Research areas

  1. Published

    An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes

    Crielaard, B. J., Yousefi, A., Schillemans, J. P., Vermehren, C., Buyens, K., Braeckmans, K., Lammers, T. & Storm, G., Dec 2011, In : Journal of Controlled Release. 156, 3, p. 307-314

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published
  3. Published

    Computeren forudsiger lægemidlers omdannelse i leveren

    Rydberg, P. & Olsen, L., Dec 2011, In : Lægemiddelforskning. 2011, p. 44-46

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Funktionelle fibriller som depotmedicin mod prostatakræft

    Jensen, M. G., van Maarschalkerweerd, A. & Gottschalk, T., Dec 2011, In : Lægemiddelforskning. 2011, p. 20-22

    Research output: Contribution to journalJournal articleCommunication

  5. Published

    Gendannelse af ødelagt væv med stamceller

    Møller, E. H., Wen, Y. & Nielsen, Hanne Mørck, Dec 2011, In : Lægemiddelforskning. 2011, p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  6. Published

    Genetisk nanomedicin til behandling af leddegigt

    Foged, Camilla, Jensen, L. B. & Nielsen, Hanne Mørck, Dec 2011, In : Lægemiddelforskning. p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  7. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv

    Janfelt, Christian, Thunig, J., Li, B., Andersen, N. W., Hansen, Harald S. & Hansen, S. H., Dec 2011, In : Lægemiddelforskning. 2011, p. 10-12

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder

    Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In : Lægemiddelforskning. 2011, p. 23-25

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Målrettet fisketur i hjernen giver ny viden om Fantasys virkningssted

    Villumsen, I. S., Vogensen, S. B., Frølund, Bente, Clausen, Rasmus Prætorius & Wellendorph, Petrine, Dec 2011, In : Lægemiddelforskning. 2011, p. 26-28

    Research output: Contribution to journalJournal articleCommunication

  10. Published

    Nanobodies fra kameler - En ny klasse antistoffer til diagnostik og behandling

    Skottrup, P. D., Clausen, Rasmus Prætorius & Riise, E., Dec 2011, In : Lægemiddelforskning. 2011, p. 4-6

    Research output: Contribution to journalJournal articleCommunication

  11. Published

    From retrospective assessment to prospective decisions in natural product isolation: HPLC-SPE-NMR analysis of Carthamus oxyacantha

    Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N. T. & Jaroszewski, J. W., 28 Nov 2011, In : Journal of Natural Products. 74, 11, p. 2454-2461

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Small molecules from spiders used as chemical probes

    Olsen, C. A., Kristensen, Anders Skov & Strømgaard, Kristian, 25 Nov 2011, In : Angewandte Chemie International Edition. 50, 48, p. 11296-11311

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    Gloriam, David E., Wellendorph, Petrine, Johansen, L. D., Thomsen, A. R. B., Phonekeo, K., Pedersen, D. S. & Bräuner-Osborne, Hans, 23 Nov 2011, In : Chemistry & Biology. 18, 11, p. 1489-1498

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Amino triazolo diazepines (Ata) as constrained histidine mimics

    Buysse, K., Farard, J., Nikolaou, A., Vanderheyden, P., Vauquelin, G., Pedersen, D. S., Tourwé, D. & Ballet, S., 16 Nov 2011, In : Organic Letters. 13, 24, p. 6468-6471

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published

    Scientific social responsibility: a call to arms

    Krogsgaard-Larsen, Povl, Thostrup, P. & Besenbacher, F., 11 Nov 2011, In : Angewandte Chemie International Edition. 50, 46, p. 10738-10740

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2

    Mikkelsen, L., Sheykhzade, Majid, Jensen, K. A., Saber, A. T., Jacobsen, N. R., Vogel, U. B., Wallin, H., Loft, Steffen & Møller, Peter, 10 Nov 2011, In : Particle and Fibre Toxicology. 8, 1, p. 32

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., Nov 2011.

    Research output: Contribution to conferencePosterCommunication

  18. Published

    Pharmacological and physiological studies of the calcium-sensing receptor

    Thomsen, A. R. B., Nov 2011, København: Det Farmaceutiske Fakultet. 89 p.

    Research output: Book/ReportPh.D. thesisResearch

  19. Published

    SDF2XYZ2SDF: how to exploit TINKER power in cheminformatics projects

    Tosco, P., Balle, T. & Shiri, F., Nov 2011, In : Journal of Molecular Modeling. 17, 11, p. 3021-3023

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Antimicrobial evaluation of Huilliche plant medicine used to treat wounds

    Mølgaard, Per, Holler, J. G., Asar, B., Liberna, I., Rosenbæk, L. B., Jebjerg, C. P., Jørgensen, L., Lauritzen, J., Guzman, A., Adsersen, A. & Simonsen, H. T., 31 Oct 2011, In : Journal of Ethnopharmacology. 138, 1, p. 219-227

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure: Synthesis, resolution, pharmacology, and crystal structure

    Szymanska, E., Frydenvang, Karla Andrea, Contreras-Sanz, A., Pickering, Darryl S, Frola, E., Serafimoska, Z., Nielsen, Birgitte, Kastrup, Jette Sandholm Jensen & Johansen, Tommy Nørskov, 4 Oct 2011, In : Journal of Medicinal Chemistry. 54, 20, p. 7289-7298

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Antifungal metabolites from fungal endophytes of Pinus strobus

    Sumarah, M. W., Kesting, J. R., Sørensen, D. & Miller, J. D., 1 Oct 2011, In : Phytochemistry. 72, 14-15, p. 1833-1837

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Stress and medicine use for headache: does sense of coherence modify the association?

