Research areas

  1. Published

    Direct on-line monitoring of methylseleninic acid metabolism in hepatocytes using membrane inlet mass spectrometry. / Bak, Søren Alex; Hansen, Helle Rüsz; Badolo, Lassina; Lauritsen, Frants Roager.

    2011. Poster session presented at DanSAK9, Danish Symposium for Analytical Chemistry, Lyngby, Denmark.

    Research output: Contribution to conferencePosterResearch

  2. Published

    Enzyme kinetic studies of histone demethylases KDM4C and KDM6A : Towards understanding selectivity of inhibitors targeting oncogenic histone demethylases. / Kristensen, Jan B L; Nielsen, Anders L; Jørgensen, Lars; Kristensen, Line Hyltoft; Helgstrand, Charlotte; Juknaite, Lina; Kristensen, Jesper Langgaard; Kastrup, Jette Sandholm; Clausen, Rasmus Prætorius; Olsen, Lars; Gajhede, Michael.

    In: F E B S Letters, Vol. 585, No. 12, 23.06.2011, p. 1951-1956.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bacterial membrane activity of alpha-peptide/beta-peptoid chimeras : influence of amino acid composition and chain length on the activity against different bacterial strains. / Hein-Kristensen, Line; Knapp, Kolja Michael; Franzyk, Henrik; Gram, Lone.

    In: B M C Microbiology, Vol. 11, No. 1, 22.06.2011, p. 144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. / Lehre, A C; Rowley, N M; Zhou, Y; Holmseth, S; Guo, C; Holen, T; Hua, R; Laake, P; Olofsson, A M; Poblete-Naredo, I; Rusakov, D A; Madsen, Karsten Kirkegaard; Clausen, Rasmus Prætorius; Schousboe, Arne; White, H Steve; Danbolt, N C.

    In: Epilepsy Research, Vol. 95, No. 1-2, 01.06.2011, p. 70-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating. / Kristensen, Anders Skov; Jenkins, Meagan A; Banke, Tue G; Schousboe, Arne; Makino, Yuichi; Johnson, Richard C; Huganir, Richard; Traynelis, Stephen F.

    In: Nature Neuroscience, Vol. 14, No. 6, 01.06.2011, p. 727-735.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy. / Leke, Renata; Bak, Lasse Kristoffer; Iversen, Peter; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Portela, Luis V; Schousboe, Arne; Waagepetersen, Helle S.

    In: Journal of Neurochemistry, Vol. 117, No. 5, 01.06.2011, p. 824-32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In silico predictions of hERG channel blockers in drug discovery : from ligand-based and target-based approaches to systems chemical biology. / Taboureau, Olivier; Jørgensen, Flemming Steen.

    In: Combinatorial Chemistry & High Throughput Screening, Vol. 14, No. 5, 06.2011, p. 375-387.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Epitope grafting, re-creating a conformational Bet v 1 antibody epitope on the surface of the homologous apple allergen Mal d 1. / Holm, Jens; Ferreras, Mercedes; Ipsen, Henrik; Würtzen, Peter A; Gajhede, Michael; Larsen, Jørgen N; Lund, Kaare; Spangfort, Michael D.

    In: Journal of Biological Chemistry, Vol. 286, No. 20, 20.05.2011, p. 17569-17578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Expression and beta-glucan binding properties of Scots pine (Pinus sylvestris L.) antimicrobial protein (Sp-AMP). / Sooriyaarachchi, Sanjeewani; Jaber, Emad; Covarrubias, Adrian Suárez; Ubhayasekera, Wimal; Asiegbu, Frederick O; Mowbray, Sherry L.

    In: Plant Molecular Biology, Vol. 77, No. 1-2, 17.05.2011, p. 33-45.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Extraction and detection of Ionophores in the Aquatic Environment. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Björklund, Erland; Halling-Sørensen, Bent.

    2011. Poster session presented at 21th SETAC Europe, Milan, Italy.

    Research output: Contribution to conferencePosterResearch

  11. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors. / Dallanoce, Clelia; Magrone, Pietro; Matera, Carlo; Frigerio, Fabio; Grazioso, Giovanni; De Amici, Marco; Fucile, Sergio; Piccari, Vanessa; Frydenvang, Karla Andrea; Pucci, Luca; Gotti, Cecilia; Clementi, Francesco; De Micheli, Carlo.

    In: ChemMedChem, Vol. 6, No. 5, 02.05.2011, p. 889-903.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases. / Vandecaetsbeek, Ilse; Christensen, Søren Brøgger; Liu, Huizhen; van Veldhoven, Paul P; Waelkens, Etienne; Eggermont, Jan; Raeymaekers, Luc; Møller, Jesper V; Nissen, Poul; Wuytack, Frank; Vangheluwe, Peter.

