Can DMCO Detect Visual Field Loss in Neurological Patients? A Secondary Validation Study

Research output: Contribution to journalJournal articleResearchpeer-review

Ane Sophie Olsen, Alvilda Thougaard Steensberg, Morten la Cour, Troels Wesenberg Kjaer, Bertil Damato, Lars Hageman Pinborg, Miriam Kolko

Unrecognized visual field loss is caused by a range of blinding eye conditions as well as serious brain diseases. The commonest cause of asymptomatic visual field loss is glaucoma. No screening tools have been proven cost-effective. Damato Multifixation Campimetry Online (DMCO), an inexpensive online test, has been evaluated as a future cost-beneficial tool to detect glaucoma. To further validate DMCO, this study aimed to test DMCO in a preselected population with neurological visual field loss. Methods: The study design was an evaluation of a diagnostic test. Patients were included if they had undergone surgery for epilepsy during 2011-2014, resulting in visual field loss. They were examined with DMCO and results were compared with those obtained with the Humphrey Field Analyzer (30:2 SITA-Fast). DMCO sensitivity and specificity were estimated with 95% confidence intervals. Results: The cohort comprised 40 patients (25 female and 15 male) with a mean age of 39 years (range 17-60 years). The mean visual acuity was >1.0 and all eyes had an intraocular pressure <21 mm Hg. Sensitivity and specificity of DMCO compared to the reference standard were 72.7 and 96.3%, respectively. Conclusions: DMCO detects moderate-to-severe homonymous quadrantanopia; it can be useful in settings where the current practice is confrontation visual field examination, and where standard conventional perimetry is not available.

Original languageEnglish
JournalOphthalmic Research
Volume58
Issue number2
Pages (from-to)85-93
Number of pages9
ISSN0030-3747
DOIs
Publication statusPublished - 2017

    Research areas

  • Advanced glycation end products, Genetics, Glaucoma, Open angle, Polymorphisms

ID: 182093302