Research areas

  1. Published

    Danish pain specialists' rationales behind the choice of fentanyl transdermal patches and oral transmucosal systems-A Delphi study. / Jacobsen, Ramune; Møldrup, Claus; Christrup, Lona.

    In: Pain Medicine, Vol. 10, No. 8, 2009, p. 1442-1451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example. / Chi, Celestine N; Bach, Anders; Gottschalk, Marie; Kristensen, Anders Skov; Strømgaard, Kristian; Jemth, Per.

    In: Journal of Biological Chemistry, Vol. 285, No. 36, 2010, p. 28252-28260.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design. / Gloriam, David Erik Immanuel; Foord, Steven M; Blaney, Frank E; Garland, Stephen L.

    In: Journal of Medicinal Chemistry, Vol. 52, No. 14, 2009, p. 4429-4442.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. / Lehre, A C; Rowley, N M; Zhou, Y; Holmseth, S; Guo, C; Holen, T; Hua, R; Laake, P; Olofsson, A M; Poblete-Naredo, I; Rusakov, D A; Madsen, Karsten Kirkegaard; Clausen, Rasmus Prætorius; Schousboe, Arne; White, H Steve; Danbolt, N C.

    In: Epilepsy Research, Vol. 95, No. 1-2, 01.06.2011, p. 70-81.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration. / Wen, Yanhong; Grøndahl, Lisbeth; Gallego, Monica R.; Jørgensen, Lene; Møller, Eva Horn; Nielsen, Hanne Mørck.

    In: Biomacromolecules, Vol. 13, 2012, p. 905-917.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Delivery technologies for biopharmaceuticals : a critical assessment. / Van De Weert, Marco.

    Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. ed. / Lene Jørgensen; Hanne Mørck Nielsen. Chichester : Wiley, 2009. p. 407-411.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  7. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex. / Leke, Renata; Bak, Lasse Kristoffer; Schousboe, Arne; Waagepetersen, Helle Sønderby.

    In: Neurochemical Research, Vol. 33, No. 12, 2008, p. 2629-2635.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin. / Jensen, Linda Boye; Nielsen, Hanne Mørck; Foged, Camilla.

    In: Lægemiddelforskning, 2008, p. 13-15.

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Desaturation of excess intramyocellular triacylglycerol in obesity : implications for glycemic control. / Haugaard, S B; Madsbad, S; Mu, Huiling; Vaag, A.

    In: International Journal of Obesity, Vol. 34, No. 3, 2010, p. 500-510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Description of aquatic ecosystem's development by eco-exergy and exergy destruction. / Jørgensen, Sven Erik.

    In: Ecological Modelling, Vol. 204, No. 1-2, 2007, p. 22-28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Design and synthesis of dimeric ligands : optimization of selectivity and potency of glutamate receptor ligands. / Thorsen, Birgitte Høiriis Kaae.

    København : Det Farmaceutiske Fakultet, 2009. 154 p.

    Research output: Book/ReportPh.D. thesisResearch

  12. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction. / Bach, Anders; Chi, Celestine N; Pang, Gar Fai; Olsen, Lars; Kristensen, Anders Skov; Jemth, Per; Strømgaard, Kristian.

    In: Angewandte Chemie - International Edition, Vol. 48, No. 51, 2009, p. 9685-9689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Design and synthesis of new 1-hydroxypyrazole-based ligands for characterizing the GABAA receptor orthosteric binding site. / Hansen, Henriette Møller.

    København : Det Farmaceutiske Fakultet, 2009. 156 p.

    Research output: Book/ReportPh.D. thesisResearch

  14. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain. / Hansen, Martin.

    København : Det Farmaceutiske Fakultet, 2010. 207 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published

    Design and synthesis of subtype selective ligands for the human excitatory amino acid transporters (EAATs) and design and synthesis of novel selective phosphodiesterase 10A (PDE10A) inhibitors. / Erichsen, Mette Norman.

    København : Det Farmaceutiske Fakultet, 2011. 158 p.

    Research output: Book/ReportPh.D. thesisResearch

  16. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA. / Jensen, Ditte Marie Krohn; Jensen, Linda Boye; Koocheki, Saeid; Cun, Dongmei; Nielsen, Hanne Mørck; Foged, Camilla; Bengtson, Lasse.

    In: Journal of Controlled Release, Vol. 157, No. 1, 2012, p. 141-148.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor. / Knudsen, Nina Østergaard; Schiffelers, Raymond M.; Jørgensen, Lene; Hansen, Jens; Frøkjær, Sven; Foged, Camilla.

    In: International Journal of Pharmaceutics, Vol. 428, No. 1-2, 2012, p. 171-177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Design space approach in the optimization of the spray-drying process. / Lebrun, Pierre; Krier, Fabrice; Mantanus, Jérôme ; Grohganz, Holger; Yang, Mingshi; Rozet, Eric; Boulanger, Bruno; Evrard, Brigitte; Rantanen, Jukka; Hubert, Philippe.

