Research areas

  1. Published

    On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds. / Larsen, Susan Weng; Frost, Anna Buus; Østergaard, Jesper; Marcher, Hermann; Larsen, Claus Selch.

    In: European Journal of Pharmaceutical Sciences, Vol. 34, No. 1, 2008, p. 37-44.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model. / Larsen, Susan Weng; Østergaard, Jesper; Poulsen, Sara; Schulz, Bjørn; Larsen, Claus Selch.

    In: European Journal of Pharmaceutical Sciences, Vol. 31, No. 3-4, 2007, p. 172-179.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Computeren er medicinalkemikerens arbejdshest. / Larsen, Simon Birksø; Olsen, Lars; Jørgensen, Flemming Steen.

    In: Lægemiddelforskning, 2009, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Computational studies of the human peptide transporter (hPEPT1) and development of tools for virtual screening. / Larsen, Simon Birksø.

    København : Det Farmaceutiske Fakultet, 2010. 111 p.

    Research output: Book/ReportPh.D. thesis

  5. Published

    Palladium-catalyzed monoamination of dihalogenated benzenes. / Larsen, Simon Birksø; Bang-Andersen, Benny; Johansen, Tommy Nørskov; Jørgensen, Morten.

    In: Tetrahedron, Vol. 64, No. 13, 2008, p. 2938-2950.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Discovery of ligands for the human intestinal di-/tripeptide transporter (hPEPT1) using af QSAR-assisted virtual screening strategy. / Larsen, Simon Birksø; Omkvist, Diana Højmark; Larsen, Birger Brodin; Nielsen, Carsten Uhd; Steffansen, Bente; Olsen, Lars; Jørgensen, Flemming Steen.

    In: ChemMedChem, Vol. 4, No. 9, 2009, p. 1439-1445.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Forbedret optagelse af lægemidler i organismen : computeren viser vejen. / Larsen, Simon Birksø; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Dansk Kemi, Vol. 91, No. 6/7, 2010, p. 18-20.

    Research output: Contribution to journalJournal articleResearch

  8. Published

    QSAR models for the human H+/peptide symporter, hPEPT1: Affinity prediction using alignment-independent descriptors. / Larsen, Simon Birksø; Jørgensen, Flemming Steen; Olsen, Lars.

    In: Journal of Chemical Information and Modeling, Vol. 48, No. 1, 2008, p. 233-241.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Intestinal gaboxadol absorption via PAT1 (SLC36A1) : modified absorption in vivo following co-administration of L-tryptophan. / Larsen, Mie; Larsen, R.; Jensen, K. G.; Larsen, Birger Brodin; Nielsen, Carsten Uhd.

    In: British Journal of Pharmacology, Vol. 157, 2009, p. 1380-1389.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1 : Characterization of conditions for affinity and transport experiments in Caco-2 cells. / Larsen, Mie; Larsen, Birger Brodin; Frølund, Bente; Nielsen, Carsten Uhd.

    In: European Journal of Pharmaceutical Sciences, Vol. 35, No. 1-2, 2008, p. 86-95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid. / Larsen, Jesper Tungelund; Stærk, Dan; Cornett, Claus; Hansen, Steen Honore'; Jaroszewski, Jerzy Witold.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 49, 2009, p. 839-842.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Impurities in drugs : Analysis of drug-excipient reactions. / Larsen, Jesper Tungelund.

    Det Farmaceutiske Fakultet, 2010. 99 p.

    Research output: Book/ReportPh.D. thesis

  13. Published

    Reaction between drug substances and pharmaceutical excipients : formation of citric acid esters and amides of carvedilol in the solid state. / Larsen, Jesper; Cornett, Claus; Jaroszewski, Jerzy Witold; Hansen, Steen H.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 49, No. 1, 2009, p. 11-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Role of in vitro release models in formulation development and quality control of parenteral depots. / Larsen, Claus Selch; Larsen, Susan Weng; Jensen, Henrik; Yaghmur, Anan; Østergaard, Jesper.

    In: Expert Opinion on Drug Delivery, Vol. 6, No. 12, 2009, p. 1283-1295.

