Research areas

  1. Published

    Metabolic profiling based on two-dimensional J-resolved 1H NMR data and parallel factor analysis. / Yilmaz, Ali; Nyberg, Nils T; Jaroszewski, Jerzy W.

    In: Analytical Chemistry, Vol. 83, No. 21, 27.09.2011, p. 8278-8285.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures : HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study. / Kesting, Julie Regitze; Olsen, Lars; Stærk, Dan; Tejesvi, Mysore V; Kini, Kukkundoor R; Prakash, Harishchandra S; Jaroszewski, Jerzy W.

    In: Journal of Natural Products, Vol. 74, No. 10, 26.09.2011, p. 2206-2215.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A highly selective agonist for the metabotropic glutamate receptor mGluR2. / Nielsen, Simon Dalsgaard; Fulco, Marica; Serpi, Michaela; Nielsen, Birgitte; Hansen, Maria Brinck ; Hansen, Kasper Lind; Thomsen, Christian; Brodbeck, Robb; Bräuner-Osborne, Hans; Pellicciari, Roberto; Norrby, Per-Ola; Greenwood, Jeremy R; Clausen, Rasmus Prætorius.

    In: MedChemComm, Vol. 2, No. 11, 23.09.2011, p. 1120-1124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors. / Lohse, Brian; Nielsen, Anders L; Kristensen, Jan B L; Helgstrand, Charlotte; Cloos, Paul Andreas Compare; Olsen, Lars; Gajhede, Michael; Clausen, Rasmus Prætorius; Kristensen, Jesper Langgaard.

    In: Angewandte Chemie International Edition, Vol. 50, No. 39, 19.09.2011, p. 9100-9103.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effects of Teucrium polium spp. capitatum flavonoids on the lipid and carbohydrate metabolism in rats. / Stefkov, Gjoshe; Kulevanova, Svetlana; Miova, Biljana; Dinevska-Kjovkarovska, Suzana; Mølgaard, Per; Jäger, Anna K; Josefsen, Knud.

    In: Pharmaceutical Biology, Vol. 49, No. 9, 01.09.2011, p. 885-892.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons. / Dadsetan, Sherry; Bak, Lasse Kristoffer; Sørensen, Michael; Keiding, Susanne; Vilstrup, Hendrik; Ott, Peter; Leke, Renata; Schousboe, Arne; Waagepetersen, Helle S.

    In: Neurochemistry International, Vol. 59, No. 4, 01.09.2011, p. 482-8.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Ubiquitous plant compounds disturb cell-based assays. / Saaby, Lasse; Jäger, Anna K.

    In: Journal of Ethnopharmacology, Vol. 137, No. 1, 01.09.2011, p. 942-943.

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model. / Rasmussen, Rune Skovgaard; Overgaard, Karsten; Kristiansen, Uffe; Johansen, Flemming Fryd.

    In: Neurological Research, Vol. 33, No. 7, 09.2011, p. 774-782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Do two different reaction mechanisms contribute to the hydroxylation of primary amines by cytochrome P450? / Rydberg, Patrik; Olsen, Lars.

    In: Journal of Chemical Theory and Computation, Vol. 7, No. 10, 09.2011, p. 3399-3404.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evolution and applications of plant pathway resources and databases. / Sucaet, Yves; Deva, Taru.

    In: Briefings in Bioinformatics, Vol. 12, No. 5, 09.2011, p. 530-544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice. / Richner, Mette; Bjerrum, Ole Jannik; Nykjær, Anders; Vaegter, Christian B.

    In: Journal of Visualized Experiments, No. 54, 18.08.2011, p. e3092.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects. / Dam, Gitte; Keiding, Susanne; Munk, Ole Lajord; Ott, Peter; Buhl, Mads; Vilstrup, Hendrik; Bak, Lasse Kristoffer; Waagepetersen, Helle Sønderby; Schousboe, Arne; Møller, Niels; Sørensen, Michael.

    In: American Journal of Physiology: Gastrointestinal and Liver Physiology, Vol. 301, No. 2, 01.08.2011, p. G269-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Nicotine reverses anhedonic-like response and cognitive impairment in the rat chronic mild stress model of depression : comparison with sertraline. / Andreasen T., Jesper; Henningsen, Kim; Bate, Simon; Christiansen, Sofie; Wiborg, Ove.

