Research areas

  1. Published

    Development of solid-phase aziridine chemistries: Piperazine scaffolds and unnatural amino acid building blocks

    Ottesen, L. K., 2010, København: Det Farmaceutiske Fakultet. 139 p.

    Research output: Book/ReportPh.D. thesisResearch

  2. Published

    Ring opening of a resin-bound chiral aziridine with phenol nucleophiles

    Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2010, In : Journal of Organic Chemistry. 75, 15, p. 4983-4991

    Research output: Contribution to journalJournal article

  3. Published

    Gold-embedded photosensitive liposomes for drug delivery: Triggering mechanism and intracellular release

    Paasonen, L., Sipilä, T., Subrizi, A., Laurinmäki, P., Butcher, S. J., Rappolt, M., Yaghmur, Anan, Urtti, A. & Yliperttula, M., 2010, In : Journal of Controlled Release. 147, p. 136-143

    Research output: Contribution to journalJournal article

  4. Published

    Polycation cytotoxicity: a delicate matter for nucleic acid therapy - focus on polyethylenimine

    Parhamifar, L., Larsen, A. K., Hunter, A. C., Andresen, T. L. & Moghimi, S. M., 2010, In : Soft Matter. 6, p. 4001-4009

    Research output: Contribution to journalJournal article

  5. Published

    Radioiododestannyllation of novel GHB neuroreceptor ligands

    Pedersen, M. H. F., Høg, S., Wellendorph, Petrine & Martiny, L., 2010, In : Journal of Labelled Compounds and Radiopharmaceuticals. 5-6, p. 318-320

    Research output: Contribution to journalConference article

  6. Published

    Anticonvulsant effects of Searsia dentata (Anacardiaceae) leaf extract in rats

    Pedersen, M. E., Baldwin, R. A., Niquet, J., Stafford, G. I., van Staden, J., Wasterlain, C. G. & Jäger, A. K., 2010, In : Phytotherapy Research. 24, 6, p. 924-927

    Research output: Contribution to journalJournal article

  7. Published

    Liquid-phase microextraction (LPME) utilizing porous hollow fibers: fundamental extraction techniques

    Pedersen-Bjergaard, Stig, Rasmussen, K. E. & Jönsson, J. Å., 2010, Handbook of sample preparation. Pawliszyn, J. & Lord, H. L. (eds.). Hoboken: Wiley, p. 125-148

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  8. Published

    EASL clinical practice guidelines on the management of asites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis

    Pere, G., Angeli, P., Lenz, K., Søren, M., Moore, K., Moreau, R., Merkel, C., Larsen, H. R., Bernardi, M., Garcia-Tsao, G. & Hayes, P., 1 Sep 2010, In : Journal of Hepatology. 53, 3, p. 397-417 30 p.

    Research output: Contribution to journalJournal article

  9. Published

    The protease inhibitors ritonavir and saquinavir influence lipid metabolism: a pig model for the rapid evaluation of new drugs

    Petersen, E., Mu, Huiling, Porsgaard, T. & Bertelsen, L. S., 2010, In : Antiviral Therapy. 15, p. 243-251

    Research output: Contribution to journalJournal article

  10. Published

    On-chip electro membrane exctraction

    Petersen, Nickolaj J., Jensen, Henrik, Hansen, S. H., Foss, S. T., Snakenborg, D. & Pedersen-Bjergaard, Stig, 2010, In : Microfluidics and Nanofluidics. 9, p. 881-888

    Research output: Contribution to journalJournal article

  11. Published

    Influences of socio-economic factors for adverse drug reaction reporting patterns: a retrospective analysis of reports from 2000 to 2009 in Vigibase.

    Petersen, P. S., Melskens, L. & Aagaard, L., 2010, In : Drug Safety. 33, 10, p. 903

    Research output: Contribution to journalConference abstract in journal

  12. Published

    Ligand-based drug design

    Pettersson, I., Balle, T. & Liljefors, T., 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 43-57

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  13. Published

    Influence of glycosylation on the adsorption of Thermomyces lannuginosus lipase to hydrophobic and hydrophilic surfaces

    Pinholt, C., Fanø, M., Wiberg, C., Hostrup, S., Bukrinsky, J. T., Frøkjær, Sven, Norde, W. & Jørgensen, Lene, 2010, In : European Journal of Pharmaceutical Sciences. 40, 4, p. 273-281

    Research output: Contribution to journalJournal article

  14. Published

    Computational prediction of binding affinity for CYP1A2-ligand complexes using empirical free energy calculations

    Poongavanam, V., Olsen, L., Jørgensen, Flemming Steen, Vermeulen, N. P. E. & Oostenbrink, C., 2010, In : Drug Metabolism and Disposition. 38, 8, p. 1347-1354

    Research output: Contribution to journalJournal article

  15. Published

    Cytochrome P450 in action: Rationalization and prediction through In Silico modeling of CYP1A2

    Poongavanam, V., 2010, København: Det Farmaceutiske Fakultet. 176 p.