    Research output: Contribution to journalReviewResearch

  15. Published

    Controlled release - macromolecular prodrugs. / Larsen, Claus Selch; Østergaard, Jesper; Larsen, Susan Weng.

    Prodrugs: challenges and rewards. ed. / Valentino J. Stella; Ronald T. Borchardt; Michael J. Hageman; Reza Oliyai; Hans Maag; Jefferson W. Tilley. New York : Springer, 2007. p. 379-416.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  16. Published

    Structure and function of absorption barriers. / Larsen, Birger Brodin; Steffansen, Bente; Nielsen, Carsten Uhd.

    Molecular biopharmaceutics: Aspects of drug characterisation, drug delivery and dosage form evaluation. ed. / Bente Steffansen; Birger Brodin; Carsten Uhd Nielsen. Pharmaceutical Press, 2010. p. 115-131 (ULLA Pharmacy Series).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  17. Published

    Selection of a lipase for development of an in vitro gastric lipid digestion model. / Larsen, Anne Tungelund; Jensen, Linda Grøn; Hansen, Karen Kleberg; Müllertz, Anette.

    2010. Poster session presented at 2010 AAPS Annual Meeting and Exposition, New Orleans, United States.

    Research output: Contribution to conferencePosterResearch

  18. Published

    In vitro lipolysis models as a tool for the characterization of oral lilpid and surfactant based drug delivery systems. / Larsen, Anne Tungelund; Sassene, Philip; Müllertz, Anette.

    In: International Journal of Pharmaceutics, Vol. 417, No. 1-2, 2011, p. 245-255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Lipid-based formulations for danazol containing a digestible surfactant, labrafil M2125CS : In vivo bioavailability and dynamic in vitro lipolysis. / Larsen, Anne; Holm, René; Pedersen, Mette Lund; Müllertz, Anette.

    In: Pharmaceutical Research, Vol. 25, No. 12, 2008, p. 2769-2777.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The impact of an automated dose-dispensing scheme on user compliance, medication understanding, and medication stockpiles. / Larsen, Anna Bira; Haugbølle, Lotte Stig.

    In: Research in Social and Administrative Pharmacy, Vol. 3, No. 3, 2007, p. 265-84.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Medicinal chemistry of competitive kainate receptor antagonists. / Larsen, Ann M; Bunch, Lennart.

    In: ACS Chemical Neuroscience, Vol. 2, No. 2, 16.02.2011, p. 60-74.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers. / Lappin, Graham ; Shishikura, Yoko; Jochemsen, Roeline; Weaver, Richard John ; Gesson, Charlotte; Houston, J. Brian ; Oosterhuis, Berend; Bjerrum, Ole Jannik; Grynkiewicz, Grzegorz; Alder, Jane; Rowland, Malcolm; Garner, Colin.

    In: European Journal of Pharmaceutical Sciences, Vol. 43, No. 3, 20.04.2011, p. 141-150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Methods for structural characterization of prefibrillar intermediates and amyloid fibrils. / Langkilde, Annette Eva; Vestergaard, Bente.

    In: FEBS Letters, Vol. 583, No. 16, 2009, p. 2600-2609.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Electron transfer reactivity of type zero Pseudomonas aeruginosa asurin. / Lancaster, Kyle M.; Farver, Ole; Wherland, Scot ; Crane, Edward J.; Richards, John H.; Pecht, Israel; Gray, Harry B.

    In: Journal of the American Chemical Society, Vol. 133, No. 13, 2011, p. 4865-4873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Identification of natural products using HPLC-SPE combined with CapNMR. / Lambert, Maja; Wolfender, Jean-Luc; Stærk, Dan; Christensen, Søren Brøgger; Hostettmann, Kurt; Jaroszewski, Jerzy Witold.

    In: Analytical Chemistry, Vol. 79, No. 2, 2007, p. 727-735.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors. / Lager, Erik; Nilsson, Jakob; Nielsen, Elsebet Østergaard; Nielsen, Mogens Peter Cherly; Liljefors, Tommy; Sterner, Olov.

