Evidence for CGRP re-uptake in rat dura mater encephali

Research output: Contribution to journalJournal articleResearchpeer-review

Saurabh Gupta, Dipak Vasantrao Amrutkar, Aydin Mataji, Hassan Salmasi, Anders Hay-Schmidt, Majid Sheykhzade, Karl Messlinger, Jes Olsen, Inger Jansen-Olesen

Calcitonin gene-related peptide (CGRP) is widely distributed in the trigeminovascular system and released from sensory fibres of the cranial dura mater upon noxious stimulation. Such release may be a mechanism underlying migraine headache. Based on data from guinea pig basilar artery preparations, we have here studied CGRP release and uptake in an organ preparation of the hemisected rat skull.
Original languageEnglish
JournalBritish Journal of Pharmacology
Volume161
Issue number8
Pages (from-to)1885-1898
Number of pages14
ISSN0007-1188
DOIs
Publication statusPublished - 2010

ID: 32642324