, Hsiao-Qing; Chen, Ming; Zhai, Lin; Frydenvang, Karla Andrea; Liu, Huizhen ; Franzyk, Henrik; Christensen, Søren Brøgger.

    In: European Journal of Medicinal Chemistry, Vol. 114, 2016, p. 118-133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Basic characteristics and kinetics of degradation in aqueous buffer of selected diclofenac prodrugs intended for joint injection. / Mertz, Nina; Larsen, Susan Weng; Larsen, Claus Selch.

    2016. Poster session presented at 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Glasgow, United Kingdom.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    Cytochrome P450 Mediated Drug Metabolism. / Olsen, Lars; Jørgensen, Flemming Steen; Oostenbrink, Chris.

    New Horizons in Predictive Drug Metabolism and Pharmacokinetics. ed. / Alan G.E. Wilson. Cambridge : Royal Society of Chemistry, 2016. p. 66-78.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  10. Published

    The potential of protein-nanomaterial interaction for advanced drug delivery. / Peng, Qiang; Mu, Huiling.

    In: Journal of Controlled Release, Vol. 225, 23.01.2016, p. 121-132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats. / Berthelsen, Ragna; Holm, Rene; Jacobsen, Jette; Kristensen, Jakob; Abrahamsson, Bertil; Müllertz, Anette.

    In: Molecular Pharmaceutics, Vol. 12, No. 4, 06.04.2015, p. 1062-1071.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Thapsigargin, origin, chemistry, structure-activity relationships and prodrug development. / Doan, Thi Quynh Nhu; Christensen, Søren Brøgger.

    In: Current Pharmaceutical Design, Vol. 21, No. 38, 10.2015, p. 5505-5517.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score. / Laustsen, Andreas Hougaard; Lohse, Brian.

    In: Toxicon, Vol. 104, 15.09.2015, p. 43-45.

    Research output: Contribution to journalLetterResearchpeer-review

  14. Published

    Noter til Organisk Kemi for Biovidenskab : Organisk og bioorganisk kemi 2015. / Nielsen, John.

    25 p. 2015, .

    Research output: Other contributionEducation

  15. Published

    The PPARalpha agonist, fenofibrate decreases levels of anorectic N-acylethanolamines in the small intestine of mice. / Diep, Thi Ai; Golbas, Golfam; Hansen, Harald S.

    2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  16. Published

    Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking. / Hauser, Alexander Sebastian.

    In: Medicinal Chemistry Research, Vol. 23, No. 8, 01.08.2014, p. 3861.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Brandt, Asbjørn; Halling-Sørensen, Bent; Björklund, Erland.

    In: International Journal of Environmental Analytical Chemistry, Vol. 93, No. 14, 25.02.2013, p. 1500-1512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Altered anziety/depression-like behaviours in mice deficient in tetrahydrobiopterin. / Nasser, Arafat; Birk Møller, Lisbeth; Andreasen T., Jesper.

    2013.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  19. Published

    Organ culture of C57BL/6 mouse arteries with LPS as an in vitro model of vascular inflammation. / Outzen, Emilie Middelbo; Mehryar, Rahila; Boonen, Harrie C.M.; Nielsen, Anette Sams; Sheykhzade, Majid.

    2013. Poster session presented at DRA Summer School 2013, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  20. Published

    Lactate dehydrogenase assay for assessment of polycation cytotoxicity. / Parhamifar, Ladan; Andersen, Helene; Moghimi, Seyed Moien.

    Nanotechnology for Nucleic Acid Delivery. Vol. 948 2013. p. 13-22.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 30, No. 1, 01.2013, p. 280-289.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Exploring the solid-form landscape of pharmaceutical hydrates : transformation pathways of the sodium naproxen anhydrate-hydrate system. / Raijada, Dharaben Kaushikkumar; Bond, Andrew; Larsen, Flemming Hofmann; Cornett, Claus; Qu, Haiyan; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 30, No. 1, 2013, p. 280-289.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Pollution Pathways of Pharmaceutical Residues in the Aquatic Environment on the Island of Mallorca, Spain. / Rodríguez-Navas, Carlos ; Björklund, Erland; Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Maya, Fernando; Forteza, Rafael; Cerdà, Víctor.