    In: Bioorganic & Medicinal Chemistry, Vol. 16, No. 14, 2008, p. 6936-6948.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The use of Xenopus oocytes in drug screening. / Kvist, Trine; Hansen, Kasper Bø; Bräuner-Osborne, Hans.

    In: Expert Opinion on Drug Discovery, Vol. 6, No. 2, 2011, p. 141-153.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    The four human ¿-aminobutyric acid (GABA) transporters : pharmacological characterization and validation of a highly efficient screening assay. / Kvist, Trine; Christiansen, Bolette; Jensen, Anders Asbjørn; Bräuner-Osborne, Hans.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 12, No. 3, 2009, p. 241-249.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    STELLA software as a tool for modelling phosphorus removal in a constructed wetland employing dewatered alum sludge as main substrate. / Kumar, J. L. G.; Wang, Z. Y.; Babatunde, A. O.; Zhao, X. H.; Jørgensen, Sven Erik.

    In: Journal of Environmental Science and Health. Part A: Toxic Hazardous Substances and Environmental Engineering, Vol. 46, No. 7, 2011, p. 751-757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Flavylium salts as in vitro precursors of potent ligands to brain GABA-A receptors. / Kueny-Stotz, Marie; Chassaing, Stefan; Brouillard, Raymond; Nielsen, Mogens Peter Cherly; Goeldner, Maurice.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 18, No. 17, 2008, p. 4864-4867.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor. / Krzywkowski, Karen Margrethe; Davies, Paul A.; Feinberg-Zadek, Paula L.; Bräuner-Osborne, Hans; Jensen, Anders Asbjørn.

    In: Proceedings of the National Academy of Science of the United States of America, Vol. 105, No. 2, 2008, p. 722-727.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    En genetisk variation i en serotonin-receptor : et muligt link til depression? / Krzywkowski, Karen Margrethe; Davies, Paul A.; Feinberg-Zadek, Paula L.; Jensen, Anders Asbjørn; Bräuner-Osborne, Hans.

    In: Lægemiddelforskning, 2007, p. 30-31.

    Research output: Contribution to journalJournal articleCommunication

  33. Published

    Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling. / Krzywkowski, Karen Margrethe; Davies, Paul A.; Irving, Andrew J.; Bräuner-Osborne, Hans; Jensen, Anders Asbjørn.

    In: Pharmacogenetics and Genomics (Print Edition), Vol. 18, No. 12, 2008, p. 1027-1040.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression. / Krzywkowski, Karen Margrethe; Jensen, Anders Asbjørn; Connolly, Christopher N.; Bräuner-Osborne, Hans.

    In: Pharmacogenetics and Genomics (Print Edition), Vol. 17, No. 4, 2007, p. 255-266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Human 5-HT3 receptors : implications of genetic variations, chaperone proteins, and subunit concatenation on function and expression. / Krzywkowski, Karen Margrethe.

    København : Det Farmaceutiske Fakultet, 2008. 100 p.

    Research output: Book/ReportPh.D. thesis

  36. Published

    Scientific social responsibility : a call to arms. / Krogsgaard-Larsen, Povl; Thostrup, Peter; Besenbacher, Flemming.

    In: Angewandte Chemie International Edition, Vol. 50, No. 46, 11.11.2011, p. 10738-10740.

    Research output: Contribution to journalComment/debateResearch

  37. Published

    Textbook of drug design and discovery. / Krogsgaard-Larsen, Povl; Strømgaard, Kristian; Madsen, Ulf.

    4 ed. Boca Raton : CRC Press, 2010. 460 p.

    Research output: Book/ReportBook

  38. Published

    Introduction to drug design and discovery. / Krogsgaard-Larsen, Povl; Bunch, Lennart.

    Textbook of drug design and discovery. ed. / Povl Krogsgaard-Larsen; Kristian Strømgaard; Ulf Madsen. 4. ed. Boca Raton : CRC Press, 2010. p. 1-13.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  39. Published

    Carbene mediated C-H insertion into phenyl piperazine and analogous structures : an approach to synthesise polycyclic, neuroactive scaffolds. / Krogsgaard-Larsen, Niels.

