Research areas

  1. Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, K. A., Ringkjøbing-Elema, M., Müllertz, A., Bond, Andrew & Rantanen, J., 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Use of over-the-counter analgesics and perceived stress among 25-44-year olds

    Koushede, V., Holstein, B. E., Andersen, A., Ekholm, O. & Hansen, E. H., 2010, In : Pharmacoepidemiology and Drug Safety. 19, p. 351-357

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Stress and medicine use for headache: does sense of coherence modify the association?

    Koushede, V. J., Holstein, B. E., Andersen, A. & Hansen, E. H., 1 Oct 2011, In : European Journal of Public Health. 21, 5, p. 656-61 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Medicine use for headache: the effect of social class, stress and sense of coherence

    Koushede, V. J., Holstein, B., Andersen, A. & Hansen, E. H., 2010, In : International Journal of Behavioral Medicine. 17, Suppl. 1, p. s139

    Research output: Contribution to journalConference abstract in journalResearch

  6. Published

    Stress kan fordoble risikoen for at bruge smertestillende medicin

    Koushede, V. J. & Hansen, E. H., 2010, In : Lægemiddelforskning. 2010, p. 37-39

    Research output: Contribution to journalJournal articleResearch

  7. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, Christina Birkedahl, Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development

    Krishna, R., Schaefer, H. G. & Bjerrum, Ole Jannik, 2007, In : European Journal of Pharmaceutical Sciences. 31, 1, p. 62-67

    Research output: Contribution to journalLetterResearch

  10. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In : Nature Neuroscience. 14, 6, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structural correlates of ionotropic glutamate receptor function

    Kristensen, Anders Skov, Hansen, K. B., Wollmuth, L. P., Egebjerg, J. & Traynelis, S. F., 2007, The receptors: The glutamate receptors. Gereau, R. W. & Swanson, G. T. (eds.). 1. ed. Totowa N.J., USA: Humana Press, p. 247-299 42 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  12. Published

    On-line monitoring of the dynamics of trihalomethane concentrations in a warm public swimming pool using an unsupervised membrane inlet mass spectrometry system with off-site real-time surveillance

    Kristensen, G. H., Klausen, M. M., Hansen, V. A. & Lauritsen, F. R., 2010, In : Rapid Communications in Mass Spectrometry. 24, 1, p. 30-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil

    Kristensen, J. B., Jørgensen, H. & Mu, Huiling, 2012, In : European Journal of Lipid Science and Technology. 114, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  16. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In : Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for alpha1-adrenoceptors

    Kristensen, Jesper Langgaard, Pu¨schl, A., Jensen, M., Risgaard, R., Christoffersen, C. T., Bang-Andersen, B. & Balle, T., 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7021-7034

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, Paul, Kastrup, Jette Sandholm Jensen, Helin, Kristian, Olsen, L. & Gajhede, Michael, Jun 2012, In : F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Stressfremkaldende hjerneaktivitet kan nu undersøges i realtid

    Kristensen, M. P., 2010, In : Lægemiddelforskning. 2010, p. 40-42

    Research output: Contribution to journalJournal articleCommunication

  21. Published

    Structure of the PPX/GPPA phosphatase from Aquifex aeolicus in complex with the alarmone ppGpp

    Kristensen, O., Ross, B. & Gajhede, Michael, 2008, In : Journal of Molecular Biology. 375, 5, p. 1469-1476

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Access to health care in relation to socioeconomic status in the Amazonian area of Peru

    Kristiansson, C., Gotuzzo, E., Rodriguez, H., Bartoloni, A., Strohmeyer, M., Tomson, G. & Hartvig, P., 2009, In : International Journal for Equity in Health. 8, p. 11-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Analysis of the dissipation kinetics of ivermectin at different temperatures and in four different soils

    Krogh, K. A., Jensen, G. G., Schneider, M. K., Fenner, K. & Halling-Sørensen, B., 2009, In : Chemosphere. 75, p. 1097-1104

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry

    Krogh, K. A., Björklund, B. E., Loeffler, D., Fink, G., Halling-Sørensen, B. & Ternes, T. A., 2008, In : Journal of Chromatography A. 1211, 1-2, p. 60-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Sorption and mobility of ivermectin in different soils

    Krogh, K. A., Søborg, T., Brodin, Birger & Halling-Sørensen, B., 2008, In : Journal of Environmental Quality. 37, 6, p. 2202-2211

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Veterinære lægemidler i natur og miljø: Er miljørisikovurdering god nok ?

    Krogh, K. A., Anskjær, G. G. & Halling-Sørensen, B., 2010, In : Lægemiddelforskning. 2010, p. 52-54

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Tighten the concepts of oecd 106 and 307 to assess the fate of veterinary medicines

    Krogh, K. A., Jensen, G. G., Sporring, S. H. & Halling-Sørensen, B., 2007.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  28. Published

    Simultaneous determination of cytosine arabinoside, daunorubicin and etoposide in human plasma

    Krogh-Madsen, M., Hansen, S. H. & Honoré, P. H., 2010, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 878, 22, p. 1967-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Carbene mediated C-H insertion into phenyl piperazine and analogous structures: an approach to synthesise polycyclic, neuroactive scaffolds

    Krogsgaard-Larsen, N., 2010, København: Det Farmaceutiske Fakultet. 235 p.

