Research areas

  1. Published

    Nanobodies fra kameler - En ny klasse antistoffer til diagnostik og behandling. / Skottrup, Peter Durand; Clausen, Rasmus Prætorius; Riise, Erik .

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 4-6.

    Research output: Contribution to journalJournal articleCommunication

  2. Published

    Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis. / Skottrup, Peter Durand; Leonard, Paul; Kaczmarek, Jakub; Veillard, Florian; Johannes Enghild, Jan; O'Kennedy, Richard; Sroka, Aneta; Clausen, Rasmus Prætorius; Potempa, Jan; Riise, Erik Skjold.

    In: Analytical Biochemistry, Vol. 415, No. 2, 2011, p. 158-167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Towards on-site pathogen detection using antibody-based sensors. / Skottrup, Peter Durand; Nicolaisen, Mogens; Justesen, Annemarie Fejer.

    In: Biosensors and Bioelectronics, Vol. 24, No. 3, 2008, p. 339-348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Superparamagnetic bead interactions with functionalized surfaces characterized by an immunomicroarray. / Skottrup, Peter Durand; Hansen, Mikkel Fougt; Moresco, Jacob Lange; Deryabina, Maria; Svendsen, Winnie Edith; Jakobsen, Mogens Havsteen; Dufva, Martin.

    In: Acta Biomaterialia, Vol. 6, No. 10, 2010, p. 3936-3946.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Small biomolecular scaffolds for improved biosensor performance. / Skottrup, Peter Durand.

    In: Analytical Biochemistry, Vol. 406, No. 1, 2010, p. 1-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The cysteine protease RgpB as a biomarker for the periodonto-pathogen Porphyromonas gingivalis: Nanobody selection and assay development. / Skottrup, Peter Durand; Leonard, Paul; Kaczmarek, Jakub; Veillard, Florian; Johannes Enghild, Jan; O'Kennedy, Richard; Sroka, Aneta; Clausen, Rasmus Prætorius; Potempa, Jan; Riise, Erik Skjold.

    2011. Poster session presented at Affinity2011, Tavira, Portugal.

    Research output: Contribution to conferencePosterResearch

  7. Published

    Metabolic activation of carboxylic acids. / Skonberg, Christian; Olsen, Jørgen; Madsen, Kim Grimstrup; Hansen, Steen Honore'; Grillo, Mark P.

    In: Expert Opinion on Drug Metabolism & Toxicology, Vol. 4, No. 4, 2008, p. 425-438.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Pitfalls in the sample preparation and analysis of N-acylethanolamines. / Skonberg, Christian; Artmann, Andreas; Cornett, Claus; Hansen, Steen Honore'; Hansen, Harald S.

    In: Journal of Lipid Research, Vol. 51, 2010, p. 3062-3073.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors. / Sivaprakasam, Mangaleswaran; Hansen, Kasper Bø; David, Olivier; Nielsen, Birgitte; Traynelis, Stephen F; Clausen, Rasmus Prætorius; Couty, François; Bunch, Lennart.

    In: ChemMedChem, Vol. 4, No. 1, 2009, p. 110-117.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Direct microcomputer controlled determination of zinc in human serum by flow injection atomic absorption spectrometry. / Simonsen, Kirsten Wiese; Nielsen, Bent; Jensen, Arne; Andersen, Jan Rud.

    In: Journal of Analytical Atomic Spectrometry, Vol. 1, No. 6, 01.01.1986, p. 453-456.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications. / Sikanen, Tiina; Pedersen-Bjergaard, Stig; Jensen, Henrik; Kostiainen, Risto; Rasmussen, Knut Einar; Kotiaho, Tapio.

    In: Analytica Chimica Acta, Vol. 658, 2010, p. 133-140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    In Vitro Reactivity of Carboxylic Acid-CoA Thioesters with Glutathione. / Sidenius, Ulrik; Skonberg, Christian; Olsen, Jørgen; Hansen, Steen Honore'.