    In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 80, No. 1, 2012.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Design, synthesis and pharmacological characterization of ligands for the neuronal nicotinic acetylcholine receptors. / Hansen, Camilla Petrycer.

    København : Det Farmaceutiske Fakultet, 2009. 158 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Design, synthesis and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands. / Lund, Birgitte Winther.

    København : Det Farmaceutiske Fakultet, 2007. 197 p.

    Research output: Book/ReportPh.D. thesisResearch

  21. Published

    Design, synthesis, and evaluation of tripeptidic promoieties targeting the intestinal peptide transporter hPEPT1. / Thorn, Karina; Andersen, Rikke; Christensen, Jon; Jacobsen, Palle; Nielsen, Carsten Uhd; Steffansen, Bente; Begtrup, Mikael.

    In: ChemMedChem, Vol. 2, No. 4, 2007, p. 479-487.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Design, synthesis, and in vitro pharmacology of new radiolabeled ¿-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity ¿-hydroxybutyric acid binding sites. / Sabbatini, Paola; Wellendorph, Petrine; Høg, Signe; Pedersen, Martin Holst Friborg; Bräuner-Osborne, Hans; Martiny, Lars; Frølund, Bente Flensborg; Clausen, Rasmus Prætorius.

    In: Journal of Medicinal Chemistry, Vol. 53, No. 17, 2010, p. 6506-6510.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors. / Dallanoce, Clelia; Magrone, Pietro; Matera, Carlo; Frigerio, Fabio; Grazioso, Giovanni; De Amici, Marco; Fucile, Sergio; Piccari, Vanessa; Frydenvang, Karla Andrea; Pucci, Luca; Gotti, Cecilia; Clementi, Francesco; De Micheli, Carlo.

    In: ChemMedChem, Vol. 6, No. 5, 02.05.2011, p. 889-903.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor ß ligands. / Lund, Birgitte W.; Knapp, Anne Eeg; Piu, Fabrice; Gauthier, Natalie K; Begtrup, Mikael; Hacksell, Uli; Olsson, Roger.

    In: Journal of Medicinal Chemistry, Vol. 52, No. 6, 2009, p. 1540-1545.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Determination of 2,6-dichlorobenzamide and its degradation products in water samples using solid-phase exctraction followed by liquid chromatography-tandem mass spectrometry. / Anskjær, Gitte Gotholdt; Björklund, Bengt Erland; Simonsen, Allan; Halling-Sørensen, Bent.

    In: Journal of Chromatography A, Vol. 1216, 2009, p. 5199-5206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Determination of abiotic and microbial transformation products of ivermectin. / Sporring, Sune Hove; Krogh, Kristine Andersen; Jensen, G. G.; Raich-Montiu, J.; Halling-Sørensen, Bent.

    2007. Poster session presented at International Conference on Pharmaceuticals in the Environment, York, United Kingdom.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Determination of amorphous content in the pharmaceutical process environment. / Savolainen, Marja; Jouppila, Kirsi; Pajamo, Outi; Christiansen, Leena; Strachan, Clare; Karjalainen, Milja; Rantanen, Jukka Tapio.

    In: Journal of Pharmacy and Pharmacology, Vol. 59, No. 2, 2007, p. 161-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis. / Anderot, Maria; Nilsson, Mikael; Végvári, Ákos; Møller, Eva Horn; Van De Weert, Marco; Isaksson, Ronald.

    In: Journal of Chromatography - B, Vol. 877, 2009, p. 892-896.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Determination of ivermectin and transformation products in environmental waters using hollow fibre-supported liquid membrane extraction and liquid chromatography-mass spectrometry/mass spectrometry. / Raich-Montiu, J.; Krogh, Kristine Andersen; Granados, M.; Jönsson, J.Å.; Halling-Sørensen, Bent.

    In: Journal of Chromatography A, Vol. 1187, No. 1-2, 2008, p. 275-280.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection. / Olsen, Karen-Marie; Hansen, Steen Honore'; Sidenius, Ulrik; Schmiegelow, K.

    In: Journal of Chromatography - B, Vol. 864, No. 1-2, 2008, p. 149-155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis. / Franzen, Ulrik; Jørgensen, Lene; Larsen, Claus Selch; Heegaard, Niels H. H.; Østergaard, Jesper.

    In: Electrophoresis, Vol. 30, No. 15, 2009, p. 2711-2719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Determination of pharmaceuticals in environmental and biological matrices using pressurised liquid extraction - Are we developing sound extraction  methods ? / Runnqvist, Hannah Elisabeth Sigrid; Bak, Søren Alex; Hansen, Martin; Styrishave, Bjarne; Halling-Sørensen, Bent; Björklund, Bengt Erland.

    In: Journal of Chromatography A, Vol. 1217, No. 16, 2010, p. 2447-2470.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Determination of protein conformation by isotopically labelled cross-linking and dedicated software: Application to the chaperone, calreticulin. / Nielsen, Tina; Thaysen-Andersen, Morten; Larsen, Nanna; Jørgensen, Flemming Steen; Houen, Gunnar; Højrup, Peter.

