Research areas

  1. Published

    An in vitro assay based on surface plasmon resonance to predict the in vivo circulation kinetics of liposomes. / Crielaard, B. J.; Yousefi, A.; Schillemans, J. P.; Vermehren, C.; Buyens, K.; Braeckmans, K.; Lammers, T.; Storm, G.

    In: Journal of Controlled Release, Vol. 156, No. 3, 12.2011, p. 307-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate. / Venskutonyte, Raminta; Frydenvang, Karla; Gajhede, Michael; Bunch, Lennart; Pickering, Darryl S; Kastrup, Jette Sandholm.

    In: Journal of Structural Biology, Vol. 176, No. 3, 12.2011, p. 307-314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Computeren forudsiger lægemidlers omdannelse i leveren. / Rydberg, Patrik; Olsen, Lars.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 44-46.

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Funktionelle fibriller som depotmedicin mod prostatakræft. / Jensen, Minna Grønning; van Maarschalkerweerd, Andreas; Gottschalk, Tine.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 20-22.

    Research output: Contribution to journalJournal articleCommunication

  5. Published

    Gendannelse af ødelagt væv med stamceller. / Møller, Eva Horn; Wen, Yanhong; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  6. Published

    Genetisk nanomedicin til behandling af leddegigt. / Foged, Camilla; Jensen, Linda Boye; Nielsen, Hanne Mørck.

    In: Lægemiddelforskning, 12.2011, p. 7-9.

    Research output: Contribution to journalJournal articleCommunication

  7. Published

    Massespektrometri viser fordelingen af lægemiddelstoffer i planter og væv. / Janfelt, Christian; Thunig, Janina; Li, Bin; Andersen, Niels Wellner; Hansen, Harald S.; Hansen, Steen Honore'.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 10-12.

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    Medicinalplanter og abort : ny viden kan hjælpe afrikanske kvinder. / Jäger, Anna; Kristiansen, Uffe; Rasch, Vibeke.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 23-25.

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Målrettet fisketur i hjernen giver ny viden om Fantasys virkningssted. / Villumsen, Inge Stengaard; Vogensen, Stine Byskov; Frølund, Bente; Clausen, Rasmus Prætorius; Wellendorph, Petrine.

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 26-28.

    Research output: Contribution to journalJournal articleCommunication

  10. Published

    Nanobodies fra kameler - En ny klasse antistoffer til diagnostik og behandling. / Skottrup, Peter Durand; Clausen, Rasmus Prætorius; Riise, Erik .

    In: Lægemiddelforskning, Vol. 2011, 12.2011, p. 4-6.

    Research output: Contribution to journalJournal articleCommunication

  11. Published

    From retrospective assessment to prospective decisions in natural product isolation : HPLC-SPE-NMR analysis of Carthamus oxyacantha. / Johansen, Kenneth T; Wubshet, Sileshi G; Nyberg, Nils T; Jaroszewski, Jerzy W.

    In: Journal of Natural Products, Vol. 74, No. 11, 28.11.2011, p. 2454-2461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Small molecules from spiders used as chemical probes. / Olsen, Christian Adam; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Angewandte Chemie International Edition, Vol. 50, No. 48, 25.11.2011, p. 11296-11311.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor. / Gloriam, David E.; Wellendorph, Petrine; Johansen, Lars Dan; Thomsen, Alex Rojas Bie; Phonekeo, Karina; Pedersen, Daniel Sejer; Bräuner-Osborne, Hans.

    In: Chemistry & Biology, Vol. 18, No. 11, 23.11.2011, p. 1489-1498.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Amino triazolo diazepines (Ata) as constrained histidine mimics. / Buysse, Koen; Farard, Julien; Nikolaou, Alexandros; Vanderheyden, Patrick; Vauquelin, Georges; Pedersen, Daniel Sejer; Tourwé, Dirk; Ballet, Steven .

    In: Organic Letters, Vol. 13, No. 24, 16.11.2011, p. 6468-6471.

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published

    Scientific social responsibility : a call to arms. / Krogsgaard-Larsen, Povl; Thostrup, Peter; Besenbacher, Flemming.

    In: Angewandte Chemie International Edition, Vol. 50, No. 46, 11.11.2011, p. 10738-10740.

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2. / Mikkelsen, Lone; Sheykhzade, Majid; Jensen, Keld A; Saber, Anne T; Jacobsen, Nicklas R.; Vogel, Ulla Birgitte; Wallin, Håkan; Loft, Steffen; Møller, Peter.

    In: Particle and Fibre Toxicology, Vol. 8, No. 1, 10.11.2011, p. 32.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Alleviation of nociception in rats by treatment with ceftriaxone, a ß-lactam that promote the expression of the excitatory amino acid transporter 2. / Bjerrum, Ole Jannik; Abrahamsen, Bjarke; Honoré, Per Gustaf Hartvig.