    København : Det Farmaceutiske Fakultet, 2010. 235 p.

    Research output: Book/ReportPh.D. thesis

  40. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion. / Krogsgaard-Larsen, Niels; Begtrup, Mikael; Frydenvang, Karla Andrea; Kehler, Jan .

    In: Tetrahedron, Vol. 66, No. 47, 20.11.2010, p. 9297-9303.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands. / Krogsgaard-Larsen, Niels; Jensen, Anders A.; Kehler, Jan.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 20, No. 18, 15.09.2010, p. 5431-5433.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Simultaneous determination of cytosine arabinoside, daunorubicin and etoposide in human plasma. / Krogh-Madsen, Mikkel; Hansen, Steen Honoré; Honoré, Per Hartvig.

    In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, Vol. 878, No. 22, 2010, p. 1967-72.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Analysis of the dissipation kinetics of ivermectin at different temperatures and in four different soils. / Krogh, Kristine Andersen; Jensen, Gitte Gotholdt; Schneider, Manuel K.; Fenner, Kathrin; Halling-Sørensen, Bent.

    In: Chemosphere, Vol. 75, 2009, p. 1097-1104.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry. / Krogh, Kristine Andersen; Björklund, Bengt Erland; Loeffler, D.; Fink, G.; Halling-Sørensen, Bent; Ternes, T.A.

    In: Journal of Chromatography A, Vol. 1211, No. 1-2, 2008, p. 60-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Sorption and mobility of ivermectin in different soils. / Krogh, Kristine Andersen; Søborg, Tue; Larsen, Birger Brodin; Halling-Sørensen, Bent.

    In: Journal of Environmental Quality, Vol. 37, No. 6, 2008, p. 2202-2211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Veterinære lægemidler i natur og miljø : Er miljørisikovurdering god nok ? / Krogh, Kristine Andersen; Anskjær, Gitte Gotholdt; Halling-Sørensen, Bent.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 52-54.

    Research output: Contribution to journalJournal articleResearch

  47. Published

    Tighten the concepts of oecd 106 and 307 to assess the fate of veterinary medicines. / Krogh, Kristine Andersen; Jensen, G. G.; Sporring, Sune Hove; Halling-Sørensen, Bent.

    2007. Abstract from International conference on  Pharmaceuticals in the Environment, York, United Kingdom.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  48. Published

    Access to health care in relation to socioeconomic status in the Amazonian area of Peru. / Kristiansson, Charlotte; Gotuzzo, Eduardo; Rodriguez, Hugo; Bartoloni, Alessandro; Strohmeyer, Marianne; Tomson, Göran; Hartvig, Per.

    In: International Journal for Equity in Health, Vol. 8, 2009, p. 11-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp. / Kristensen, Ole; Ross, Birthe; Gajhede, Michael.

    In: Journal of Molecular Biology, Vol. 375, No. 5, 2008, p. 1469-1476.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Stressfremkaldende hjerneaktivitet kan nu undersøges i realtid. / Kristensen, Morten Pilgaard.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 40-42.

    Research output: Contribution to journalJournal articleCommunication

  51. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor. / Kristensen, Line Hyltoft; Nielsen, Anders Laerke; Helgstrand, Charlotte; Lees, Michael; Cloos, Paul; Kastrup, Jette Sandholm; Helin, Kristian; Olsen, Lars; Gajhede, Michael.

    In: F E B S Journal, Vol. 279, No. 11, 06.2012, p. 1905-1914.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors. / Kristensen, Line Hyltoft.

    København : Faculty of Health and Medical Sciences, University of Copenhagen, 2012. 168 p.

    Research output: Book/ReportPh.D. thesis

  53. Published

    Histonhaler : et nyt mål inden for kræftbehandling. / Kristensen, Jesper Langgaard; Lohse, Brian; Clausen, Rasmus Prætorius.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  54. Published

    Synthesis of RHPS4 via an anionic ring closing cascade. / Kristensen, Jesper Langgaard.

