Research areas

  1. Published

    High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: quality by design optimization and characterization

    Cun, D., Jensen, D. M. K., Maltesen, M. J., Bunker, M., Whitside, P., Scurr, D., Foged, Camilla & Nielsen, Hanne Mørck, 2011, In : European Journal of Pharmaceutics and Biopharmaceutics. 77, 1, p. 26-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    High resolution crystal structures of the p120 RasGAP SH3 domain

    Ross, B., Kristensen, O., Favre, D., Walicki, J., Kastrup, Jette Sandholm Jensen, Widmann, C. & Gajhede, Michael, 2007, In : Biochemical and Biophysical Research Communications. 353, 2, p. 463-468

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor

    Krzywkowski, K. M., Davies, P. A., Feinberg-Zadek, P. L., Bräuner-Osborne, Hans & Jensen, Anders A., 2008, In : Proceedings of the National Academy of Science of the United States of America. 105, 2, p. 722-727

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    High-throughput small angle X-ray scattering from proteins in solution using a microfluidic front-end

    Toft, K. N., Vestergaard, Bente, Nielsen, S. S., Snakenborg, D., Jeppesen, M. G., Jacobsen, J. K., Arleth, Lise & Kutter, J. P., 2008, In : Analytical Chemistry. 80, 10, p. 3648-3654 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post-status epilepticus

    Rowley, N. M., Smith, M. D., Lamb, J. G., Schousboe, Arne & White, H. S., 2011, In : Journal of Neurochemistry. 117, 1, p. 82-90

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Histone demethylases

    Clausen, Rasmus Prætorius, Pedersen, Marianne Terndrup & Helin, Kristian, 2009, Epigenetic targets in drug discovery. Sippl, W. & Jung, M. (eds.). Weinheim: Wiley-VCH, Vol. 42. p. 269-290 (Methods and Principles in Medicinal Chemistry, Vol. 42).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  7. Published

    Histonhaler: et nyt mål inden for kræftbehandling

    Kristensen, Jesper Langgaard, Lohse, Brian & Clausen, Rasmus Prætorius, Dec 2010, In : Lægemiddelforskning. 2010, p. 7-9

    Research output: Contribution to journalJournal articleCommunication

  8. Published

    Hjernens forsvarsmur kortlagt og kopieret

    Helms, H. C., Waagepetersen, Helle S., Nielsen, C. U. & Brodin, Birger, 2010, In : Lægemiddelforskning. 2010, p. 22-24

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Homology modelling of the GABA transporter and analysis of tiagabine binding

    Skovstrup, S., Taboureau, O., Bräuner-Osborne, Hans & Jørgensen, Flemming Steen, 2010, In : ChemMedChem. 5, 7, p. 986-1000

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    How to engage experienced medicine users at the counter for a pharmacy-based asthma inhaler service

    Kaae, Susanne & Nørgaard, Lotte Stig, 2012, In : International Journal of Pharmacy Practice. 20, p. 99-106

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Human 5-HT3 receptors: implications of genetic variations, chaperone proteins, and subunit concatenation on function and expression

    Krzywkowski, K. M., 2008, København: Det Farmaceutiske Fakultet. 100 p.

    Research output: Book/ReportPh.D. thesisResearch

  12. Published

    Human phenotypically distinct TGFBI corneal dystrophies are linked to the stability of the fourth FAS1 domain of TGFBIp

    Runager, K., Basaiawmoit, R. V., Deva, T., Andreasen, M., Valnickova, Z., Sørensen, C. S., Karring, H., Thøgersen, I. B., Christiansen, G., Underhaug, J., Kristensen, T., Nielsen, N. C., Klintworth, G. K., Otzen, D. E. & Enghild, J. J., 18 Feb 2011, In : The Journal of Biological Chemistry. 286, 7, p. 4951-4958

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Human urinary excretion and metabolism of 82Se-enriched selenite and selenate determined by LC-ICP-MS

    Gammelgaard, Bente, Stürup, Stefan & Christensen, M. V., 2012, In : Metallomics. 4, 2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Human urine as test material in 1H NMR-based metabonomics: recommendations for sample preparation and storage

    Lauridsen, M., Hansen, S. H., Jaroszewski, J. W. & Cornett, Claus, 2007, In : Analytical Chemistry. 79, 3, p. 1181-1186

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Humid storage conditions increase the dissolution rate of diazepam from solid dispersions prepared by melt agglomeration

    Jørgensen, A. C. & Torstenson, A. S., 2008, In : Pharmaceutical Development and Technology. 13, 3, p. 187-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Hvad har varme at gøre med lægemidler?