    In: BBA General Subjects, Vol. 1813, No. 5, 01.05.2011, p. 1118-1127.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    1,2,3-triazoles in peptidomimetic chemistry. / Pedersen, Daniel Sejer; Abell, Andrew.

    In: European Journal of Organic Chemistry, Vol. 2011, No. 13, 05.2011, p. 2399-2411.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    New insights into the GABAA receptor structure and orthosteric ligand binding : Receptor modeling guided by experimental data. / Sander, Tommy; Frølund, Bente Flensborg; Bruun, Anne Techau; Ivanov, Ivaylo; McCammon, James Andrew; Balle, Thomas.

    In: Proteins: Structure, Function, and Bioinformatics, Vol. 79, No. 5, 05.2011, p. 1458-1477.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Studies of monoamine transporters : Phosphorylation of the serotonin transporter and interactions of antidepressants with the serotonin and norepinephrine transporters. / Sørensen, Lena.

    København : Det Farmaceutiske Fakultet, 2011. 174 p.

    Research output: Book/ReportPh.D. thesisResearch

  16. Published

    X-ray crystal structure and small-angle X-ray scattering of sheep liver sorbitol dehydrogenase. / Yennawar, Hemant; Møller, Magda; Gillilan, Richard; Yennawar, Neela.

    In: Acta Crystallographica. Section D: Biological Crystallography, Vol. 67, No. Pt 5, 05.2011, p. 440-446.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers. / Lappin, Graham ; Shishikura, Yoko; Jochemsen, Roeline; Weaver, Richard John ; Gesson, Charlotte; Houston, J. Brian ; Oosterhuis, Berend; Bjerrum, Ole Jannik; Grynkiewicz, Grzegorz; Alder, Jane; Rowland, Malcolm; Garner, Colin.

    In: European Journal of Pharmaceutical Sciences, Vol. 43, No. 3, 20.04.2011, p. 141-150.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pharmacological properties of Anagallis arvensis L. ("scarlet pimpernel") and Anagallis foemina Mill. ("blue pimpernel") traditionally used as wound healing remedies in Navarra (Spain). / López, Víctor; Jäger, Anna Katharina; Akerreta, Silvia; Cavero, Rita Yolanda; Calvo, Maria Isabel.

    In: Journal of Ethnopharmacology, Vol. 134, No. 3, 12.04.2011, p. 1014-1017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Electrophilic organic selenium reagents : protonated seleninic acids as precursors for unsymmetrical aromatic selenides. / Stuhr-Hansen, Nicolai; Sølling, Theis Ivan; Henriksen, Lars.

    In: Tetrahedron, Vol. 67, No. 14, 08.04.2011, p. 2633-2643.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    ZP2307, a novel cyclic PTH(1-17) analog, reversed established osteopenia in adult ovariectomized rats. / Vääräniemi, Jukka; Morko, Jukka ; Peng, ZhiQi; Rissanen, Jukka P ; Suominen, Mari I; Fagerlund, Katja M; Suutari, Tiina A; Boonen, Harrie C.M.; Neerup, Trine SR; Bak, Hanne H ; Halleen, Jussi M .

    2011. Poster session presented at 3rd Joint meeting of the European Calcified Tissue Society and International Bone and Mineral Society, Athens, Greece.

    Research output: Contribution to conferencePosterResearch

  21. Published

    Discovery of benzamide analogues as a novel class of 5-HT3 receptor agonists. / Jørgensen, Charlotte Grube; Frølund, Bente Flensborg; Kehler, Jan; Jensen, Anders Asbjørn.

    In: ChemMedChem, Vol. 6, No. 4, 04.04.2011, p. 725-736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity. / Søvsø Jensen, Bent; Christensen, Søren Brøgger; Jäger, Anna Katharina; Rønsted, Nina Astrid Helene.

    In: Biochemical Systematics and Ecology, Vol. 39, No. 2, 04.2011, p. 153-155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Glutamate receptor agonists : stereochemical aspects. / Vogensen, Stine Byskov; Greenwood, Jeremy R; Bunch, Lennart; Clausen, Rasmus Prætorius.

    In: Current Topics in Medicinal Chemistry, Vol. 11, No. 7, 04.2011, p. 887-906.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. / Bach, Anders*; Eildal, Jonas Nii Nortey*; Stuhr-Hansen, Nicolai; Deeskamp, Rasmus; Gottschalk, Marie; Pedersen, Søren Wittrup; Kristensen, Anders Skov; Strømgaard, Kristian (*Shared 1st authors).

    In: Journal of Medicinal Chemistry, Vol. 54, No. 5, 10.03.2011, p. 1333-1346.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    European new safe and innovative medicines initiatives : history and progress (through December 2009). / Bjerrum, Ole Jannik; H. Linden, Hans.

    Translational medicine and drug discovery. Cambridge : Cambridge University Press, 2011. p. 265-288.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

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