    In: Archives of Environmental Contamination and Toxicology, Vol. 61, No. 1, 2013, p. 56-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Liposomal temocene (m-THPPo) photodynamic treatment induces cell death by mitochondria-independent apoptosis. / Soriano, Jorge; Garcia-Diaz, Maria; Mora, Margarita; Sagristá, Maria Lluïsa; Nonell, Santi; Villanueva, Angeles; Stockert, Juan Carlos; Cañete, Magdalena.

    In: BBA General Subjects, Vol. 1830, No. 10, 28.05.2013, p. 4611-4620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pattern-oriented Agent-based Monte Carlo simulation of Cellular Redox Environment. / Tang, Jiaowei; Holcombe, Mike ; Boonen, Harrie C.M.

    2013. Poster session presented at DRA Summer School 2013, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterResearch

  26. Published

    Prolonged naproxen joint residence time after intra-articular injection of lipophilic solutions comprising a naproxen glycolamide ester prodrug in the rat. / Thing, Mette; Lu, Yi; Agårdh, Li; Larsen, Claus Selch; Ostergaard, Jesper; He, Wei; Wu, Wei; Larsen, Frank; Larsen, Susan Weng.

    In: International Journal of Pharmaceutics, Vol. 451, No. 1-2, 15.07.2013, p. 34-40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT). / Aksu, Buket; De Beer, Thomas; Folestad, Staffan; Ketolainen, Jarkko; Lindén, Hans; Lopes, Joao Almeida; de Matas, Marcel; Oostra, Wim; Rantanen, Jukka; Weimer, Marco.

    In: European Journal of Pharmaceutical Sciences, Vol. 47, No. 2, 29.09.2012, p. 402-405.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Håb om at ramme latente bakterier i deres skjul. / Bahnsen, Jesper Søborg; Water, Jorrit Jeroen; Foged, Camilla; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning 2012, Vol. 2012, 2012, p. 12-14.

    Research output: Contribution to journalJournal articleResearch

  29. Published

    Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane exctraction. / Balchen, Marte; Lund, Hanne ; Reubsaet, Léon; Pedersen-Bjergaard, Stig.

    In: Analytica Chimica Acta, Vol. 716, 2012, p. 16-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    In vitro efficacy testing of praziquantel, ivermectin, and oxfendazole against Taenia Solium cysts. / Cederberg, S.; Sikasunge, C.S.; Andersson, Åsa; Johansen, Maria Vang.

    In: Journal of Parasitology Research, Vol. 2012, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Role of excipients on solid-state properties of piroxicam during processing. / Christensen, Niels Peter Aae; Cornett, Claus; Rantanen, Jukka.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 1202-1211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Drugs for the neglected disease malaria based on natural products. / Christensen, Søren Brøgger; Bygbjerg, Ib Christian.

    Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. ed. / Corrado Tringali. 2. ed. Boca Raton : CRC Press, 2012. p. 525-550.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  33. Published

    Concise synthesis of new bridged-nicotine analogues. / Crestey, François; Hooyberghs, Geert ; Kristensen, Jesper Langgaard.

    In: Tetrahedron, Vol. 68, No. 5, 04.02.2012, p. 1417-1421.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    In vitro digestion testing of lipid-based delivery systems : calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. / Devraj, Ravi; Williams, Hywel D; Warren, Dallas B; Mullertz, Anette; Porter, Christopher J H; Pouton, Colin W.

