Research areas

  1. Published

    Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions: the effect of lipid composition

    Yaghmur, Anan, Rappolt, M., Østergaard, Jesper, Larsen, C. S. & Larsen, Susan Weng, 2012, In : Langmuir. 28, 5, p. 2881-2889

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression

    Jensen, L. B., Griger, J., Naeye, B., Varkouhi, A. K., Raemdonck, K., Schiffelers, R., Lammers, T., Storm, G., Smedt, S. C. D., Sproat, B. S., Nielsen, Hanne Mørck & Foged, Camilla, 2012, In : Pharmaceutical Research. 29, p. 669-682

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry

    Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In : Journal of Surfactants and Detergents. 15, p. 9-21

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cyclodextrins: efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems

    Stojanov, M., Nielsen, Hanne Mørck & Larsen, K. L., 2012, In : International Journal of Pharmaceutics. 422, 1-2, p. 349-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration

    Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In : Biomacromolecules. 13, p. 905-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA

    Jensen, D. M. K., Jensen, L. B., Koocheki, S., Cun, D., Nielsen, Hanne Mørck, Foged, Camilla & Bengtson, L., 2012, In : Journal of Controlled Release. 157, 1, p. 141-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

    Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In : International Journal of Pharmaceutics. 428, 1-2, p. 171-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Drugs for the neglected disease malaria based on natural products

    Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 2012, Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. Tringali, C. (ed.). 2 ed. Boca Raton: CRC Press, p. 525-550

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection

    Gammelgaard, Bente, Møller, Laura Hyrup, Gabel-Jensen, C. & Steffansen, B., 2012, In : Biological Trace Element Research. 145, 2, p. 248-256

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane exctraction

    Balchen, M., Lund, H., Reubsaet, L. & Pedersen-Bjergaard, Stig, 2012, In : Analytica Chimica Acta. 716, p. 16-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Forced degradation of therapeutic proteins

    Hawe, A., Wiggenhorn, M., van de Weert, Marco, Garbe, J. H. O., Mahler, H. & Jiskoot, W., 2012, In : Journal of Pharmaceutical Sciences. 101, 3, p. 895-913

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

    Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik, 2012, In : Langmuir. 28, 3, p. 1804-1815

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service

    Kaae, Susanne & Nørgaard, Lotte Stig, 2012, In : International Journal of Pharmacy Practice. 20, p. 99-106

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS

    Gammelgaard, Bente, Stürup, Stefan & Christensen, M. V., 2012, In : Metallomics. 4, 2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In : Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journalJournal articleResearch

  17. Published

    In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products

    Devraj, R., Williams, H. D., Warren, D. B., Mullertz, Anette , Porter, C. J. H. & Pouton, C. W., 2012, In : International Journal of Pharmaceutics. 441, 1-2, p. 323-333

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems

    Thomas, N., Mullertz, Anette , Graf, A. & Rades, T., 2012, In : Journal of Pharmaceutical Sciences. 101, 5, p. 1721-1731

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo

    Mullertz, Anette , Fatouros, D. G., Smith, J. R., Vertzoni, M. & Reppas, C., 2012, In : Molecular Pharmaceutics. 9, 2, p. 237-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Interaction of peptidomimetics with bilayer membranes: biophysical characterization and cellular uptake

    Jing, X., Kasimova, M. R., Simonsen, A. H., Jørgensen, Lene, Malmsten, M., Franzyk, Henrik & Foged, Camilla, 2012, In : Langmuir. 28, 11, p. 5167-5175

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression

    Lunøe, K., Martinez-Sierra, J. G., Gammelgaard, Bente & Alonso, J. I. G., 2012, In : Analytical and Bioanalytical Chemistry. 402, 9, p. 2749-2763

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Introduction to pharmaceutical chemical analysis

    Hansen, S. H., Pedersen-Bjergaard, Stig & Rasmussen, K. E., 2012, Chichester: Wiley. 477 p.

    Research output: Book/ReportBookEducationpeer-review

  23. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)

    Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In : Analytical and Bioanalytical Chemistry. 402, p. 2131-2139

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction

    Koradia, V. S., Tenho, M., Diego, H. L. D., Ringkjøbing-Elma, M., Sonnergaard, J., Salonen, J., Lehto, V. & Rantanen, Jukka, 2012, In : Pharmaceutical Research. 29, 1, p. 134-144

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors

    Kristensen, L. H., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 168 p.

    Research output: Book/ReportPh.D. thesisResearch

  26. Published

    License to kill: formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems

    Foged, Camilla, Hansen, J. & Agger, E. M., 2012, In : European Journal of Pharmaceutical Sciences. 45, 4, p. 482-491

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine

    Thunig, J., Flø, L., Pedersen-Bjergaard, Stig, Hansen, S. H. & Janfelt, Christian, 2012, In : Rapid Communications in Massspectrometry. 26, 2, p. 133-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis

    Ye, F., Jensen, Henrik, Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. S. & Østergaard, Jesper, 2012, In : Journal of Pharmaceutical and Biomedical Analysis. 61, p. 176-183

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells

    Yang, L., Fawcett, J. P., Østergaard, Jesper, Zhang, H. & Tucker, I. G., 2012, In : Molecular Pharmaceutics. 9, 1, p. 29-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy)

    Marchi, M., Jørgensen, S. E., Pulselli, F. M., Marchettini, N. & Bastianoni, S., 2012, In : Ecological Modelling. 225, p. 40-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies

    Escudier, B., Osanto, S., Ljungberg, B., Porta, C., Wagstaff, J., Mulders, P., Gore, M., Bex, A., Bellmunt, J., Bracarda, S., Franklin, A., Honoré, P. G. H., Ravaud, A., Stein, J. V., Aziz, Z. & Akaza, H., 2012, In : Cancer Treatment Reviews. 38, 2, p. 127-132 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    NMR spectroscopy for metabolic profiling of plant extracts

    Yilmaz, A., 2012, København: Faculty of Health and Medical Sciences, University of Copenhagen. 114 p.

