Development of a QSAR model for binding of tripeptides and tripeptidomimetics to the human intestinal di-/tripeptide transporter hPEPT1

Research output: Contribution to journalJournal articleResearchpeer-review

Rikke Andersen, Flemming Steen Jørgensen, Lars Olsen, Jon Våbenø, Karina Thorn, Carsten Uhd Nielsen, Bente Steffansen

The aim of this study was to develop a three-dimensional quantitative structure-activity relationship (QSAR) model for binding of tripeptides and tripeptidomimetics to hPEPT1 based on a series of 25 diverse tripeptides.
Original languageEnglish
JournalPharmaceutical Research
Volume23
Issue number3
Pages (from-to)483-92
Number of pages10
ISSN0724-8741
DOIs
Publication statusPublished - 2006

    Research areas

  • Caco-2 Cells, Drug Design, Humans, Intestinal Mucosa, Models, Biological, Peptides, Protein Binding, Protein Conformation, Quantitative Structure-Activity Relationship, Symporters

ID: 38393448