Research areas

  1. Published

    Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor

    Kristensen, L. H., Nielsen, A. L., Helgstrand, C., Lees, M., Cloos, Paul, Kastrup, Jette Sandholm Jensen, Helin, Kristian, Olsen, L. & Gajhede, Michael, Jun 2012, In : F E B S Journal. 279, 11, p. 1905-1914

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesisResearch

  3. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Synthesis of RHPS4 via an anionic ring closing cascade

    Kristensen, Jesper Langgaard, 2008, In : Tetrahedron Letters. 49, 15, p. 2351-2354

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Exploring the neuroleptic substituent in octoclothepin: potential ligands for positron emission tomography with subnanomolar affinity for alpha1-adrenoceptors

    Kristensen, Jesper Langgaard, Pu¨schl, A., Jensen, M., Risgaard, R., Christoffersen, C. T., Bang-Andersen, B. & Balle, T., 2010, In : Journal of Medicinal Chemistry. 53, 19, p. 7021-7034

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Absorption difference between diacylglycerol oil and butter blend containing deacylglycerol oil

    Kristensen, J. B., Jørgensen, H. & Mu, Huiling, 2012, In : European Journal of Lipid Science and Technology. 114, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases

    Kristensen, J. B. L., Nielsen, A. L., Jørgensen, L., Kristensen, L. H., Helgstrand, C., Juknaite, L., Kristensen, Jesper Langgaard, Kastrup, Jette Sandholm Jensen, Clausen, Rasmus Prætorius, Olsen, L. & Gajhede, Michael, 23 Jun 2011, In : F E B S Letters. 585, 12, p. 1951-1956

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    On-line monitoring of the dynamics of trihalomethane concentrations in a warm public swimming pool using an unsupervised membrane inlet mass spectrometry system with off-site real-time surveillance

    Kristensen, G. H., Klausen, M. M., Hansen, V. A. & Lauritsen, F. R., 2010, In : Rapid Communications in Mass Spectrometry. 24, 1, p. 30-34

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In : Nature Neuroscience. 14, 6, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural correlates of ionotropic glutamate receptor function

    Kristensen, Anders Skov, Hansen, K. B., Wollmuth, L. P., Egebjerg, J. & Traynelis, S. F., 2007, The receptors: The glutamate receptors. Gereau, R. W. & Swanson, G. T. (eds.). 1. ed. Totowa N.J., USA: Humana Press, p. 247-299 42 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development

    Krishna, R., Schaefer, H. G. & Bjerrum, Ole Jannik, 2007, In : European Journal of Pharmaceutical Sciences. 31, 1, p. 62-67

    Research output: Contribution to journalLetterResearch

  12. Published

    Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2

    Krintel, C., Frydenvang, Karla Andrea, Olsen, L., Kristensen, M. T., de Barrios, O., Naur, P., Francotte, P., Pirotte, B., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 1 Jan 2012, In : Biochemical Journal. 441, 1, p. 173-178

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs

    Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, Christina Birkedahl, Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In : Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Stress and medicine use for headache: does sense of coherence modify the association?

    Koushede, V. J., Holstein, B. E., Andersen, A. & Hansen, Ebba Holme, 1 Oct 2011, In : European Journal of Public Health. 21, 5, p. 656-61 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Medicine use for headache: the effect of social class, stress and sense of coherence

    Koushede, V. J., Holstein, B., Andersen, A. & Hansen, Ebba Holme, 2010, In : International Journal of Behavioral Medicine. 17, Suppl. 1, p. s139

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Stress kan fordoble risikoen for at bruge smertestillende medicin

    Koushede, V. J. & Hansen, Ebba Holme, 2010, In : Lægemiddelforskning. 2010, p. 37-39

    Research output: Contribution to journalJournal articleResearch

  17. Published

    Use of over-the-counter analgesics and perceived stress among 25-44-year olds

    Koushede, V., Holstein, B. E., Andersen, A., Ekholm, O. & Hansen, Ebba Holme, 2010, In : Pharmacoepidemiology and Drug Safety. 19, p. 351-357

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Phase transformations of amlodipine besylate solid forms

    Koradia, V. S., Lemos, A. F. F. D., Allesø, M., Diego, H. L. D., Ringkjøbing-Elema, M., Mullertz, Anette & Rantanen, Jukka, 2011, In : Journal of Pharmaceutical Sciences. 100, 7, p. 2896-2910