    In: Tetrahedron Letters, Vol. 49, No. 15, 2008, p. 2351-2354.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Exploring the neuroleptic substituent in octoclothepin : potential ligands for positron emission tomography with subnanomolar affinity for alpha1-adrenoceptors. / Kristensen, Jesper Langgaard; Pu¨schl, Ask; Jensen, Martin; Risgaard, Rune; Christoffersen, Claus T; Bang-Andersen, Benny; Balle, Thomas.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 19, 2010, p. 7021-7034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil. / Kristensen, Janni Brogaard; Jørgensen, Henry; Mu, Huiling.

    In: European Journal of Lipid Science and Technology, Vol. 114, No. 2, 2012, p. 146-152.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A : Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases. / Kristensen, Jan B L; Nielsen, Anders L; Jørgensen, Lars; Kristensen, Line Hyltoft; Helgstrand, Charlotte; Juknaite, Lina; Kristensen, Jesper Langgaard; Kastrup, Jette Sandholm; Clausen, Rasmus Prætorius; Olsen, Lars; Gajhede, Michael.

    In: F E B S Letters, Vol. 585, No. 12, 23.06.2011, p. 1951-1956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    On-line monitoring of the dynamics of trihalomethane concentrations in a warm public swimming pool using an unsupervised membrane inlet mass spectrometry system with off-site real-time surveillance. / Kristensen, Gert H.; Klausen, Morten M.; Hansen, Vagn A.; Lauritsen, Frants Roager.

    In: Rapid Communications in Mass Spectrometry, Vol. 24, No. 1, 2010, p. 30-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating. / Kristensen, Anders Skov; Jenkins, Meagan A; Banke, Tue G; Schousboe, Arne; Makino, Yuichi; Johnson, Richard C; Huganir, Richard; Traynelis, Stephen F.

    In: Nature Neuroscience, Vol. 14, No. 6, 01.06.2011, p. 727-735.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Structural correlates of ionotropic glutamate receptor function. / Kristensen, Anders Skov; Hansen, Kasper Bø; Wollmuth, Lonnie P.; Egebjerg, Jan; Traynelis, Stephen F.

    The receptors: The glutamate receptors. ed. / R. W. Gereau; G. T. Swanson. 1. ed. Totowa N.J., USA : Humana Press, 2007. p. 247-299.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  61. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development. / Krishna, Rajesh; Schaefer, Hans Guenter; Bjerrum, Ole Jannik.

    In: European Journal of Pharmaceutical Sciences, Vol. 31, No. 1, 2007, p. 62-67.

    Research output: Contribution to journalLetterResearch

  62. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2. / Krintel, Christian; Frydenvang, Karla; Olsen, Lars; Kristensen, Maria T; de Barrios, Oriol; Naur, Peter; Francotte, Pierre; Pirotte, Bernard; Gajhede, Michael; Kastrup, Jette Sandholm.

    In: Biochemical Journal, Vol. 441, No. 1, 01.01.2012, p. 173-178.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs. / Krall, Jacob; Jensen, Claus Hatt; Bavo, Francesco; Falk-Petersen, Christina Birkedahl; Haugaard, Anne Stæhr; Vogensen, Stine Byskov; Tian, Yongsong; Nittegaard-Nielsen, Mia; Sigurdardóttir, Sara Björk; Kehler, Jan; Kongstad, Kenneth Thermann; Gloriam, David E.; Clausen, Rasmus Prætorius; Harpsøe, Kasper; Wellendorph, Petrine; Frølund, Bente.

    In: Journal of Medicinal Chemistry, Vol. 60, No. 21, 2017, p. 9022-9039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Stress and medicine use for headache: does sense of coherence modify the association? / Koushede, Vibeke Jenny; Holstein, Bjørn E; Andersen, Anette; Hansen, Ebba Holme.

    In: European Journal of Public Health, Vol. 21, No. 5, 01.10.2011, p. 656-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Medicine use for headache : the effect of social class, stress and sense of coherence. / Koushede, Vibeke Jenny; Holstein, Bjørn; Andersen, Anette; Hansen, Ebba Holme.