    Olsen, L., Kasper, C., Kastrup, Jette Sandholm Jensen, Gajhede, Michael & Jørgensen, Flemming Steen, 2006, In : Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  17. Published

    Hydroxypropyl methylcellulose-controlled crystallization of erythromycin a dihydrate crystals with modified morphology

    Mirza, S., Miroshnyk, I., Heinämäki, J., Rantanen, Jukka, Antikainen, O., Vuorela, P., Vuorela, H. & Yliruusi, J., 2008, In : Crystal Growth & Design. 8, 10, p. 3526-3531

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Hylauronan-coated nanoparticles: the influence of the molecular weight on CD44-hyluronan interactions and on the immune response

    Mizrahy, S., Raz, S. R., Hasgaard, M., Liu , H., Soffer-Tsur, N., Cohen, K., Dvash, R., Landsman-Milo, D., Bremer, M. G. E. G., Moghimi, S. M. & Peer, D., 2011, In : Journal of Controlled Release. 156, 2, p. 231-238

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    Hyphenated NMR techniques

    Kesting, J. R., Kongstad, Kenneth Thermann & Jaroszewski, J. W., 2011, Biomolecular NMR spectroscopy. Dingley, A. J. & Pascal, S. M. (eds.). Amsterdam: IOS Press, Vol. 3. p. 413-434 (Advances in biomedical spectroscopy, Vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. Published

    Hyphenated NMR techniques and NMR-based metabolomics in studies of medicinal plants

    Jaroszewski, J. W., 2007.

    Research output: Contribution to conferencePosterResearch

  22. Published

    Hyphenated NMR, methods and applications

    Jaroszewski, J. W., 2010, Encyclopedia of spectroscopy and spectrometry. Lindon, J., Tranter, G. & Koppenaal, D. (eds.). 2 ed. Oxford: Academic Press, Vol. 1. p. 979-983

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  23. Published

    Hyphenated spectroscopy as a polymorph screening tool

    Aaltonen, J., Strachan, C. J., Pöllänen, K., Yliruusi, J. & Rantanen, Jukka, 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 44, 2, p. 477-483

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Hypoglemic activity of Iraqi Rheum ribes root extract

    Naqishbandi, A. M., Josefsen, K., Pedersen, M. E. & Jäger, A. K., 2009, In : Pharmaceutical Biology. 47, 5, p. 380-383

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Hyraceum, the fossilized metabolic product of rock hyraxes (Procavia capensis), shows GABA-benzodiazepine receptor affinity

    Olsen, A., Prinsloo, L. C., Scott, L. & Jäger, A. K., 2008, In : South African Journal of Science. 103, 11/12, p. 437-438

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Håb om at ramme latente bakterier i deres skjul

    Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In : Lægemiddelforskning 2012. 2012, p. 12-14

    Research output: Contribution to journalJournal articleResearch

  27. Published

    I-125 used for labelling of proteins in an absorption model changes the absorption rate of insulin aspart

    Søhoel, A., Plum, A., Frøkjær, Sven & Thygesen, P., 2007, In : Internation Journal of Pharmaceutics. 330, 1-2, p. 114-120

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Ibuprofen is a non-competitive inhibitor of the peptide transporter hPEPT1 (SLC15A1): possible interactions between hPEPT1 substrates and ibuprofen

    Omkvist, Diana Højmark, Brodin, Birger & Nielsen, C. U., 2010, In : British Journal of Pharmacology. 161, 8, p. 1793-1805

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published
  30. Published

    Identification of CYP1A2 ligands by structure-based and ligand-based virtual screening

    Poongavanam, V., Lastdrager, J., Oostenbrink, C., Commandeur, J. N. M., Vermeulen, N. P. E., Jørgensen, Flemming Steen & Olsen, L., 2011, In : MedChemComm. 2, 9, p. 853-859

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Identification of Sb(V) complexes in biological and food matrixes and their stibine formation efficiency during hydride generation with ICPMS detection

    Hansen, H. R. & Pergantis, S. A., 2007, In : Analytical Chemistry. 79, 14, p. 5304-5311

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Identification of a putative binding site for 5-alkyl-benzothiadiazides in the AMPA receptor dimer interface

    Harpsøe, Kasper, Varming, T., Gouliaev, A. H., Peters, D. & Liljefors, T., 2007, In : Journal of Molecular Graphics and Modelling. 26, 1, p. 213-225 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Identification of adulterants in a Chinese herbal medicine by LC-HRMS and LC-MS-SPE/NMR and comparative in vivo study with standards in a hypertensive rat model

    Kesting, J. R., Huang, J. & Sørensen, D., 2010, In : Journal of Pharmaceutical and Biomedical Analysis. 51, 3, p. 705-711

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Identification of natural products using HPLC-SPE combined with CapNMR

    Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In : Analytical Chemistry. 79, 2, p. 727-735