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction

    Koradia, V. S., Tenho, M., Diego, H. L. D., Ringkjøbing-Elma, M., Sonnergaard, J., Salonen, J., Lehto, V. & Rantanen, Jukka, 2012, In : Pharmaceutical Research. 29, 1, p. 134-144

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Integrated approach to study the dehydration kinetics of nitrofurantoin monohydrate

    Koradia, V. S., Diego, H. L. D., Elema, M. R. & Rantanen, Jukka, 2010, In : Journal of Pharmacy and Pharmaceutical Sciences. 99, 9, p. 3966-3976

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, K. A., Ringkjøbing-Elema, M., Müllertz, A., Bond, Andrew & Rantanen, J., 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Solid forms of amlodipine besylate: Physiochemical, structural, and thermodynamic characterization

    Koradia, V. S., Lopez de Diego, H., Frydenvang, Karla Andrea, Ringkjøbing-Elema, M., Mullertz, Anette , Bond, A. D. & Rantanen, Jukka, 28 Oct 2010, In : Crystal Growth & Design. 10, 12, p. 5279-5290

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: Implications for control of behavioral state

    Kohlmeier, Kristi Anne & Kristiansen, Uffe, 2009, In : Journal of Neuroscience.

    Research output: Contribution to journalConference abstract in journalResearch

  24. Published

    Establishing quantitative in-line analysis of multiple solid-state transformations during dehydration

    Kogermann, K., Aaltonen, J., Strachan, C. J., Pöllänen, K., Heinämäki, J., Yliruusi, J. & Rantanen, Jukka, 2008, In : Journal of Pharmaceutical Sciences. 97, 11, p. 4983-4999

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Qualitative in situ analysis of multiple solid-state forms using spectroscopy and partial least squares discriminant modeling

    Kogermann, K., Aaltonen, J., Strachan, C. J., Pöllänen, K., Veski, P., Heinämäki, J., Yliruusi, J. & Rantanen, Jukka, 2007, In : Journal of Pharmaceutical Sciences. 96, 7, p. 1802-1820

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Investigating dehydration from compacts using terahertz pulsed, raman, and near-infrared spectroscopy

    Kogermann, K., Zeitler, A. J., Rantanen, Jukka, Rades, Thomas, Taday, P. F., Pepper, M., Heinämäki, J. & Strachan, C. J., 2007, In : Applied Spectroscopy. 61, 12, p. 1265-1274

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    X-ray powder diffractormetry in combination with principal component analysis - A tool for monitoring solid state changes

    Kogermann, K., Veski, P., Rantanen, Jukka & Naelapaa, K., 2011, In : European Journal of Pharmaceutical Sciences. 43, p. 278-289

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Comparison of vibrational spectroscopy techniques to investigate the dehydration behaviour of piroxicam monohydrate from compacts

    Kogermann, K., Zeitler, J. A., Rantanen, Jukka, Rades, T., Taday, P. F., Pepper, M., Heinämäki, J. & Strachan, C. J., 2007, In : Ecological Modelling. 32S, 1, p. S9-S9

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    Iron supplement use among Danish pregnant women

    Knudsen, V. K., Hansen, Harald S., Ovesen, L., Mikkelsen, T. B. & Olsen, S. F., 2007, In : Public Health Nutrition. 10, 10, p. 1104-1110

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Penetration of gel and liquid state liposomes into barrier-impaired skin

    Knudsen, N. Ø., Frøkjær, Sven, Hansen, J., Jørgensen, Lene & Foged, Camilla, 2010, In : Journal of Pharmacy and Pharmacology. p. 793

    Research output: Contribution to journalConference articleResearchpeer-review

  31. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

    Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In : International Journal of Pharmaceutics. 428, 1-2, p. 171-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity

    Knudsen, N. Ø., Jørgensen, Lene, Hansen, J., Vermehren, C., Frøkjær, Sven & Foged, Camilla, 2011, In : International Journal of Pharmaceutics. 416, p. 478-485

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Ledelse og organisation på de danske apoteker

    Klinke, B. O., 2007, København: Det Farmaceutiske Fakultet. 279 p.

