Research areas

  1. Published

    Tool boxes for an integrated ecological and environmental management. / Jørgensen, Sven Erik; Nielsen, Søren Nors.

    In: Ecological Indicators, Vol. 21, 2012, p. 104-109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators. / Kaae, Birgitte H; Harpsøe, Kasper; Kvist, Trine; Mathiesen, Jesper M; Mølck, Christina; Gloriam, David E; Jimenez, Hermogenes N; Uberti, Michelle A; Nielsen, Søren M; Nielsen, Birgitte; Bräuner-Osborne, Hans; Sauerberg, Per; Clausen, Rasmus Prætorius; Madsen, Ulf.

    In: ChemMedChem, Vol. 7, No. 3, 2012, p. 440-451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service. / Kaae, Susanne; Nørgaard, Lotte Stig.

    In: International Journal of Pharmacy Practice, Vol. 20, 2012, p. 99-106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor. / Knudsen, Nina Østergaard; Schiffelers, Raymond M.; Jørgensen, Lene; Hansen, Jens; Frøkjær, Sven; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 428, No. 1-2, 2012, p. 171-177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction. / Koradia, Vishal Shamji; Tenho, Mikko; Diego, Heidi Lopez de; Ringkjøbing-Elma, Michiel ; Sonnergaard, Jørn; Salonen, Jamo; Lehto, Vesa-Pekka; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 29, No. 1, 2012, p. 134-144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. / Krintel, Christian; Frydenvang, Karla; Olsen, Lars; Kristensen, Maria T; de Barrios, Oriol; Naur, Peter; Francotte, Pierre; Pirotte, Bernard; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 173-178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil. / Kristensen, Janni Brogaard; Jørgensen, Henry; Mu, Huiling.

    In: European Journal of Lipid Science and Technology, Vol. 114, No. 2, 2012, p. 146-152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors. / Kristensen, Line Hyltoft.

    København : Faculty of Health and Medical Sciences, University of Copenhagen, 2012. 168 p.

    Research output: Book/ReportPh.D. thesis

  9. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. / Kristensen, Line Hyltoft; Nielsen, Anders Laerke; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Kastrup, Jette Sandholm; Helin, Kristian; Olsen, Lars; Gajhede, Michael.

    In: F E B S Journal, Vol. 279, No. 11, 06.2012, p. 1905-1914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Design space approach in the optimization of the spray-drying process. / Lebrun, Pierre; Krier, Fabrice; Mantanus, Jérôme ; Grohganz, Holger; Yang, Mingshi; Rozet, Eric; Boulanger, Bruno; Evrard, Brigitte; Rantanen, Jukka; Hubert, Philippe.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 80, No. 1, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.

    In: Journal of Surfactants and Detergents, Vol. 15, 2012, p. 9-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression. / Lunøe, Kristoffer; Martinez-Sierra, Justo Giner ; Gammelgaard, Bente; Alonso, J. Ignacio Garcia.

    In: Analytical and Bioanalytical Chemistry, Vol. 402, No. 9, 2012, p. 2749-2763.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy). / Marchi, Michela; Jørgensen, Sven Erik; Pulselli, Federico Maria; Marchettini, Nadia; Bastianoni, Simone.

    In: Ecological Modelling, Vol. 225, 2012, p. 40-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo. / Müllertz, Anette; Fatouros, Dimitrios G.; Smith, James R.; Vertzoni, Maria; Reppas, Christos.

    In: Molecular Pharmaceutics, Vol. 9, No. 2, 2012, p. 237-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS). / Nguyen, Trinh Thi Nhu Tam; Østergaard, Jesper; Stürup, Stefan; Gammelgaard, Bente.

    In: Analytical and Bioanalytical Chemistry, Vol. 402, 2012, p. 2131-2139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    3-Alkyl- and 3-amido-isothiazoloquinolin-4-ones as ligands for the benzodiazepine site of GABAA receptors. / Nilsson, Jakob; Nielsen, Elsebet Østergaard; Liljefors, Tommy; Nielsen, Mogens Peter Cherly; Sterner, Olov.

    In: Bioorganic Chemistry, Vol. 40, 02.2012, p. 125-130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction. / Pan, Yue; Gerasimov, Madina R; Kvist, Trine; Wellendorph, Petrine; Madsen, Karsten Kirkegaard; Pera, Elena; Lee, Hyunbeom; Schousboe, Arne; Chebib, Mary; Bräuner-Osborne, Hans; Craft, Cheryl M; Brodie, Jonathan D; Schiffer, Wynne K; Dewey, Stephen L; Miller, Stephen R; Silverman, Richard B.