    In: International Journal of Behavioral Medicine, Vol. 17, No. Suppl. 1, 2010, p. s139.

    Research output: Contribution to journalConference abstract in journalResearch

  66. Published

    Stress kan fordoble risikoen for at bruge smertestillende medicin. / Koushede, Vibeke Jenny; Hansen, Ebba Holme.

    In: Lægemiddelforskning, Vol. 2010, 2010, p. 37-39.

    Research output: Contribution to journalJournal articleResearch

  67. Published

    Use of over-the-counter analgesics and perceived stress among 25-44-year olds. / Koushede, Vibeke; Holstein, Bjørn E; Andersen, Anette; Ekholm, Ola; Hansen, Ebba Holme.

    In: Pharmacoepidemiology and Drug Safety, Vol. 19, 2010, p. 351-357.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Phase transformations of amlodipine besylate solid forms. / Koradia, Vishal Shamji; Lemos, Ana Filipa Fontelonga de; Allesø, Morten; Diego, Heidi Lopez de; Ringkjøbing-Elema, Michiel; Müllertz, Anette; Rantanen, Jukka Tapio.

    In: Journal of Pharmaceutical Sciences, Vol. 100, No. 7, 2011, p. 2896-2910.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction. / Koradia, Vishal Shamji; Tenho, Mikko; Diego, Heidi Lopez de; Ringkjøbing-Elma, Michiel ; Sonnergaard, Jørn; Salonen, Jamo; Lehto, Vesa-Pekka; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 29, No. 1, 2012, p. 134-144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Integrated approach to study the dehydration kinetics of nitrofurantoin monohydrate. / Koradia, Vishal Shamji; Diego, Heidi Lopez De; Elema, Michiel Ringkjøbing; Rantanen, Jukka Tapio.

    In: Journal of Pharmacy and Pharmaceutical Sciences, Vol. 99, No. 9, 2010, p. 3966-3976.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Solid forms of amlodipine besylate : Physiochemical, structural, and thermodynamic characterization. / Koradia, Vishal Shamji; Lopez de Diego, Heidi; Frydenvang, Karla Andrea; Ringkjøbing-Elema, Michiel; Müllertz, Anette; Bond, Andrew; Rantanen, Jukka.

    In: Crystal Growth & Design, Vol. 10, No. 12, 28.10.2010, p. 5279-5290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Solid forms of amlodipine besylate : Physiochemical, structural, and thermodynamic characterization. / Koradia, Vishal Shamji; Lopez de Diego, Heidi; Frydenvang, Karla Andrea; Ringkjøbing-Elema, Michiel; Müllertz, Anette; Bond, Andrew D; Rantanen, Jukka.

    In: Crystal Growth & Design, Vol. 10, No. 12, 28.10.2010, p. 5279-5290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: Implications for control of behavioral state. / Kohlmeier, Kristi Anne; Kristiansen, Uffe.

    In: Journal of Neuroscience, 2009.

    Research output: Contribution to journalConference abstract in journalResearch

  74. Published

    Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration. / Kogermann, Karin; Aaltonen, Jaakko; Strachan, Clare J.; Pöllänen, Kati; Heinämäki, Jyrki; Yliruusi, Jouko; Rantanen, Jukka Tapio.

    In: Journal of Pharmaceutical Sciences, Vol. 97, No. 11, 2008, p. 4983-4999.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling. / Kogermann, Karin; Aaltonen, Jaakko; Strachan, Clare J.; Pöllänen, Kati; Veski, Peep; Heinämäki, Jyrki; Yliruusi, Jouko; Rantanen, Jukka Tapio.

    In: Journal of Pharmaceutical Sciences, Vol. 96, No. 7, 2007, p. 1802-1820.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Investigating dehydration from compacts using terahertz pulsed, raman, and near-infrared spectroscopy. / Kogermann, Karin; Zeitler, Axel J.; Rantanen, Jukka Tapio; Rades, Thomas; Taday, Phillip F.; Pepper, Michael; Heinämäki, Jyrki; Strachan, Clare J.