    2011. Poster session presented at Share Symposium 2010, Copenhagen, Denmark.

    Research output: Contribution to conferencePosterCommunication

  18. Published

    Pharmacological and physiological studies of the calcium-sensing receptor. / Thomsen, Alex Rojas Bie.

    København : Det Farmaceutiske Fakultet, 2011. 89 p.

    Research output: Book/ReportPh.D. thesis

  19. Published

    SDF2XYZ2SDF : how to exploit TINKER power in cheminformatics projects. / Tosco, Paolo; Balle, Thomas; Shiri, Fereshteh.

    In: Journal of Molecular Modeling, Vol. 17, No. 11, 11.2011, p. 3021-3023.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Antimicrobial evaluation of Huilliche plant medicine used to treat wounds. / Mølgaard, Per; Holler, Jes Gitz; Asar, Betül; Liberna, Iwona; Rosenbæk, Lise Bakkestrøm; Jebjerg, Christina Ploug; Jørgensen, Lene; Lauritzen, Jeanette ; Guzman, Alfonso; Adsersen, Anne; Simonsen, Henrik Toft.

    In: Journal of Ethnopharmacology, Vol. 138, No. 1, 31.10.2011, p. 219-227.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A new phenylalanine derivative acts as an antagonist at the AMPA receptor GluA2 and introduces partial domain closure : Synthesis, resolution, pharmacology, and crystal structure. / Szymanska, Ewa; Frydenvang, Karla; Contreras-Sanz, Alberto; Pickering, Darryl S; Frola, Elena; Serafimoska, Zorica; Nielsen, Birgitte; Kastrup, Jette Sandholm; Johansen, Tommy Nørskov.

    In: Journal of Medicinal Chemistry, Vol. 54, No. 20, 04.10.2011, p. 7289-7298.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Antifungal metabolites from fungal endophytes of Pinus strobus. / Sumarah, Mark W; Kesting, Julie R; Sørensen, Dan; Miller, J David.

    In: Phytochemistry, Vol. 72, No. 14-15, 01.10.2011, p. 1833-1837.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Stress and medicine use for headache: does sense of coherence modify the association? / Koushede, Vibeke Jenny; Holstein, Bjørn E; Andersen, Anette; Hansen, Ebba Holme.

    In: European Journal of Public Health, Vol. 21, No. 5, 01.10.2011, p. 656-61.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump. / Mahmmoud, Yasser Ahmed; Christensen, Søren Brøgger.

    In: BBA General Subjects, Vol. 1808, No. 10, 10.2011, p. 2413-2420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The calcium-sensing receptor and calcimimetics in blood pressure modulation. / Smajilovic, Sanela; Yano, Shozo; Jabbari, Reza; Tfelt-Hansen, Jacob.

    In: British Journal of Pharmacology, Vol. 164, No. 3, 10.2011, p. 884-893.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis. / Yilmaz, Ali; Nyberg, Nils T; Jaroszewski, Jerzy W.

    In: Analytical Chemistry, Vol. 83, No. 21, 27.09.2011, p. 8278-8285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures : HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study. / Kesting, Julie Regitze; Olsen, Lars; Stærk, Dan; Tejesvi, Mysore V; Kini, Kukkundoor R; Prakash, Harishchandra S; Jaroszewski, Jerzy W.

    In: Journal of Natural Products, Vol. 74, No. 10, 26.09.2011, p. 2206-2215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2. / Nielsen, Simon Dalsgaard; Fulco, Marica; Serpi, Michaela; Nielsen, Birgitte; Hansen, Maria Brinck ; Hansen, Kasper Lind; Thomsen, Christian; Brodbeck, Robb; Bräuner-Osborne, Hans; Pellicciari, Roberto; Norrby, Per-Ola; Greenwood, Jeremy R; Clausen, Rasmus Prætorius.

    In: MedChemComm, Vol. 2, No. 11, 23.09.2011, p. 1120-1124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors. / Lohse, Brian; Nielsen, Anders L; Kristensen, Jan B L; Helgstrand, Charlotte; Cloos, Paul Andreas Compare; Olsen, Lars; Gajhede, Michael; Clausen, Rasmus Prætorius; Kristensen, Jesper Langgaard.

    In: Angewandte Chemie International Edition, Vol. 50, No. 39, 19.09.2011, p. 9100-9103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. / Stefkov, Gjoshe; Kulevanova, Svetlana; Miova, Biljana; Dinevska-Kjovkarovska, Suzana; Mølgaard, Per; Jäger, Anna K; Josefsen, Knud.

    In: Pharmaceutical Biology, Vol. 49, No. 9, 01.09.2011, p. 885-892.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons. / Dadsetan, Sherry; Bak, Lasse Kristoffer; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Leke, Renata; Schousboe, Arne; Waagepetersen, Helle S.

    In: Neurochemistry International, Vol. 59, No. 4, 01.09.2011, p. 482-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Ubiquitous plant compounds disturb cell-based assays. / Saaby, Lasse; Jäger, Anna K.

    In: Journal of Ethnopharmacology, Vol. 137, No. 1, 01.09.2011, p. 942-943.