    Koushede, V. J., Holstein, B. E., Andersen, A. & Hansen, Ebba Holme, 1 Oct 2011, In : European Journal of Public Health. 21, 5, p. 656-61 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump

    Mahmmoud, Y. A. & Christensen, Søren Brøgger, Oct 2011, In : BBA General Subjects. 1808, 10, p. 2413-2420

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The calcium-sensing receptor and calcimimetics in blood pressure modulation

    Smajilovic, S., Yano, S., Jabbari, R. & Tfelt-Hansen, J., Oct 2011, In : British Journal of Pharmacology. 164, 3, p. 884-893

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis

    Yilmaz, A., Nyberg, N. T. & Jaroszewski, J. W., 27 Sep 2011, In : Analytical Chemistry. 83, 21, p. 8278-8285

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study

    Kesting, J. R., Olsen, L., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 26 Sep 2011, In : Journal of Natural Products. 74, 10, p. 2206-2215

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2

    Nielsen, S. D., Fulco, M., Serpi, M., Nielsen, Birgitte, Hansen, M. B., Hansen, K. L., Thomsen, C., Brodbeck, R., Bräuner-Osborne, Hans, Pellicciari, R., Norrby, P., Greenwood, J. R. & Clausen, Rasmus Prætorius, 23 Sep 2011, In : MedChemComm. 2, 11, p. 1120-1124

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats

    Stefkov, G., Kulevanova, S., Miova, B., Dinevska-Kjovkarovska, S., Mølgaard, Per, Jäger, A. K. & Josefsen, K., 1 Sep 2011, In : Pharmaceutical Biology. 49, 9, p. 885-892

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

    Dadsetan, S., Bak, Lasse Kristoffer, Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Leke, R., Schousboe, Arne & Waagepetersen, Helle S., 1 Sep 2011, In : Neurochemistry International. 59, 4, p. 482-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Ubiquitous plant compounds disturb cell-based assays

    Saaby, L. & Jäger, A. K., 1 Sep 2011, In : Journal of Ethnopharmacology. 137, 1, p. 942-943

    Research output: Contribution to journalComment/debateResearchpeer-review

  33. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model

    Rasmussen, Rune Skovgaard, Overgaard, K., Kristiansen, Uffe & Johansen, Flemming Fryd, Sep 2011, In : Neurological Research. 33, 7, p. 774-782 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Do two different reaction mechanisms contribute to the hydroxylation of primary amines by cytochrome P450?

    Rydberg, P. & Olsen, L., Sep 2011, In : Journal of Chemical Theory and Computation. 7, 10, p. 3399-3404

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Evolution and applications of plant pathway resources and databases

    Sucaet, Y. & Deva, T., Sep 2011, In : Briefings in Bioinformatics. 12, 5, p. 530-544

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In : Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In : American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression: comparison with sertraline

    Andreasen T., Jesper, Henningsen, K., Bate, S., Christiansen, S. & Wiborg, O., 1 Aug 2011, In : Journal of Psychopharmacology. 25, 8, p. 1134-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In : Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Extraction and detection of Ionophores in the Aquatic Environment

    Bak, S. A., Hansen, M., Krogh, K. A., Björklund, E. & Halling-Sørensen, B., Aug 2011.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  41. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging

    Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, Henrik, Aug 2011, In : Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1

    Thorn, K., Nielsen, C. U., Jakobsen, P., Steffansen, B., Zercher, C. K. & Begtrup, M., Aug 2011, In : Bioorganic & Medicinal Chemistry Letters. 21, 15, p. 4597-4601

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Open3DALIGN: an open-source software aimed at unsupervised ligand alignment

    Tosco, P., Balle, T. & Shiri, F., 27 Jul 2011, In : Journal of Computer - Aided Molecular Design. 25, 8, p. 777-783

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors

    Harpsøe, Kasper, Ahring, P. K., Christensen, J. K., Jensen, M. L., Peters, D. & Balle, T., 27 Jul 2011, In : Journal of Neuroscience. 31, 30, p. 10759-10766

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    RS-predictor: a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4

    Zaretzki, J., Bergeron, C., Rydberg, P., Huang, T., Bennett, K. P. & Breneman, C. M., 25 Jul 2011, In : Journal of Chemical Information and Modeling. 51, 7, p. 1667-1689

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In : Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Dorvil, Linda Grønborg, Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol

    Madsen, K. K., Ebert, B., Clausen, Rasmus Prætorius, Krogsgaard-Larsen, Povl, Schousboe, Arne & White, H. S., 1 Jul 2011, In : Journal of Pharmacology and Experimental Therapeutics. 338, 1, p. 214-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Temocene: the porphycene analogue of temoporfin (Foscan®)

    Garcia-Diaz, M., Sanchez-Garcia, D., Nonell, S., Soriano, J., Villanueva, A., Stockert, J. C., Canete, M., Sagrista, M. L. & Mora, M., 1 Jul 2011, In : MedChemComm. 2, 7, p. 616-619 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Chemical composition and biological screening of Capsella bursa-pastoris

    Grosso, C., Vinholes, J., Silva, L. R., Guedes de Pinho, P., Goncalves, R. F., Valentao, P., Jäger, A. K. & Andrade, P. B., Jul 2011, In : Revista Brasileira de Farmacognosia. 21, 4, p. 635-644

    Research output: Contribution to journalJournal articleResearchpeer-review

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