    Research output: Book/ReportPh.D. thesisResearch

  33. Published

    Polymer-mediated anti-solvent crystallization of nitrendipine: Monodispersed spherical crystals and growth mechanism

    Xia, D., Ouyang, M., Wu, J., Jiang, Y., Piao, H., Sun, S., Zheng, L., Rantanen, Jukka, Cui, F. & Yang, Mingshi, 2012, In : Pharmaceutical Research. 29, p. 158-169

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    RS-Predictor models augmented with SMARTCyp reactivities: robust metabolic regioselectivity predictions for nine CYP isozymes

    Zaretzki, J., Rydberg, P., Bergeron, C., Bennett, K. P., Olsen, L. & Breneman, C. M., 2012, In : Journal of Chemical Information and Modeling. 52, 6, p. 1637-1659

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix

    Ye, F., Larsen, Susan Weng, Yaghmur, Anan, Jensen, H., Larsen, C. S. & Østergaard, Jesper, 2012, In : European Journal of Pharmaceutical Sciences. 46, 1-2, p. 72-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Role of Cu2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides

    Pedersen, J. T., 2012, København: Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet. 85 p.

    Research output: Book/ReportPh.D. thesisResearch

  37. Published

    Role of excipients on solid-state properties of piroxicam during processing

    Christensen, N. P. A., Cornett, Claus & Rantanen, Jukka, 2012, In : Journal of Pharmaceutical Sciences. 101, 3, p. 1202-1211

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Self-assembled nanostructures of fully hydrated monoelaidin - Elaidic and monoelaidin - Oleic acid systems

    Yaghmur, Anan, Satori, B. & Rappolt, M., 2012, In : Langmuir. 28, p. 10105-10119

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation

    Rand, Kasper Dyrberg, Pringle, S. D., Morris, M. & Brown, J. M., 2012, In : Analytical Chemistry. 84, 4, p. 1931-1940

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators

    Kaae, B. H., Harpsøe, Kasper, Kvist, T., Mathiesen, Jesper M., Mølck, C., Gloriam, David E., Jimenez, H. N., Uberti, M. A., Nielsen, S. M., Nielsen, Birgitte, Bräuner-Osborne, Hans, Sauerberg, P., Clausen, Rasmus Prætorius & Madsen, Ulf, 2012, In : ChemMedChem. 7, 3, p. 440-451

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Tool boxes for an integrated ecological and environmental management

    Jørgensen, S. E. & Nielsen, S. N., 2012, In : Ecological Indicators. 21, p. 104-109

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful

    Holm, R., Hesselkilde, J. Z., Jørgensen, E. B. & Mullertz, Anette , 2012, In : European Journal of Pharmaceutical Sciences. 47, p. 347-351

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca

    González, C. R., Björklund, E., Forteza, R. & Cerdà, V., 2012, In : International Journal of Environmental Analytical Chemistry. 92, 12, p. 1-16, iFirst

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Acetylcholine binding protein as model of alpha4beta2 nicotinic acetylcholine receptors: Structural and functional characterization

    Rohde, L. A. H., 19 Dec 2011, København: Det Farmaceutiske Fakultet. 104 p.

    Research output: Book/ReportPh.D. thesisResearch

  45. Published

    3-Hydroxy-2'-methoxy-6-methylflavone: a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes

    Karim, N., Gavande, N., Wellendorph, Petrine, Johnston, G. A. R., Hanrahan, J. R. & Chebib, M., 15 Dec 2011, In : Biochemical Pharmacology. 82, 12, p. 1971-1983

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds

    Heng, S., Tieu, W., Hautmann, S., Kuan, K., Pedersen, D. S., Pietsch, M., Gütschow, M. & Abell, A. D., 15 Dec 2011, In : Bioorganic & Medicinal Chemistry. 19, 24, p. 7453-7463

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Characterization of upper thoracic spinal neurons receiving noxious cardiac and/or somatic inputs in diabetic rats

    Ghorbani, M. L. M., Qin, C., Wu, M., Farber, J. P., Sheykhzade, Majid, Fjalland, B., Nyborg, N. C. B. & Foreman, R. D., 7 Dec 2011, In : Autonomic Neuroscience: Basic and Clinical. 165, 2, p. 168-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Synthesis of the thiazole-thiazoline fragment of largazole analogues

    Diness, Frederik, Nielsen, D. S. & Fairlie, D. P., 2 Dec 2011, In : Journal of Organic Chemistry. 76, 23, p. 9845-9851

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A pinch of sodium

    Müller, M. S., 1 Dec 2011, In : Nature Chemistry. 3, 12, p. 974

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Jajo, F. S., Faek, S. A. A. & Waagepetersen, Helle S., 1 Dec 2011, In : Journal of Neuroscience Research. 89, 12, p. 1926-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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