    In: Chemical Research in Toxicology, Vol. 17, No. 1, 2004, p. 75-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Metabolic profiles of the brains of Zucker Diabetic Fatty, Zucker Obese and Sprague-Dawley rats and the involvement of glycogen metabolism. / Sickmann, Helle Mark; Bouman, S. D.; Schousboe, Arne; Tracey, W.R.; Waagepetersen, Helle S.

    In: Journal of Neurochemistry, No. s1, 2009, p. 293-293.

    Research output: Contribution to journalConference abstract in journalResearch

  14. Published

    Glutamatergic neurotransmission under physiological and diabetic conditions - involvement of brain glycogen. / Sickmann, Helle Mark.

    København : Det Farmaceutiske Fakultet, 2009. 81 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published

    Functional significance of brain glycogen in sustaining glutamatergic neurotransmission. / Sickmann, Helle M; Walls, Anne B; Schousboe, Arne; Bouman, Stephan D; Waagepetersen, Helle S.

    In: Journal of Neurochemistry, Vol. 109, No. Suppl. 1, 2009, p. 80-86.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis. / Sickmann, Helle M; Waagepetersen, Helle S; Schousboe, Arne; Benie, Andrew J; Bouman, Stephan D.

    In: Journal of Cerebral Blood Flow and Metabolism, Vol. 30, No. 8, 2010, p. 1527-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Characterization of capsaicin induced responses in mice vas deferens : evidence of CGRP uptake. / Sheykhzade, Majid; Gupta, Saurabh; Sørensen, Tinne; Sørensen, Ole Aabling; Koch, Hans; Boonen, Harrie C M; Back, Ole; Fjalland, Bjarne.

    In: European Journal of Pharmacology, Vol. 667, No. 1-3, 2011, p. 375-382.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Library of biphenyl privileged substructures using a safety-catch linker approach. / Severinsen, Rune; Bourne, Gregory T; Tran, Tran T; Ankersen, Michael; Begtrup, Mikael; Smythe, Mark L.

    In: Journal of Combinatorial Chemistry, Vol. 10, No. 4, 2008, p. 557-566.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting : product quality for patient benefit. / Selen, Arzu; Cruanes, Maria T.; Müllertz, Anette; Dicikinsion, Paul A.; Cook, Jack A.; Polli, James E.; Kesisoglou, Felippos; Crison, John; Johnson, Kevin C.; Muirhead, Gordon T.; Schofield, Timothy; Tsong, Yi.

    In: The AAPS Journal, Vol. 12, No. 3, 2010, p. 465-472.

    Research output: Contribution to journalReviewResearch

  20. Published

    Synthesis of bicyclic acidic amino acids conformationally restricted mimetics of Glu or Asp & work towards the enantioselective total synthesis of cardinalin 3. / Sejberg, Jimmy Jens Povlsen.

    København : Det Farmaceutiske Fakultet, 2009. 169 p.

    Research output: Book/ReportPh.D. thesisResearch

  21. Published

    Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras. / Seigan, Gitte Bonke; Vedel, Line; Matthias, Witt,; Jaroszewski, Jerzy W.; Olsen, Christian Adam; Franzyk, Henrik.

    In: Synthesis, Vol. 2008, No. 15, 2008, p. 2381-2390.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Perceived pain communication among Lithuanian cancer patients. / Sciupokas, Arunas ; Liubarskiene, Zita; Samsanaviciene, Jurgita; Jacobsen, Ramune.

    2011. Abstract from 7th Congress of the European Federation of IASP chapters (EFIC), Hamburg, Germany.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  23. Published

    Glial cell biology : neuronal-glial interaction in nutrition and amino-acid-mediated neurotransmission. / Schousboe, Arne; Waagepetersen, Helle S.

    The newborn brain: Neuroscience and clinical applications. ed. / Hugo Lagercrantz; M.A. Hanson; Laura R. Ment; Donald M. Peebles. 2. ed. Cambridge : Cambridge University Press, 2010. p. 121-128.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  24. Published

    GABA: Homeostatic and pharmacological aspects. / Schousboe, Arne; Waagepetersen, Helle Sønderby.