    Research output: Book/ReportPh.D. thesisResearch

  16. Published

    Multiresidue method for the determination af 32 human and veterinary pharmaceuticals in soil and sediment by pressurized-liquid extraction and LC-MS/MS

    Pérezz-Carrera, E., Hansen, M., León, V. M., Björklund, B. E., Krogh, K. A., Halling-Sørensen, B. & González-Mazo, E., 2010, In : Analytical and Bioanalytical Chemistry. 398, p. 1173-1184

    Research output: Contribution to journalJournal article

  17. Published

    A novel hybrid chromatography - crystallization process for the isolation and purification of a natural pharmaceutical ingredient from a medicinal herb

    Qu, H., Christensen, K. B., Fretté, X. C., Tian, F., Qu, H., Rantanen, Jukka & Christensen, L. P., 2010, In : Organic Process Research and Development. 14, 3, p. 585-591

    Research output: Contribution to journalJournal article

  18. Published

    Chromatography-crystallization hybrid process for artemisinin purification from artemisia annua

    Qu, H., Christensen, K. B., Fretté, X., Tian, F., Rantanen, Jukka & Christensen, L. P., 2010, In : Chemical Engineering and Technology. 33, 5, p. 791-796

    Research output: Contribution to journalJournal article

  19. Published

    The molecular chaperone a-crystalin as an excipient for protein formulations

    Rasmussen, T., 2010, Det Farmaceutiske Fakultet. 74 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    The molecular chaperone a-crystallin as an excipient in an insulin formulation

    Rasmussen, T., Tantipolphan, R., van de Weert, Marco & Jiskoot, W., 2010, In : Pharmaceutical Research. 27, p. 1337-1347

    Research output: Contribution to journalJournal article

  21. Published

    Redissolution and polymorphic characterization of a poorly water-soluble drug precipitated during in vitro lipolysis from a lipid-based formulation

    Ren, S., Ogbonna, A., Koradia, V. S., Sassene, P. J., Rades, T. & Mullertz, Anette , Nov 2010.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Patient decision making: responses to illness and treatment

    Rickles, N. M., Britten, N., Traulsen, Janine Marie & Bissell, P., 2010, Social and behavioral aspects of pharmaceutical care. Rickles, N. M., Wertheimer, A. I. & Smith, M. C. (eds.). 2nd. ed. ed. Boston, USA: Jones and Bartlett Publishers, p. 177-194

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  23. Published

    Partial agonists and subunit selectivity at NMDA receptors

    Risgaard, R., Hansen, K. B. & Clausen, Rasmus Prætorius, 17 Dec 2010, In : Chemistry: A European Journal. 16, 47, p. 13910-13918

    Research output: Contribution to journalReview

  24. Published

    Branched nanotrees with immobilized acetylcholine esterase for nanobiosensor applications

    Risveden, K., Dick, K. A., Bhand, S., Rydberg, P. Å. A., Samuelson, L. & Danielsson, B., 2010, In : Nanotechnology. 21, 5, p. 055102 8 p.

    Research output: Contribution to journalJournal article

  25. Published

    Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder

    Rode, F., Svalø, J., Sheykhzade, Majid & Rønn, L. C. B., 2010, In : European Journal of Pharmacology. 638, 1-3, p. 121-127 6 p.

    Research output: Contribution to journalJournal article

  26. Published

    A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa

    Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, Søren Brøgger, Søhoel, H. & Massanet, G. M., 2010, In : Planta Medica. 76, 3, p. 284-290

    Research output: Contribution to journalJournal article

  27. Published

    Determination of pharmaceuticals in environmental and biological matrices using pressurised liquid extraction - Are we developing sound extraction  methods ?

    Runnqvist, H. E. S., Bak, S. A., Hansen, M., Styrishave, Bjarne, Halling-Sørensen, B. & Björklund, B. E., 2010, In : Journal of Chromatography A. 1217, 16, p. 2447-2470

    Research output: Contribution to journalJournal article

  28. Published

    SMARTCyp web service

    Rydberg, P., Gloriam, David E. & Olsen, L., 2010

    Research output: Non-textual formInteractive productionResearch

  29. Published

    The SMARTCyp cytochrome P450 metabolism prediction server

    Rydberg, P., Gloriam, David E. & Olsen, L., 1 Dec 2010, In : Bioinformatics. 26, 23, p. 2988-2989

    Research output: Contribution to journalLetter

  30. Published

    SMARTCyp: A 2D method for prediction of cytochrome P450-mediated drug metabolism

    Rydberg, P., Gloriam, David E., Zaretzki, J., Breneman, C. & Olsen, L., 15 Mar 2010, In : ACS Medicinal Chemistry Letters. 1, 3, p. 96-100

    Research output: Contribution to journalLetter

  31. Published

    Effects of the veterinary pharmaceutical ivermectin on soil invertebrates in laboratory tests

    Römbke, J., Krogh, K. A., Moser, T., Scheffczyk, A. & Liebig, M., 2010, In : Archives of Environmental Contamination and Toxicology. 58, 2, p. 332-340

