Research areas

  1. Published

    Danish pain specialists' rationales behind the choice of fentanyl transdermal patches and oral transmucosal systems-A Delphi study

    Jacobsen, Ramune, Møldrup, C. & Christrup, Lona Louring, 2009, In : Pain Medicine. 10, 8, p. 1442-1451

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In : Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Definition of the G protein-coupled receptor transmembrane bundle binding pocket and calculation of receptor similarities for drug design

    Gloriam, David E., Foord, S. M., Blaney, F. E. & Garland, S. L., 2009, In : Journal of Medicinal Chemistry. 52, 14, p. 4429-4442

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In : Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Delivery of dermatan sulfate from polyelectrolyte complex-containing alginate composite microspheres for tissue regeneration

    Wen, Y., Grøndahl, L., Gallego, M. R., Jørgensen, Lene, Møller, E. H. & Nielsen, Hanne Mørck, 2012, In : Biomacromolecules. 13, p. 905-917

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Delivery technologies for biopharmaceuticals: a critical assessment

    van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  7. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In : Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Dendritiske nanostrukturer som transportører af genestisk medicin

    Jensen, L. B., Nielsen, Hanne Mørck & Foged, Camilla, 2008, In : Lægemiddelforskning. p. 13-15

    Research output: Contribution to journalJournal articleCommunication

  9. Published

    Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control

    Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, A., 2010, In : International Journal of Obesity. 34, 3, p. 500-510 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Description of aquatic ecosystem's development by eco-exergy and exergy destruction

    Jørgensen, S. E., 2007, In : Ecological Modelling. 204, 1-2, p. 22-28

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Design and synthesis of dimeric ligands: optimization of selectivity and potency of glutamate receptor ligands

    Thorsen, B. H. K., 2009, København: Det Farmaceutiske Fakultet. 154 p.

    Research output: Book/ReportPh.D. thesisResearch

  12. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In : Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Design and synthesis of new 1-hydroxypyrazole-based ligands for characterizing the GABAA receptor orthosteric binding site

    Hansen, H. M., 2009, København: Det Farmaceutiske Fakultet. 156 p.

    Research output: Book/ReportPh.D. thesisResearch

  14. Design and synthesis of selective serotonin receptor agonists for positron emission tomography imaging of the brain

    Hansen, M., 16 Dec 2010, København: Det Farmaceutiske Fakultet. 207 p.

    Research output: Book/ReportPh.D. thesisResearch

  15. Published
  16. Published

    Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA

    Jensen, D. M. K., Jensen, L. B., Koocheki, S., Cun, D., Nielsen, Hanne Mørck, Foged, Camilla & Bengtson, L., 2012, In : Journal of Controlled Release. 157, 1, p. 141-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin a2ß1 receptor

    Knudsen, N. Ø., Schiffelers, R. M., Jørgensen, Lene, Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In : International Journal of Pharmaceutics. 428, 1-2, p. 171-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Design space approach in the optimization of the spray-drying process

    Lebrun, P., Krier, F., Mantanus, J., Grohganz, Holger, Yang, Mingshi, Rozet, E., Boulanger, B., Evrard, B., Rantanen, Jukka & Hubert, P., 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 80, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Design, synthesis and pharmacological characterization of ligands for the neuronal nicotinic acetylcholine receptors

    Hansen, C. P., 2009, København: Det Farmaceutiske Fakultet. 158 p.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Design, synthesis and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands

    Lund, B. W., 2007, København: Det Farmaceutiske Fakultet. 197 p.