    In: International Journal of Pharmaceutics, Vol. 441, No. 1-2, 2012, p. 323-333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies. / Escudier, B; Osanto, S; Ljungberg, B; Porta, C; Wagstaff, John; Mulders, Peter; Gore, Martin; Bex, A; Bellmunt, Jaquim; Bracarda, Sergio; Franklin, Alex; Honoré, Per Gustaf Hartvig; Ravaud, Alain; Stein, Jeanne van; Aziz, Zeb ; Akaza, Hideyuki .

    In: Cancer Treatment Reviews, Vol. 38, No. 2, 2012, p. 127-132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    License to kill : formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. / Foged, Camilla; Hansen, Jon; Agger, Else Marie.

    In: European Journal of Pharmaceutical Sciences, Vol. 45, No. 4, 2012, p. 482-491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection. / Gammelgaard, Bente; Rasmussen, Laura Hyrup; Gabel-Jensen, Charlotte; Steffansen, Bente.

    In: Biological Trace Element Research, Vol. 145, No. 2, 2012, p. 248-256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS. / Gammelgaard, Bente; Stürup, Stefan; Christensen, Malene Vinther.

    In: Metallomics, Vol. 4, No. 2, 2012, p. 149-155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca. / González, Carlos Rodriguez-Navas; Björklund, Erland; Forteza, Rafael; Cerdà, Victor.

    In: International Journal of Environmental Analytical Chemistry, Vol. 92, No. 12, 2012, p. 1-16, iFirst.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Introduction to pharmaceutical chemical analysis. / Hansen, Steen Honore'; Pedersen-Bjergaard, Stig; Rasmussen, Knut Einar.

    Chichester : Wiley, 2012. 477 p.

    Research output: Book/ReportBookEducationpeer-review

  41. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains. / Haq, S Raza; Chi, Celestine N; Bach, Anders; Dogan, Jakob; Engström, Åke; Hultqvist, Greta; Karlsson, O. Andreas; Lundström, Patrik; Montemiglio, Linda Celeste; Strømgaard, Kristian; Gianni, Stefano; Jemth, Per.

    In: Journal of the American Chemical Society, Vol. 134, No. 1, 01.2012, p. 599-605.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    An electrochemical approach to protein adsorption at charged interfaces. / Hartvig, Rune Andersen.

    København : Det Farmaceutiske Fakultet, 2012. 127 p.

    Research output: Book/ReportPh.D. thesisResearch

  43. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.

    In: Langmuir, Vol. 28, No. 3, 2012, p. 1804-1815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Forced degradation of therapeutic proteins. / Hawe, Andrea; Wiggenhorn, Michael; van de Weert, Marco; Garbe, Joerg H. O.; Mahler, Hanns-Christian; Jiskoot, Wim.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 895-913.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Evaluation of the antibacterial activity of Chilean plants traditionally used for wound healing therapy against multidrug-resistant Staphylococcus aureus. / Holler, Jes Gitz; Søndergaard, Karen ; Slotved, Hans-Christian; Gúzman, Alfonso; Mølgaard, Per.

    In: Planta Medica, Vol. 78, No. 2, 01.2012, p. 200-205.

    Research output: Contribution to journalLetterResearchpeer-review

  46. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful. / Holm, Rene; Hesselkilde, Janne Z.; Jørgensen, Erling B.; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 47, 2012, p. 347-351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Interaction of peptidomimetics with bilayer membranes : biophysical characterization and cellular uptake. / Jing, Xiaona; Kasimova, Marina Robertovna; Simonsen, Anders H.; Jørgensen, Lene; Malmsten, Martin; Franzyk, Henrik; Foged, Camilla.

    In: Langmuir, Vol. 28, No. 11, 2012, p. 5167-5175.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Quality assessment of Tulbaghia rhizomes. / Jäger, Anna; Stafford, Gary Ivan.

    In: South African Journal of Botany, Vol. 82, 09.2012, p. 92-98.

    Research output: Contribution to journalJournal articleResearchpeer-review

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