Crystallization and preliminary X-ray analysis of a PNA-DNA complex
Research output: Contribution to journal › Journal article › Research › peer-review
Peptide nucleic acids (PNAs) are DNA mimics with a peptide backbone. PNAs are being intensely investigated owing to a potential as gene-targeted drugs. A PNA (H-GTAGATCACT-NH2)-DNA (5'-AGTGATCTAC-3') complex has been crystallized in a tetragonal space group P4(1)22 with cell dimensions a = b = 79.8, c = 99.9 angstrum. The crystals diffract to about 5 angstrum resolution.
|Number of pages||3|
|Publication status||Published - 17 Apr 1995|
- Base Sequence, Crystallization, Crystallography, X-Ray, DNA/chemistry, Molecular Sequence Data, Oligodeoxyribonucleotides/chemistry