    Research output: Book/ReportPh.D. thesisResearch

  21. Published

    Design, synthesis, and evaluation of tripeptidic promoieties targeting the intestinal peptide transporter hPEPT1

    Thorn, K., Andersen, R., Christensen, J., Jacobsen, P., Nielsen, C. U., Steffansen, B. & Begtrup, M., 2007, In : ChemMedChem. 2, 4, p. 479-487

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Design, synthesis, and in vitro pharmacology of new radiolabeled ¿-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity ¿-hydroxybutyric acid binding sites

    Sabbatini, P., Wellendorph, Petrine, Høg, S., Pedersen, M. H. F., Bräuner-Osborne, Hans, Martiny, L., Frølund, Bente & Clausen, Rasmus Prætorius, 2010, In : Journal of Medicinal Chemistry. 53, 17, p. 6506-6510

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Delta2 -isoxazoline derivatives as potent and selective agonists of alpha7 nicotinic acetylcholine receptors

    Dallanoce, C., Magrone, P., Matera, C., Frigerio, F., Grazioso, G., De Amici, M., Fucile, S., Piccari, V., Frydenvang, Karla Andrea, Pucci, L., Gotti, C., Clementi, F. & De Micheli, C., 2 May 2011, In : ChemMedChem. 6, 5, p. 889-903

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor ß ligands

    Lund, B. W., Knapp, A. E., Piu, F., Gauthier, N. K., Begtrup, M., Hacksell, U. & Olsson, R., 2009, In : Journal of Medicinal Chemistry. 52, 6, p. 1540-1545

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Determination of 2,6-dichlorobenzamide and its degradation products in water samples using solid-phase exctraction followed by liquid chromatography-tandem mass spectrometry

    Anskjær, G. G., Björklund, B. E., Simonsen, A. & Halling-Sørensen, B., 2009, In : Journal of Chromatography A. 1216, p. 5199-5206

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Determination of abiotic and microbial transformation products of ivermectin

    Sporring, S. H., Krogh, K. A., Jensen, G. G., Raich-Montiu, J. & Halling-Sørensen, B., 2007.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Determination of amorphous content in the pharmaceutical process environment

    Savolainen, M., Jouppila, K., Pajamo, O., Christiansen, L., Strachan, C., Karjalainen, M. & Rantanen, Jukka, 2007, In : Journal of Pharmacy and Pharmacology. 59, 2, p. 161-170

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Determination of dissociation constants between polyelectrolytes and proteins by affinity capillary electrophoresis

    Anderot, M., Nilsson, M., Végvári, Á., Møller, E. H., van de Weert, Marco & Isaksson, R., 2009, In : Journal of Chromatography - B. 877, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Determination of ivermectin and transformation products in environmental waters using hollow fibre-supported liquid membrane extraction and liquid chromatography-mass spectrometry/mass spectrometry

    Raich-Montiu, J., Krogh, K. A., Granados, M., Jönsson, J. Å. & Halling-Sørensen, B., 2008, In : Journal of Chromatography A. 1187, 1-2, p. 275-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Determination of leukocyte DNA 6-thioguanine nucleotide levels by high-performance liquid chromatography with fluorescence detection

    Olsen, K., Hansen, S. H., Sidenius, U. & Schmiegelow, Kjeld, 2008, In : Journal of Chromatography - B. 864, 1-2, p. 149-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis

    Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In : Electrophoresis. 30, 15, p. 2711-2719

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Determination of pharmaceuticals in environmental and biological matrices using pressurised liquid extraction - Are we developing sound extraction  methods ?

    Runnqvist, H. E. S., Bak, S. A., Hansen, M., Styrishave, Bjarne, Halling-Sørensen, B. & Björklund, B. E., 2010, In : Journal of Chromatography A. 1217, 16, p. 2447-2470

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Determination of protein conformation by isotopically labelled cross-linking and dedicated software: Application to the chaperone, calreticulin

    Nielsen, T., Thaysen-Andersen, M., Larsen, N., Jørgensen, Flemming Steen, Houen, G. & Højrup, P., 2007, In : International Journal of Mass Spectrometry. 268, 2-3, p. 217-226

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Determination of steroid hormones in blood by GC-MS/MS

    Hansen, M., Jacobsen, N. W., Nielsen, F. K., Björklund, E., Styrishave, Bjarne & Halling-Sørensen, B., 2011, In : Analytical and Bioanalytical Chemistry. 400, p. 3409-3417