    In: Journal of Medicinal Chemistry, Vol. 55, No. 1, 01.01.2012, p. 357-366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Role of Cu2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides. / Pedersen, Jeppe Trudslev.

    København : Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet, 2012. 85 p.

    Research output: Book/ReportPh.D. thesis

  19. Published

    Behaviour of HPMC compacts investigated using UV-imaging. / Pekka Pajander, Jari; Baldursdottir, Stefania G.; Rantanen, Jukka; Østergaard, Jesper.

    In: International Journal of Pharmaceutics, Vol. 427, No. 2, 2012, p. 345-353.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A robust force field based method for calculating conformational energies of charged drug-like molecules. / Pøhlsgaard, Jacob; Harpsøe, Kasper; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 2, 2012, p. 409-419.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation. / Rand, Kasper Dyrberg; Pringle, Steven D.; Morris, Michael; Brown, Jeffery M.

    In: Analytical Chemistry, Vol. 84, No. 4, 2012, p. 1931-1940.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors : Unique role of halogen bonding revealed. / Rohde, Line Aagot Hede; Ahring, Philip Kiær; Jensen, Marianne Lerbech; Nielsen, Elsebet Østergaard; Peters, Dan; Helgstrand, Charlotte; Krintel, Christian; Harpsøe, Kasper; Gajhede, Michael; Kastrup, Jette Sandholm; Balle, Thomas.

    In: The Journal of Biological Chemistry, Vol. 287, No. 6, 03.02.2012, p. 4248-4259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Comment on "Binding free energies of inhibitors to iron porphyrin complex as a model for cytochrome P450". / Rydberg, Patrik.

    In: Biopolymers, Vol. 97, No. 4, 04.2012, p. 250-251.

    Research output: Contribution to journalComment/debateResearchpeer-review

  24. Published

    Ligand-based site of metabolism prediction for cytochrome P450 2D6. / Rydberg, Patrik; Olsen, Lars.

    In: A C S Medicinal Chemistry Letters, Vol. 3, No. 1, 12.01.2012, p. 69-73.

    Research output: Contribution to journalLetterResearchpeer-review

  25. Published

    Cyclodextrins : efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. / Stojanov, Mladen; Nielsen, Hanne Mørck; Larsen, Kim Lambertsen.

    In: International Journal of Pharmaceutics, Vol. 422, No. 1-2, 2012, p. 349-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Genetic fuzzy system modeling and simulation of vascular behaviour. / Tang, Jiaowei; Boonen, Harrie C.M.

    2012. Poster session presented at Danish Cardiovascular Research Academy 2012 summer meeting at the Sandbjerg Estate , Sønderborg, Denmark.

    Research output: Contribution to conferencePosterResearchpeer-review

  27. Published

    In vitro release from oil injectabels for intra-articular administration : importance of interfacial area, diffusivity and partitioning. / Thing, Mette Agergaard; Larsen, Claus Selch; Østergaard, Jesper; Jensen, Henrik; Larsen, Susan Weng.

    In: European Journal of Pharmaceutical Sciences, Vol. 45, No. 3, 2012, p. 351-357.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems. / Thomas, Nicky; Müllertz, Anette; Graf, Anja; Rades, Thomas.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 5, 2012, p. 1721-1731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Biased agonism of the calcium-sensing receptor. / Thomsen, Alex Rojas Bie; Hvidtfeldt, Maja; Bräuner-Osborne, Hans.

    In: Cell Calcium, Vol. 51, No. 2, 02.2012, p. 107-116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine. / Thunig, Janina; Flø, Linda; Pedersen-Bjergaard, Stig; Hansen, Steen Honore'; Janfelt, Christian.

    In: Rapid Communications in Massspectrometry, Vol. 26, No. 2, 2012, p. 133-140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    A 3D-QSAR-driven approach to binding mode and affinity prediction. / Tosco, Paolo; Balle, Thomas.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 2, 2012, p. 302-307.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Chemical composition of the essential oil from Microlicia graveolens growing wild in Minas Gerais. / Toudahl, Anja B; Filho, Sidney A V; Souza, Gustavo H B; Morais, Luisa D; dos Santos, Orlando D H ; Jäger, Anna.