    In: Progress in Brain Research, Vol. 160, 2007, p. 9-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glial modulation of excitability via glutamate and GABA transporters. / Schousboe, Arne; White, H.S.

    Encyclopedia of basic epilepsy research. ed. / Philip A. Schwartzkroin. Vol. 1 Academic Press, 2009. p. 397-401.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  26. Published

    GABA transport inhibitors and seizure protection : the past and future. / Schousboe, Arne; Madsen, Karsten Kirkegaard; White, Steve.

    In: Future Medicinal Chemistry, Vol. 3, No. 2, 2011, p. 183-187.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes. / Schousboe, Arne; Sickmann, Helle Mark; Bak, Lasse Kristoffer; Schousboe, Inger; Bouman, S.D.; Waagepetersen, Helle S.

    In: Journal of Neurochemistry, No. s1, 2010, p. 288-289.

    Research output: Contribution to journalConference abstract in journalResearch

  28. Published

    Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient. / Schousboe, Arne; Sickmann, Helle M; Walls, Anne B; Bak, Lasse K; Waagepetersen, Helle S.

    In: Neurotoxicity Research, Vol. 18, No. 1, 2010, p. 94-9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    GABA Neurotransmission : An overview. / Schousboe, Arne; Waagepetersen, Helle Sønderby.

    Handbook of Neurochemistry and Molecular Neurobiology: Neurotransmitter Systems. ed. / E. Sylvester Vizi. The Netherlands : Springer Publishing Company, 2008. p. 213-226.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  30. Published

    Gamma-aminobutyric acid (GABA). / Schousboe, Arne; Waagepetersen, Helle Sønderby.

    Encyclopedia of neuroscience. ed. / Larry R. Squire. Vol. 4 Academic Press, 2009. p. 511-515.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  31. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate. / Schousboe, Arne; Bak, Lasse Kristoffer; Sickmann, Helle Mark; Sonnewald, Ursula; Waagepetersen, Helle Sønderby.

    In: Neurotoxicity Research, Vol. 12, No. 4, 2007, p. 263-268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Neuron-glia interactions in glutamatergic neurotransmission : roles of oxidative and glycolytic adenosine triphosphate as energy source. / Schousboe, A; Sickmann, H M; Bak, Lasse Kristoffer; Schousboe, I; Jajo, F S; Faek, S A A; Waagepetersen, H S.

    In: Journal of Neuroscience Research, Vol. 89, No. 12, 01.12.2011, p. 1926-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    New discoveries in isotopic labelling of organic molecules & flow chemistry : a useful technique in organic synthesis. / Schou, Søren Christian.

    København : Det Farmaceutiske Fakultet, 2010. 145 p.

    Research output: Book/ReportPh.D. thesisResearch

  34. Published

    Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus. / Schou, Jesper; Kristiansen, Uffe; Stafford, Gary Ivan; van Heerden, Fanie; Jäger, Anna.

    In: Planta Medica, Vol. 76, No. 12, 08.2010, p. 1217.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    Chemometric methods applied to herbal medicinal products : St. Johns wort. / Schmidt, Bonnie.

    København : Det Farmaceutiske Fakultet, 2008. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  36. Published

    Determination of amorphous content in the pharmaceutical process environment. / Savolainen, Marja; Jouppila, Kirsi; Pajamo, Outi; Christiansen, Leena; Strachan, Clare; Karjalainen, Milja; Rantanen, Jukka Tapio.

    In: Journal of Pharmacy and Pharmacology, Vol. 59, No. 2, 2007, p. 161-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Precipitation of a poorly soluble model drug during in vitro lilpolysis : characterization and dissolution of the precipitate. / Sassene, Philip J.; Knopp, Matthias M.; Hesselkilde, Janne Z.; Koradia, Vishal Shamji; Larsen, Anne Tungelund; Rades, Thomas; Müllertz, Anette.

    In: Journal of Pharmaceutical Sciences, Vol. 99, No. 12, 2010, p. 4982-4991.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles. / Sarmento, B.; Ferreira, D. C.; Jørgensen, Lene; Van De Weert, Marco.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 65, No. 1, 2007, p. 10-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Biodegradation of selected emerging organic contaminants in the environment : an overview. / Sarmah, Ajit K.; Halling-Sørensen, Bent.