    In: International Journal of Mass Spectrometry, Vol. 268, No. 2-3, 2007, p. 217-226.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Determination of steroid hormones in blood by GC-MS/MS. / Hansen, Martin; Jacobsen, Naja Wessel; Nielsen, Frederik Knud; Björklund, Erland; Styrishave, Bjarne; Halling-Sørensen, Bent.

    In: Analytical and Bioanalytical Chemistry, Vol. 400, 2011, p. 3409-3417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection. / Zimmermann, Anne; Elema, Michiel Ringkjøbing; Hansen, Tue; Müllertz, Anette; Hovgaard, Lars.

    In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 44, No. 4, 2007, p. 874-880.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Determination of ten steroid hormones in animal waste manure and agricultural soil using inverse and integrated clean-up pressurized liquid extraction and gas chromatography-tandem mass spectrometry. / Hansen, Martin; Krogh, Kristine Andersen; Halling-Sørensen, Bent; Björklund, Bengt Erland.

    In: Analytical Methods, Vol. 3, 2011, p. 1087-1095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Determination of the binding sites for oxaliplatin on insulin using mass spectrometry-based approaches. / Møller, Charlotte; Sprenger, Richard R.; Stürup, Stefan; Højrup, Peter.

    In: Analytical and Bioanalytical Chemistry, Vol. 401, 2011, p. 1619-1629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Developing a generic, individualised adherence programme for chronic medication users. / Herborg, Hanne; Haugbølle, Lotte Stig; Sørensen, Lene; Rossing, Charlotte; Dam, Pernille.

    In: Pharmacy Practice, Vol. 6, No. 3, 2008, p. 148-157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism. / Madsen, Kim Grimstrup; Olsen, Jørgen; Skonberg, Christian; Hansen, Steen Honoré; Jurva, Ulrik.

    In: Chemical Research in Toxicology, Vol. 20, No. 5, 2007, p. 821-831.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice. / Murillo-Arbizu, M.; González-Peñas, E.; Hansen, Steen Honore'; Amézqueta, S.; Østergaard, Jesper.

    In: Food and Chemical Toxicology, Vol. 46, No. 6, 2008, p. 2251-2257.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Brandt, Asbjørn; Halling-Sørensen, Bent; Björklund, Erland.

    In: International Journal of Environmental Analytical Chemistry, Vol. 93, No. 14, 25.02.2013, p. 1500-1512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Development and validation of rapid resolution RP-HPLC Method for simultaneous determination of atorvastatin and related compounds by use of chemometrics. / Petkovska, Rumenka; Cornett, Claus; Dimitrovska, Aneta.

    In: Analytical Letters, Vol. 41, No. 6, 2008, p. 992-1009.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Development of a new rapid method for in vitro detection of pyrogenic substances. / Timm, Michael.

    København : Museum Tusculanum, 2009. 65 p.

    Research output: Book/ReportPh.D. thesisResearch

  44. Published

    Development of a qualitative exploratory case study research method to explore sustained delivery of cognitive services. / Kaae, Susanne; Søndergaard, Birthe; Haugbølle, Lotte Stig; Traulsen, Janine Marie.

    In: Pharmacy World and Science, Vol. 32, 2010, p. 36-42.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity. / Otto, Marie; Hansen, Steen Honore'; Dalgaard, L.; Dubois, J.; Badolo, Lassina.

    In: Cell Biology and Toxicology, Vol. 24, No. 1, 2008, p. 87-99.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Development of an N-O linker for fluorous phase chemistry & fluorous parallel synthesis of a piperazinedione fused tricyclic compound library. / Nielsen, Simon Dalsgaard.

    København : Det Farmaceutiske Fakultet, 2009. 161 p.

    Research output: Book/ReportPh.D. thesisResearch

  47. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry. / Krogh, Kristine Andersen; Björklund, Bengt Erland; Loeffler, D.; Fink, G.; Halling-Sørensen, Bent; Ternes, T.A.

    In: Journal of Chromatography A, Vol. 1211, No. 1-2, 2008, p. 60-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Development of personal desiderata while learning GIS. / Madsen, Lene Møller; Christiansen, Frederik V; Rump, Camilla Østerberg.

    Frontiers in Science Education Research: Proceedings of the Frontiers in Science Education Research Conference 22 - 24 March 2009, Famagusta, North Cyprus. ed. / Ayhan Bisel; Mehmet U. Garib. Eastern Mediterranean University Press, 2009. p. 441-450.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  49. Published

    Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model : assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms. / Lind, Marianne Ladegaard; Jacobsen, Jette; Holm, Rene; Müllertz, Anette.

    In: European Journal of Pharmaceutical Sciences, Vol. 32, No. 4-5, 2007, p. 261-270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development of solid-phase aziridine chemistries : Piperazine scaffolds and unnatural amino acid building blocks. / Ottesen, Lars Korsgaard.

    København : Det Farmaceutiske Fakultet, 2010. 139 p.

    Research output: Book/ReportPh.D. thesisResearch

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