Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries
Research output: Contribution to journal › Journal article › Research › peer-review
Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.
|Journal||Acta Physiologica (Print)|
|Number of pages||12|
|Publication status||Published - Apr 2014|