    In: Applied Spectroscopy, Vol. 61, No. 12, 2007, p. 1265-1274.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    X-ray powder diffractormetry in combination with principal component analysis - A tool for monitoring solid state changes. / Kogermann, Karin; Veski, Peep; Rantanen, Jukka Tapio; Naelapaa, Kaisa.

    In: European Journal of Pharmaceutical Sciences, Vol. 43, 2011, p. 278-289.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Comparison of vibrational spectroscopy techniques to investigate the dehydration behaviour of piroxicam monohydrate from compacts. / Kogermann, K.; Zeitler, J.A.; Rantanen, Jukka Tapio; Rades, T.; Taday, P.F.; Pepper, M.; Heinämäki, J.; Strachan, C.J.

    In: Ecological Modelling, Vol. 32S, No. 1, 2007, p. S9-S9.

    Research output: Contribution to journalConference abstract in journalResearch

  79. Published

    Iron supplement use among Danish pregnant women. / Knudsen, Vibeke K.; Hansen, Harald S.; Ovesen, Lars; Mikkelsen, Tina B.; Olsen, Sjurour F.

    In: Public Health Nutrition, Vol. 10, No. 10, 2007, p. 1104-1110.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Penetration of gel and liquid state liposomes into barrier-impaired skin. / Knudsen, Nina Østergaard; Frøkjær, Sven; Hansen, J.; Jørgensen, Lene; Foged, Camilla.

    In: Journal of Pharmacy and Pharmacology, 2010, p. 793.

    Research output: Contribution to journalConference articleResearchpeer-review

  81. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor. / Knudsen, Nina Østergaard; Schiffelers, Raymond M.; Jørgensen, Lene; Hansen, Jens; Frøkjær, Sven; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 428, No. 1-2, 2012, p. 171-177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Targeting of liposome-associated calcipotriol to the skin : effect of liposomal membrane fluidity and skin barrier integrity. / Knudsen, Nina Østergaard; Jørgensen, Lene; Hansen, Jens; Vermehren, Charlotte; Frøkjær, Sven; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 416, 2011, p. 478-485.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Ledelse og organisation på de danske apoteker. / Klinke, Bjørn Ove.

    København : Det Farmaceutiske Fakultet, 2007. 279 p.

    Research output: Book/ReportPh.D. thesis

  84. Published

    In vitro responses of parvocellular paraventricular hypothalamus neurons to neuroactive agents. / Klein, Jessica; Hoang, Trang; Kohlmeier, Kristi Anne; Kristensen, Morten Pilgaard.

    2011. Poster session presented at 2011 EGE Neuroendocrinology Meeting, Turkey.

    Research output: Contribution to conferencePosterResearch

  85. Published

    Knockdown of GDH indicates its potential impact in sustaining glutamate homeostasis and neurotransmission. / Klawonn, Anna M.; Bolanos, J. P.; Waagepetersen, Helle S.; Schousboe, Arne.

    In: Journal of Neurochemistry, No. s2, 2009, p. 105.

    Research output: Contribution to journalConference abstract in journalResearch

  86. Published

    Leaching of estrogenic hormones from manure-treated structured soils. / Kjær, Jeanne; Olsen, Preben; Bach, Kamilla; Barlebo, Heidi C.; Ingerslev, Flemming; Hansen, Martin; Halling-Sørensen, Bent.

    In: Environmental Science & Technology (Washington), Vol. 41, No. 11, 2007, p. 3911-3917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic canser by FISH. / Kirkegaard, Tove; Witton, Caroline J.; Edwards, Joanne; Nielsen, Kirsten Vang; Jensen, Linda Boye; Campbell, Fiona M.; Cooke, Timothy G.; Bartlett, John M. S.

    In: Histopathology, Vol. 2010, No. 56, 2010, p. 203-211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance. / Kilts, T; Ameye, L; Syed-Picard, F; Ono, M; Berendsen, A. D.; Oldberg, A.; Heegaard, Anne-Marie; Bi, Y.; Young, M F.

