Research areas

  1. Published

    Characterization of bupivacaine-loaded formulations based on liquid crystalline phases and microemulsions : the effect of lipid composition. / Yaghmur, Anan; Rappolt, Michael; Østergaard, Jesper; Larsen, Claus Selch; Larsen, Susan Weng.

    In: Langmuir, Vol. 28, No. 5, 2012, p. 2881-2889.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Comparison of polymeric siRNA nanocarriers in murine LPS-activated macrophage cell line: Gene silencing, toxicity and off-target gene expression. / Jensen, Linda Boye; Griger, Joscha; Naeye, Broes; Varkouhi, Amir K. ; Raemdonck, Koen; Schiffelers, Raymond; Lammers, Twan; Storm, Gert; Smedt, Stefaan C. de; Sproat, Brian S.; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 669-682.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry. / Lund, Henrik; Kaasgaard, Svend Gunnar; Skagerlind, Peter ; Jørgensen, Lene; Jørgensen, Christian Isak; van de Weert, Marco.

    In: Journal of Surfactants and Detergents, Vol. 15, 2012, p. 9-21.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cyclodextrins : efficient biocompatible solubilizing excipients for bromhexine liquid and semi-solid drug delivery systems. / Stojanov, Mladen; Nielsen, Hanne Mørck; Larsen, Kim Lambertsen.

    In: International Journal of Pharmaceutics, Vol. 422, No. 1-2, 2012, p. 349-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor. / Knudsen, Nina Østergaard; Schiffelers, Raymond M.; Jørgensen, Lene; Hansen, Jens; Frøkjær, Sven; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 428, No. 1-2, 2012, p. 171-177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Design space approach in the optimization of the spray-drying process. / Lebrun, Pierre; Krier, Fabrice; Mantanus, Jérôme ; Grohganz, Holger; Yang, Mingshi; Rozet, Eric; Boulanger, Bruno; Evrard, Brigitte; Rantanen, Jukka; Hubert, Philippe.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 80, No. 1, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Drugs for the neglected disease malaria based on natural products. / Christensen, Søren Brøgger; Bygbjerg, Ib Christian.

    Bioactive compounds from natural sources: natural products as lead compounds in drug discovery. ed. / Corrado Tringali. 2. ed. Boca Raton : CRC Press, 2012. p. 525-550.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Estimating intestinal absorption of inorganic selenium compounds by in vitro flux and biotransformation studies in Caco-2 cells and ICP-MS detection. / Gammelgaard, Bente; Rasmussen, Laura Hyrup; Gabel-Jensen, Charlotte; Steffansen, Bente.

    In: Biological Trace Element Research, Vol. 145, No. 2, 2012, p. 248-256.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Fast, selective, and sensitive analysis of low-abundance peptides in human plasma by electromembrane exctraction. / Balchen, Marte; Lund, Hanne ; Reubsaet, Léon; Pedersen-Bjergaard, Stig.

    In: Analytica Chimica Acta, Vol. 716, 2012, p. 16-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Forced degradation of therapeutic proteins. / Hawe, Andrea; Wiggenhorn, Michael; van de Weert, Marco; Garbe, Joerg H. O.; Mahler, Hanns-Christian; Jiskoot, Wim.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 895-913.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces. / Hartvig, Rune Andersen; van de Weert, Marco; Østergaard, Jesper; Jørgensen, Lene; Jensen, Henrik.

    In: Langmuir, Vol. 28, No. 3, 2012, p. 1804-1815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service. / Kaae, Susanne; Nørgaard, Lotte Stig.

    In: International Journal of Pharmacy Practice, Vol. 20, 2012, p. 99-106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS. / Gammelgaard, Bente; Stürup, Stefan; Christensen, Malene Vinther.

    In: Metallomics, Vol. 4, No. 2, 2012, p. 149-155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Håb om at ramme latente bakterier i deres skjul. / Bahnsen, Jesper Søborg; Water, Jorrit Jeroen; Foged, Camilla; Franzyk, Henrik; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning 2012, Vol. 2012, 2012, p. 12-14.

    Research output: Contribution to journalJournal articleResearch

  17. Published

    In vitro digestion testing of lipid-based delivery systems : calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. / Devraj, Ravi; Williams, Hywel D; Warren, Dallas B; Mullertz, Anette; Porter, Christopher J H; Pouton, Colin W.

    In: International Journal of Pharmaceutics, Vol. 441, No. 1-2, 2012, p. 323-333.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Influence of lipid composition and drug load on the in vitro performance of self-nanoemulsifying drug delivery systems. / Thomas, Nicky; Müllertz, Anette; Graf, Anja; Rades, Thomas.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 5, 2012, p. 1721-1731.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo. / Müllertz, Anette; Fatouros, Dimitrios G.; Smith, James R.; Vertzoni, Maria; Reppas, Christos.

    In: Molecular Pharmaceutics, Vol. 9, No. 2, 2012, p. 237-247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Interaction of peptidomimetics with bilayer membranes : biophysical characterization and cellular uptake. / Jing, Xiaona; Kasimova, Marina Robertovna; Simonsen, Anders H.; Jørgensen, Lene; Malmsten, Martin; Franzyk, Henrik; Foged, Camilla.