    Research output: Contribution to journalComment/debateResearchpeer-review

  33. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model. / Rasmussen, Rune Skovgaard; Overgaard, Karsten; Kristiansen, Uffe; Johansen, Flemming Fryd.

    In: Neurological Research, Vol. 33, No. 7, 09.2011, p. 774-782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Do two different reaction mechanisms contribute to the hydroxylation of primary amines by cytochrome P450? / Rydberg, Patrik; Olsen, Lars.

    In: Journal of Chemical Theory and Computation, Vol. 7, No. 10, 09.2011, p. 3399-3404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Evolution and applications of plant pathway resources and databases. / Sucaet, Yves; Deva, Taru.

    In: Briefings in Bioinformatics, Vol. 12, No. 5, 09.2011, p. 530-544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice. / Richner, Mette; Bjerrum, Ole Jannik; Nykjær, Anders; Vaegter, Christian B.

    In: Journal of Visualized Experiments, No. 54, 18.08.2011, p. e3092.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects. / Dam, Gitte; Keiding, Susanne; Munk, Ole Lajord; Ott, Peter; Buhl, Mads; Vilstrup, Hendrik; Bak, Lasse Kristoffer; Waagepetersen, Helle Sønderby; Schousboe, Arne; Møller, Niels; Sørensen, Michael.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 301, No. 2, 01.08.2011, p. G269-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression : comparison with sertraline. / Andreasen T., Jesper; Henningsen, Kim; Bate, Simon; Christiansen, Sofie; Wiborg, Ove.

    In: Journal of Psychopharmacology, Vol. 25, No. 8, 01.08.2011, p. 1134-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. / Lund, Trine Meldgaard; Obel, Linea F; Risa, Øystein; Sonnewald, Ursula.

    In: Neurochemistry International, Vol. 59, No. 2, 01.08.2011, p. 309-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Extraction and detection of Ionophores in the Aquatic Environment. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Björklund, Erland; Halling-Sørensen, Bent.

    2011. Abstract from 3rd EmCon 2011: International conference on analysis of emerging contaminants in the environment, Copenhagen, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  41. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging. / Ostergaard, Jesper; Ye, Fengbin; Rantanen, Jukka; Yaghmur, Anan; Larsen, Susan Weng; Larsen, Claus Selch; Jensen, Henrik.

    In: Journal of Pharmaceutical Sciences, Vol. 100, No. 8, 08.2011, p. 3405-3410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1. / Thorn, Karina; Nielsen, Carsten Uhd; Jakobsen, Palle; Steffansen, Bente; Zercher, Charles K; Begtrup, Mikael.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 21, No. 15, 08.2011, p. 4597-4601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Open3DALIGN : an open-source software aimed at unsupervised ligand alignment. / Tosco, Paolo; Balle, Thomas; Shiri, Fereshteh.

    In: Journal of Computer - Aided Molecular Design, Vol. 25, No. 8, 27.07.2011, p. 777-783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors. / Harpsøe, Kasper; Ahring, Philip K; Christensen, Jeppe K; Jensen, Marianne L; Peters, Dan; Balle, Thomas.

    In: Journal of Neuroscience, Vol. 31, No. 30, 27.07.2011, p. 10759-10766.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    RS-predictor : a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4. / Zaretzki, Jed; Bergeron, Charles; Rydberg, Patrik; Huang, Tao-wei; Bennett, Kristin P; Breneman, Curt M.

    In: Journal of Chemical Information and Modeling, Vol. 51, No. 7, 25.07.2011, p. 1667-1689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines. / Nielsen, Simon Dalsgaard; Smith, Garrick P; Begtrup, Mikael; Kristensen, Jesper Langgaard.

    In: Tetrahedron, Vol. 67, No. 29, 22.07.2011, p. 5261-5267.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew D; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 19.07.2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol. / Madsen, Karsten Kirkegaard; Ebert, Bjarke; Clausen, Rasmus Prætorius; Krogsgaard-Larsen, Povl; Schousboe, Arne; White, H Steve.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 338, No. 1, 01.07.2011, p. 214-219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Temocene: the porphycene analogue of temoporfin (Foscan®). / Garcia-Diaz, Maria; Sanchez-Garcia, David; Nonell, Santi; Soriano, Jorge; Villanueva, Angeles; Stockert, Juan Carlos; Canete, Magdalena; Sagrista, Maria Lluisa; Mora, Margarita.

    In: MedChemComm, Vol. 2, No. 7, 01.07.2011, p. 616-619.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Chemical composition and biological screening of Capsella bursa-pastoris. / Grosso, Clara; Vinholes, Juliana; Silva, Luis R; Guedes de Pinho, Paula; Goncalves, Rui F; Valentao, Patricia; Jäger, Anna K; Andrade, Paula B.

    In: Revista Brasileira de Farmacognosia, Vol. 21, No. 4, 07.2011, p. 635-644.

    Research output: Contribution to journalJournal articleResearchpeer-review

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