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection

    Zimmermann, A., Elema, M. R., Hansen, T., Mullertz, Anette & Hovgaard, L., 2007, In : Journal of Pharmaceutical and Biomedical Analysis. 44, 4, p. 874-880

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Determination of ten steroid hormones in animal waste manure and agricultural soil using inverse and integrated clean-up pressurized liquid extraction and gas chromatography-tandem mass spectrometry

    Hansen, M., Krogh, K. A., Halling-Sørensen, B. & Björklund, B. E., 2011, In : Analytical Methods. 3, p. 1087-1095

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Determination of the binding sites for oxaliplatin on insulin using mass spectrometry-based approaches

    Møller, C., Sprenger, R. R., Stürup, Stefan & Højrup, P., 2011, In : Analytical and Bioanalytical Chemistry. 401, p. 1619-1629

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Developing a generic, individualised adherence programme for chronic medication users

    Herborg, H., Nørgaard, Lotte Stig, Sørensen, L., Rossing, C. & Dam, P., 2008, In : Pharmacy Practice. 6, 3, p. 148-157

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism

    Madsen, K. G., Olsen, J., Skonberg, C., Hansen, S. H. & Jurva, U., 2007, In : Chemical Research in Toxicology. 20, 5, p. 821-831

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice

    Murillo-Arbizu, M., González-Peñas, E., Hansen, S. H., Amézqueta, S. & Østergaard, Jesper, 2008, In : Food and Chemical Toxicology. 46, 6, p. 2251-2257

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices

    Bak, S. A., Hansen, M., Krogh, K. A., Brandt, A., Halling-Sørensen, B. & Björklund, E., 25 Feb 2013, In : International Journal of Environmental Analytical Chemistry. 93, 14, p. 1500-1512

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Development and validation of rapid resolution RP-HPLC Method for simultaneous determination of atorvastatin and related compounds by use of chemometrics

    Petkovska, R., Cornett, Claus & Dimitrovska, A., 2008, In : Analytical Letters. 41, 6, p. 992-1009

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Development of a new rapid method for in vitro detection of pyrogenic substances

    Timm, M., 2009, København: Museum Tusculanum. 65 p.

    Research output: Book/ReportPh.D. thesisResearch

  44. Published

    Development of a qualitative exploratory case study research method to explore sustained delivery of cognitive services

    Kaae, Susanne, Søndergaard, B., Nørgaard, Lotte Stig & Traulsen, Janine Marie, 2010, In : Pharmacy World and Science. 32, p. 36-42

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity

    Otto, M., Hansen, S. H., Dalgaard, L., Dubois, J. & Badolo, L., 2008, In : Cell Biology and Toxicology. 24, 1, p. 87-99

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Development of an N-O linker for fluorous phase chemistry & fluorous parallel synthesis of a piperazinedione fused tricyclic compound library

    Nielsen, S. D., 2009, København: Det Farmaceutiske Fakultet. 161 p.

    Research output: Book/ReportPh.D. thesisResearch

  47. Published

    Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry

    Krogh, K. A., Björklund, B. E., Loeffler, D., Fink, G., Halling-Sørensen, B. & Ternes, T. A., 2008, In : Journal of Chromatography A. 1211, 1-2, p. 60-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Development of personal desiderata while learning GIS

    Madsen, Lene Møller, Christiansen, Frederik Voetmann & Rump, Camilla Østerberg, 2009, Frontiers in Science Education Research: Proceedings of the Frontiers in Science Education Research Conference 22 - 24 March 2009, Famagusta, North Cyprus. Bisel, A. & Garib, M. U. (eds.). Eastern Mediterranean University Press, p. 441-450 9 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  49. Published

    Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms

    Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2007, In : European Journal of Pharmaceutical Sciences. 32, 4-5, p. 261-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development of solid-phase aziridine chemistries: Piperazine scaffolds and unnatural amino acid building blocks

    Ottesen, L. K., 2010, København: Det Farmaceutiske Fakultet. 139 p.

    Research output: Book/ReportPh.D. thesisResearch

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