    In: Langmuir, Vol. 28, No. 11, 2012, p. 5167-5175.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Internal correction of spectral interferences and mass bias for selenium metabolism studies using enriched stabel isotopes in combination with multiple linear regression. / Lunøe, Kristoffer; Martinez-Sierra, Justo Giner ; Gammelgaard, Bente; Alonso, J. Ignacio Garcia.

    In: Analytical and Bioanalytical Chemistry, Vol. 402, No. 9, 2012, p. 2749-2763.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Introduction to pharmaceutical chemical analysis. / Hansen, Steen Honore'; Pedersen-Bjergaard, Stig; Rasmussen, Knut Einar.

    Chichester : Wiley, 2012. 477 p.

    Research output: Book/ReportBook

  23. Published

    Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS). / Nguyen, Trinh Thi Nhu Tam; Østergaard, Jesper; Stürup, Stefan; Gammelgaard, Bente.

    In: Analytical and Bioanalytical Chemistry, Vol. 402, 2012, p. 2131-2139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Investigation of solid phase composition on tablet surfaces by grazing incidence X-ray diffraction. / Koradia, Vishal Shamji; Tenho, Mikko; Diego, Heidi Lopez de; Ringkjøbing-Elma, Michiel ; Sonnergaard, Jørn; Salonen, Jamo; Lehto, Vesa-Pekka; Rantanen, Jukka.

    In: Pharmaceutical Research, Vol. 29, No. 1, 2012, p. 134-144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Kinetic and structural analyses of Jumonji C histone demethylases for identification of new inhibitors. / Kristensen, Line Hyltoft.

    København : Faculty of Health and Medical Sciences, University of Copenhagen, 2012. 168 p.

    Research output: Book/ReportPh.D. thesis

  26. Published

    License to kill : formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. / Foged, Camilla; Hansen, Jon; Agger, Else Marie.

    In: European Journal of Pharmaceutical Sciences, Vol. 45, No. 4, 2012, p. 482-491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine. / Thunig, Janina; Flø, Linda; Pedersen-Bjergaard, Stig; Hansen, Steen Honore'; Janfelt, Christian.

    In: Rapid Communications in Massspectrometry, Vol. 26, No. 2, 2012, p. 133-140.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Measurement of drug diffusivities in pharmaceutical solvents using Taylor dispersion analysis. / Ye, Fengbin; Jensen, Henrik; Larsen, Susan Weng; Yaghmur, Anan; Larsen, Claus Selch; Østergaard, Jesper.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 61, 2012, p. 176-183.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells. / Yang, Lin; Fawcett, J. Paul; Østergaard, Jesper; Zhang, Hu; Tucker, Ian G.

    In: Molecular Pharmaceutics, Vol. 9, No. 1, 2012, p. 29-36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Modelling the carbon cycle of Siena province (Tuscany, central Italy). / Marchi, Michela; Jørgensen, Sven Erik; Pulselli, Federico Maria; Marchettini, Nadia; Bastianoni, Simone.

    In: Ecological Modelling, Vol. 225, 2012, p. 40-60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Multidisciplinary management of metastatic renal cell carcinoma in the era of targeted therapies. / Escudier, B; Osanto, S; Ljungberg, B; Porta, C; Wagstaff, John; Mulders, Peter; Gore, Martin; Bex, A; Bellmunt, Jaquim; Bracarda, Sergio; Franklin, Alex; Honoré, Per Gustaf Hartvig; Ravaud, Alain; Stein, Jeanne van; Aziz, Zeb ; Akaza, Hideyuki .

    In: Cancer Treatment Reviews, Vol. 38, No. 2, 2012, p. 127-132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    NMR spectroscopy for metabolic profiling of plant extracts. / Yilmaz, Ali.

    København : Faculty of Health and Medical Sciences, University of Copenhagen, 2012. 114 p.

    Research output: Book/ReportPh.D. thesis

  33. Published

    Polymer-mediated anti-solvent crystallization of nitrendipine: Monodispersed spherical crystals and growth mechanism. / Xia, Dengning; Ouyang, Mei; Wu, Jian-Xiong; Jiang, Yanbo; Piao, Hongyu; Sun, Shaoping; Zheng, Li; Rantanen, Jukka; Cui, Fude; Yang, Mingshi.

    In: Pharmaceutical Research, Vol. 29, 2012, p. 158-169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    RS-Predictor models augmented with SMARTCyp reactivities : robust metabolic regioselectivity predictions for nine CYP isozymes. / Zaretzki, Jed; Rydberg, Patrik; Bergeron, Charles; Bennett, Kristin P; Olsen, Lars; Breneman, Curt Mark.

    In: Journal of Chemical Information and Modeling, Vol. 52, No. 6, 2012, p. 1637-1659.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Real-time UV imaging of piroxicam diffusion and distribution from oil solutions into gels mimicking the subcutaneous matrix. / Ye, Fengbin; Larsen, Susan Weng; Yaghmur, Anan; Jensen, Henrik; Larsen, Claus Selch; Østergaard, Jesper.