    Research output: Book/ReportPh.D. thesisResearch

  34. Published

    In vitro responses of parvocellular paraventricular hypothalamus neurons to neuroactive agents

    Klein, J., Hoang, T., Kohlmeier, Kristi Anne & hrx301, hrx301, 2011.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Knockdown of GDH indicates its potential impact in sustaining glutamate homeostasis and neurotransmission

    Klawonn, A. M., Bolanos, J. P., Waagepetersen, Helle S. & Schousboe, Arne, 2009, In : Journal of Neurochemistry. s2, p. 105

    Research output: Contribution to journalConference abstract in journalResearch

  36. Published

    Leaching of estrogenic hormones from manure-treated structured soils

    Kjær, J., Olsen, P., Bach, K., Barlebo, H. C., Ingerslev, F., Hansen, M. & Halling-Sørensen, B., 2007, In : Environmental Science & Technology (Washington). 41, 11, p. 3911-3917

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic canser by FISH

    Kirkegaard, T., Witton, C. J., Edwards, J., Nielsen, K. V., Jensen, L. B., Campbell, F. M., Cooke, T. G. & Bartlett, J. M. S., 2010, In : Histopathology. 2010, 56, p. 203-211

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance

    Kilts, T., Ameye, L., Syed-Picard, F., Ono, M., Berendsen, A. D., Oldberg, A., Heegaard, Anne-Marie, Bi, Y. & Young, M. F., 2009, In : Scandinavian Journal of Medicine & Science in Sports Online. 19, 4, p. 536-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell.

    Khalid, S. A., Friedrichsen, G. M., Christensen, Søren Brøgger, El Tahir, A. & Satti, G. M., 2007, In : ARKIVOC. ix, p. 129-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Sample preparation in membrane introduction mass spectrometry: fundamental extraction techniques

    Ketola, R. A., Kotiaho, T. & Lauritsen, F. R., 2010, Handbook of sample preparation. Pawlizyn, J. & Lord, H. L. (eds.). Hoboken: Wiley, p. 149-162

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  41. Published

    Hyphenated NMR techniques

    Kesting, J. R., Kongstad, Kenneth Thermann & Jaroszewski, J. W., 2011, Biomolecular NMR spectroscopy. Dingley, A. J. & Pascal, S. M. (eds.). Amsterdam: IOS Press, Vol. 3. p. 413-434 (Advances in biomedical spectroscopy, Vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. Published

    Nu kan forfalskede lægemidler afsløres

    Kesting, J. R., Adsersen, A. & Gudiksen, L., Dec 2010, In : Lægemiddelforskning. 2010, p. 4-6

    Research output: Contribution to journalJournal articleCommunication

  43. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In : Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Identification of adulterants in a Chinese herbal medicine by LC-HRMS and LC-MS-SPE/NMR and comparative in vivo study with standards in a hypertensive rat model

    Kesting, J. R., Huang, J. & Sørensen, D., 2010, In : Journal of Pharmaceutical and Biomedical Analysis. 51, 3, p. 705-711

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    HPLC-MS-SPE-NMR and other modern instrumental techniques in analysis af complex natural products mixtures

    Kesting, J. R., 2010, København: Det Farmaceutiske Fakultet. 152 p.

    Research output: Book/ReportPh.D. thesisResearch

  46. Published

    Reduced cerebral blood flow and oxygen consumption in cirrhosis patients with acute hepatic encephalopathy

    Keiding, S., Iversen, P., Sørensen, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Gjedde, A., Schousboe, Arne & Vilstrup, H., 2009, In : Journal of Neurochemistry. s1, p. 269-270

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4

    Kayser, O., Julsing, M. K., Vasilev, N. P., Schneidman-Duhovny, D., Koulman, A., Clarkson, C., Woerdenbag, H. J., Ionkova, I., Wolfson, H. J., Bos, R., Muntendam, R., Jaroszewski, J. W. & Quax, W. J., 2008, In : Planta Medica. 74, 9, p. 925 (SL74)

    Research output: Contribution to journalConference abstract in journalResearch

  48. Published

    Brug biblioteket - find informationen: kompendium i biblioteksvejledning og informationssøgning

    Kastrup, E. H., Kristiansen, D., Kaad, L. & Weile, Martin, 2008, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet.

    Research output: Book/ReportCompendium/lecture notesEducation

  49. Published

    Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4

    Kasper, C., Frydenvang, Karla Andrea, Naur, P., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 2008, In : FEBS Letters. 582, 29, p. 4089-4094

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    On the temperature dependence of complex formation between chitosan and proteins

    Kasimova, M. R., Valázquez-Campoy, A. & Nielsen, Hanne Mørck, 2011, In : Biomacromolecules. 12, 7, p. 2534-2543

    Research output: Contribution to journalJournal articleResearchpeer-review