Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation
Research output: Contribution to journal › Journal article › Research › peer-review
Tetrazine–trans-cyclooctene ligations are remarkably fast and selective reactions even at low micro-molar concentrations. In bioorthogonal radiochemistry, tools that enable conjugation of radioactive probes to pre-targeted vectors are of great interest. Herein, we describe the successful development of the first 11C-labelled tetrazine and its reaction with trans-cyclooctenol.
|Number of pages||3|
|Publication status||Published - 2013|