    In: Journal of Psychopharmacology, Vol. 25, No. 8, 01.08.2011, p. 1134-41.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. / Lund, Trine Meldgaard; Obel, Linea F; Risa, Øystein; Sonnewald, Ursula.

    In: Neurochemistry International, Vol. 59, No. 2, 01.08.2011, p. 309-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Extraction and detection of Ionophores in the Aquatic Environment. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Björklund, Erland; Halling-Sørensen, Bent.

    2011. Abstract from 3rd EmCon 2011: International conference on analysis of emerging contaminants in the environment, Copenhagen, Denmark.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  16. Published

    Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging. / Ostergaard, Jesper; Ye, Fengbin; Rantanen, Jukka; Yaghmur, Anan; Larsen, Susan Weng; Larsen, Claus Selch; Jensen, Henrik.

    In: Journal of Pharmaceutical Sciences, Vol. 100, No. 8, 08.2011, p. 3405-3410.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1. / Thorn, Karina; Nielsen, Carsten Uhd; Jakobsen, Palle; Steffansen, Bente; Zercher, Charles K; Begtrup, Mikael.

    In: Bioorganic & Medicinal Chemistry Letters, Vol. 21, No. 15, 08.2011, p. 4597-4601.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Open3DALIGN : an open-source software aimed at unsupervised ligand alignment. / Tosco, Paolo; Balle, Thomas; Shiri, Fereshteh.

    In: Journal of Computer - Aided Molecular Design, Vol. 25, No. 8, 27.07.2011, p. 777-783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Unraveling the high- and low-sensitivity agonist responses of nicotinic acetylcholine receptors. / Harpsøe, Kasper; Ahring, Philip K; Christensen, Jeppe K; Jensen, Marianne L; Peters, Dan; Balle, Thomas.

    In: Journal of Neuroscience, Vol. 31, No. 30, 27.07.2011, p. 10759-10766.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    RS-predictor : a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4. / Zaretzki, Jed; Bergeron, Charles; Rydberg, Patrik; Huang, Tao-wei; Bennett, Kristin P; Breneman, Curt M.

    In: Journal of Chemical Information and Modeling, Vol. 51, No. 7, 25.07.2011, p. 1667-1689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines. / Nielsen, Simon Dalsgaard; Smith, Garrick P; Begtrup, Mikael; Kristensen, Jesper Langgaard.

    In: Tetrahedron, Vol. 67, No. 29, 22.07.2011, p. 5261-5267.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters. / Andersen, Jacob; Stuhr-Hansen, Nicolai; Zachariassen, Linda; Toubro, Søren; Hansen, Stinna Maria R; Eildal, Jonas Nii Nortey; Bond, Andrew D; Bøgesø, Klaus P; Bang-Andersen, Benny; Kristensen, Anders Skov; Strømgaard, Kristian.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 29, 19.07.2011, p. 12137-12142.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol. / Madsen, Karsten Kirkegaard; Ebert, Bjarke; Clausen, Rasmus Prætorius; Krogsgaard-Larsen, Povl; Schousboe, Arne; White, H Steve.

    In: Journal of Pharmacology and Experimental Therapeutics, Vol. 338, No. 1, 01.07.2011, p. 214-219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Temocene: the porphycene analogue of temoporfin (Foscan®). / Garcia-Diaz, Maria; Sanchez-Garcia, David; Nonell, Santi; Soriano, Jorge; Villanueva, Angeles; Stockert, Juan Carlos; Canete, Magdalena; Sagrista, Maria Lluisa; Mora, Margarita.

    In: MedChemComm, Vol. 2, No. 7, 01.07.2011, p. 616-619.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Chemical composition and biological screening of Capsella bursa-pastoris. / Grosso, Clara; Vinholes, Juliana; Silva, Luis R; Guedes de Pinho, Paula; Goncalves, Rui F; Valentao, Patricia; Jäger, Anna K; Andrade, Paula B.

    In: Revista Brasileira de Farmacognosia, Vol. 21, No. 4, 07.2011, p. 635-644.

    Research output: Contribution to journalJournal articleResearchpeer-review

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