    Research output: Book/ReportPh.D. thesisResearch

  30. Published

    Syntheses of aza-analogous iso-ergoline scaffolds using carbene mediated C-H insertion

    Krogsgaard-Larsen, N., Begtrup, M., Frydenvang, Karla Andrea & Kehler, J., 20 Nov 2010, In : Tetrahedron. 66, 47, p. 9297-9303

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indoles as dual serotonin 5-HT2C and 5-HT6 receptor ligands

    Krogsgaard-Larsen, N., Jensen, Anders A. & Kehler, J., 15 Sep 2010, In : Bioorganic & Medicinal Chemistry Letters. 20, 18, p. 5431-5433

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Scientific social responsibility: a call to arms

    Krogsgaard-Larsen, Povl, Thostrup, P. & Besenbacher, F., 11 Nov 2011, In : Angewandte Chemie International Edition. 50, 46, p. 10738-10740

    Research output: Contribution to journalComment/debateResearch

  33. Published

    Textbook of drug design and discovery

    Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.

    Research output: Book/ReportBookEducation

  34. Published

    Introduction to drug design and discovery

    Krogsgaard-Larsen, Povl & Bunch, Lennart, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 1-13

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  35. Published

    High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Bräuner-Osborne, Hans & Jensen, Anders A., 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 2, p. 722-727

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    En genetisk variation i en serotonin-receptor: et muligt link til depression?

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Jensen, Anders A. & Bräuner-Osborne, Hans, 2007, In : Lægemiddelforskning. p. 30-31

    Research output: Contribution to journalJournal articleCommunication

  37. Published

    Characterization of the effects of four HTR3B polymorphisms on human 5-HT3AB receptor expression and signalling

    Krzywkowski, K. M., Davies, P. A., Irving, A. J., Bräuner-Osborne, Hans & Jensen, Anders A., 2008, In : Pharmacogenetics and Genomics (Print Edition). 18, 12, p. 1027-1040

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

    Krzywkowski, K. M., Jensen, Anders A., Connolly, C. N. & Bräuner-Osborne, Hans, 2007, In : Pharmacogenetics and Genomics (Print Edition). 17, 4, p. 255-266

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Human 5-HT3 receptors: implications of genetic variations, chaperone proteins, and subunit concatenation on function and expression

    Krzywkowski, K. M., 2008, København: Det Farmaceutiske Fakultet. 100 p.

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    Flavylium salts as in vitro precursors of potent ligands to brain GABA-A receptors

    Kueny-Stotz, M., Chassaing, S., Brouillard, R., Nielsen, M. P. C. & Goeldner, M., 2008, In : Bioorganic & Medicinal Chemistry Letters. 18, 17, p. 4864-4867

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    STELLA software as a tool for modelling phosphorus removal in a constructed wetland employing dewatered alum sludge as main substrate

    Kumar, J. L. G., Wang, Z. Y., Babatunde, A. O., Zhao, X. H. & Jørgensen, S. E., 2011, In : Journal of Environmental Science and Health. Part A: Toxic Hazardous Substances and Environmental Engineering. 46, 7, p. 751-757

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The use of Xenopus oocytes in drug screening

    Kvist, T., Hansen, K. B. & Bräuner-Osborne, Hans, 2011, In : Expert Opinion on Drug Discovery. 6, 2, p. 141-153

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    The four human ¿-aminobutyric acid (GABA) transporters: pharmacological characterization and validation of a highly efficient screening assay

    Kvist, T., Christiansen, B., Jensen, Anders A. & Bräuner-Osborne, Hans, 2009, In : Combinatorial Chemistry & High Throughput Screening. 12, 3, p. 241-249

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors

    Lager, E., Nilsson, J., Nielsen, E. Ø., Nielsen, M. P. C., Liljefors, T. & Sterner, O., 2008, In : Bioorganic & Medicinal Chemistry. 16, 14, p. 6936-6948

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Identification of natural products using HPLC-SPE combined with CapNMR

    Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In : Analytical Chemistry. 79, 2, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Electron transfer reactivity of type zero Pseudomonas aeruginosa asurin

    Lancaster, K. M., Farver, O., Wherland, S., Crane, E. J., Richards, J. H., Pecht, I. & Gray, H. B., 2011, In : Journal of the American Chemical Society. 133, 13, p. 4865-4873

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

    Langkilde, Annette Eva & Vestergaard, Bente, 2009, In : FEBS Letters. 583, 16, p. 2600-2609

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In : European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Medicinal chemistry of competitive kainate receptor antagonists

    Larsen, A. M. & Bunch, Lennart, 16 Feb 2011, In : ACS Chemical Neuroscience. 2, 2, p. 60-74

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    The impact of an automated dose-dispensing scheme on user compliance, medication understanding, and medication stockpiles

    Larsen, A. B. & Nørgaard, Lotte Stig, 2007, In : Research in Social and Administrative Pharmacy. 3, 3, p. 265-84

    Research output: Contribution to journalJournal articleResearchpeer-review