Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine
Research output: Contribution to journal › Journal article › Research › peer-review
Erythrina alkaloids represent a rich source of complex polycyclic, bioactive natural products. In addition to their sedative and hypotensive effect, their curare-like activity and structural framework have made them attractive targets for synthetic and medicinal chemists. (+)-Dihydro-β-erythroidine (DHβE), the most potent nicotine acetylcholine receptor antagonist (nAChR) of the Erythrina family, is synthesized for the first time in 13 steps from commercially available material.
|Journal||Journal of the American Chemical Society|
|Publication status||Published - May 2019|