    In: Scandinavian Journal of Medicine & Science in Sports Online, Vol. 19, No. 4, 2009, p. 536-46.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell. / Khalid, Sami A.; Friedrichsen, Gerda M.; Christensen, Søren Brøgger; El Tahir, Ahmed; Satti, Gwiria M.

    In: ARKIVOC, No. ix, 2007, p. 129-134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Sample preparation in membrane introduction mass spectrometry : fundamental extraction techniques. / Ketola, Raimo A.; Kotiaho, Tapio; Lauritsen, Frants Roager.

    Handbook of sample preparation. ed. / Janusz Pawlizyn; Heather L. Lord. Hoboken : Wiley, 2010. p. 149-162.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  91. Published

    Hyphenated NMR techniques. / Kesting, Julie Regitze; Johansen, Kenneth T; Jaroszewski, Jerzy W.

    Biomolecular NMR spectroscopy. ed. / Andrew J Dingley; Steven M Pascal. Vol. 3 Amsterdam : IOS Press, 2011. p. 413-434 (Advances in biomedical spectroscopy, Vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  92. Published

    Nu kan forfalskede lægemidler afsløres. / Kesting, Julie Regitze; Adsersen, Anne; Gudiksen, Lene.

    In: Lægemiddelforskning, Vol. 2010, 12.2010, p. 4-6.

    Research output: Contribution to journalJournal articleCommunication

  93. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures : HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study. / Kesting, Julie Regitze; Olsen, Lars; Stærk, Dan; Tejesvi, Mysore V; Kini, Kukkundoor R; Prakash, Harishchandra S; Jaroszewski, Jerzy W.

    In: Journal of Natural Products, Vol. 74, No. 10, 26.09.2011, p. 2206-2215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Identification of adulterants in a Chinese herbal medicine by LC-HRMS and LC-MS-SPE/NMR and comparative in vivo study with standards in a hypertensive rat model. / Kesting, Julie Regitze; Huang, JingQi; Sørensen, Dan.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 51, No. 3, 2010, p. 705-711.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    HPLC-MS-SPE-NMR and other modern instrumental techniques in analysis af complex natural products mixtures. / Kesting, Julie Regitze.

    København : Det Farmaceutiske Fakultet, 2010. 152 p.

    Research output: Book/ReportPh.D. thesis

  96. Published

    Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy. / Keiding, Susanne; Iversen, P.; Sørensen, M.; Bak, Lasse Kristoffer; Waagepetersen, Helle S.; Gjedde, Albert; Schousboe, Arne; Vilstrup, Hendrik.

    In: Journal of Neurochemistry, No. s1, 2009, p. 269-270.

    Research output: Contribution to journalConference abstract in journalResearch

  97. Published

    Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4. / Kayser, O.; Julsing, M. K.; Vasilev, N. P.; Schneidman-Duhovny, D.; Koulman, A.; Clarkson, Cailean; Woerdenbag, H. J.; Ionkova, I.; Wolfson, H. J.; Bos, R.; Muntendam, R.; Jaroszewski, Jerzy Witold; Quax, W. J.

    In: Planta Medica, Vol. 74, No. 9, 2008, p. 925 (SL74).

    Research output: Contribution to journalConference abstract in journalResearch

  98. Published

    Brug biblioteket - find informationen : kompendium i biblioteksvejledning og informationssøgning. / Kastrup, Eva Hjorth; Kristiansen, Dorthe; Kaad, Lene; Weile, Martin.

    København : Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet, 2008.

    Research output: Book/ReportCompendium/lecture notes

  99. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 . / Kasper, Christina; Frydenvang, Karla Andrea; Naur, Peter; Gajhede, Michael; Pickering, Darryl S; Kastrup, Jette Sandholm Jensen.

    In: FEBS Letters, Vol. 582, No. 29, 2008, p. 4089-4094.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    On the temperature dependence of complex formation between chitosan and proteins. / Kasimova, Marina Robertovna; Valázquez-Campoy, Adrián ; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 12, No. 7, 2011, p. 2534-2543.

    Research output: Contribution to journalJournal articleResearchpeer-review

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