    Leading-edge environmental biodegradation. ed. / L.E. Pawley. Nova Science Publishers, 2007. p. 53-93.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  40. Published

    Dipeptide derivatives of AZT : Synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity. / Santos, Cledir; Morais, José; Gouveia, Louís; de Clercq, Erik; Pannecouque, Christophe; Nielsen, Carsten Uhd; Steffansen, Bente; Moreira, Rui; Gomes, Paula.

    In: ChemMedChem, Vol. 3, No. 6, 2008, p. 970-978.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Prediction of the receptor conformation for iGluR2 agonist binding : QM/MM docking to an extensive conformational ensemble generated using normal mode analysis. / Sander, Tommy; Liljefors, Tommy; Balle, Thomas.

    In: Journal of Molecular Graphics and Modelling, Vol. 26, No. 8, 2008, p. 1259-1268.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Docking to flexible nicotinic acetylcholine receptors : a validation study using the acetylcholine binding protein. / Sander, Tommy; Bruun, Anne T; Balle, Thomas.

    In: Journal of Molecular Graphics and Modelling, Vol. 29, No. 3, 2010, p. 415-424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    New insights into the GABAA receptor structure and orthosteric ligand binding : Receptor modeling guided by experimental data. / Sander, Tommy; Frølund, Bente Flensborg; Bruun, Anne Techau; Ivanov, Ivaylo; McCammon, James Andrew; Balle, Thomas.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 79, No. 5, 05.2011, p. 1458-1477.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7. / Sagot, Emanuelle; Pickering, Darryl S; Pu, Xiaosui; Umberti, Michelle; Stensbøl, Tine B; Nielsen, Birgitte; Chapelet, Marion; Bolte, Jean; Gefflaut, Thierry; Bunch, Lennart.

    In: Journal of Medicinal Chemistry, Vol. 51, No. 14, 2008, p. 4093-103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Combined MUC1-specific nanobody-tagged PEG-polyethylenimine polyplex targeting and transcriptional targeting of tBid transgene for directed killing of MUC1 over-expressing tumour cells. / Sadeqzadeh, Elham; Rahbarizadeh, Fatemeh; Ahmadvand, Davoud; Rasaee, Mohammad J.; Parhamifar, Ladan; Moghimi, Seyed Moien.

    In: Journal of Controlled Release, Vol. 156, No. 1, 2011, p. 85-91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Design, synthesis, and in vitro pharmacology of new radiolabeled ¿-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity ¿-hydroxybutyric acid binding sites. / Sabbatini, Paola; Wellendorph, Petrine; Høg, Signe; Pedersen, Martin Holst Friborg; Bräuner-Osborne, Hans; Martiny, Lars; Frølund, Bente Flensborg; Clausen, Rasmus Prætorius.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 17, 2010, p. 6506-6510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    MAO-A inhibitory activity of quercetin from Calluna vulgaris Hull. / Saaby, Lasse; Jäger, Anna Katharina; Rasmussen, Hasse Bonde.

    2008. Poster session presented at 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athen, Greece.

    Research output: Contribution to conferencePosterResearch

  48. Published

    Ubiquitous plant compounds disturb cell-based assays. / Saaby, Lasse; Jäger, Anna K.

    In: Journal of Ethnopharmacology, Vol. 137, No. 1, 01.09.2011, p. 942-943.

    Research output: Contribution to journalComment/debateResearchpeer-review

  49. Published

    Evaluation of immunomodulating and anti-inflammatory effects of a herbal remedy based on rose hip powder (Rosa canina L.). / Saaby, Lasse.

    København : Det Farmaceutiske Fakultet, 2011. 130 p.

    Research output: Book/ReportPh.D. thesisResearch

  50. Published

    Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.). / Saaby, Lasse; Jäger, Anna; Moesby, Lise; Hansen, Erik Wind; Christensen, Søren Brøgger.

    In: Planta Medica, Vol. 76, No. 12, 08.2010, p. 1171.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

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