    In: European Journal of Pharmaceutical Sciences, Vol. 46, No. 1-2, 2012, p. 72-78.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Role of Cu2+ in oligomerization and aggregation of alzheimer's amyloid-β peptides. / Pedersen, Jeppe Trudslev.

    København : Det Farmaceutiske Fakultetsbibliotek, Det Farmaceutiske Fakultet, Københavns Universitet, 2012. 85 p.

    Research output: Book/ReportPh.D. thesis

  37. Published

    Role of excipients on solid-state properties of piroxicam during processing. / Christensen, Niels Peter Aae; Cornett, Claus; Rantanen, Jukka.

    In: Journal of Pharmaceutical Sciences, Vol. 101, No. 3, 2012, p. 1202-1211.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Self-assembled nanostructures of fully hydrated monoelaidin - Elaidic and monoelaidin - Oleic acid systems. / Yaghmur, Anan; Satori, Barbara; Rappolt, Michael.

    In: Langmuir, Vol. 28, 2012, p. 10105-10119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Site-specific analysis of gas-phase hydrogen/deuterium exchange of peptides and proteins by electron transfer dessociation. / Rand, Kasper Dyrberg; Pringle, Steven D.; Morris, Michael; Brown, Jeffery M.

    In: Analytical Chemistry, Vol. 84, No. 4, 2012, p. 1931-1940.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structure-activity relationships for negative allosteric mGluR5 modulators. / Kaae, Birgitte H; Harpsøe, Kasper; Kvist, Trine; Mathiesen, Jesper M; Mølck, Christina; Gloriam, David E; Jimenez, Hermogenes N; Uberti, Michelle A; Nielsen, Søren M; Nielsen, Birgitte; Bräuner-Osborne, Hans; Sauerberg, Per; Clausen, Rasmus Prætorius; Madsen, Ulf.

    In: ChemMedChem, Vol. 7, No. 3, 2012, p. 440-451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Tool boxes for an integrated ecological and environmental management. / Jørgensen, Sven Erik; Nielsen, Søren Nors.

    In: Ecological Indicators, Vol. 21, 2012, p. 104-109.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful. / Holm, Rene; Hesselkilde, Janne Z.; Jørgensen, Erling B.; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 47, 2012, p. 347-351.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Volatile organic compounds in landfill ordorant emissions on the island of Mallorca. / González, Carlos Rodriguez-Navas; Björklund, Erland; Forteza, Rafael; Cerdà, Victor.

    In: International Journal of Environmental Analytical Chemistry, Vol. 92, No. 12, 2012, p. 1-16, iFirst.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Acetylcholine binding protein as model of alpha4beta2 nicotinic acetylcholine receptors : Structural and functional characterization. / Rohde, Line Aagot Hede.

    København : Det Farmaceutiske Fakultet, 2011. 104 p.

    Research output: Book/ReportPh.D. thesis

  45. Published

    3-Hydroxy-2'-methoxy-6-methylflavone : a potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes. / Karim, Nasiara; Gavande, Navnath; Wellendorph, Petrine; Johnston, Graham A R; Hanrahan, Jane R; Chebib, Mary.

    In: Biochemical Pharmacology, Vol. 82, No. 12, 15.12.2011, p. 1971-1983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds. / Heng, Sabrina; Tieu, William; Hautmann, Stephanie; Kuan, Kevin; Pedersen, Daniel Sejer; Pietsch, Markus; Gütschow, Michael; Abell, Andrew D.

    In: Bioorganic & Medicinal Chemistry, Vol. 19, No. 24, 15.12.2011, p. 7453-7463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Characterization of upper thoracic spinal neurons receiving noxious cardiac and/or somatic inputs in diabetic rats. / Ghorbani, Marie Louise M; Qin, Chao; Wu, Mingyuan; Farber, Jay P; Sheykhzade, Majid; Fjalland, Bjarne; Nyborg, Niels C B; Foreman, Robert D.

    In: Autonomic Neuroscience: Basic and Clinical, Vol. 165, No. 2, 07.12.2011, p. 168-177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Synthesis of the thiazole-thiazoline fragment of largazole analogues. / Diness, Frederik; Nielsen, Daniel Skovhaur; Fairlie, David P.

    In: Journal of Organic Chemistry, Vol. 76, No. 23, 02.12.2011, p. 9845-9851.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    A pinch of sodium. / Müller, Margit Silke.

    In: Nature Chemistry, Vol. 3, No. 12, 01.12.2011, p. 974.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Neuron-glia interactions in glutamatergic neurotransmission : roles of oxidative and glycolytic adenosine triphosphate as energy source. / Schousboe, A; Sickmann, H M; Bak, Lasse Kristoffer; Schousboe, I; Jajo, F S; Faek, S A A; Waagepetersen, H S.

    In: Journal of Neuroscience Research, Vol. 89, No. 12, 01.12.2011, p. 1926-34.

    Research output: Contribution to journalJournal articleResearchpeer-review

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