    Research output: Contribution to journalJournal article

  32. Published

    Phylogeny as selection tool for exploring CNS-activity in the Amaryllidaceae

    Rønsted, Nina, Bay-Smidt, M. G. K., Krydsfeldt, K., van Staden, J., Stafford, G. I. & Jäger, A. K., Aug 2010, In : Planta Medica. 76, 12, p. 1178

    Research output: Contribution to journalConference article

  33. Published

    Planternes slægtskab som skattekort til nye lægemidler

    Rønsted, Nina, Brodin, Birger, Christensen, Søren Brøgger, Eriksson, A. H. & Jäger, A. K., Dec 2010, In : Lægemiddelforskning. 2010, p. 19-21

    Research output: Contribution to journalJournal article

  34. Published

    Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)

    Saaby, L., Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In : Planta Medica. 76, 12, p. 1171

    Research output: Contribution to journalConference abstract in journal

  35. Published
  36. Published

    Docking to flexible nicotinic acetylcholine receptors: a validation study using the acetylcholine binding protein

    Sander, T., Bruun, A. T. & Balle, T., 2010, In : Journal of Molecular Graphics and Modelling. 29, 3, p. 415-424

    Research output: Contribution to journalJournal article

  37. Published

    Precipitation of a poorly soluble model drug during in vitro lilpolysis: characterization and dissolution of the precipitate

    Sassene, P. J., Knopp, M. M., Hesselkilde, J. Z., Koradia, V. S., Larsen, A. T., Rades, T. & Mullertz, Anette , 2010, In : Journal of Pharmaceutical Sciences. 99, 12, p. 4982-4991

    Research output: Contribution to journalJournal article

  38. Published

    Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus

    Schou, J., Kristiansen, Uffe, Stafford, G. I., van Heerden, F. & Jäger, A., Aug 2010, In : Planta Medica. 76, 12, p. 1217

    Research output: Contribution to journalConference abstract in journal

  39. Published

    New discoveries in isotopic labelling of organic molecules & flow chemistry: a useful technique in organic synthesis

    Schou, S. C., 2010, København: Det Farmaceutiske Fakultet. 145 p.

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In : Journal of Neurochemistry. s1, p. 288-289

    Research output: Contribution to journalConference abstract in journal

  41. Published
  42. Published

    Glial cell biology: neuronal-glial interaction in nutrition and amino-acid-mediated neurotransmission

    Schousboe, Arne & Waagepetersen, Helle S., 2010, The newborn brain: Neuroscience and clinical applications. Lagercrantz, H., Hanson, M. A., Ment, L. R. & Peebles, D. M. (eds.). 2 ed. Cambridge: Cambridge University Press, p. 121-128

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  43. Published

    Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit

    Selen, A., Cruanes, M. T., Mullertz, Anette , Dicikinsion, P. A., Cook, J. A., Polli, J. E., Kesisoglou, F., Crison, J., Johnson, K. C., Muirhead, G. T., Schofield, T. & Tsong, Y., 2010, In : The AAPS Journal. 12, 3, p. 465-472

    Research output: Contribution to journalReview

  44. Published

    Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis

    Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2010, In : Journal of Cerebral Blood Flow and Metabolism. 30, 8, p. 1527-37 10 p.

    Research output: Contribution to journalJournal article

  45. Published

    Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications

    Sikanen, T., Pedersen-Bjergaard, Stig, Jensen, Henrik, Kostiainen, R., Rasmussen, K. E. & Kotiaho, T., 2010, In : Analytica Chimica Acta. 658, p. 133-140

    Research output: Contribution to journalJournal article

  46. Published

    Pitfalls in the sample preparation and analysis of N-acylethanolamines

    Skonberg, C., Artmann, A., Cornett, Claus, Hansen, S. H. & Hansen, Harald S., 2010, In : Journal of Lipid Research. 51, p. 3062-3073

    Research output: Contribution to journalJournal article

  47. Published

    Small biomolecular scaffolds for improved biosensor performance

    Skottrup, P. D., 2010, In : Analytical Biochemistry. 406, 1, p. 1-7 7 p.

    Research output: Contribution to journalJournal article

  48. Published

    Superparamagnetic bead interactions with functionalized surfaces characterized by an immunomicroarray

    Skottrup, P. D., Hansen, M. F., Moresco, J. L., Deryabina, M., Svendsen, W. E., Jakobsen, M. H. & Dufva, M., 2010, In : Acta Biomaterialia. 6, 10, p. 3936-3946 11 p.

    Research output: Contribution to journalJournal article

  49. Published

    Homology modelling of the GABA transporter and analysis of tiagabine binding

    Skovstrup, S., Taboureau, O., Bräuner-Osborne, Hans & Jørgensen, Flemming Steen, 2010, In : ChemMedChem. 5, 7, p. 986-1000

    Research output: Contribution to journalJournal article

  50. Published

    Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex

    Jensen, Dorte Skytt, Madsen, K. K., Pajecka, K., Schousboe, Arne & Waagepetersen, Helle S., 2010, In : Neurochemical Research. 35, 12, p. 2043-2052 10 p.

    Research output: Contribution to journalJournal article

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