    In: Revista Brasileira de Farmacognosia, Vol. 22, No. 3, 05.2012, p. 680-681.

    Research output: Contribution to journalLetterResearchpeer-review

  33. Published

    Assessing element-specific patterns of bioaccumulation across New England lakes. / Ward, Darren M.; Mayes, Brandon; Stürup, Stefan; Folt, Carol L.; Chen, Celia Y.

    In: Science of the Total Environment, Vol. 421-422, No. 3-4, 2012, p. 230-237.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Polymer-mediated anti-solvent crystallization of nitrendipine: Monodispersed spherical crystals and growth mechanism. / Xia, Dengning; Ouyang, Mei; Wu, Jian-Xiong; Jiang, Yanbo; Piao, Hongyu; Sun, Shaoping; Zheng, Li; Rantanen, Jukka; Cui, Fude; Yang, Mingshi.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 158-169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers. / Xia, Dengning; Wu, Jian-Xiong; Cui, Fude; Qu, Haiyan; Rades, Thomas; Rantanen, Jukka; Yang, Mingshi.

    In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 5, 15.08.2012, p. 446-454.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions : the effect of lipid composition. / Yaghmur, Anan; Rappolt, Michael; Østergaard, Jesper; Larsen, Claus Selch; Larsen, Susan Weng.

    In: Langmuir, Vol. 28, No. 5, 2012, p. 2881-2889.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Self-assembled nanostructures of fully hydrated monoelaidin - Elaidic and monoelaidin - Oleic acid systems. / Yaghmur, Anan; Satori, Barbara; Rappolt, Michael.

    In: Langmuir, Vol. 28, 2012, p. 10105-10119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells. / Yang, Lin; Fawcett, J. Paul; Østergaard, Jesper; Zhang, Hu; Tucker, Ian G.

    In: Molecular Pharmaceutics, Vol. 9, No. 1, 2012, p. 29-36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis. / Ye, Fengbin; Jensen, Henrik; Larsen, Susan Weng; Yaghmur, Anan; Larsen, Claus Selch; Østergaard, Jesper.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 61, 2012, p. 176-183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix. / Ye, Fengbin; Larsen, Susan Weng; Yaghmur, Anan; Jensen, Henrik; Larsen, Claus Selch; Østergaard, Jesper.

    In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 1-2, 2012, p. 72-78.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    NMR spectroscopy for metabolic profiling of plant extracts. / Yilmaz, Ali.

    København : Faculty of Health and Medical Sciences, University of Copenhagen, 2012. 114 p.

    Research output: Book/ReportPh.D. thesis

  43. Published

    RS-Predictor models augmented with SMARTCyp reactivities : robust metabolic regioselectivity predictions for nine CYP isozymes. / Zaretzki, Jed; Rydberg, Patrik; Bergeron, Charles; Bennett, Kristin P; Olsen, Lars; Breneman, Curt Mark.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 6, 2012, p. 1637-1659.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Adverse drug reactions following immunization in Danish children : retrospective analysis of spontaneous reports submitted to the Danish Medicines Agency. / Aagaard, Lise; Hansen, Erik Wind; Hansen, Ebba Holme.

    Science against microbial pathogens: communicating current research and technical advances. ed. / A. Méndez-Vilas. Vol. 1 Badajoz : Formatex, 2011. p. 407-413 (Microbiology series; No. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  45. Published

    Adverse events following immunization in children : retrospective analysis of spontaneous reports over a decade. / Aagaard, Lise; Hansen, Erik Wind; Hansen, Ebba Holme.

    In: European Journal of Clinical Pharmacology, Vol. 67, No. 1, 2011, p. 283-288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Characteristics of adverse drug reactions related to off-label prescribing in the Danish paediatric population. / Aagaard, Lise; Hansen, Ebba Holme.

    2011. Abstract from 3rd PharmSciFair, Prague, Czech Republic.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  47. Published
  48. Published

    Biological targeting and innovative therapeutic interventions with phage-displayed peptides and structured nucleic acids (aptamers). / Ahmadvand, Davoud; Rahbarizadeh, Fatemeh; Moghimi, Seyed Moien.

    In: Current Opinion in Biotechnology, Vol. 22, No. 2, 2011, p. 832-838.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew D; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 19.07.2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

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