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid

    Larsen, J. T., Stærk, Dan, Cornett, Claus, Hansen, S. H. & Jaroszewski, J. W., 2009, In : Journal of Pharmaceutical and Biomedical Analysis. 49, p. 839-842

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Identifying sources of batch to batch variation in processability

    Hagsten, A., Larsen, C. C., Møller-Sonnergaard, J., Rantanen, Jukka & Hovgaard, L., 2008, In : Powder Technology. 183, 2, p. 213-219

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Iminolactones as Tools for Inversion of the Absolute Configuration of alpha-Amino Acids and as Inhibitors of Cancer Cell Proliferation

    Jensen, C. M., Chow, H., Chen, M., Zhai, L., Frydenvang, Karla Andrea, Liu, H., Franzyk, Henrik & Christensen, Søren Brøgger, 2016, In : European Journal of Medicinal Chemistry. 114, p. 118-133 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Immunity by formulation design: induction of high CD8+ T-cell responses by poly (I:C) incorporated into the CAF01 adjuvant via a double emulsion method

    Nordly, P. J., Rose, F., Christensen, D., Nielsen, Hanne Mørck, Andersen, P., Agger, E. M. & Foged, Camilla, 2011, In : Journal of Controlled Release. 150, 3, p. 307-317

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  40. Published

    Immunomodulatory effects of honey cannot be distinguished from endotoxin

    Timm, M., Bartelt, S. & Hansen, E. W., 2008, In : Cytokine. 42, 1, p. 113-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Impact of adult atopic dermatitis on topical drug penetration: assessment by cutaneous microdialysis and tape stripping

    Garcia Ortiz, P., Hansen, S. H., Shah, V. P., Menné, T. & Benfeldt, E., 2009, In : Acta Dermato Venereologica. 89, 1, p. 33-38 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Impact of bias discrepancy and amino acid usage on estimates of the effective number of codons used in a gene, and a test for selection on codon usage

    Fuglsang, A., 2007, In : Gene. 410, 1, p. 82-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Impact of carriers in oral absorption: permaeation across Caco-2 cells for the organic anions estrone-3-sulfate and glipizide

    Gram, L. K., Rist, G. M., Lennernäs, H. & Steffansen, B., 2009, In : European Journal of Pharmaceutical Sciences. 37, p. 378-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Impact of lipolysis on absorption of a poorly soluble model drug formulated in SMEDDS - an in vitro study

    Eriksson, A. H., Refsgaard, L., Larsen, A. T., Mullertz, Anette & Olesen, P. H., Nov 2010.

    Research output: Contribution to conferencePosterResearch

  45. Published

    Impact of the malate-aspartate shuttle in glutamate neurotransmission

    Waagepetersen, Helle S., Bak, Lasse Kristoffer, Lund, Trine Meldgaard, Walls, A. B., Sonnewald, U. & Schousboe, Arne, 2009, In : Journal of Neurochemistry. s1, p. 9

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    Impact of transporters in oral absorption: a case study of in vitro and in vivo organic anion absorption

    Gram, L. K., Rist, G. M. & Steffansen, B., 2009, In : Molecular Pharmaceutics. 6, 5, p. 1457-1465

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists

    Hansen, K. B., Mullasseril, P., Dawit, S., Kurtkaya, N. L., Yuan, H., Vance, K. M., Orr, A. G., Kvist, T., Ogden, K. K., Le, P., Vellano, K. M., Lewis, I., Kurtkaya, S., Du, Y., Qui, M., Murphy, T. J., Snyder, J. P., Bräuner-Osborne, Hans & Traynelis, S. F., 2010, In : Journal of Pharmacology and Experimental Therapeutics. 333, 3, p. 650-662

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Implementation of a process analytical technology system in a freeze-drying process using raman spectroscopy for in-line process monitoring

    De Beer, T. R. M., Allesø, M., Goethals, F., Coppens, A., Vander Heyden, Y., Diego, H. L. D., Rantanen, Jukka, Verpoort, F., Vervaet, C., Remon, J. P. & Baeyens, W. R. G., 2007, In : Bunseki. 79, 21, p. 7992-8003

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Implementation of droplet-membrane-droplet liquid-phase microextraction under stagnant conditions for lab-on-a-chip applications

    Sikanen, T., Pedersen-Bjergaard, Stig, Jensen, Henrik, Kostiainen, R., Rasmussen, K. E. & Kotiaho, T., 2010, In : Analytica Chimica Acta. 658, p. 133-140

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Improvement of urinary tract infection care in Swedish nursing homes from 2006 to 2010

    Honoré, P. G. H., Andersson, O., Eklund, Å., Eriksson, C., Hellmann, J., Norrdah, C., Ekman, G. S., Twerin, I. & Sylwan, S., 2011, In : Journal of Community Medicine and Health Education. 1, 2, 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review